scholarly journals Study of drug utilization pattern in emergency medicine ward at a tertiary care teaching hospital

Author(s):  
Mamatha V. ◽  
Parashivamurthy B. M. ◽  
Suneetha D. K.

Background: The emergency department represents an important platform for conducting drug utilization studies as patients present with a wide spectrum of diseases in acute form. An irrational prescription adversely affects the prognosis and recovery of patients. Hence, the objective of our study was to evaluate the drug utilization pattern and to determine the rationality of prescription using WHO prescribing indicators in emergency medicine ward.Methods: After obtaining Institutional Ethical Committee approval, a prospective observational study was conducted over 2 months. The case records of 150 patients admitted to the emergency medicine ward, with a hospital stay of more than 24hrs were reviewed to analyze the prescription pattern during the initial 48hrs of admission. Case records of patients irrespective of age, sex and diagnosis were included in the study. Descriptive statistics were used to analyze the results (SPSS version 20).Results: A total of 1014 drugs were prescribed from 150 case records with a mean age of 47±18 years. An average of 6.76 drugs was prescribed per prescription; percentage of encounters with at least an antimicrobial was 115 (76.66%). Injections were prescribed in all patients (100%) and only 416 (41.02%) drugs were prescribed by generic name and 657 (64.79%) drugs abided to the WHO essential drug list. Majority of patients received anti-ulcerogenic drugs followed by antimicrobials.Conclusions: There was a tendency of polypharmacy with overuse of PPIs and antimicrobials. There is need to rationalize the drug therapy in terms of increasing prescription of drugs from essential drug list by generic name.

2019 ◽  
Vol 7 (1) ◽  
Author(s):  
Naresh Karki ◽  
Ruban Raj Joshi ◽  
Buddhi Kumar Shrestha ◽  
Pravin Prasad

Introduction: Drug utilization research is an important tool to facilitate rational use of drugs. In low income countries irrational use of drugs is a common problem like overuse of drugs and inappropriate use of antibiotics, leading to poor treatment outcome and increased burden of treatment. This study was conducted to provide understanding of drug utilization pattern by using WHO Core Prescribing Indicator. Methods: This study was conducted in Orthopedics and Obstetrics / Gynecology departments. Patients visiting these Out Patient Departments with at least one drug on prescription form were included in the study. Further, information related to WHO Core Prescribing Indicators were collected in pre-designed proforma. Results: Average number of drugs prescribed per prescription was 2.6. Means of number of drugs prescribed in Orthopedics and Obstetrics / Gynecology departments were 2.9 and 2.3 respectively (p < 0.001). Drugs prescribed in generic name and from essential drug list was 41.4% and 34.3% respectively. Prescription forms with generic name in Orthopedics department were significantly more compared to Obstetrics / Gynecology department (p = 0.00002). However, there was an increased tendency to prescribe drugs from essential drug list in Obstetrics / Gynecology department compared to Orthopedics department (p < 0.001). Conclusion: Drugs were prescribed by generic name and from essential drug list, but this was not sufficient to meet the ideal values of WHO Core Prescribing Indicator. Therefore, prioritization on prescribing drugs by generic name and from essential drug list by respective departments to achieve the standards of WHO needs to be encouraged.


Author(s):  
Manish B. Nandeshwar ◽  
Ashish D. Chakravorty

Background: Gynaecological diseases are common in India because of socioeconomic, hygienic and literacy problems. Gynaecological drugs are one of the strong selling drugs in pharmaceutical market. Drug utilization research facilitate appropriate use of drugs in patient, minimize the adverse event and lead to better patient outcome. So, the present study was carried out to examine the patterns of drug prescription.Methods: A retrospective, observational study was done by collecting the prescriptions of the patients who attended the Gynaecology out-patient department in our institute for the period of six months. Total 300 prescription were collected and analysed. Patient’s demographic data, total number and category of drugs prescribed, percentage of individual drug and their dosage forms, drugs prescribed by generic name, brand names and percentage of drugs prescribed from essential drug list were analysed.Results: The mean age of presentation was 36.6±10.98 years. Among infective group breast abscess were common and among non-infective cases dysmenorrhea was most common. Out of 754 drugs prescribed, minerals were most commonly prescribed (42.70%) followed by antimicrobials (24.53%). Tablet form were prescribed more commonly (96.02%) followed by capsules (2%) and injections (1.06%). The average no. of drugs per prescription was 2.51±1.26 SD. Percentage of drugs prescribed by generic name were 98.01% and drugs prescribed from essential drug list were 85.41%.Conclusions: The overall drug use pattern in our study correlates with various gynaecological diseases. Majority of the women from rural background depend on primary health services for gynaecological diseases in their areas so, strengthening of gynaecological health care services reduce the morbidity among the women from rural areas. 


