scholarly journals Utility of urinary calcium/creatinine ratio in evaluation of urinary stone formers: a Sudanese case control study

2016 ◽  
Vol 5 (1) ◽  
pp. 146
Author(s):  
Awad Elkarim Hassan Abdallah ◽  
Abuobieda Bala Abusharib ◽  
Abdulhadi Mohamed Elbashir ◽  
Ihab Hamed Nourien
Keyword(s):  
Case Control Study ◽  
Stone Formation ◽  
Urinary Stone ◽  
Case Control ◽  
Urinary Calcium ◽  
Creatinine Ratio ◽  
Evaluation Tool ◽  
Mean Values ◽  
Stone Formers ◽  
Control Study

Background: Hypercalciuria is a common cause of urinary stone formation in both children and adults; one of the components of the comprehensive evaluation of stone formers is to measure 24 hours urinary calcium, which is a complicated method especially in children, therefore some physicians depend on calcium creatinine ratio instead of it. The objective of this study was to assess the utility of calcium/creatinine ratio as an evaluation tool for hypercalciuria in urinary stone formers.Methods: This was a case control study in which forty patients of urinary stone formers along with fifteen healthy controls group were enrolled; after fulfilling specific inclusion and exclusion criteria a questionnaire was filled, then an early morning urinary samples were collected for calcium and creatinine measurement to calculate the calcium creatinine ratio.Results: The results showed significantly higher mean value of calcium/creatinine ratio in the stone formers group compared with controls one. Also there were statistically insignificant differences in the urinary calcium between the two groups. Moreover this study showed higher mean values of both calcium and calcium/creatinine ratio in recurrent stone formers when compared with first time stone former.Conclusions: This study concluded that calcium/creatinine ratio is a useful and easier method for the initial evaluation of stone formers.

Nutrition and urinary calcium stone formation in northwestern India: a case control study

1996 ◽  
Vol 24 (3) ◽  
pp. 141-147 ◽  
Author(s):  
Rajkiran ◽  
A. K. Pendse ◽  
R. Ghosh ◽  
D. V. S. S. Ramavataram ◽  
P. P. Singh
Keyword(s):  
Case Control Study ◽  
Stone Formation ◽  
Case Control ◽  
Urinary Calcium ◽  
Calcium Stone ◽  
Northwestern India ◽  
Control Study

scholarly journals Is urinary excretion of plasminogen associated with development of pre-eclampsia? An observational, explorative case–control study

BMJ Open ◽  
2019 ◽  
Vol 9 (6) ◽  
pp. e026489 ◽  
Author(s):  
Lise H Nielsen ◽  
Camilla Kronborg ◽  
Erik Vittinghus ◽  
Gitte Kitlen ◽  
Boye L Jensen ◽  
...  
Keyword(s):  
Urinary Excretion ◽  
Pregnant Women ◽  
Sodium Excretion ◽  
Case Control Study ◽  
Case Control ◽  
Secondary Outcome ◽  
Creatinine Ratio ◽  
Albumin Creatinine Ratio ◽  
Gestational Week ◽  
Control Study

ObjectivesPre-eclampsia (PE) is characterised by renal glomerular endotheliosis and injury to the glomerular filtration barrier with proteinuria. Patients with PE display aberrant filtration of the plasma proenzyme plasminogen which is activated, in the tubular fluid, to plasmin. Plasmin may activate the epithelial sodium channel and cause impaired sodium excretion and contribute to hypertension. An explorative study was conducted to test the association between urinary total plasminogen/plasmin and the development of PE. A positive association was hypothesised.DesignAn observational, explorative, nested case–control study of healthy pregnant women.SettingsA Danish County hospital. Samples were collected between 2001 and 2004.Participants1631 healthy pregnant women participated. Urine samples were collected longitudinally six times during pregnancy. 30 developed PE (cases) and were compared with 146 randomly selected healthy pregnant women (controls).Primary outcomeThe association between total plasminogen/plasmin excreted in the urine and PE development is expressed by ORs. Total urinary excretion of plasminogen/plasmin was defined by the urine plasminogen-plasmin/creatinine ratio.Secondary outcomeThe association between urine (u)-albumin/creatinine ratio, u-aldosterone/creatinine ratio and PE development is expressed by ORs. The correlation between urinary (u-) plasmin and u-aldosterone concentration is expressed as a correlation coefficient.ResultsThe development of PE in late pregnancy was associated with increased levels of the urine plasminogen-plasmin/creatinine ratio (OR=2.35; 95% CI: 1.12 to 4.93; p<0.05).U-aldosterone/creatinine ratio did not predict PE at any time. U-albumin/creatinine ratio was positively associated with the development of PE from gestational week 33 (OR=14.04; 95% CI: 2.56 to 76.97; p<0.01) and in week 33–35 (OR=14.15; 95% CI: 3.44 to 58.09; p<0.001) and after gestational week 36, respectively.ConclusionAberrant filtration of plasminogen may contribute to the pathophysiological features of impaired sodium excretion and hypertension associated with PE late in pregnancy. However, increased urinary albumin levels reveal stronger associations with PE development compared with urinary plasminogen levels.

