scholarly journals A case of amniotic fluid embolism and its sequelae during COVID-19 pandemic: a success story

Author(s):  
Anish Kumar Vishal ◽  
Dinesh Bhasin ◽  
Krishna Prasad

Amniotic fluid embolism (AFE) is an unforeseeable, life-threatening complication of pregnancy with an extremely high mortality rate. This is a complex disorder classically characterized by the abrupt onset of hypoxia, hypotension and consumptive coagulopathy. We experienced a patient who underwent caesarean delivery because of sudden cardiovascular collapse. Intra op she had DIC and was hemodynamically unstable. Surgery was able to complete with inotropes and vasopressors. In subsequent post op period, she had sepsis with MODS. The diagnosis of amniotic fluid embolism was made after other differential diagnosis had been ruled out.  The successful outcome in our case is attributable to early recognition with immediate delivery of the fetus, high-grade resuscitation, timely hysterectomy and aggressive treatment of coagulopathy by blood and blood-products, involvement of multidisciplinary team, constant supervision by nursing staff with positive approach. From a grim situation of near death, the final outcome was a successful story. 

2019 ◽  
Vol 5 (1) ◽  
Author(s):  
Yuki Kinishi ◽  
Chiyo Ootaki ◽  
Takeshi Iritakenishi ◽  
Yuji Fujino

Abstract Background Amniotic fluid embolism (AFE) is a life-threatening obstetric emergency. Because the maternal mortality associated with AFE is very high, early recognition and prompt treatment are important for improving the prognosis. We report a case of amniotic fluid embolism successfully treated by multidisciplinary treatment. Case presentation A 39-year-old woman with fetal congenital heart anomaly and polyhydramnios was scheduled for induction of delivery at 37 weeks of gestation with labor epidural analgesia. Uncontrollable bleeding occurred 30 min after vaginal delivery. Based on the clinical diagnosis of AFE, massive blood transfusion, insertion of an aortic occlusion balloon catheter, and hysterectomy was performed. Total blood loss was 12,000 mL. The diagnosis of AFE was confirmed by pathological examination. She was discharged with no complications. Conclusion We report a case of AFE who were rescued by prompt diagnosis and treatment.


2011 ◽  
Vol 14 (3) ◽  
pp. 157 ◽  
Author(s):  
Michael S. Firstenberg ◽  
Erik Abel ◽  
Danielle Blais ◽  
Katja Turner ◽  
Mona Halim-Armanios ◽  
...  

Amniotic fluid embolism is usually a life-threatening complication of an otherwise healthy pregnancy. Medical management of the coagulopathy and cardiovascular collapse is challenging and is often unsuccessful. We present a case and advocate the use of temporary circulatory support and pulmonary embolectomy in what would otherwise have been a fatal scenario.


Author(s):  
Milad Darrat ◽  
Brian Gilmartin ◽  
Carmel Kennedy ◽  
Diarmuid Smith

Summary Acute respiratory distress syndrome (ARDS) is a rare but life-threatening complication of diabetic ketoacidosis (DKA). We present the case of a young female, with no previous diagnosis of diabetes, presenting in DKA complicated by ARDS requiring extra corporeal membrane oxygenation (ECMO) ventilator support. This case report highlights the importance of early recognition of respiratory complications of severe DKA and their appropriate management. Learning points ARDS is a very rare but life-threatening complication in DKA. The incidence of ARDS remains unknown but less frequent than cerebral oedema in DKA. The mechanism of ARDS in DKA has multifactorial aetiology, including genetic predisposition. Early recognition and consideration of rare pulmonary complication of DKA can increase survival rate and provide very satisfactory outcomes. DKA patients who present with refractory ARDS can be successfully rescued by ECMO support.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Halley P. Crissman ◽  
Charisse Loder ◽  
Carlo Pancaro ◽  
Jason Bell