2020 ◽  
pp. 1-4
Author(s):  
Shambo Samrat Samajdar ◽  
Ritabrata Mitra ◽  
Manotosh Sutradhar ◽  
Debasish Ghosh ◽  
Mrinal Pal ◽  
...  

Background: In India, asthma imposes a substantial burden; though the disease still remains under-recognized, underestimated and under-treated in masses.With a global need of promoting rational drug use in healthcare, drug utilization pattern studies could provide feedback to prescribers and help in fostering rational drug usage. The present study was planned to study the drug utilization pattern in patients of asthma in a tertiary care set-up in eastern India and to evaluate it with respect to GINA guidelines. Materials and Methods: The study was carried out over a period of one year where cases with confirmed diagnosis of asthma, who gave informed consent to participate were included.Drug usage pattern was determined in the light of drugs prescribed, mean drugs per prescription, percentage of drugs prescribed in generic name and having conformation to national essential drug list. Percentage of inhalational, injectable, fixed dose combination and antibiotics per prescription were noted. Data were checked for completeness and statistically analysed. Results: The present study included 370 participants. A total of 1514 drugs were prescribed, with 4.09 drugs per prescription. 12.55% of drugs prescribed were from national essential drug list. A total of 1031 anti-asthma drugs were prescribed with 2.8 anti-asthma drugs per prescription. Among the various classes of anti-asthma drugs, maximum prescribed were inhalational corticosteroids, followed by long acting inhalational beta 2 agonist and anti-leukotriene drugs. 96.5% of total patients were on inhalational drugs, with budesonide and formeterol being majorly prescribed. Conclusion: The usage pattern as assessed in our study was in conformation to GINA guidelines. Guidelines like GINA have enlightened physicians about the rational prescribing in asthmatic patients.


Author(s):  
Vijay Haribhau Mate ◽  
Satish Balaji Gonarkar ◽  
Anjum Mehmood Dhamani

Background: Drug utilization studies are useful for understanding the pattern of drug use in any particular healthcare set-up. This data gives an insight to improve the medical treatment at different layers in the health system. The oobjective of the present study was to assess drug utilization patterns by using core prescribing indicators of WHO and to assess most commonly observed skin disease in Dermatology out patients department (OPD) of tertiary care hospital.Methods: 246 prescriptions from Dermatology OPD were audited. Common skin diseases and the prescribing patterns were analysed from the prescriptions.Results: Average 2.4 drugs per prescription were seen in this study. 38.7%  drugs were from National Essential Drug List of India. All the drugs were prescribed by brand names. The fixed dose combinations accounted for 20.6% drugs prescribed. Dosage, dose and duration of treatment were written for 100% of prescriptions. Around 44 different skin diseases were diagnosed amongst 246 patients predominantly cutaneous fungal infections, acne, dermatitis, eczema and psoriasis. About 591 different drugs were used mainly corticosteroids (21%), antibiotics (17%), anti-allergic (16%), antifungals (11%). Common skin conditions receiving corticosteroids were dermatitis (9.9%), eczema (9.1%). Antibiotics (17%), antifungals (11%) and antivirals (1%) were commonly used antimicrobial agents. 55.2% drugs were administered topically while 44.6% received orally.Conclusions: Prescriptions revealed a higher incidence of fungal and bacterial infections. All the medications were prescribed rationally. All prescriptions had proper dosage form, frequency of administration, duration of therapy and diagnosis. However, prescriber should be motivated for prescription of generic drugs and those from essential drug list.


Author(s):  
Shobha P. ◽  
Messaline Sunitha

Background: ICU patients are exposed to more number of life saving drugs and face drug related problems like therapeutic failure, drug interactions and frequent adverse drug reactions. The cost of ICU hospitalisation and money spent on medicines is also a huge burden on these patients. A study of prescribing pattern in an ICU set up will serve as a medical audit to monitor and evaluate the prescribing practices to make it more rational and cost effective.Methods: A prospective observational study was carried out in a medical ICU of a tertiary care hospital. All the inpatients admitted in the medical ICU during the study period of 2 months were included in the study. The data obtained from the case sheets were used to assess the prescribing pattern and rationality of drug use.Results: A total of 101 patients were admitted in 2 months. The most common illness for which the patients (22) were admitted was respiratory problems. Average number of drugs per prescription was 6.9. Cardiovascular system (23.9%) drugs were the most frequently prescribed. Pantoprazole (77) was the single most commonly prescribed drug. 40% of the drugs were prescribed from the essential drug list. The average cost of medicines incurred per person in our study was 5126.33 in INR.Conclusions: Polypharmacy and unwanted prescription of proton pump inhibitors can be avoided by prescribing more generics and drugs from essential drug list.


