scholarly journals A retrospective analysis of adverse drug reaction reported in a tertiary care hospital

2017 ◽  
Vol 6 (5) ◽  
pp. 1146
Author(s):  
Kirti Saxena ◽  
Chaitali Tailor ◽  
Chaitali Mehta ◽  
Paresh Gajera ◽  
S. K. Srivastava
Keyword(s):  
Tertiary Care Hospital ◽  
Diclofenac Sodium ◽  
Tertiary Care ◽  
Pharmacovigilance Centre ◽  
Pulmonary Medicine ◽  
Care Hospital ◽  
Dermatology Department ◽  
Medicine Department ◽  
Causative Drug ◽  
Male Patients

Background: The adverse drug reactions (ADRs) reported to pharmacovigilance centre in tertiary care hospital was analysed to find out the incidence and causality.Methods: This was a retrospective study to analyse the ADR reported at pharmacovigilance centre after ethical clearance from Institutional Ethic Committee (IEC). ADR data were analysed and ADRs were categorized as department-wise, system affected and causative drug. The causality of each ADR was assessed by WHO-UMC scale.Results: The majority of patients who had suffered from ADRs were between 19-64 years of age (94.2%) and male patients (58.6%) were affected more than female (41.4%). Pulmonary medicine department has reported highest number of ADR followed by dermatology department. Skin (46.5%) was most affected system followed by gastrointestinal (30.45%), CNS (21.26%), respiratory (9.0%) and remaining systems. Rifampicin (13.79%) shows the largest numbers of ADR followed by zidovudine (13.21%), nevirapine (12.64%) and diclofenac sodium (8.0%). The maximum ADRs reported were probable (94.8%) followed by possible (5.2%).Conclusions: In conclusion, the skin was most affected system followed by gastrointestinal, central nervous and respiratory system. Rifampicin has caused maximum ADRs followed by zidovudine, nevirapine and diclofenac sodium. The causality analyses showed that majority of ADRs were probable (94.8%) while remaining falls in possible (5.2%) category.

scholarly journals Tele-health during COVID-19 Pandemic Lockdown in Pakistan -Experience of a Tertiary Care Hospital

2020 ◽  
Keyword(s):  
Health Program ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Pulmonary Medicine ◽  
Care Hospital ◽  
Medicine Department ◽  
Institutional Management ◽  
Care Services ◽  
Primary Care Services ◽  
Respiratory Complaints

Introduction: COVID-19 (Coronavirus Disease 2019) caused by SARS-Cov-2 has quickly multiplied since its outbreak in humans. The utilization of telemedicine came to the fore in this dire situation when it is absolutely necessary to maintain social distancing. This study has been done to highlight the implementation of tele-health program among the general population during COVID-19 pandemic in our setting. Methods: The current study presents the experience of a tertiary care hospital in Pakistan in terms of utilization pattern and patients’ clinical complaints dealt with in Tele-health Program. The Tele-health program was initiated by family medicine department at Liaquat National Hospital, Karachi in collaboration with internal medicine, pulmonary medicine and department of infectious disease. The program was approved by institutional management committee. The current study presents an audit of tele-health calls received during last week of March-2020 till April 2020. The data was obtained from structured clinical consultations notes recorded at the time of receiving patients’ call. Data was analyzed on SPSS version 20. Results: We analyzed data of a total of 459 patients who availed tele-health services during last week of March-2020 till April-2020. The median no. of calls was approximately 12 per day. Almost half of patients were between 18 to 39 years (n= 224, 48.40%). 407 (88.67%) of the consultations were done by initial patients. Total 482 complaints were received including 9 requests for direct referral to specialized clinics. Respiratory complains were most frequently encountered (212, 46.19%). Among the 212 respiratory complaints, 103 (47.64%) were COVID-19 related complaints. Out of 459, only 7 (1.5%) were severe enough to be advised to visit hospital. Conclusion: It is very crucial to provide timely essential quality primary care services during a lockdown situation to avoid delay in healthcare, avoid complications due to delay and hence exhausting resources after the lockdown. Telemedicine can provide the bridging solution, enabling people to access judicious healthcare from the comfort of their homes.

scholarly journals A STUDY TO ASSESS KNOWLEDGE ON TUBERCULOSIS SPREAD IN PATIENTS ATTENDING OUTPATIENT DEPARTMENT IN A TERTIARY CARE HOSPITAL IN NALGONDA REGION

2020 ◽  
Vol 8 (9) ◽  
pp. 858-861
Author(s):  
V. Anusha ◽  
Keyword(s):  
Educational Level ◽  
Prevention And Control ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Pulmonary Medicine ◽  
Care Hospital ◽  
Exclusion Criteria ◽  
Medicine Department ◽  
The World ◽  
And Control

Introduction: India contributes one fourth of total Tuberculosis burden in the world .Poor awareness among public and negligence towards its prevention and control are cause of this widespread. Methodology: 300 people were selected among all the patients attending pulmonary medicine department after considering inclusion and exclusion criteria . Results: There was poor knowledge about the cause, spread of tuberculosis and disposal of sputum .Association between knowledge and age and education was observed. Conclusion: By increasing health education and educational level the awareness about the spread and prevention can be achieved.

