scholarly journals Quality of life assessment in patients who have undergone oncologic resection of rectum: a retrospective, three arms, single centre, observational study

2020 ◽  
Vol 7 (7) ◽  
pp. 2169
Author(s):  
Quresh Bambora ◽  
Mangesh Shingade ◽  
Mamta Sankhla ◽  
Atul Rajpara

Background: Quality of life (QOL) analysis following cancer surgery is a sensitive issue among patients. The present study tried to find the status of these QOL parameters in patients who had undergone oncogenic resection of rectum.Methods: Patients were given the short form 36 (SF-36), The European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30 and the EORTC QLQ-C29 questionnaires to fill at three time points in their treatment (prior to surgery, 3 months and 6 months following surgery). The prospectively collected questionnaires were analysed retrospectively.Results: On comparing SF-36 questionnaire, there was significant improvement as we proceeded from baseline to first and second visit except for the energy level. On EORTC-30 questionnaire, there was significant improvement in all scales as we proceeded from baseline to first visit and then to second visit. On comparing EORTC-29 questionnaire, among all visits of abdominoperineal resection (APR), symptoms like pain and blood or mucus in stools significantly improved, low anterior resection (LAR) showed significant improvement in all 4 scales, high anterior resection (HAR) patients showed worst micturition complaints during first visit and gradually improving scores for other scales from baseline to first and second visit.Conclusions: The three-questionnaire used in the study comprehensively included all issues from general health after cancer surgery to problems faced by the patients specifically after various modalities of rectal surgery. Such studies should be planned routinely to assess comprehensive outcome of oncogenic surgeries.

2012 ◽  
Vol 30 (4) ◽  
pp. 252-257 ◽  
Author(s):  
Eliane Cristina Ferro ◽  
Angelo Piva Biagini ◽  
Ícaro Eduardo Fuchs da Silva ◽  
Marcelo Lourenço Silva ◽  
Josie Resende Torres Silva

Background The aim of the present study was to investigate the efficacy and tolerability of acupuncture (AC), Tanacetum (TAN) or combined treatment on quality of life in women with chronic migraine (CM). Methods A total of 69 women volunteers were randomly divided into 3 groups: AC, acupuncture administered in 20 sessions over 10 weeks (n=22); TAN, at 150 mg/day (n=23); and AC+TAN (n=23). The primary outcome was Short-Form 36 (SF-36) quality of life assessment score. Secondary outcomes included the Migraine Disability Assessment (MIDAS) and visual analogue scale (VAS) score experienced after randomisation. Results AC+TAN was statistically significantly more effective than AC or TAN alone in overall health-related quality of life (SF-36; p<0.05), on MIDAS score (−35.1 (10.6) AC vs −24.8 (11.7) TAN vs −42.5 (9.8) AC+TAN; p<0.05) and in reducing the mean score of pain on VAS (−5.6 (2.4) AC vs −3.7 (2.1) TAN vs −6.4 (3.1) AC+TAN; p<0.05). Conclusions The present work shows an improvement of the quality of life and better analgesic effect of acupuncture combined with TAN treatment on migraine pain in women when compared with acupuncture or TAN alone.


2002 ◽  
Vol 36 (12) ◽  
pp. 1851-1855 ◽  
Author(s):  
Alan F Goodfellow ◽  
Amy O Wai ◽  
Luciana Frighetto ◽  
Carlo A Marra ◽  
Barbara M Ferreira ◽  
...  

OBJECTIVE: To measure changes and to identify predictors of change of health-related quality of life (HRQoL) for enrollees into an outpatient parenteral antibiotic therapy (OPAT) program. METHODS: A multidisciplinary, single-center, prospective investigation was conducted at a 1000-bed Canadian adult tertiary-care teaching hospital. Over a 15-month study period, consenting patients who were enrolled in the OPAT program completed paired Short Form-36 (SF-36) questionnaires within 48 hours prior to discharge from the hospital and again 26–30 days after discharge. Sociodemographic data and clinical variables were also collected for the purpose of determining potential predictors of change in quality of life. RESULTS: During the study period, 134 patients were enrolled in the OPAT program and 82 completed the paired SF-36 questionnaires. Study participants experienced a significant improvement in 3 SF-36 domains (physical functioning, bodily pain, role emotional) and the mental component summary scale (MCS) scores when they were transferred from the hospital to home setting. The SF-36 scores for all domains and summary scales were lower than the Canadian population average (all p < 0.001). Multiple linear-regression analysis revealed that infectious disease diagnosis and baseline physical component summary scale (PCS) scores were predictors of the change in the PCS score when patients transferred from the hospital to the home setting. Length of hospital stay and baseline MCS scores were predictors of the change in MCS scores when patients transferred from the hospital to the home setting. CONCLUSIONS: This study reveals that some domains in HRQoL appear to improve 4 weeks after discharge for adults enrolled in an OPAT program and that there are different predictors for changes in physical and mental health.