2019 ◽  
Vol 7 (7) ◽  
pp. 1203-1208 ◽  
Author(s):  
Asmatanzeem Bepari ◽  
Nayana Sakre ◽  
Ishrat Rahman ◽  
Shaik Kalimulla Niazi ◽  
Asmabi M. Dervesh

BACKGROUND: Cancer is a major burden and threat to global society. A wide range of chemotherapeutic agents is extensively used to treat cancer at different stages. Inappropriate drug use may also lead to the raised cost of medical care, adverse drug effects, and patient mortality. Hence, in recent years, drug utilisation studies have become a potential tool to be used in the evaluation of different health care systems including cancer. AIMS: The objectives of the study were to identify the various types of cancer, the commonly prescribed drugs, rational use of anticancer drugs, and analyse the prescribing indicators in a tertiary care government hospital of India. MATERIAL AND METHODS: Newly diagnosed cancer and/or known case of carcinoma of either sex which required treatment/on treatment with chemotherapy aged > 18 yrs admitted in Radiotherapy Department from April 2016 to September 2016 were included in the study and analysed for prescribing indicators. RESULTS: The head & neck cancers were the prevalent cancers observed with more preponderance among males. Most of the patients were prescribed with a single anticancer drug. Cisplatin was the most commonly used cytotoxic drug followed by carboplatin, and antimetabolites. The most commonly used adjuvant drugs in our study were anti-emetics and anti-peptic ulcer drugs. Over 82% of anticancer agents were taken from the essential drug list and were prescribed in generic names, indicating rational use. CONCLUSION: Over 82% of anticancer agents were taken from the essential drug list and were prescribed in generic names, indicating rational use.


Author(s):  
Chandan N. G. ◽  
Ranganathan T. ◽  
Nagabushan H.

Background: Drug utilization studies are an important tool in evaluating the rationality of therapeutic practice and also it is said to improvise the therapeutic use of drugs. The present study will be undertaken to evaluate the drug utilization pattern in the department of Radiotherapy.Methods: This was a prospective, observational study that was undertaken in the department of Radiotherapy in a tertiary care teaching hospital. The study was conducted for a period of 6 months after obtaining permission from Institutional Ethical Committee. The study was conducted among cancer patients undergoing radiotherapy. The data was collected from the patient case records and was analyzed as per the WHO prescribing indicators.Results: In the present study it was observed that the average number of drugs prescribed per encounter was 7.7. The drugs prescribed by generic name were 41.4%. Percentage of encounters with an antibiotic prescribed was 100. Percentage of encounters with an injection prescribed was 20.5%. Percentage of drugs prescribed from essential drugs list was 35.8%.Conclusions: Drug utilization studies helps in modifying the prescription pattern and helps in making the drug usage more rational.


2013 ◽  
Vol 2 (2) ◽  
pp. 13-17
Author(s):  
Mohammad Afsan ◽  
Muhammad Mahbubul Alam ◽  
Nushrat Noor ◽  
AH Hamid Ahmed

A cross-sectional descriptive study was carried out among individuals attending the Out Patient Department (OPD) of Medicine, Paediatrics, Dermatology & Venerology, ENT, Orthopaedics and Gynaecology & Obstetrics from December 2011 to March 2012 in East-West Medical College Hospital, Dhaka, Bangladesh, to see the patterns of prescriptions using World Health Organization (WHO) core prescribing indicators and some additional indices. A total of 300 prescriptions were collected and analyzed by the 3rd year MBBS students in this study. The average number of drugs per encounter was 3.22 and 5.33% drugs were prescribed by generic name. Use of antibiotic (48.67% of encounters) was frequent, but injection use (6.67% of encounters) was within the recommendation of WHO. Only 26.09% drugs were prescribed from national essential drug list. Percentage of encounters with a NSAID, an anti-ulcerant, an antihistamine, a calcium preparation and a multivitamin & multimineral prescribed were 44.33%, 43.33%, 22.33%, 19.33% and 15.67% respectively. So, the findings from current study showed a trend towards inappropriate prescribing, particularly the over-prescribing of antibiotics and under-prescribing of generic drugs and also most of the drugs were prescribed out of national essential drug list. Hence, there would be needed for effective intervention program to encourage the physicians and healthcare providers in promoting more appropriate drug use. DOI: http://dx.doi.org/10.3329/updcj.v2i2.15483 Update Dent. Coll. j: 2012; 2 (2): 13-17