A Study on Day Care Transfusion Services in Transfusion Medicine Department of a Tertiary Care Hospital

2019 ◽  
Vol 3 (01) ◽  
pp. 12-15
Author(s):  
Farida Parvin ◽  
Mohammed Abdul Quader ◽  
Daanish Arefin Biswas ◽  
Mohammed Ali ◽  
Bepasha Naznin ◽  
...  
Keyword(s):  
Day Care ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Fresh Frozen Plasma ◽  
Transfusion Practice ◽  
Care Hospital ◽  
Transfusion Medicine ◽  
Blood Components ◽  
Medicine Department ◽  
Long Term Study

Background: Transfusion of blood components and derivatives in day care unit is an eminent part of management of transfusion dependent patients. Day care transfusion service is an alternative to hospital admission and beneficial for those patients who receive blood more frequently for their survival. Objective: The aim of present study is to assess Transfusion Services provided in a Day Care Unit (DCU) of a tertiary care hospital. Methodology: This study was carried out in DCU of Transfusion Medicine Department, Bangabandhu Sheikh Mujib Medical University, (BSMMU) at Dhaka during January 2014 to December 2014. Data were collected from record registers. Recorded retrospective data were analyzed as percentage and proportion. Results: Total recipients were 718. Among those 424 (59.05%) were male and 294 (40.95%) were female and 562 (78.27%) were between 10 to 40 years. A total of 8587 units of blood components were used during this period. Red Cell Concentrate was most commonly utilized product 6388 (74.39%) followed by Fresh Frozen Plasma (FFP) 1360 (15.83%), Platelet Concentrate 544 (6.33%), Whole blood 260 (3.05%) and Cryoprecipitate 35 (0.40%). Transfusion was required more frequently in thalassaemic 365(50.88%) patients. Haemophilia 77(10.72%) and aplastic anaemia patients 49 (6.82%) were next high. The main transfusion reaction observed during transfusion was febrile non-haemolytic reactions. Conclusion: For increasing use of specific blood product and hassle-free transfusion services this kind of day care unit services should be strengthened. Long term study of this kind will help us to develop safe clinical transfusion practice.

scholarly journals Evaluation of adverse drug reactions of anti-tubercular drugs in the treatment of tuberculosis in tertiary care hospital

2020 ◽  
Vol 9 (9) ◽  
pp. 1430
Author(s):  
Krishnakanth K. ◽  
Jagadeesh A. ◽  
Swetha T. D.
Keyword(s):  
Adverse Drug Reaction ◽  
Adverse Drug Reactions ◽  
Adverse Drug Events ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Drug Reactions ◽  
Cross Sectional ◽  
Medicine Department ◽  
Study Results

Background: Adverse drug reactions are very common among patients on anti-tubercular treatment. Hence, the current study was done to evaluate the adverse drug reaction (ADR) profile in patients receiving anti-tubercular treatment (ATT).Methods: A 6 months prospective, cross-sectional observational study was performed in collaboration with Pulmonology Medicine department. WHO-UMC scale and Naranjo scale was used to evaluate the ADRs.Results: Ninety-two patients receiving ATT presented with 113 adverse drug events (ADE). Males were more affected than females. DOTS category-1 regimen was mostly responsible for ADE. Addition of drugs for the management of ADR events was done.Conclusions: The study results show more ADRs related to ATT demanding increased collaboration between NTEP 2020 and Pharmacovigilance Programme of India to enhance drug safety in this field.

scholarly journals Prevalence and anti-microbial susceptibility pattern of methicillin resistant Staphylococcus aureus at a tertiary care hospital

2020 ◽  
Vol 9 (9) ◽  
pp. 1371
Author(s):  
Rajalakshmi Ramesh ◽  
Padmavathi Karunakaran ◽  
Dhivya Govindasamy ◽  
Kamalavarshini Paramasivamsasanger ◽  
Prema Mariappan
Keyword(s):  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Susceptibility Pattern ◽  
Methicillin Resistant ◽  
Male Patients ◽  
Phenotypic Methods ◽  
And Staphylococcus Aureus

Background: To study about the prevalence and anti-microbial susceptibility pattern of methicillin resistant Staphylococcus aureus (MRSA).Methods: Totally 110 non-repetitive Staphylococcus aureus isolates were enrolled in this study. Isolates from different clinical specimens like pus and blood obtained from patients in tertiary care hospital and Staphylococcus aureus was identified by conventional phenotypic methods. Complete antibiotic susceptibility testing of all MRSA isolates was determined by Kirby-Bauer disc diffusion method.Results: Out of 110 isolates of S. aureus 60 were found to be methicillin-resistant Staphylococcus aureus (MRSA). The prevalence of MRSA was 54%. Out of 60 isolates, male patients 37 (63%) and female patients are 22 (37%). Maximum numbers of isolates 25 (41.6%) were from the age group of 51 to 60 years. Among these 60 isolates, all of them were found to be resistant to penicillin and oxacillin. In contrast, 98% of the isolates were found to be sensitive to linezolid. The sensitivity to chloramphenicol 70%, co-trimoxazole 60%, amikacin 58%, clindamycin 43%, ciprofloxacin 38%, erythromycin 25%.Conclusions: The observed prevalence rate was 54%. Linezolid showed the best therapeutic outcome against MRSA. Active screening plays an important role in control of MRSA.

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