scholarly journals The state of dyslipidemia after laparoscopic sleeve gastrectomy

2018 ◽  
Vol 5 (7) ◽  
pp. 2392
Author(s):  
Ahmed Mahmoud Hussein
Keyword(s):  
Sleeve Gastrectomy ◽  
Laparoscopic Sleeve Gastrectomy ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
The Body ◽  
P Value ◽  
Morbidly Obese ◽  
Successful Operation ◽  
Restrictive Procedure ◽  
The Mean

Background: Obesity and dyslipidemia have a strong relation to the development of cardiovascular diseases. Bariatric surgery is directed towards the loss of patients weight and resolution of comorbidities as hyperlipidemia. Laparoscopic sleeve gastrectomy, a feasible restrictive procedure, is one the most popular and successful operations for achieving this purpose. The aim of present study was to evaluate the effect of laparoscopic sleeve gastrectomy on the lipid profile, comparing preoperative with postoperative results 12 months after surgery.Methods: This study included fifty morbidly obese cases that underwent laparoscopic sleeve gastrectomy (LSG). Preoperative and postoperative BMI and lipid parameters were documented and analysed at 12 months postoperatively.Results: The mean age of the studied group ±SD was 32.7±9.2 years, female predominance was found. BMI improved significantly after the LSG procedure with a mean±SD of 32.2±4 kg/m2. A significant improvement of dyslipidemia was found with a p-value (<0.001) regarding the mean level±SD of total cholesterol (TC) (180.5±25mg/dl), triglycerides (TG) (127.2±14.7mg/dl), low density lipoprotein (LDL) (94.2±14.5mg/dl) and high density lipoprotein (HDL) (48.4±5.6 mg/dl).Conclusions: Laparoscopic sleeve gastrectomy is a feasible and successful operation in reducing the body weight and subsequently improving the dyslipidemia of the morbid obese individuals.

scholarly journals The Effect of Laparoscopic Sleeve Gastrectomy on Obstructive Sleep Apnea Syndrome

2018 ◽  
Author(s):  
Tuğrul Çakır ◽  
Hülya Eyigör ◽  
Arif Aslaner ◽  
Nurullah Bülbüller ◽  
Mehmet Tahir Oruç ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleeve Gastrectomy ◽  
Sleep Apnea ◽  
Laparoscopic Sleeve Gastrectomy ◽  
Morbidly Obese ◽  
Safe Procedure ◽  
Obese Patients ◽  
Obstructive Sleep ◽  
Severely Obese ◽  
The Mean

Background: The repeated episode of obstructive hypopnea and apnea during sleep is defined as obstructive sleep apnea (OSA) and it is a common condition in obese patients. Studies performing bariatric surgery have demonstrated a significant improvement in OSA by weight reduction. In this prospective study we aimed to explore the efficacy and safety of Laparoscopic Sleeve Gastrectomy (LSG) on OSAS among severely obese patients. Material and Methods: A total of 32 morbidly obese patients who underwent LSG for morbid obesity were included in this study. Body weight, height, body mass index (BMI) and standard overnight polysomnography (PSG) were measured at before and after LSG at the 6th month. &nbsp;Results: 32 patients (27 female, 5 male) who have postoperative PSG's were included in this study. The mean age was 43.22&plusmn;9.87 years old. The mean preoperative and postoperative BMIs were 50.36&plusmn;8.14kg/m&sup2; and 37.27&plusmn;7.93kg/m&sup2;, respectively. The mean Epworth sleepiness scale determined as 5.84&plusmn;4.65 preoperatively and 2.19&plusmn;3.55 postoperatively. The preoperative and postoperative sleep efficiency test of the patients was determined as 83.34&plusmn;9.68 and 88.94&plusmn;6.90 respectively. AHI average at the preoperative PSG was 31.47&plusmn;26.34, while 9.35&plusmn;10:34 at postoperative 6 months and found as statistically significant. Conclusion: Our data showed that LSG is an efficient and safe procedure on severely obese patients and showed a predictive remission of clinical and sleep parameters of patients with OSA by analyzing PSG data during the first 6 months.

