scholarly journals Role of robotic arm assistance in computed tomography guided bone biopsy

2019 ◽  
Vol 7 (6) ◽  
pp. 2127
Author(s):  
Natasha N. Mehta ◽  
Nikit Mehta ◽  
Nitin Gorde
Keyword(s):  
Image Guidance ◽  
Bone Biopsy ◽  
Robotic Arm ◽  
Bone Lesions ◽  
Practical Skills ◽  
Ct Guided ◽  
Nerve Structure ◽  
Metastatic Lesions ◽  
Technological Developments

Background: Use of robotic assistance technique has significant benefits over conventional techniques. The present study looks at the recent technological developments in image guidance for bone biopsy procedures.Methods: Patients who were referred to the department of radiodiagnosis, Bharti Hospital and Dot3d scanning center, Sangli, Maharashtra, India from July 2017 till December 2018 with suspected bone lesions were included in the study. These patients underwent robotic arm CT guided bone biopsy of their lesions.Results: In the present study, 47 patients were included. Authors observed that 93.6% had a positive diagnosis based on CT guided bone biopsy. Metastatic lesions were diagnosed in 8 cases. Inflammatory lesions and tuberculosis were other commonly observed diagnosis.Conclusions: Further growth and development of medical imaging devices have allowed more interventional procedures to be performed and more patients to benefit from them. Radiologists needs to develop a thorough understanding of the anatomical structure involved and need to acquire both solid grounding in technology and the practical skills to visualize a nerve structure.

scholarly journals Differences in Radiation Exposure of CT-Guided Percutaneous Manual and Powered Drill Bone Biopsy

2021 ◽  
Author(s):  
Sebastian Zensen ◽  
Sumitha Selvaretnam ◽  
Marcel Opitz ◽  
Denise Bos ◽  
Johannes Haubold ◽  
...  
Keyword(s):  
Radiation Exposure ◽  
Diagnostic Yield ◽  
Bone Biopsy ◽  
Lumbar Vertebrae ◽  
Bone Lesions ◽  
Anatomical Location ◽  
Thoracic Vertebrae ◽  
Level Of Evidence ◽  
Ct Guided ◽  
Bone Biopsies

Abstract Purpose Apart from the commonly applied manual needle biopsy, CT-guided percutaneous biopsies of bone lesions can be performed with battery-powered drill biopsy systems. Due to assumably different radiation doses and procedural durations, the aim of this study is to examine radiation exposure and establish local diagnostic reference levels (DRLs) of CT-guided bone biopsies of different anatomical regions. Methods In this retrospective study, dose data of 187 patients who underwent CT-guided bone biopsy with a manual or powered drill biopsy system performed at one of three different multi-slice CT were analyzed. Between January 2012 and November 2019, a total of 27 femur (A), 74 ilium (B), 27 sacrum (C), 28 thoracic vertebrae (D) and 31 lumbar vertebrae (E) biopsies were included. Radiation exposure was reported for volume-weighted CT dose index (CTDIvol) and dose–length product (DLP). Results CTDIvol and DLP of manual versus powered drill biopsy were (median, IQR): A: 56.9(41.4–128.5)/66.7(37.6–76.2)mGy, 410(203–683)/303(128–403)mGy·cm, B: 83.5(62.1–128.5)/59.4(46.2–79.8)mGy, 489(322–472)/400(329–695)mGy·cm, C: 97.5(71.6–149.2)/63.1(49.1–83.7)mGy, 627(496–740)/404(316–515)mGy·cm, D: 67.0(40.3–86.6)/39.7(29.9–89.0)mGy, 392(267–596)/207(166–402)mGy·cm and E: 100.1(66.5–162.6)/62.5(48.0–90.0)mGy, 521(385–619)/315(240–452)mGy·cm. Radiation exposure with powered drill was significantly lower for ilium and sacrum, while procedural duration was not increased for any anatomical location. Local DRLs could be depicted as follows (CTDIvol/DLP): A: 91 mGy/522 mGy·cm, B: 90 mGy/530 mGy·cm, C: 116 mGy/740 mGy·cm, D: 87 mGy/578 mGy·cm and E: 115 mGy/546 mGy·cm. The diagnostic yield was 82.4% for manual and 89.4% for powered drill biopsies. Conclusion Use of powered drill bone biopsy systems for CT-guided percutaneous bone biopsies can significantly reduce the radiation burden compared to manual biopsy for specific anatomical locations such as ilium and sacrum and does not increase radiation dose or procedural duration for any of the investigated locations. Level of Evidence Level 3.

