scholarly journals Neuroleptic malignant syndrome: case report

2021 ◽  
Vol 11 (1) ◽  
pp. 70
Author(s):  
Murshid C. P. ◽  
Bande Shareef ◽  
Parlapalli Hema
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Case Report ◽  
Respiratory Failure ◽  
Trigeminal Neuralgia ◽  
Neuroleptic Malignant Syndrome ◽  
Antipsychotic Drugs ◽  
Life Threatening ◽  
History Of ◽  
Neurologic Emergency

Neuroleptic malignant syndrome (NMS) is an infrequent, but potentially life-threatening neurologic emergency associated with the use of neuroleptic or antipsychotic drugs. A 43 years old male with a history of trigeminal neuralgia developed Neuroleptic malignant syndrome while receiving Carbamazepine and Amitryptylline. Treatment is mainly supportive and includes withdrawal of the neuroleptic medication and, possibly, administration of drugs such as dantrolene and bromocriptine. Complications of NMS include acute renal failure and acute respiratory failure. The possible etiologies, triggering factors and treatment are discussed with reference to existing literature.

scholarly journals Asymptomatic mediastinal extra-adrenal paraganglioma as a cause of sudden death: a case Report

2019 ◽  
Vol 14 (1) ◽  
pp. 564-567
Author(s):  
Qiancheng Xu ◽  
Yingya Cao ◽  
Hongzhen Yin ◽  
Rongrong Wu ◽  
Tao Yu ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Case Report ◽  
Respiratory Failure ◽  
Pressure Drop ◽  
Thoracic Cavity ◽  
Severe Hypotension ◽  
Life Threatening ◽  
History Of ◽  
Posterior Mediastinal ◽  
Extra Adrenal Paraganglioma

AbstractA 23-year-old female patient was referred for treatment of a posterior mediastinal tumour. There was no history of hypertension or headache and no other complaints. The patient’s blood pressure increased to 210/125 mmHg after surgically manipulating the tumour, subsequently reversing to severe hypotension (25/15 mmHg) immediately after the tumour was removed. The life-threatening and irreversible blood pressure drop was difficult to treat with fluid and vasopressors, and the patient ultimately died of cardio-respiratory failure. Asymptomatic paraganglioma can be non-functional but can also be fatal. For any lump in the thoracic cavity, paraganglioma should be ruled out.

scholarly journals Ascites, a New Cause for Bilateral Hydronephrosis: Case Report

2009 ◽  
Vol 9 ◽  
pp. 1035-1039 ◽  
Author(s):  
Deepika Jain ◽  
Smrita Dorairajan ◽  
Madhukar Misra
Keyword(s):  
Renal Failure ◽  
Renal Function ◽  
Acute Renal Failure ◽  
Liver Cirrhosis ◽  
Case Report ◽  
Abdominal Ultrasound ◽  
Back Pressure ◽  
Alcoholic Liver Cirrhosis ◽  
Bilateral Hydronephrosis ◽  
History Of

Bilateral hydronephrosis secondary to urinary obstruction leads to a buildup of back pressure in the urinary tract and may lead to impairment of renal function. We present a case of a 57-year-old male with a history of alcoholic liver cirrhosis, who presented with tense ascites and acute renal failure. Bilateral hydronephrosis was seen on abdominal ultrasound. Multiple large-volume paracenteses resulted in resolution of hydronephrosis and prompt improvement in renal function.

Risperidone-Induced Neuroleptic Malignant Syndrome: A Case Report and Review

1996 ◽  
Vol 41 (1) ◽  
pp. 52-54 ◽  
Author(s):  
Gb Meterissian
Keyword(s):  
Case Report ◽  
Side Effects ◽  
Neuroleptic Malignant Syndrome ◽  
Clinical Features ◽  
Prior History ◽  
Extrapyramidal Side Effects ◽  
Life Threatening ◽  
History Of ◽  
Life Threatening Complication ◽  
The One

Objectives: 1. To report the case of a 53-year-old patient who developed neuroleptic malignant syndrome (NMS) — a rare but potentially life-threatening complication of neuroleptic therapy — 4 days after treatment with risperidone was initiated. 2. To review previously reported cases of NMS associated with risperidone. Methods: A computerized search of several databases, including MEDLINE, was conducted to find all previously reported cases of NMS with risperidone. Results: Five reported cases of risperidone-induced NMS were found in the literature. All cases including the one reported here displayed typical clinical features of NMS and all 6 patients had a prior history of extrapyramidal side effects and/or NMS. Age and duration of exposure to risperidone did not seem to be of significance. Conclusions: These cases illustrate that clinicians should be on the lookout for risperidone-induced NMS.