scholarly journals Optical Coherence Tomography Parameters in Morbidly Obese Patients Who Underwent Laparoscopic Sleeve Gastrectomy

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Berna Dogan ◽  
Ugur Dogan ◽  
Muhammet Kazim Erol ◽  
Mani Habibi ◽  
Nurullah Bulbuller
Keyword(s):  
Optical Coherence Tomography ◽  
Sleeve Gastrectomy ◽  
Laparoscopic Sleeve Gastrectomy ◽  
Morbidly Obese ◽  
Optical Coherence ◽  
Obese Patients ◽  
Fiber Layer ◽  
Deep Imaging ◽  
Disc Area ◽  
The Mean

Purpose. To investigate changes in optical coherence tomography parameters in morbidly obese patients who had undergone laparoscopic sleeve gastrectomy (LSG).Methods. A total of 41 eyes of 41 morbidly obese patients (BMI ≥ 40) who had undergone LSG were included in study. The topographic optic disc parameters, central macular thickness (CMT), total macular volume (TMV), and retinal ganglion cell layer (RGCL) were measured by spectral-domain optical coherence tomography (SD-OCT). Subfoveal choroidal thickness (SFCT) was measured by enhanced deep imaging-optical coherence tomography (EDI-OCT).Results. The mean CMT was237.4±24.5 μm,239.3±24.1 μm, and240.4±24.5 μm preoperatively, 3 months postoperatively, and 6 months postoperatively, respectively (p<0.01). The mean TMV was9.88±0.52 mm3,9.96±0.56 mm3, and9.99±0.56 mm3preoperatively, 3 months postoperatively, and 6 months postoperatively, respectively (p<0.01). The mean RGCL was81.2±6.5 μm,82.7±6.6 μm, and82.9±6.5 μm preoperatively, 3 months postoperatively, and 6 months postoperatively, respectively (p<0.01). The mean SFCT was309.8±71.8 μm,331.0±81.4 μm, and352.7±81.4 μm preoperatively, 3 months postoperatively, and 6 months postoperatively, respectively (p<0.01). No statistically significant differences were found between the preoperative values and 3- and 6-month postoperative values in rim area (p=0.34), disc area (p=0.64), vertical cup/disc ratio (p=0.39), cup volume (p=0.08), or retinal nerve fiber layer (p=0.90).Conclusions. Morbidly obese patients who undergo LSG experience a statistically significant increase in CMT, TMV, SFCT, and RGCL at 3 months and 6 months after surgery.

scholarly journals GAMBARAN KADAR KOLESTEROL LOW DENSITY LIPOPROTEIN (LDL) PADA MASYARAKAT PEROKOK DI PESISIR PANTAI

2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Aji M. Sanhia ◽  
Damajanty H. C. Pangemanan ◽  
Joice N. A. Engka
Keyword(s):  
Ldl Cholesterol ◽  
Descriptive Analysis ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
The Body ◽  
Low Density ◽  
Cross Sectional ◽  
The Mean ◽  
Cross Sectional Design

Abstract: Low Density Lipoprotein (LDL) is a type of lipoprotein that transports cholesterol most widely in the body. Smoking is one of the factors that can cause elevated levels of LDL cholesterol, which nicotine is one element in cigarettes cathecolamine that stimulates secretion, increases lipolysis, and also increases free fatty acids. Excessive levels of LDL cholesterol in the blood will increase the risk of cholesterol buildup in the arteries, followed by atherosclerosis. This study aimed to describe the levels of LDL cholesterol in seashores community smoker. This was a descriptive analysis with a cross sectional design. Samples in this study were 40 people. The results showed that the mean LDL cholesterol level of 40 samples was 132.93 mg / dl which 24 sample (60%) was at the above the borderline threshold. There was no subject with high LDL level. Conclusion: There was an increase in LDL level in smokers who lived in seashores.Keywords: low density lipoprotein (LDL), smokers.Abstrak: Low Density Lipoprotein (LDL) merupakan jenis lipoprotein yang paling banyak mengangkut kolesterol di dalam tubuh. Merokok merupakan salah satu faktor yang dapat menyebabkan terjadinya peningkatan kadar kolesterol LDL, dimana nikotin yang merupakan salah satu unsur pada rokok merangsang sekresi katakolamin, meningkatkan lipolisis, dan meningkatkan asam lemak bebas. Kadar kolesterol LDL yang berlebihan dalam darah akan meningkatkan resiko penumpukan kolesterol pada dinding pembuluh darah arteri yang diikuti dengan terjadinya aterosklerosis. Penelitian ini bertujuan untuk mengetahui gambaran kadar kolesterol LDL pada masyarakat di pesisir pantai. Penelitian yang digunakan bersifat deskriptif analisis dengan rancangan Cross Sectional Study. Sampel dalam penelitian ini berjumlah 40 orang yang sesuai kriteria inklusi dan bersedia menjadi responden. Hasil penelitian memperlihatkan tingkat kolesterol LDL rata-rata pada 40 sampel ialah 132,93 mg/dl, dengan 24 sampel (60%) berada di atas ambang batas dan sisanya memiliki kadar LDL di bawah ambang batas. Simpulan: Terdapat peningkatan kadar LDL pada perokok yang tinggal di pesisir pantai.Kata kunci: low density lipoprotein (LDL), perokok.