Basics of Computed Tomography

2016 ◽  
Author(s):  
Krikor Malajikian ◽  
Daniel Finelli
Keyword(s):  
Computed Tomography ◽  
Soft Tissues ◽  
Imaging Modality ◽  
Bone Biopsy ◽  
Bone Lesions ◽  
Disc Space ◽  
Ct Guided ◽  
Ct Arthrography ◽  
Facet Injections ◽  
Joint Injections

Computed tomography (CT)-guidance is typically used when precise needle placement is essential for a successful procedure. It uses ionizing radiation, which could pose risks to the patient and operating staff if proper technique is not used. The performing physician should adhere to all principles of minimizing radiation exposure to the patient and clinicians. Common CT-guided imaging procedures include facet injections, nerve root injections, sacroiliac joint injections, intradiscal procedures, vertebroplasty/sacroplasty, and image-guided ablation of painful bone lesions. Computed tomography is also the imaging modality of choice for aspiration of deep paraspinal soft tissues in addition to disc space or bone biopsy in acute discitis/osteomyelitis. In fluoroscopic-guided knee or shoulder joint injections, CT arthrography is a useful adjunct to better assess anatomy when MRI is contraindicated. When imaging the postoperative spine, CT myelography has some advantages over MRI, and CT is also superior to MRI in assessing par intra-articularis defects or spondylolysis.

scholarly journals PET/CT-guided versus CT-guided percutaneous core biopsies in the diagnosis of bone tumors and tumor-like lesions: which is the better choice?

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Min-hao Wu ◽  
Ling-fei Xiao ◽  
Huo-wen Liu ◽  
Zhi-qiang Yang ◽  
Xiao-xiao Liang ◽  
...  
Keyword(s):  
Bone Tumors ◽  
Diagnostic Performance ◽  
Bone Biopsy ◽  
Chinese Patients ◽  
Bone Lesions ◽  
Ct Guided ◽  
Tumor Dissemination ◽  
Pet Ct ◽  
Significant Difference ◽  
Tumor Like Lesions

Abstract Objective The present study aimed to evaluate the diagnostic performance and safety of PET/CT-guided percutaneous core bone biopsy and to compare the PET/CT-guided method to conventional CT-guided percutaneous core biopsies to diagnose Chinese patients with bone tumors and tumor-like lesions. Methods Data for 97 patients with bone tumors and tumor-like lesions diagnosed by percutaneous core bone biopsy from February 2013 to November 2018 were retrospectively analyzed. The study included 42 cases in the PET/CT group and 55 cases in the CT alone group. The diagnostic performance, cost and complications associated with the intervention were compared between the two groups. All patients were eventually confirmed to have bone tumors and tumor-like lesions according to surgical pathology findings. Results There were no significant differences in patient characteristics (P > 0.05). For the patients in the PET/CT group, the overall diagnostic yield of the initial biopsies and the diagnostic accuracy derived from the surgically proven cases were both 97.62%, which was significantly higher than the values in the CT group during the same period (P < 0.05). No major biopsy-related complications (e.g., serious bleeding or tumor dissemination) occurred before, during, or after the intervention. Therefore, no significant difference was observed between the two groups with regard to the complication rate (P > 0.05). Conclusion Compared with CT-guided percutaneous bone biopsy, PET/CT-guided percutaneous bone biopsy is an effective and safe alternative with high diagnostic performance in the evaluation of hypermetabolic bone lesions to diagnose bone tumors and tumor-like lesions.

Technical Feasibility of Electromagnetic US/CT Fusion Imaging and Virtual Navigation in the Guidance of Spine Biopsies

2020 ◽  
Author(s):  
Giovanni Mauri ◽  
Salvatore Gitto ◽  
Lorenzo Carlo Pescatori ◽  
Domenico Albano ◽  
Carmelo Messina ◽  
...  
Keyword(s):  
Intervertebral Disc ◽  
Bone Biopsy ◽  
Fusion Imaging ◽  
Bone Lesions ◽  
Technical Feasibility ◽  
Ct Guided ◽  
Spinal Lesions ◽  
Procedure Duration ◽  
Group 2 ◽  
Group 1