Author(s):  
Hariyono Winarto ◽  
William Halim

Abstract Objective: To determine the quality of life in cancer patients who underwent chemotherapy treatment.Methods: A cross-sectional study was conducted from June to August 2019. Patients with cancer, who had undergone chemotherapy and willing to participate were included in this study. The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-30 (EORTC QLQ–30) questionnaire was used as the measurement tool. The patients were grouped into three groups based on the cycles of chemotherapy.Results: Sixty three responders participated in the study. As the treatment progressed, there was a signifi cant decrease in Global Health Status (GHS) and social function. In symptom scales, there was a signifi cant increase in nausea and vomiting, pain, and insomnia.Conclusions: There was a decrease in the quality of life in patients with gynecological cancer who underwent chemotherapy in dr. Cipto Mangunkusumo National General Hospital. This result should be an evaluation for the healthcare provider to implement a holistic approach in managing cancer patients.Keywords: chemotherapy, gynaecological cancer, quality of life.  Abstrak Tujuan: Untuk menilai kualitas hidup pasien kanker yang menjalani kemoterapi.Metode: Penelitian dilakukan dengan metode potong lintang, dilakukan dari Juni hingga Agustus 2019. Semua pasien dengan kanker yang menjalani kemoterapi dan bersedia mengikuti penelitian diikutsertakan dalam penelitian ini. Penilaian dilakukan menggunakan kuisioner dari The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-30 (EORTC QLQ- 30) digunakan. Pasien dikelompokkan menjadi 3 kelompok berdasarkan siklus kemoterapinya.Hasil: Terdapat 63 pasien yang berpartisipasi dalam penelitian ini. Seiring pengobatan, terdapat penurunan signifikan pada global health status (GHS) dan fungsi sosial. Gejala yang meningkat secara signifi kan antara lain mual dan muntah, nyeri, dan insomnia.Kesimpulan: Terdapat penurunan kualitas hidup pada pasien kanker ginekologi yang menjalani kemoterapi di Rumah Sakit Dr. Cipto Mangunkusumo. Hasil penelitian ini menjadi evaluasi untuk penyedia layanan kesehatan agar dapat menangani pasien kanker secara holistik.Kata kunci: kanker ginekologi, kemoterapi, kualitas hidup.


2019 ◽  
Vol 27 (2) ◽  
pp. 147-166
Author(s):  
E.B. Usmanova ◽  
O.Yu. Schyolkova ◽  
G.L. Isurina ◽  
E.A. Sushentsov ◽  
A.K. Valiev ◽  
...  

European Organization of Research and Treatment of Cancer (EORTC) Bone Metastases (BM22), developed by the Quality of Life Assessment Group, is a specialized module of the quality of life questionnaire EORTC QLQ-C30, assessing the quality of life in patients with bone tumors. The aim of the study is to develop its Russian version. The study included a sample of 139 patients with bone tumors — inpatients of N.N. Blokhin Cancer Research Center. The scale has a good convergent validity and internal consistency (0,871), factor analysis confirmed the structure of the scale and its compliance with the original model. The results revealed significant decrease in quality of life due to patients’ focus on pain and its severity. We conclude by drawing out the main directions of psychological aid to patients with bone tumors.


2006 ◽  
Vol 52 (1) ◽  
pp. 33-47
Author(s):  
Carlos Henrique Debenedito Silva ◽  
Sophie Françoise Mauricette Derchain