scholarly journals Lipid Profile as a Nutritional Status Marker in Tuberculosis

2020 ◽  
Author(s):  
Vaishnavi Sandip Salunkhe ◽  
Vinayak Wamanrao Patil ◽  
Pooja Rai
Keyword(s):  
Nutritional Status ◽  
Lipid Profile ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
The Body ◽  
Lipoprotein Cholesterol ◽  
P Value ◽  
Low Density ◽  
Low Density Lipoprotein Cholesterol ◽  
Pulmonary Tb

Introduction: Tuberculosis (TB) is a global health problem. India has the highest cases in the world and accounts for nearly one fifth of global cases. TB is a chronic disease and in long term leads to malnutrition. Lipids are important constituents in the body that determine the nutritional status and immune function. Aim: To study lipid profile as a nutritional status marker in pulmonary TB. Materials and Methods: Fifty patients of pulmonary TB and fifty healthy subjects in age group of 18-60 years were included for study. The lipid profile was analysed to assess the nutritional status of the patients. Unpaired t-test was used to study the significance of study parameters in cases and controls group. The p-value of <0.05 was considered to be statistically significant. Results: Out of 100 subjects 63% were males 37% were females. Significant decreased levels of total cholesterol, Triglycerides, High Density Lipoprotein-Cholesterol (HDL), Very Low Density Lipoprotein-Cholesterol (VLDL), Low Density Lipoprotein-Cholesterol (LDL) were seen in cases as compared to controls. Conclusion: In this study, it was observed that lipid profile could play a significant role as a biochemical marker of nutritional status in pulmonary TB patients. Thus, knowledge of these levels can help in providing a proper balanced diet to these patients which can ultimately help in better quality treatment.

A multicenter prospective hospital-based cohort study on the efficacy and safety of pitavastatin.

2020 ◽  
Vol 17 ◽  
Author(s):  
Abdullah Shehab ◽  
Asim Ahmed Elnour ◽  
Akshaya Srikanth Bhagavathula ◽  
Joseph Pulavelil Kurian ◽  
Gazi Hassan ◽  
...  
Keyword(s):  
Cohort Study ◽  
Adverse Events ◽  
United Arab Emirates ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Low Density ◽  
Efficacy And Safety ◽  
Onset Diabetes ◽  
The Mean ◽  
New Onset