Abstract Purpose To test the technical feasibility of electromagnetic computed tomography (CT) + ultrasound fusion (US)-guided bone biopsy of spinal lesions. Materials and Methods This retrospective study included 14 patients referred for biopsy of spinal bone lesions without cortical disruption or intervertebral disc infection. Lesions were located in the sacrum (n = 4), lumbar vertebral body (n = 7) or intervertebral disc (n = 3). Fusion technology matched a pre-procedure CT scan with real-time ultrasound. The first six procedures were performed under both standard CT and CT + US fusion guidance (group 1). In the last eight procedures, the needle was positioned under fusion imaging guidance alone, and CT was only used at the end of needle placement to confirm correct positioning (group 2). Additionally, we retrieved 8 patients (controls) with location-matched lesions as group 2, which were biopsied in the past with the standard CT-guided technique. The procedure duration and number of CT passes were recorded. Results Mean procedure duration and median CT pass number were significantly higher in group 1 vs. group 2 (45 ± 5 vs. 26 ± 3 minutes, p = 0.002 and 7; 5.25–8.75 vs. 3; 3–3.25, p = 0.001). In controls, the mean procedure duration was 47 ± 4 minutes (p = 0.001 vs. group 2; p = 0.696 vs. group 1) and the number of CT passes was 6.5 (5–8) (p = 0.001 vs. group 2; p = 0.427 vs. group 1). No complications occurred and all specimens were adequate overall. In one case in group 2, the needle position was modified according to CT assessment before specimen withdrawal. Conclusion Electromagnetic CT+US fusion-guided bone biopsy of spinal lesions is feasible and safe. Compared to conventional CT guidance, it may reduce procedural time and the number of CT passes.

scholarly journals Computed tomography-guided bone lesion biopsy, our experience in 2018 and 2019

2020 ◽  
Vol 48 (2-3) ◽  
pp. 73-76
Author(s):  
Elvira Krešić ◽  
◽  
Ana-Marija Alduk ◽  
Maja Prutki ◽  
Ivan Karlak ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Histological Analysis ◽  
Bone Lesion ◽  
Bone Lesions ◽  
Histopathological Analysis ◽  
Ct Guided ◽  
Metastatic Lesions ◽  
Ct Guided Biopsy ◽  
Procedural Complications ◽  
Histopathological Results

To present our results from 2018 and 2019 and to present the clinical data of the accuracy and clinical usefulness of computed tomography (CT)-guided biopsy for diagnosing suspicious bone lesion. The retrospective study included 98 consecutive patients who underwent CT-guided bone lesion biopsy from January 2018 to December 2019. The localization of the bone lesions, the adequacy of the sample for histopathological analysis, histopathological results, and the procedure’s complications were analyzed. The specimens collected from 76 patients/lesions (77.6%) were considered appropriate for diagnosis. Histological analysis of bone samples showed 52 (68.4%) metastatic lesions. The most common primary tumor origins were breast carcinoma 28 (53.8%) and lung carcinoma six (11.5%). In three patients (4%), the infection was confirmed. No tumor cells were found in 17 (22.4%) patients. There were no post-procedural complications. CT-guided bone lesion biopsy is a safe and effective method for diagnosing suspicious bone lesions that has a great effect in clinical practice without any significant complications.

The Effect of Information Technology on Fluidity of Contemporary Architectural Space

2019 ◽  
Vol 7 (1) ◽  
pp. 62-72
Author(s):  
Shatha Abbas Hassan ◽  
Noor Ali Aljorani
Keyword(s):  
Information Technology ◽  
Communication Systems ◽  
Research Problem ◽  
Architectural Space ◽  
Human Thought ◽  
Technological Developments ◽  
Ease Of Access ◽  
The Impact ◽  
Role Of Information

The increasing importance of the information revolution and terms such as ‘speed’, ‘disorientation’, and ‘changing the concept of distance’, has provided us with tools that had not been previously available. Technological developments are moving toward Fluidity, which was previously unknown and cannot be understood through modern tools. With acceleration of the rhythm in the age we live in and the clarity of the role of information technology in our lives, as also the ease of access to information, has helped us to overcome many difficulties. Technology in all its forms has had a clear impact on all areas of daily life, and it has a clear impact on human thought in general, and the architectural space in particular, where the architecture moves from narrow spaces and is limited to new spaces known as the ‘breadth’, and forms of unlimited and stability to spaces characterized with fluidity. The research problem (the lack of clarity of knowledge about the impact of vast information flow associated with the technology of the age in the occurrence of liquidity in contemporary architectural space) is presented here. The research aims at defining fluidity and clarifying the effect of information technology on the changing characteristics of architectural space from solidity to fluidity. The research follows the analytical approach in tracking the concept of fluidity in physics and sociology to define this concept and then to explain the effect of Information Technology (IT) to achieve the fluidity of contemporary architectural space, leading to an analysis of the Skidmore, Owings and Merrill (SOM) architectural model. The research concludes that information technology achieves fluidity through various tools (communication systems, computers, automation, and artificial intelligence). It has changed the characteristics of contemporary architectural space and made it behave like an organism, through using smart material.