Objetivo: Verificar quais são os instrumentos utilizados na avaliação da qualidade de vida em mulheres com câncer ginecológico: em protocolos clínicos, durante o tratamento, após o tratamento e aplicado em cuidados paliativos. Método: Foi realizada uma revisão dos trabalhos que empregassem questionário(s) ou entrevista(s) em mulheres com câncer genital, sendo patologia única ou não na casuística, publicados no MEDLINE. Os artigos deveriam contemplar pacientes adultas a partir de 45 anos de idade, publicados nos últimos cinco anos, em língua inglesa. Inicialmente foram identificados 474 artigos, dos quais 30 foram utilizados para o presente trabalho. Resultados: A variedade de instrumentos e de aplicação foi grande. Alguns instrumentos foram de autopreenchimento no hospital, consultório ou por correio e outros eram aplicados por terceiros no hospital ou consultório ou por telefone. Tal variação dependeu da etapa do tratamento, do estágio inicial ou avançado da neoplasia, do tipo de desenho do estudo e do objetivo principal declarado. Os questionários mais utilizados foram o Functional Assessment of Cancer Therapy-General Scale (FACT-G), o European Organization for Research and Treatment of Cancer Quality-of-Life Questionnaire (EORTC QLQ) e o Medical Outcomes Study Short Form-36 (MOS SF-36). Conclusão: Mesmo com restrições apontadas, os autores se mostraram, na maioria, entusiastas com os instrumentos como meio de validar suas propostas terapêuticas.


2015 ◽  
Vol 2 (2) ◽  
pp. 195 ◽  
Author(s):  
Lyda Fabiola Vallejo Castillo ◽  
Pedro Antonio Calero Saa ◽  
Sandro Gustavo Lemus

Introducción: Pese a la existencia de una brecha en la medición de la calidad de vida o el estado de salud individual en función de la percepción del individuo y la percepción de su bienestar, actualmente existen instrumentos en los cuales diferentes ciencias unen esfuerzos para construir herramientas que involucran un abordaje multidimensional para medir el estado funcional en pacientes crónicos. Objetivo: Identificar escalas de valoración de la calidad de vida en el cáncer de mama. Materiales y métodos: Se hizo una búsqueda sistemática de estudios de evaluación de la calidad de vida en cáncer de mama, publicados desde el año 2000. En las bases de datos PubMed, Medline y Cochrane, se identificaron los estudios que cumplían con los siguientes criterios de inclusión: estudios experimentales o cuasiexperimentales que utilizaran diversas escalas para la valoración de la calidad de vida en mujeres con cáncer de mama, que estuvieran en revistas indexadas y que se relacionaran con el tema tratado. Conclusiones. De los diferentes cuestionarios identificados en la revisión, se destacan cuatro que son los más utilizados a nivel internacional y que cuentan con validaciones que les permite aplicarlos en diferentes países: el European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ-C30), el Functional Assesment of Cancer Therapy (FACT-B), el Short Form-36 (SF-36) y el European Organization for Research and Treatment of Cancer BR-23 (EORTC BR-23). Palabras clave: calidad de vida, neoplasias de mama, cuestionarios. 


Author(s):  
Fernando Cancella Da Silva ◽  
Wilel de Almeida Benevides ◽  
Thiago Alexandre Alves da Silva ◽  
Luciana Silveira Monteiro ◽  
Pedro Costa Benevides

Objective: To evaluate the quality of life of patients undergoing ankle arthrodesis through functional scores such as the American Orthopedic Foot & Ankle Society (AOFAS) scale adapted for the Portuguese language and the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36). Methods: A descriptive cross-sectional study was carried out between January 2005 and December 2016, with 26 patients undergoing anklearthrodesis. Two quality of life assessment questionnaires were applied: the AOFAS in the pre- and postoperative period and the SF-36 in the postoperative period. Descriptive and analytical statistical analyses were performed using SPSS, version 23. Results: The main findings are related to the correlations of functional capacity (p=0.002; R²=0.42), limitation due to physical aspects (p=0.05; R²=0.19) and pain (p=0.006; R²=0.35) with age as the predictor and the correlation between preoperative AOFAS scores (p=0.03; R²=0.27) and the aetiology of arthrodesis as the predictor. Conclusion: Ankle arthrodesis is a procedure capable of improving the quality of life of the patient as a whole, including the physical, social, emotional and mental health aspects, rather than pain alone, which has been the main objective of the procedure until the present moment. Level of Evidence II; Prognostic Studies.


2019 ◽  
Vol 13 (2) ◽  
pp. 172-178
Author(s):  
Wrgelles Godinho Bordone Pires ◽  
Philipe Eduardo Carvalho Maia ◽  
Felipe Daniel Vasconcelos de Carvalho ◽  
Rodrigo Simões Castilho ◽  
Fernando Araújo Silva Lopes ◽  
...  

