scholarly journals Discoid lupus erythematosus with epithelial dysplasia: a case report

2017 ◽  
Vol 5 (6) ◽  
pp. 2833
Author(s):  
Harishchandra Rai ◽  
Anitha Dayakar ◽  
Supriya H. ◽  
Elizabeth Sojan
Keyword(s):  
Lupus Erythematosus ◽  
World Literature ◽  
Rare Case ◽  
Connective Tissue Diseases ◽  
Epithelial Dysplasia ◽  
World Health ◽  
Discoid Lupus Erythematosus ◽  
The World ◽  
Malignant Changes ◽  
Health Organization

Lupus erythematosus is a classic example of an immunologically mediated condition and is one of the most common of the so called “collagen vascular” or connective tissue diseases. Lupus erythematosus was first described by Biett in 1828 and Kaposi in 1872. Development of squamous cell carcinoma (SCC) can occur in DLE, with about 20 cases reported in the world literature to-date, which led the World Health Organization (WHO) to classify DLE as one of the precancerous conditions. Thus malignant changes in such a condition must be given utmost importance. This article focuses on a rare case of DLE with epithelial dysplasia.

scholarly journals Vulvar Tuberculosis—A Rare Manifestation of the Disease

2019 ◽  
Vol 41 (09) ◽  
pp. 575-578 ◽  
Author(s):  
Cristina Bragança ◽  
Inês Gonçalves ◽  
Luísa Guerreiro ◽  
Maria Janeiro
Keyword(s):  
Rare Case ◽  
Causes Of Death ◽  
World Health ◽  
Histological Findings ◽  
Chain Reaction ◽  
Rare Manifestation ◽  
The World ◽  
History Of ◽  
Polymerase Chain ◽  
Health Organization

AbstractTuberculosis is an infectious disease caused by Mycobacterium tuberculosis. According to data from the World Health Organization, this disease remains one of the leading causes of death worldwide. Although it most commonly affects the lungs, tuberculosis can compromise any organ. The present study reports a rare case of vulvar tuberculosis in a postmenopausal woman with a history of asymptomatic pulmonary and pleural tuberculosis, with no prior documented contact with the bacillus. Diagnosis was based on vulvar lesion biopsies, with histological findings suggestive of infection and isolation of M. tuberculosis by microbiological culture and polymerase chain reaction (PCR) essays. The lesions reverted to normal after tuberculostatic therapy.

scholarly journals Paraganglioma of the cauda equina – Case Report and Literature Review

2022 ◽  
Author(s):  
Arthur Araújo Massoud Salame ◽  
Bernardo de Andrada Pereira ◽  
Lygia Sampaio de Arruda Camara ◽  
Iogo Henrique de Oliveira Araújo ◽  
Filipe Moreira de Almeida Pinheiro ◽  
...  
Keyword(s):  
World Literature ◽  
Cauda Equina ◽  
Immunohistochemical Analysis ◽  
World Health ◽  
Benign Lesions ◽  
Spine Tumor ◽  
The World ◽  
Microsurgical Resection ◽  
Hypertensive Crises ◽  
Health Organization

AbstractParagangliomas of the cauda equina are tumors of rare incidence, with ∼ 220 cases described in the world literature. They are benign lesions, grade I by the World Health Organization (WHO), whose definitive diagnosis can only be made by immunohistochemical analysis. Its neuroendocrine nature is evidenced by the presence of chromogranin. The relevance of reporting this case is because paragangliomas of the cauda equina should be included among the differential diagnoses of intradural and extramedullary tumors, and especially because they can cause perioperative and intraoperative hypertensive crises by adrenergic discharge.The present study presents the case of a 36-year-old male patient diagnosed with a lumbar spine tumor located in the central spinal canal that presented as cauda equina syndrome involving 4 months of bilateral sciatica, paraparesis, urinary and fecal retention. The diagnosis of paraganglioma was confirmed by immunohistochemical positivity for chromogranin after microsurgical resection of the tumor.

Primary low-grade myofibroblastic sarcoma: A rare case report of this tumor in the orbit and literature review

2020 ◽  
pp. 112067212097039
Author(s):  
Lijuan Tang ◽  
Hua Xu ◽  
Huanhuan Gao ◽  
Huasheng Yang ◽  
Shuxia Chen ◽  
...  
Keyword(s):  
Case Report ◽  
Rare Case ◽  
World Health ◽  
Low Grade ◽  
Distinct Entity ◽  
Myofibroblastic Sarcoma ◽  
The World ◽  
Rare Case Report ◽  
Health Organization ◽  
Myofibroblastic Differentiation

Low-grade myofibroblastic sarcoma (LGMS) is an exceedingly rare, malignant tumor with myofibroblastic differentiation. It frequently occurs in the oral cavity and extremities, despite being classified as a distinct entity by the World Health Organization (WHO). Here, we report a rare case of orbital LGMS occurring in an 11-month-old baby with a 3.2 × 2.4 × 2.1 cm mass. LGMS was diagnosed based on the histological and immunohistochemical findings. Previous literature suggests that surgical resection with clear margins is an appropriate method for the treatment of LGMS, and combined adjuvant therapy (local radiotherapy with or without chemotherapy) can improve the prognosis, but further studies are needed.

