scholarly journals Common causes and trends of hepatocellular carcinoma at regional cancer centre Raipur, India

2018 ◽  
Vol 7 (1) ◽  
pp. 85
Author(s):  
Pradeep K. Chandrakar ◽  
Vivek Choudhary ◽  
Surendra K. Azad ◽  
Manjula Beck
Keyword(s):  
Hepatocellular Carcinoma ◽  
Alcohol Consumption ◽  
Urban Areas ◽  
Asia Pacific ◽  
Asia Pacific Region ◽  
Hospital Data ◽  
Primary Malignancy ◽  
Common Causes ◽  
The Common ◽  
Regional Cancer Centre

Background: Hepatocellular Carcinoma (HCC) is the most common primary malignancy of the liver and is the third most common cause of cancer related deaths in Asia-pacific region. Representative data on epidemiology of HCC in India is scanty and mostly from urban areas. It is more common in males then female. Hepatitis, alcohol consumption, aflatoxin and other hepatotoxins in diet are common causes. Authors did a study for the common causes and trends of the HCC registered at authors’ centre between January 2013 to November 2018.Methods: Authors analyzed their hospital data for the patient registered with the diagnosis of hepatocellular carcinoma at their centre during the study period for age, sex, number and causes.Results: Out of 23,766 patients registered for cancer in study period, 132 (0.55%) patients were of HCC, of which 89 (66.4%) were males and 43 (32.6%) were females, with ratio of 2:1. Commonest age group was between 50-59 years 46 (34.6%) followed by 40-49years 26 (19.5%). No patients were below 20 years of age. Among the commonest causes were alcohol consumption in 71 (53.4%), hepatitis B in 37 (27.8%), hepatitis C in 10 (7.5%), HIV in 4 (3%) and unknown in 11 (8.3%). There is rising trend in males and declining trend in females.Conclusions: Incidence of hepatocellular carcinoma is low among all cancer but has high mortality rate. Alcohol consumption and hepatitis were the commonest cause. It is common above 40 years specially in males.

Restricting alcohol consumption to reduce liver disease in the Asia-Pacific region

2020 ◽  
Vol 5 (2) ◽  
pp. 105-107
Author(s):  
Heng Jiang ◽  
Robin Room ◽  
Orratai Waleewong ◽  
Wei Hao
Keyword(s):  
Liver Disease ◽  
Alcohol Consumption ◽  
Asia Pacific ◽  
Pacific Region ◽  
Asia Pacific Region

scholarly journals Hepatocellular carcinoma in the Asia pacific region

2009 ◽  
Vol 24 (3) ◽  
pp. 346-353 ◽  
Author(s):  
Man-Fung Yuen ◽  
Jin-Lin Hou ◽  
Anuchit Chutaputti
Keyword(s):  
Hepatocellular Carcinoma ◽  
Asia Pacific ◽  
Pacific Region ◽  
Asia Pacific Region

Financial Fragility and Crisis Union in the Asia-Pacific Region

2009 ◽  
Vol 9 (2) ◽  
pp. 1850165 ◽  
Author(s):  
Frank Strobel
Keyword(s):  
Financial Crisis ◽  
Decision Problem ◽  
Asia Pacific ◽  
Financial Fragility ◽  
Pacific Region ◽  
Asia Pacific Region ◽  
Financial Systems ◽  
The Common ◽  
Common Perception

We examine whether core ASEAN+3 countries might be interested in joining a financial "crisis union," allowing for the role of uncertainty by constructing a stylized real options model of the decision problem involved. We calibrate that model by proxying financial fragility with commonly used bank asset ratios and observe that, according to our criteria, a wider financial crisis union might be more attainable the more encompassing that grouping is; however, our results also reinforce the common perception of pervasive, possibly prohibitive, heterogeneity in these countries' banking and financial systems.