Aims: We aim to investigate the efficacy and safety of pitavastatin 4 mg in a population of people living in the United Arab Emirates (UAE). Background: Pitavastatin is a member of the HMG-CoA reductase inhibitors family which was approved for use in adult subjects with primary hyperlipidemia or mixed dyslipidemia. To date, no published studies have assessed the efficacy and safety of pitavastatin in the United Arab Emirates. Objective: The main objective of the current study was to investigate the efficacy and safety of pitavastatin in subjects with dyslipidemia for primary prevention of cardiovascular diseases based on total cardiovascular risk. Methods: This was a multicentre (four private hospitals) prospective cohort study to analyze data on the use of pitavastatin for dyslipidemia in adult outpatients in Abu Dhabi and Dubai emirates, United Arab Emirates. We have followed-up the clinical profiles of subjects in four hospitals for six-weeks during the period from June 2015 to June 2017. Efficacy was based on the evaluation of the mean (± standard deviation) change in low-density lipoprotein cholesterol between baseline and week six after the initiation of pitavastatin therapy. Safety was reported as the incidence of adverse events occurred with the use of pitavastatin and the development of new-onset diabetes. Results: A total of 400 subjects who were receiving pitavastatin 4 mg were included. The mean age of subjects was 50.7 ±10.8 years, of these 79.0% were males. At the baseline, the mean level of total cholesterol was 185.4 ±41.5 mg/dL, low density lipoprotein was 154.9 ±48.55 mg/dL, high-density lipoprotein cholesterol was 40.5 ±11.23 mg/dL and fasting blood glucose was 115.0 (±16.63) mg/dl. At the end of six weeks, low density lipoprotein levels significantly decreased to 112.09 ±41.90 mg/dl (standard mean difference [SMD] (-42.8%), 95% CI: -42.88 [-49.17 to -36.58] mg/dl, P <0.001), while high density lipoprotein levels improved (SMD, 95% CI: 1.77% [0.25 to 3.28] mg/dl, P <0.022). There were 55 subjects (13.7%) reported various adverse events such as myalgia (7.5%), sleep disorders (2.5%), and myopathy (2.2%). Furthermore, 4 (1.0%) have had developed new-onset diabetes post six-weeks of initiation of pitavastatin therapy. Conclusion: Pitavastatin 4 mg had howed robust efficacy in reducing LDL-C levels and improving HDL-C levels in subjects with dyslipidemias. The use of pitavastatin was associated with a low discontinuation rate, fewer adverse events, and very limited cases of new-onset diabetes.

scholarly journals Daily Time Use by Activity of Community-Dwelling Older Koreans: Focus on Health Management

2021 ◽  
Vol 18 (4) ◽  
pp. 1688
Author(s):  
Hana Ko
Keyword(s):  
Older Adults ◽  
Time Use ◽  
Health Management ◽  
Subjective Evaluation ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Community Dwelling ◽  
Senior Center ◽  
The Mean ◽  
Daily Time

This study aimed to examine the daily time use by activity and identified factors related to health management time (HMT) use among 195 older adults (mean age = 77.5, SD = 6.28 years; 70.8% women) attending a Korean senior center. Descriptive statistics were analyzed and gamma regression analyses were performed. Participants used the most time on rest, followed by leisure, health management, daily living activities, and work. The mean duration of HMT was 205.38 min/day. The mean score for the subjective evaluation of health management (SEHM) was 13.62 and the importance score for SEHM was 4.72. Factors influencing HMT included exercise, number of chronic conditions, fasting blood sugar level, low density lipoprotein level, and cognitive function. HMT and frailty significantly predicted SEHM. HMT interventions focus on promoting exercise and acquiring health information to improve health outcomes among older adults in senior centers.

scholarly journals One-year outcome of laparoscopic sleeve gastrectomy in morbidly obese adolescents

2021 ◽  
Vol 17 (1) ◽  
Author(s):  
Mohamed El ghazeery ◽  
Mohamed Elsawaf ◽  
Mohamed Ashour ◽  
Mohamed Metwaly ◽  
Mohamed Hashish
Keyword(s):  
Sleeve Gastrectomy ◽  
Laparoscopic Sleeve Gastrectomy ◽  
Fatty Infiltration ◽  
Adolescent Obesity ◽  
Morbidly Obese ◽  
Safe Procedure ◽  
Short Term ◽  
Obese Adolescents ◽  
Important Health ◽  
One Year

