scholarly journals A study of effectiveness of topical insulin on healing of diabetic ulcers at tertiary health care centre: a cross sectional study from Puducherry

2020 ◽  
Vol 7 (3) ◽  
pp. 857
Author(s):  
Paritoshsingh B. Thakur ◽  
T. Ramachandrudu ◽  
Anant A. Takalkar

Background: Insulin being a growth factor was proved to stimulate angiogenesis, collagen formation, matrix formation and granulation tissue proliferation in several preclinical studies. The objective was to study effectiveness of topical insulin on healing of diabetic ulcers at tertiary health care centre.Methods: This was a cross sectional study carried out in the Department of surgery of a tertiary health care centre during August 2018 to August 2019 so during this period there were 60 patients. Group A was given topical insulin application. Group B was given saline application. The statistical analysis was done by using SPSS 24.0 version and un-paired t-test and chi-square tests are applied as test of significance.Results: Average time required for granulation tissue to appear (mean±SD) was significantly less in group A as compared to Group B (p<0.001, df=58, t=5.87); Average surface area of wound (mm2) at day 6th day was significantly less in group A (p<0.05, df=58,t=3.98); average depth of the wounds (mm) at day 6th day was significantly less in Group A as compared to in Group B (p<0.001, df=58, t=4.92).Conclusions: The topical application of insulin is significantly associated with fastening of wound healing in the diabetic ulcer.

Author(s):  
Sushama S. Thakre ◽  
Subhash B. Thakre ◽  
Priti N. Tiwari ◽  
Hitesh C. Tayade

Background: Breastfeeding is the most important intervention for reducing infant mortality and ensuring normal growth and development of a child. Objective of this study was to assess the knowledge, attitude, and practices toward Breastfeeding among lactating mothers visiting immune-prophylaxis clinic of tertiary health care centre, Nagpur Maharashtra.Methods: A hospital-based cross-sectional study was conducted among 400 mothers at tertiary health care centre, Nagpur in the state of Maharashtra, India. The lactating mothers whose children under the age of 3 years were interviewed.Results: Maximum number of women were in the age group of 26-30 years (46%). Mothers with parity >1 had satisfactory knowledge regarding breastfeeding (p=0.0001). Prevalence of exclusive breastfeeding rate was found to be 86%.Conclusions: Efforts should be strengthened to make mothers aware of health benefits of breastfeeding for themselves and their offspring to improve the overall maternal and child health.


2019 ◽  
Vol 19 (1) ◽  
pp. 124
Author(s):  
Vinay Bannur ◽  
Prasanna S. Jirli ◽  
Ravindra S. Honnungar ◽  
Vishal V. Koulapur ◽  
Somashekhar S. Pujar

2021 ◽  
Vol 17 (37) ◽  
pp. 270-292
Author(s):  
Foziah Jabbar ALSHAMRANI ◽  
Noor Mohammad ALMOHISH ◽  
Mohammed Faisal ALMUAIGEL ◽  
Narjes Ali ALRAMADHAN ◽  
Maryam Mohammad ALJUMAH

Background: Primary headache is one of the most common disorders treated in neurology clinics. Globally, it has been estimated that the current prevalence of headache disorder in adults symptomatic, at least once within the last year, is about 50%. According to the Global Burden of Disease Study 2015, migraine was ranked as the third most common cause of disability worldwide. One of the significant migraines is migraine with aura, a frequent headache that occurs after or with sensory disturbances. Aim: This study aimed to identify and compare triggers in previously diagnosed patients with migraine with aura (MwA) to those who have not been identified with migraine with aura before but diagnosed according to a questionnaire survey distributed in the Kingdom of Saudi Arabia (KSA). Methods: Adults aged 18–50 years were randomly selected in the Kingdom of Saudi Arabia to participate in this non-interventional, multicentre, cross-sectional study. The study data was collected via an online questionnaire using the diagnostic criteria of the International Classification of Headache Disorders 2018 and the Cleveland Clinic Canada headache questionnaire. Results and Discussion: Of the 4.140 potentially eligible individuals, 302 were not previously diagnosed with migraine with aura but were diagnosed with a questionnaire (Group A), while 71 participants were already diagnosed (MwA) (Group B). A significant relationship was found among MwA and stress and anxiety, sleep disturbance, noisy places, exposure to lots of lights, prolonged computer work, hunger, fasting, studying for exams, and menstruation in Group A. Group B experienced all of the previous triggers in addition to weather changes, certain odors, and the consumption of cheese, bananas, and hotdogs. Conclusions: The trigger factors are common in individuals with MwA. Awareness of these triggers is essential for preventing the severe complications of MwA, hence, enhance the quality of life of patients.


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