scholarly journals A rare presentation of an ACTH-producing high grade large cell neuroendocrine carcinoma with Cushing's syndrome

2021 ◽  
Author(s):  
Francis Essien ◽  
Christine Persaud ◽  
David Dado ◽  
Joshua Tate ◽  
George Shahin
Keyword(s):  
Neuroendocrine Carcinoma ◽  
Rare Case ◽  
Large Cell ◽  
Large Cell Neuroendocrine Carcinoma ◽  
World Health ◽  
High Grade ◽  
Rare Tumor ◽  
Rare Presentation ◽  
The World ◽  
Health Organization

Large cell neuroendocrine carcinoma (LCNEC) was first proposed by Travis et al. in 1991 and subsequently classified as high grade neuroendocrine carcinoma (HGNEC) by the world health organization. It is a rare tumor with unclear clinicopathologic features. Herein, we describe a rare case of LCNEC with a unique Cushing’s presentation.

scholarly journals Dhat Syndrome: A Review of the World Literature

2016 ◽  
Vol 3 (3) ◽  
Author(s):  
Altaf Ahmad Malla ◽  
Nasir Mohammad Bhat
Keyword(s):  
World Literature ◽  
Classification Systems ◽  
World Health ◽  
Geographical Regions ◽  
The World ◽  
The Status ◽  
Classification Of Diseases ◽  
Icd 10 ◽  
International Statistical Classification ◽  
Health Organization

Dhat syndrome is described as a culture bound syndrome (CBS). There is an ongoing debate on the nosological status of CBS. Dhat syndrome has been found to be prevalent in different geographical regions of the world. It has been described in literature from China, Europe, Americas, and Russia at different points of time in history. Mention of semen as a “soul substance” could be found in the works of Galen and Aristotle who have explained the physical and psychological features associated with its loss. However, the current classification systems such as International Statistical Classification of Diseases and Related Health Conditions‑10 (ICD‑10) (World Health Organization (WHO)) and Diagnostic and Statistical Manual (DSM)‑IV‑TR (American Psychiatric Association) do not give guidelines to diagnose these culture‑bound conditions in the main text. The revisions of these two most commonly used nosological systems (the ICD and DSM) are due in near future. The status of this condition in these upcoming revisions is likely to have important implications. The article reviews the existing literature on dhat syndrome.

Basal cell carcinoma arising over lesion of discoid lupus erythematosus: a rare occurrence

Lupus ◽  
2019 ◽  
Vol 29 (2) ◽  
pp. 210-212
Author(s):  
P Pradhan ◽  
S Samal ◽  
M Sable
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Lupus Erythematosus ◽  
Rare Case ◽  
Discoid Lupus Erythematosus ◽  
Incisional Biopsy ◽  
Rare Occurrence ◽  
Cold Knife ◽  
Malignant Changes

Although the association of discoid lupus erythematosus (DLE) with squamous cell carcinoma has been described in the literature, coexistence with a basal cell carcinoma is very rare. The indolent and non-pruritic nature of the lesion cause it often to be diagnosed at the late stage of the disease. Long-standing photosensitivity and chronic inflammation later lead to scarring and hypopigmentation, which are considered as the risk factors for the malignant changes over DLE. Incisional biopsy is often performed from the erythematosus lesion which does not respond to medical treatment. Here we have reported a rare case of basal cell carcinoma of the skin developing in the background of long-standing DLE, which was successfully managed with cold knife local excision.

Disguised ulcer of lip and buccal mucosa – rare clinical manifestation of tuberculosis: a case report

2012 ◽  
Vol 8 (3) ◽  
Author(s):  
Reddy Sudhakara Reddy ◽  
Dr. K. Ramya ◽  
Manyam Ravi Kanth ◽  
Uddarraju Shivaji Raju
Keyword(s):  
Oral Cavity ◽  
Rare Case ◽  
World Health ◽  
Oral Manifestations ◽  
Granulomatous Disease ◽  
Oral Ulcers ◽  
The World ◽  
Health Organization ◽  
Systemic Health

Introduction: Oral tuberculosis is a chronic granulomatous disease caused by Mycobacterium tuberculosis. According to the World Health Organization (WHO), nearly 2 billion people are infected with tuberculosis. Objective: To report a rare case of oral tuberculosis with ulcers at two different sites. Materials and methods: In order to emphasize the need to consider tuberculosis in the differential diagnosis of non-healing ulcers of oral cavity and the role of oral physician in preventing the spread of such lesions, this article presents a case of oral ulcers at two different sites, diagnosed as tuberculosis ulcer. Results: Oral cavity, which is considered to be a mirror of systemic health, rarely manifests tuberculosis. With increasing number of tuberculosis cases and unusual form of the disease in the oral cavity, the cases are likely to be misdiagnosed. Conclusion: An oral clinician should have a thorough knowledge of tuberculosis and its oral manifestations.

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