E19 Urinary risk factors for brushite stone formation: A case-control study

2011 ◽  
Vol 10 (7) ◽  
pp. 466
Author(s):  
R. Siener ◽  
L. Netzer ◽  
C. Fisang ◽  
A. Hesse
Keyword(s):  
Risk Factors ◽  
Case Control Study ◽  
Stone Formation ◽  
Case Control ◽  
Control Study

scholarly journals Characteristics of Dietary Habits in Renal Stone Formers. Case Control Study.

1991 ◽  
Vol 44 (3) ◽  
pp. 163-169 ◽  
Author(s):  
Masanori IGUCHI ◽  
Tohru UMEKAWA ◽  
Chisato TAKAMURA ◽  
Yasuaki ISHIKAWA ◽  
Yoshikazu KATAYAMA ◽  
...  
Keyword(s):  
Renal Stone ◽  
Case Control Study ◽  
Dietary Habits ◽  
Case Control ◽  
Stone Formers ◽  
Control Study

scholarly journals Determinants of Brushite Stone Formation: A Case-Control Study

PLoS ONE ◽  
2013 ◽  
Vol 8 (11) ◽  
pp. e78996 ◽  
Author(s):  
Roswitha Siener ◽  
Linda Netzer ◽  
Albrecht Hesse
Keyword(s):  
Case Control Study ◽  
Stone Formation ◽  
Case Control ◽  
Control Study

scholarly journals Diabetes mellitus as a Potential Risk Factor for Renal Disease among Nepalese: A Hospital Based Case Control Study

1970 ◽  
Vol 1 (1) ◽  
pp. 22-25
Author(s):  
Ankush Mittal ◽  
Brijesh Sathian ◽  
Arun Kumar ◽  
Nishida Chandrasekharan ◽  
Aditya Sunka
Keyword(s):  
Diabetes Mellitus ◽  
Kidney Disease ◽  
Renal Disease ◽  
Case Control Study ◽  
Case Control ◽  
Mean Values ◽  
Developing Kidney ◽  
Stage Renal Disease ◽  
End Stage ◽  
Control Study

BackgroundDiabetes mellitus is a well recognized public health concern and projections of its future effect are alarming.  It is one of the leading causes of end stage renal disease in both developed and emerging nations. The objective of the present study was to assess the progressive deterioration of renal function in Diabetes mellitus among Nepalese.Materials and Methods  It was a hospital based case control study carried out in the Department of Biochemistry of Manipal Teaching Hospital, Pokhara, Nepal between 1st January 2010 and 31st August 2010. The variables collected were age, gender, random blood glucose, serum urea and creatinine levels of the patients. ResultsOut of 440 patients, there was a slight predominance of males (54.1%) as compared to females (45.8%). Patients in between 41-100 years were 2.8 times more at risk of developing kidney disease as compared to age group (0-40 years)(Odds Ratio=2.8, p=0.0001). Diabetic patients were twice at risk of developing kidney disease than non diabetics (Odds Ratio=1.97, p=0.001). There was a significant increase in mean values of serum creatinine (CI 4.3 to 4.8) and urea (CI 118.55 to 153.50) in kidney disease patients with Diabetes mellitus. In non diabetic kidney disease patients, mean values of serum creatinine (CI 3.29 to 3.70) and urea (CI 98.88 to 116.92) were also moderately raised as compared to controls.ConclusionDiabetic renal lesions are not only preventable but also reversible. In summary, glycemic control significantly influences the rate of progression from microalbuminuria to proteinuria and from overt nephropathy to end stage renal disease. The best modality of treatment includes strict control over blood glucose levels and its evaluation at frequent intervals.Key Words: Diabetic Mellitus; Kidney Disease; Case Control Study; NepalDOI: 10.3126/nje.v1i1.4108Nepal Journal of Epidemiology 2010;1 (1):22-25

scholarly journals Trabeculectomy with Healaflow versus Trabeculectomy for the Treatment of Glaucoma: A Case-Control Study

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Dimitris Papaconstantinou ◽  
Andreas Diagourtas ◽  
Petros Petrou ◽  
Alexandros Rouvas ◽  
Athanasios Vergados ◽  
...  
Keyword(s):  
Case Control Study ◽  
Group Versus ◽  
Study Groups ◽  
Case Control ◽  
Control Group ◽  
Study Group ◽  
Safe Procedure ◽  
Mean Values ◽  
Control Study

Purpose. To compare the outcomes of trabeculectomy with and without Healaflow (Anteis S.A, Geneva, Switzerland), a high molecular weight viscoelastic gel, in patients requiring glaucoma surgery.Methods. This was a retrospective, comparative, interventional case-control study. Forty patients formed two matched study groups and were analyzed (trabeculectomy alone (control) versus trabeculectomy with Healaflow (study)).Results. The postoperative levels of mean IOP were statistically significantly lowerP<0.05than preoperatively in both groups, for all time intervals. There was no statistical difference, at the end of the follow-up period, between the two groups in the mean values of the IOP (14.9 ± 3.2 mmHg for the study group versus 14.8 ± 3.3 mmHg for the control group). The number of antiglaucoma drugs used in the study group was reduced from a preoperative mean of 3.4 ± 0.75 to a 6-month postoperative mean of 0.6 ± 0.8P<0.001and in the control group from 3.6 ± 0.59 to 0.55 ± 0.9P<0.001.Conclusions. Although trabeculectomy with Healaflow appears to be a safe procedure, we failed to identify any significant advantages in the use of Healaflow when compared with trabeculectomy alone, at the end of the 6-month follow-up period.

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