scholarly journals CT-guided bone biopsy using electron density maps from dual-energy CT

2021 ◽  
Vol 16 (9) ◽  
pp. 2343-2346
Author(s):  
Shota Yamamoto ◽  
Shunsuke Kamei ◽  
Kosuke Tomita ◽  
Chikara Fujita ◽  
Kazuyuki Endo ◽  
...  
Keyword(s):  
Electron Density ◽  
Bone Biopsy ◽  
Dual Energy ◽  
Dual Energy Ct ◽  
Ct Guided ◽  
Density Maps

scholarly journals Needle placement accuracy in CT-guided robotic post mortem biopsy

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Martin Gromniak ◽  
Maximilian Neidhardt ◽  
Axel Heinemann ◽  
Klaus Püschel ◽  
Alexander Schlaefer
Keyword(s):  
Needle Biopsy ◽  
Minimal Invasive ◽  
Robotic Arm ◽  
Limited Time ◽  
Time Since Death ◽  
Time Cost ◽  
Needle Placement ◽  
Manner Of Death ◽  
Ct Guided ◽  
Placement Accuracy

AbstractForensic autopsies include a thorough examination of the corpse to detect the source or alleged manner of death as well as to estimate the time since death. However, a full autopsy may be not feasible due to limited time, cost or ethical objections by relatives. Hence, we propose an automated minimal invasive needle biopsy system with a robotic arm, which does not require any online calibrations during a procedure. The proposed system can be easily integrated into the workflow of a forensic biopsy since the robot can be flexibly positioned relative to the corpse. With our proposed system, we performed needle insertions into wax phantoms and livers of two corpses and achieved an accuracy of 4.34 ± 1.27 mm and 10.81 ± 4.44 mm respectively.

scholarly journals Validity of negative bone biopsy in suspicious bone lesions

2021 ◽  
Vol 10 (7) ◽  
pp. 205846012110306
Author(s):  
Mine B Lange ◽  
Lars J Petersen ◽  
Michael B Nielsen ◽  
Helle D Zacho
Keyword(s):  
Bone Biopsy ◽  
False Negative ◽  
Exclusion Criterion ◽  
Bone Lesions ◽  
False Negatives ◽  
Patient Morbidity ◽  
Bone Biopsies ◽  
Initial Biopsy ◽  
Valid Criterion

Background The presence of malignant cells in bone biopsies is considered gold standard to verify occurrence of cancer, whereas a negative bone biopsy can represent a false negative, with a risk of increasing patient morbidity and mortality and creating misleading conclusions in cancer research. However, a paucity of literature documents the validity of negative bone biopsy as an exclusion criterion for the presence of skeletal malignancies. Purpose To investigate the validity of a negative bone biopsy in bone lesions suspicious of malignancy. Material and Method A retrospective cohort of 215 consecutive targeted non-malignant skeletal biopsies from 207 patients (43% women, 57% men, median age 64, and range 94) representing suspicious focal bone lesions, collected from January 1, 2011, to July 31, 2013, was followed over a 2-year period to examine any additional biopsy, imaging, and clinical follow-up information to categorize the original biopsy as truly benign, malignant, or equivocal. Standard deviations and 95% confidence intervals were calculated. Results 210 of 215 biopsies (98%; 95% CI 0.94–0.99) showed to be truly benign 2 years after initial biopsy. Two biopsies were false negatives (1%; 95% CI 0.001–0.03), and three were equivocal (lack of imaging description). Conclusion Our study documents negative bone biopsy as a valid criterion for the absence of bone metastasis. Since only 28% had a confirmed diagnosis of prior cancer and not all patients received adequately sensitive imaging, our results might not be applicable to all cancer patients with suspicious bone lesions.

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