scholarly journals Acute Oxalate Nephropathy Due to Bilimbi Poisoning: A Case Report

2016 ◽  
Vol 4 (1) ◽  
pp. 33-35
Author(s):  
Rajat Das Gupta ◽  
Debashis Datta ◽  
Debashis Datta ◽  
Suranjan Kumar.
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Case Report ◽  
Oxalic Acid ◽  
Calcium Oxalate ◽  
Elderly Woman ◽  
Biochemical Study ◽  
Calcium Oxalate Crystals ◽  
History Of ◽  
Oxalate Nephropathy

Background: The concentrated juice made from Averrhoa bilimbi is rich in oxalic acid. It can cause acute oxalate nephropathy by blocking the tubules with calcium oxalate crystals. Case: An elderly woman was admitted to the hospital with a history of swelling of the legs, facial puffiness, and abdominal distention. Her biochemical study revealed features of acute renal failure. She gave history of taking half liter of bilimbi juice. Renal biopsy confirmed it was a case of acute oxalic nephropathy, which made it the second case of acute oxalic nephropathy due to ingestion of bilimbi juice ever reported from Bangladesh. Conclusion: It is not safe to consume high oxalate-containing fruits in large quantities.

scholarly journals Neuroleptic Malignant Syndrome: Diagnostic and Therapeutic Dilemmas

2005 ◽  
Vol 16 (1) ◽  
pp. 9-13 ◽  
Author(s):  
Abebaw Fekadu ◽  
Jonathan I. Bisson
Keyword(s):  
Renal Failure ◽  
Respiratory Failure ◽  
Neuroleptic Malignant Syndrome ◽  
Dopaminergic System ◽  
Early Recognition ◽  
Delayed Diagnosis ◽  
Antipsychotic Medications ◽  
Comprehensive Management ◽  
Life Threatening

Neuroleptic malignant syndrome (NMS) is a life threatening medical state complicating the use of antipsychotic medications and other drugs that affect the dopaminergic system on administration or withdrawal. The condition was recognised nearly half a century ago, shortly after the discovery of antipsychotic medications. However, there are still no systematic studies about NMS. There are no definitive guidelines on its treatment. Although early recognition is emphasised and usually possible, delayed diagnosis is not rare. We here report on a case of NMS complicated by renal failure, and possibly respiratory failure. The report underscores the seriousness of delayed diagnosis and puts forward a comprehensive management recommendation based on our experience and the existing literature.

Complications of Reperfusion in Acute Aortic Artery Occlusion Following Saddle Embolization Originating from an Atrial Myxoma

Vascular ◽  
2004 ◽  
Vol 12 (3) ◽  
pp. 202-205 ◽  
Author(s):  
Tahir Ali ◽  
J. Castro ◽  
C.P. Young ◽  
K.G. Burnand
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Limb Ischemia ◽  
Artery Occlusion ◽  
Acute Onset ◽  
Atrial Myxoma ◽  
Cardiac Massage ◽  
Life Threatening ◽  
History Of ◽  
Bilateral Lower Limb

A 58-year-old man presented to the hospital with an 8-hour history of acute-onset bilateral lower limb ischemia. A large saddle embolus had occluded the aorta and could not be removed by balloon endarterectomy through the femoral arteries. Successful open aortic and femoral thromboembolectomy followed by extensive fasciotomies was accompanied by severe reperfusion injury. Life-threatening hyperkalemia was associated with three episodes of intraoperative ventricular fibrillation and ventricular tachycardia requiring cardiac massage and defibrillation. A dextrose-insulinbicarbonate infusion was required to correct the hyperkalemia. Rhabdomyolysis developed at 24 hours, causing marked myoglobinuria and acute renal failure, which required hemofiltration. Histology of the recovered embolus confirmed an atrial myxoma, and when the patient had fully recovered, open cardiac surgery was carried out to resect the tiny stump of residual myxoma. Rhabdomyolysis associated with a myxomatous saddle embolus has not been previously reported. This case highlights the need for pre- and perioperative measures to be taken to overcome hyperkalemia and acute renal failure when revascularizing acute, massive, prolonged ischemia of the lower body.