Abstract Background Amniotic fluid embolism (AFE) is a rare, life threatening obstetric complication, often associated with severe coagulopathy. Induced abortions are extremely safe procedures however complications including AFE can occur. Case presentation A 29-year-old previously healthy woman, gravida 1 para 0, presented for a scheduled second trimester induced abortion via dilation and evacuation at 22-weeks gestation. The case was complicated by a suspected AFE with associated profound coagulopathy. Viscoelastic point-of-care coagulation analysis was used to successfully and swiftly guide management of her coagulopathy. Conclusion AFE can occur in the setting of induced abortion. This case report suggests viscoelastic point-of-care coagulation analyzers may aid in the management of pregnancy-related coagulopathy by providing faster coagulation assessment than laboratory testing, and facilitating timely, targeted management of coagulopathy.


2011 ◽  
Vol 93 (4) ◽  
pp. e15-e16 ◽  
Author(s):  
Jagwinder Dhaliwal ◽  
Ajanta Jayatunga

Phlegmasia cerulea dolens (PCD) is a limb-threatening venous disorder involving massive proximal venous thrombosis. The clinical manifestations are of oedema, cyanosis and pain of lower extremity. Patients presenting with PCD have an underlying pathological condition that predisposes to the thrombotic process. We report a diabetic patient who presented with PCD and septicaemia due to a spontaneous psoas abscess. Anticoagulation with heparin and treatment of the underlying psoas abscess led to complete resolution of symptoms. An understanding of the underlying pathological process responsible is vital to early recognition and successful outcome in this rare limb- and life-threatening venous disorder.


Author(s):  
Noorazizah Arsad ◽  
Kah Teik Chew ◽  
Nur Azurah Abdul Ghani ◽  
Hui Jan Tan ◽  
Norasyikin A. Wahab ◽  
...  

AbstractWernicke’s encephalopathy (WE) is a rare life-threatening complication following severe hyperemesis gravidarum. Early recognition of this condition and prompt thiamine administration is the key to preventing devastating sequelae. We report a successful delivery of a small-for-gestational-age (SGA) baby by a patient with WE and thyrotoxicosis in pregnancy.


Author(s):  
Ana Caeiro ◽  
Irina Ramilo ◽  
Ana Santos ◽  
Elizabeth Ferreira ◽  
Isabel Batalha

AbstractAmniotic fluid embolism (AFE) is a rare but potentially catastrophic clinical condition, characterized by a combination of signs and symptoms that reflect respiratory distress, cardiovascular collapse and disseminated intravascular coagulation (DIC). Its pathogenesis is still unclear. More recently, the traditional view of obstruction of pulmonary capillary vessels by amniotic fluid emboli as the main explanation for the etiology has been ruled out, and immunologic factors and the activation of the inflammatory cascade took on an important role. Amniotic fluid embolism has an unpredictable character, its diagnosis is exclusively clinical, and the treatment consists mainly of cardiovascular support and administration of blood products to correct the DIC. No diagnostic test is recommended until now, though multiple blood markers are currently being studied. The authors present a case report of a woman who had survived AFE in her previous pregnancy and had a subsequent pregnancy without recurrence, providing one more clinical testimony of the low risks for the pregnancy after AFE.


Author(s):  
Wang X ◽  
◽  
Qi H ◽  

Amniotic Fluid Embolism (AFE) as a devastating complication in obstetrics remains one leading causes of maternal mortality in developed country. During the process of resuscitation, there are some vital deficiencies which mainly involve neglect of high risk factors, delayed recognition of early signs and symptoms, poor knowledge about emergency resuscitation, invalid of management of heart failure, coagulopathy and multi-organ failure. This mini review mainly presented correlative high risk factors, early recognition initial signs or symptoms, and effective therapeutic measures including medicine selection of vasopressors and inotropes, application of Mechanical Circulatory Support (MCS), management of consumptive coagulation, and maintenance of homeostasis.


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