The New Arbitration Ordinance of the Hong Kong Special Administrative Region

2012 ◽  
Vol 51 (1) ◽  
pp. 133-197
Author(s):  
Lee Tin Yan
Keyword(s):  
Hong Kong ◽  
Dispute Resolution ◽  
Common Law ◽  
Asia Pacific ◽  
Pacific Region ◽  
Special Administrative Region ◽  
Legal Environment ◽  
Asia Pacific Region ◽  
Administrative Region ◽  
The Common

Because of the unique position that Hong Kong occupies in China and its separate legal system based on the common law, it is a well-established policy of the Hong Kong Special Administrative Region (‘‘HKSAR’’) Government to develop and enhance Hong Kong’s status as a major dispute resolution centre in the Asia Pacific region. One significant initiative in this regard is the recent introduction of a new Arbitration Ordinance to further improve the legal environment for arbitration in Hong Kong.

scholarly journals Evolving Treatment of Advanced Hepatocellular Carcinoma in the Asia–Pacific Region: A Review and Multidisciplinary Expert Opinion

Cancers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 2626
Author(s):  
Sadahisa Ogasawara ◽  
Su-Pin Choo ◽  
Jiang-Tao Li ◽  
Changhoon Yoo ◽  
Bruce Wang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Expert Opinion ◽  
Kinase Inhibitors ◽  
Asia Pacific ◽  
Advanced Hepatocellular Carcinoma ◽  
Pacific Region ◽  
Patient Access ◽  
Asia Pacific Region ◽  
First Line ◽  
Systemic Treatments

Hepatocellular carcinoma (HCC) is the fourth most common driver of cancer-related death globally, with an estimated 72% of cases in Asia. For more than a decade, first-line systemic treatments for advanced or unresectable HCC were limited to the multi-targeted kinase inhibitors sorafenib and, more recently, lenvatinib. Now, treatment options have expanded to include immunotherapy, as exemplified by the immune checkpoint inhibitor (ICI) atezolizumab combined with the antiangiogenic agent bevacizumab. Additional combinations of ICIs with kinase inhibitors, other ICIs, or antiangiogenic agents are under investigation, further supporting the new era of immunotherapy for first-line treatment of advanced or unresectable HCC. We describe this evolving landscape and provide expert opinion on therapeutic best practices in the Asia–Pacific region, where different costs of, and patient access to, treatment are a challenge. With the combination of atezolizumab plus bevacizumab likely to become the clinical standard of care, optimising treatment sequence and ensuring patient access to newer therapies remain priorities. Cost containment and treatment sequencing may be facilitated by characterisation of predictive positive and negative biomarkers. With these considerations in mind, this review and expert opinion focused on advanced HCC in the Asia–Pacific region offers perspectives of multiple stakeholders, including physicians, payer systems, and patients.

scholarly journals A Review Article on Toxicity Induced Hepatocellular Carcinoma: Through Gara Visa perspective

2021 ◽  
Vol 6 (4) ◽  
pp. 222-224
Author(s):  
S Mayoori ◽  
◽  
CK Krishnan Nair ◽  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Food Habits ◽  
Environmental Toxicity ◽  
Drug Induced ◽  
Primary Malignancy ◽  
Dramatic Rise ◽  
The Common ◽  
Sedentary Life ◽  
Sedentary Life Style ◽  
Treatment Aspect

Hepatocellular carcinoma is the most common primary malignancy of liver in adults and is the common cause of death in people with cirrhosis [1] . The majority of this disease occurs over pre-existing chronic liver cirrhosis but the increased changes in living conditions, food habits and sedentary life style has emerged the disease into a silent killer category independent of cirrhosis. The present modifications in food habits, drug induced toxicity and other environmental toxicity has led to a dramatic rise in HCC even in non-alcoholics. The symptoms and pathogenesis in HCC can be eventually be correlated with Garavisa Lakshana, Samprapthi and the judicious application of its treatment in Ayurveda can concrete a new path in its treatment aspect.

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