scholarly journals Correlation of serum magnesium levels with renal parameters in patients with acute kidney injury

2020 ◽  
Vol 8 (10) ◽  
pp. 3698
Author(s):  
Raveendra K. R. ◽  
Avinash H. R. ◽  
Nitish Ashok Gurav
Keyword(s):  
Diabetes Mellitus ◽  
Acute Kidney Injury ◽  
Obstructive Uropathy ◽  
Serum Magnesium ◽  
Kidney Injury ◽  
Drug Induced ◽  
Cross Sectional ◽  
Electrolyte Disturbance ◽  
Electrolyte Disturbances ◽  
Patients With Diabetes

Background: Acute kidney injury is a common problem with various causes and consequences like electrolyte disturbances in the form of hypocalcaemia, hypokalemia, hyperkalemia depending on the phase. Hypomagnesaemia is one of the most common electrolyte disturbance found in hospitalized patients especially in the critically ill patients. Prevalence of hypomagnesemia varies from 11 to 65% in different studies. Hence, we decided to conduct a study to evaluate correlation of serum magnesium levels in AKI.Methods: A cross-sectional, hospital based time bound study was conducted between November 2016 and August 2018 with a sample of 100 patients aged 18-65 years and who had AKI were included and patients with diabetes mellitus, multi-organ dysfunction, obstructive uropathy and drug induced AKI were excluded from study. The decrease in magnesium <1.7 mg/L was defined as hypomagnesaemia. AKI was defined as per AKIN criteria. Day 1, day 3 and day 6 magnesium levels were measured.Results: Prevalence of hypomagnesaemia was 53%, 30% and 36% on day 1, day 3 and day 6 respectively. It was observed that there was a positive correlation between serum magnesium, and serum creatinine. Normomagnsemia and hypermagnesemia on day 1, 3 and 6 were significantly associated with recovery of AKI (p<0.001).Conclusions: The prevalence of hypomagnesemia was significantly higher in AKI patients and normal magnesium and hypermagnesium on day 1, 3 and day 6 was associated with recovery than non-recovery. Hypomagnesemia was associated more with non-recovery then recovery.

scholarly journals The impact of diabetes on outcomes, length of stay and costs in acute kidney injury patients: a cross-sectional multicenter study in China

2020 ◽  
Author(s):  
Lishan Tan ◽  
Li Chen ◽  
Lingyan Li ◽  
Jinwei Wang ◽  
Xiaoyan Huang ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Length Of Stay ◽  
Hospital Mortality ◽  
Hospital Stay ◽  
Kidney Injury ◽  
Renal Recovery ◽  
Cross Sectional ◽  
Patients With Diabetes ◽  
The Impact ◽  
Physician Diagnosis

Abstract Background : With the increasing worldwide prevalence and disease burden of diabetic mellitus, data on the impact of diabetes on acute kidney injury (AKI) patients in China are limited.Methods: A nationwide cross-sectional and retrospective study was conducted in China, which included 2,223,230 hospitalized adult patients and covered 82% of the country’s population. Diabetes was identified according to blood glucose, hemoglobin A1c levels, physician diagnosis and drug use. In total, 7604 AKI patients were identified, and 1404 and 6200 cases were defined as diabetic and non-diabetic respectively. Clinical characteristics, outcome, in-hospital stay, and costs of AKI patients with and without diabetes were compared. Multivariable logistic and linear regression analyses were conducted to evaluate the association of diabetes with mortality and renal recovery in the admitted AKI patients.Results: In this survey, AKI patients with diabetes were older, male-dominated (61.9%), with more comorbidities, and higher serum creatinine levels. Compared to patients without diabetes, a significant upswing in all-cause in-hospital mortality, hospital stay, and costs were found in those with diabetes ( p <0.05). After adjusted for relevant covariables, diabetes was independently associated with failed renal recovery (OR=1.13, p =0.04), rather than all-cause in-hospital mortality (OR=1.09, p =0.39). Also, diabetic status was positively associated with length of stay ( β =0.04, p =0.04) and costs ( β =0.09, p <0.01) in hospital after adjusted for possible confounders. Conclusions: Failed renal recovery, rather than all-cause in-hospital mortality, is independently associated with diabetes in hospitalized AKI patients. Moreover, diabetes is significantly correlated with in-hospital stay and expenditures in AKI.

scholarly journals Drug-Induced Hospital-Acquired Acute Kidney Injury in China: A Multicenter Cross-Sectional Survey

2020 ◽  
pp. 1-13
Author(s):  
Chen Liu ◽  
Suying Yan ◽  
Yuqin Wang ◽  
Jinwei Wang ◽  
Xiujuan Fu ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Kidney Injury ◽  
Cross Sectional Survey ◽  
Drug Induced ◽  
Cross Sectional ◽  
Hospital Acquired

Drug-Induced Acute Kidney Injury in China: A Multicenter Cross-Sectional Survey

2019 ◽  
Author(s):  
Chen Liu ◽  
Suying Yan ◽  
Jinwei Wang ◽  
Xiujuan Fu ◽  
Hongtao Song ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Kidney Injury ◽  
Cross Sectional Survey ◽  
Drug Induced ◽  
Cross Sectional

scholarly journals Outcome of Acute Kidney Injury in Patients with Type 2 Diabetes Mellitus

2017 ◽  
Vol 6 (2) ◽  
pp. 95-99
Author(s):  
Sarwar Iqbal ◽  
Wasim Md Mohosinul Haque ◽  
Tufayel Ahmed Chowdhury ◽  
Mehruba Alam Ananna ◽  
Muhammad Abdur Rahim ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Acute Gastroenteritis ◽  
Renal Damage ◽  
Obstructive Uropathy ◽  
Rapidly Progressive Glomerulonephritis ◽  
Kidney Injury ◽  
Cross Sectional Study ◽  
Diabetic Patients ◽  
Cross Sectional ◽  
Diabetic Population

Background: Diabetic patients are more vulnerable to develop acute kidney injury (AKI) when compared to non diabetic counterpart. However, it is not known whether outcome of AKI is variable according to etiology in diabetic subjects. This study was aimed to observe the causes of AKI in diabetic population and to evaluate the outcome.Methods: This cross-sectional study was done in Department of Nephrology, BIRDEM General Hospital, from May 2009 to April 2010. During the study period a total of 50 subjects were included. All cases of AKI and AKI on chronic kidney disease (CKD) were included except AKI due to trauma.Results: AKI due to acute gastroenteritis, non-steroidal anti-inflammatory drugs (NSAIDs),septicemia, gentamicin, obstructive uropathy, rapidly progressive glomerulonephritis (RPGN) comprised 46%, 42%, 4%, 2%,2%, and 4% cases respectively. All cases of AKI due to acute gastroenteritis improved. Among NSAID induced AKI, 26% improved, 6% improved with residual renal damage, 8% did not improve and 1% patient expired. All cases of septicemia induced AKI improved. Patient with gentamicin induced AKI improved with residual renal damage. Patient with obstructive uropathy improved. None of AKI cases due to RPGN improved.Conclusion: It may be suggested that outcome of AKI is variable according to etiology. Outcome is better in AKI due to pre-renal and post-renal causes than AKI due to intrinsic causes. Further study can be done to compare the outcome of AKI according to etiology between diabetic and non-diabetic populations.Birdem Med J 2016; 6(2): 95-99

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