2016 ◽  
Vol 7 (4) ◽  
pp. 80-83
Author(s):  
Pratyay Pratim Datta ◽  
Anju Prasad ◽  
Chaitali Pattanayak ◽  
Ashok Singh Chouhan ◽  
Parbaty Panda

Background: Drug prescription pattern for the treatment of falciparum malaria differs widely from place to place; but there is also some intra organizational variation of prescription pattern of anti-malarial drugs for the treatment of falciparum malaria.Aims and Objectives: The present study was planned to study the drug utilization pattern for the treatment of falciparum malaria in a tertiary care teaching hospital in eastern India.Materials and Methods: It was a hospital based study conducted in the department of medicine among the patients admitted with confirmed diagnosis of falciparum malaria. Drugs prescribed, average number of drugs per prescription, percentage of drugs prescribed in generic name, percentage of prescription with co-prescription of antibiotics, percentage of prescription having at least an injection prescribed, percentage of drugs prescribed from essential drug list or formulary and average drug cost per prescription are the parameters studied in this study.Results: Average number of drugs per prescription in the present study was 3.96. Artesunate and Mefloquine were the most common anti-malarial drugs prescribed among study subjects. 22.9% patients received oral Chloroquine as anti-malarial drug. 43.3% prescriptions had antibiotics co-prescribed. Only 16.9% drugs were prescribed in generic name. 85.4% of the prescribed drugs were from essential drug list. Average drug cost per patient was Rs. 282/- with minimum of Rs. 55/- and maximum of Rs. 1750/-.Conclusion: Though Artesunate combination therapy is getting popularized gradually but a sizable proportion of patients (22.9%) were prescribed with oral Chloroquine therapy. Generic prescription of drugs should be encouraged among the physicians. Multi-centric study regarding drug prescription can give a broader picture in changing scenario.Asian Journal of Medical Sciences Vol.7(4) 2016 80-83


Author(s):  
Sini K. ◽  
Mohammed Basheer ◽  
Shaikh Ubedulla Shaikh Iqbal Daud ◽  
Divya G. Krishnan

Background: Geriatric population due to the age related changes in pharmacokinetics and pharmacodynamics and the presence of comorbidities is vulnerable to drug interactions, adverse effects and high cost of therapy. This necessitates a periodic review of DU pattern in the geriatric population to ensure safe and effective treatment for them. The present study was undertaken to evaluate the DU pattern for medical conditions among the geriatric population in the Orthopaedic outpatient department (OPD) of a tertiary care hospital in Kerala.Methods: In this cross sectional observational study conducted in the Orthopaedics OPD of a tertiary care hospital, prescriptions were collected from patients attending the Orthopaedics OPD randomly over a period of 6 months. Out of these, prescriptions of male and female patients of age more than 60 years were sorted and analysed using World Health Organization drug prescribing indicators as well as additional parameters and the data was presented in the form of frequency and percentages using tables and charts.Results: A total of 800 prescriptions were collected and studied of which 76 (9.5%) belonged to patients from the geriatric population. Majority of the patients were in the age group of 61-70years (52.63%). Spondylosis (42.10%) was the most common indication for patients attending Orthopaedics OPD. Average number of drugs per prescription was 3.05 with a range between 1 and 5. Only 5.17% drugs were prescribed using generic name. Utilization from the essential drug list was 39.65%. The percentage of encounters in which an antibiotic and injection prescribed was 0% and 10.34% respectively. Of the total drugs prescribed 35% were FDCs. The most routinely prescribed drugs among the various classes were NSAIDs 34% followed by gastroprotectives (25%). The assessment of prescriptions with regard to completion and legibility was satisfactory.Conclusions: Current study pointed out deficiencies like polypharmacy, low prescribing of drugs by generic names, low prescribing of drugs from the essential drug list and higher use of FDCs. Use of antibiotics and injections was satisfactory and acceptable. Legibility and completion of prescription format was largely satisfactory. Proper strategies to rectify these deficiencies can ensure safe and effective treatment for geriatric patients.


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