Rhabdomyolysis with Acute Renal Failure and Deep Vein Thrombosis Induced by Antipsychotic Drugs: A Case Report

2015 ◽  
Vol 48 (07) ◽  
pp. 265-267 ◽  
Author(s):  
I. Jullian-Desayes ◽  
A. Roselli ◽  
C. Lamy ◽  
M. Alberto-Gondouin ◽  
N. Janvier ◽  
...  
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Deep Vein Thrombosis ◽  
Case Report ◽  
Antipsychotic Drugs ◽  
Vein Thrombosis ◽  
Deep Vein

Acute Renal Failure Secondary to Pyelonephritis

PEDIATRICS ◽  
1996 ◽  
Vol 97 (5) ◽  
pp. 742-743
Author(s):  
Mary Ellen Turner ◽  
Jonathan Weinstein ◽  
Kanwal Kher
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Case Report ◽  
Medical Center ◽  
Solitary Kidney ◽  
The Other ◽  
Indwelling Catheter ◽  
National Medical ◽  
History Of ◽  
Predisposing Conditions

Pyelonephritis is an unusual cause of acute renal failure in children with an anatomically normal urinary tract and no other predisposing conditions. On the other hand, acute renal failure due to acute pyelonephritis has been reported in adults, and is often associated with pregnancy, solitary kidney, indwelling catheter or use of nonsteroidal medications.1-3 We report the case of a 12-year-old girl with normal renal anatomy and no known predisposing conditions who developed acute renal failure during the course of acute bacterial pyelonephritis, and who recovered completely after appropriate antibiotic therapy. CASE REPORT A previously healthy 12-year-old female was admitted to the Children's National Medical Center with a 1-week history of vomiting, diarrhea, and abdominal cramping.

scholarly journals Contrast-Induced Rhabdomyolysis Occurring after ERCP in a Patient with Pancreatic Cancer: A Case Report

2020 ◽  
Author(s):  
Natassja Moriarty ◽  
Jonathan Moriarty ◽  
John Keating
Keyword(s):  
Skeletal Muscle ◽  
Pancreatic Cancer ◽  
Renal Failure ◽  
Creatine Kinase ◽  
Acute Renal Failure ◽  
Case Report ◽  
Mortality Rate ◽  
Appropriate Treatment ◽  
Threatening Condition ◽  
Life Threatening

Objective: We present a patient with pancreatic cancer who developed weakness, acute renal failure and significantly raised creatine kinase levels post-ERCP and who was assessed as having contrast-induced rhabdomyolysis. Results: The patient underwent haemofiltration and ultimately succumbed to his condition. Conclusion: Rhabdomyolysis is a potentially life-threatening condition which occurs because of damage to skeletal muscle, with release of myoglobin and electrolytes into the circulation. The mortality rate is 59% in severe cases, despite appropriate treatment.

scholarly journals Overlapping of Serotonin Syndrome with Neuroleptic Malignant Syndrome due to Linezolid-Fluoxetine and Olanzapine-Metoclopramide Interactions: A Case Report of Two Serious Adverse Drug Effects Caused by Medication Reconciliation Failure on Hospital Admission

2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Faizan Mazhar ◽  
Shahzad Akram ◽  
Nafis Haider ◽  
Rafeeque Ahmed
Keyword(s):  
Case Report ◽  
Hospital Admission ◽  
Neuroleptic Malignant Syndrome ◽  
Medication Reconciliation ◽  
Serotonin Syndrome ◽  
Drug Effects ◽  
Hospital Treatment ◽  
Adverse Drug Effects ◽  
Life Threatening ◽  
History Of

Antipsychotic and antidepressant are often used in combination for the treatment of neuropsychiatric disorders. The concomitant use of antipsychotic and/or antidepressant with drugs that may interact can lead to rare, life-threatening conditions such as serotonin syndrome and neuroleptic malignant syndrome. We describe a patient who has a history of taking two offending drugs that interact with drugs given during the course of hospital treatment which leads to the development of serotonin syndrome overlapped with neuroleptic malignant syndrome. The physician should be aware that both NMS and SS can appear as overlapping syndrome especially when patients use a combination of both antidepressants and antipsychotics.

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