Objective: To assess the quality of life and functional status of patients subjected to debridement of ulcers in the posterior ankle who required complete Achilles tendon resection without any type of reconstruction or tendon transfer. Method: This is a case series of 5 (mostly diabetic) patients who underwent complete Achilles tendon resection due to an ulcer in the posterior ankle region. Preservation of the Achilles tendon was prevented due to tendon exposure, extensive degeneration and the need for infection control. Patients answered the Brazilian Portuguese version of the Achilles Tendon Total Rupture Score (ATRS-BR) questionnaire and the 36-item Short-Form Health Survey (SF-36) during the postoperative period, and follow-up varied between 6 and 24 months. The ATRS-BR ranges from 0 to 100, and higher scores indicate fewer symptoms and limitations. The SF-36 consists of 36 questions comprising 8 domains, which are independently assessed and given a score of up to 100 points, with higher scores indicating better health status. Results: The mean age of patients was 70 years. The mean score on the SF-36 physical functioning domain was 70 (50-95) points. The mean value of the ATRS-BR was 54.6 (31-88) points; however, the patients had few complaints about their functional status. Conclusion: Non-reconstruction of the Achilles tendon in predominantly diabetic elderly patients with posterior ankle ulcers presents encouraging functional outcomes. This study suggests that complete Achilles tendon resection is a viable option for ulcer treatment in this population. Level of Evidence IV; Therapeutic Studies; Cases Series.


2021 ◽  
Vol 24 (4) ◽  
Author(s):  
Jakub Marchewka ◽  
Wojciech Marchewka ◽  
Edward Golec

Introduction: Distal radius fractures (DRFs) are among the most commonly seen types of fractures worldwide. Numerous studies suggested that surgical treatment of DRFs results in better quality of life. Objectives: The aim of this study was to assess long-term quality of life after operative and nonoperative treatment of distal radius fractures among adults. Material and methods: We retrospectively studied 207 patients with isolated DRF (mean age 64 ±17.9 years, women comprised 150 (72.5%), men 57 (27.5%). There were no significant differences in sex, age, hand dominancy, energy of trauma, AO type fracture and comorbidities between patients treated operatively (n=101) and nonoperatively (n=106). After 3.9 ±1.6 years (mean ±SD) quality of life assessment was conducted using Short Form Health Survey (SF-36) and International Osteoporosis Foundation Quality of Life Questionnaire (IOF QLQ). Functional outcomes were evaluated using Disabilities of the Arm, Shoulder and Hand (DASH) and Patient Rated Wrist Evaluation (PRWE) questionnaires. Results: Quality of life in operatively treated distal radius fracture patients was better than amongst those treated nonsurgically. However, after subdivision of cohorts we observed no such differences regardless of treatment method in patients aged ≥ 50 years. SF-36 and IOF QLQ scores were correlated with DASH and PRWE results. Conclusions: Quality of life questionnaires are useful tools for determining outcomes after distal radius fractures. Operative treatment may not always be superior to nonoperative management especially in patients aged 50 years or above with distal radius fractures.


Cancers ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 219
Author(s):  
Hiromitsu Iwata ◽  
Hiroyuki Ogino ◽  
Yukiko Hattori ◽  
Koichiro Nakajima ◽  
Kento Nomura ◽  
...  

This study retrospectively investigated the efficacy and safety of image-guided proton therapy (IGPT) for elderly (≥80 years old) hepatocellular carcinoma (HCC) patients. Proton therapy was performed using respiratory-gated and image-guided techniques. Seventy-one elderly HCC patients were treated using IGPT. The Child–Pugh score was A5 in 49 patients, A6 in 15, and B7-9 in 7. Forty-seven patients with a peripherally located tumor were administered 66 gray relative biological effectiveness (GyRBE) in 10 fractions, whereas 24 with a centrally located tumor received 72.6 GyRBE in 22 fractions. The median follow-up period of surviving patients was 33 months (range: 9–68). Two-year overall survival (OS) and local control (LC) rates estimated by the Kaplan–Meier method were 76% (95% confidence interval: 66–87%) and 88% (80–97%), respectively. According to the Common Terminology Criteria for Adverse Events version 4.0, no grade 2 or higher radiation-induced liver disease was observed, and only 1 patient developed grade 3 dermatitis. The quality of life score (European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30 version 3.0, QLQ-HCC18, and SF-36) did not change after 1 year, except for the three-mental component summary (SF-36, improvement). IGPT is a safe and effective treatment for HCC in elderly patients.


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