Abstract Background Adolescent obesity is an important health issue. Non-surgical weight management programs, even the most aggressive, have shown modest weight reduction results. Laparoscopic sleeve gastrectomy (LSG) is gaining reliability as a low surgical risk bariatric procedure with proper efficiency for this age group. The aim of this study was to present our initial experience with LSG in morbidly obese adolescents and to report short-term clinical and metabolic outcome. Results Mean age was 16.43 years, and mean preoperative weight and body mass index (BMI) were 132.68 kg and 48.90 respectively. Mean excess weight loss (EWL) was 54.11 kg 1 year after LSG, corresponding to 74 EWL% as well as mean BMI loss (BML) of 19.89. LSG improved fatty infiltration of the liver in 75% of cases and other comorbidities in 100% of patients. Conclusions LSG proved to be a safe procedure with significant short-term clinical and metabolic success for adolescent obesity.

scholarly journals Extremely elevated lipoprotein (a) as an independent risk factor for peripheral arterial disease in large patient cohort

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
M.R Poudel ◽  
S Kirana ◽  
D Stoyanova ◽  
K.P Mellwig ◽  
D Hinse ◽  
...  
Keyword(s):  
Peripheral Arterial Disease ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Arterial Disease ◽  
P Value ◽  
Lipoprotein A ◽  
Large Patient ◽  
Increased Risk ◽  
Revascularization Therapy ◽  
Peripheral Arterial

Abstract Background Elevated lipoprotein (a) [LP (a)] levels are an independent, genetic, and causal factor for cardiovascular disease and associated with myocardial infarction (MI). Although the association between circulating levels of lipoprotein(a) [Lp(a)] and risk of coronary artery disease (CAD) is well established, its role in risk of peripheral arterial disease (PAD) remains unclear. PAD affects over 236 million individuals and follows ischaemic heart disease (IHD) and cerebrovascular disease (CVD) as the third leading cause of atherosclerotic cardiovascular morbidity worldwide. LP (a) is genetically determined, stable throughout life and yet refractory to drug therapy. While 30 mg/dl is considered the upper normal value for LP (a) in central Europe, extremely high LP (a) levels (&gt;150mg/dl) are rare in the general population. The aim of our study was to analyse the correlation between lipoprotein (a) [LP (a)] levels and an incidence of PAD in high-risk patients. Patients and methods We reviewed the LP (a) concentrations of 52.898 consecutive patients admitted to our cardiovascular center between January 2004 and December 2014. Of these, 579 patients had LP (a) levels above 150 mg/dl (mean 181.45±33.1mg/dl). In the control collective LP (a) was &lt;30mg/dl (n=350). Other atherogenic risk factors in this group were HbA1c 6.58±1.65%, low density lipoprotein (LDL) 141.99±43.76 mg/dl, and body mass index 27.81±5.61. 54.40% were male, 26.07% were smokers, 93.2% had hypertension, and 24% had a family history of cardiovascular diseases. More than 82.6% were under statins. The mean glomerular filtration rate (GFR) was 69.13±24.8 ml/min [MDRD (Modification of Diet in Renal Disease)]. Results 45.00% (n=261) of the patients with LP (a) &gt;150mg/dl had PAD. The prevalence of PAD in patients with LP (a) &lt;30mg/dl in our control collective was 15.8%. (P- Value 0.001). Patients with LP (a) &gt;150mg/dl had a significantly increased risk for PAD (Odds ratio 4.36, 95% CI 2.94–6.72, p: 0.001). 19.1% of patients were re-vascularized by percutaneous angioplasty (PTA) and 7.09% of patients had to undergo peripheral vascular bypass (PVB). Mean LP (a) level in patients with PAD was 182.6±31.61. Conclusion Elevated LP (a) levels above 150 mg/dl are associated with a significantly increased risk of PAD in our collective and it confirms our hypothesis. Over one fourth of these patients had severe PAD and requiring revascularization therapy. We need more prospective studies to confirm our findings. Funding Acknowledgement Type of funding source: None

Gastric Stenosis After Laparoscopic Sleeve Gastrectomy in Morbidly Obese Patients

2013 ◽  
Vol 23 (9) ◽  
pp. 1481-1486 ◽  
Author(s):  
Ana María Burgos ◽  
Attila Csendes ◽  
Italo Braghetto
Keyword(s):  
Sleeve Gastrectomy ◽  
Laparoscopic Sleeve Gastrectomy ◽  
Morbidly Obese ◽  
Obese Patients ◽  
Gastric Stenosis
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