scholarly journals A study on diagnostic accuracy of modified triple assessment in palpable breast lumps

2021 ◽  
Vol 8 (8) ◽  
pp. 2350
Author(s):  
Radha K. ◽  
Uma M.
Keyword(s):  
Diagnostic Accuracy ◽  
Benign Tumor ◽  
Nipple Discharge ◽  
Breast Diseases ◽  
Histopathological Diagnosis ◽  
Common Benign Tumor ◽  
Triple Test ◽  
Triple Assessment ◽  
Palpable Breast ◽  
Breast Lumps

Background: Breast (mammary gland) is a distinguishing feature of class Mammalia. Patients commonly present, complaining of a lump in the breast, pain, and nipple discharge. Although the most common cause of symptoms is benign breast diseases. But as the life expectancy is increasing incidence of carcinoma breast is also increasing. 1.To assess the individual component diagnostic accuracy of MTT.Methods: This was a cross-sectional study involving 50 female patients with palpable breast lumps attending the Surgical Out-Patient of the Department of General Surgery, Government Royapettah Hospital, Kilpauk medical college, Chennai between June 2020 and May 2021 over 12 months, who underwent clinical breast examination (CBE), ultrasonography (USG), and fine-needle aspiration cytology (FNAC). Results: In the study population, the breast tumor is common on the left side account for about overall 53%age of patients. The bilateral tumors are the least common. Fibroadenoma is the most common benign tumor. In our study also similar results were obtained. The next common benign tumor among the study group is a fibrocystic disease of the breast. Analysis of the above results shows that though FNAC has a sensitivity of 90%, it has a positive predictive value of 100%. The study shows that the combined results of the Modified Triple Test are comparable to the histopathological diagnosis of the biopsy specimen. Conclusions: Our study includes assessment of combined diagnostic accuracy of Modified Triple Test in women of more than 30 years of age with a palpable breast lump.

Benign breast diseases

2018 ◽  
pp. 499-504
Author(s):  
Abdullah Jibawi ◽  
Mohamed Baguneid ◽  
Arnab Bhowmick
Keyword(s):  
Breast Imaging ◽  
Age Groups ◽  
Nipple Discharge ◽  
Surgical Excision ◽  
Clinical History ◽  
Breast Diseases ◽  
Management Options ◽  
Breast Infection ◽  
Triple Assessment ◽  
Breast Lumps

Benign breast lesions (fibroadenoma, breast cysts, breast pain, gyanecomastia, and breast infection) are common, and affect different age groups. Presentation ranges from well-defined breast lumps into spreading infection and nipple discharge. Triple assessment is the mainstay of diagnosis (clinical history and examination, breast imaging, and pathological assessment of biopsy). Management options include conservative wait and watch policy, into surgical excision and ultrasound-guided aspiration.

scholarly journals A PROSPECTIVE STUDY OF TRIPLE ASSESSMENT IN EVALUATION OF BREAST LUMP

2021 ◽  
Vol 9 (03) ◽  
pp. 65-71
Author(s):  
M. Vishnuteja ◽  
◽  
Suman Saurav Rout ◽  
Prakash Kumar Sahoo ◽  
◽  
...  
Keyword(s):  
Imaging Modality ◽  
Nipple Discharge ◽  
Breast Lump ◽  
Suitable Alternative ◽  
Additional Information ◽  
Triple Assessment ◽  
Palpable Breast ◽  
Breast Lumps ◽  
Representative Area ◽  
A Prospective Study

Breast masses have a variety of etiologies, benign and malignant. Most masses are benign, but breast cancer is the most common cancer and the second leading cause of cancer deaths in women. The Study is done with an aim of assessing the added and singular dependability of modified triple testing in making a pre-procedural diagnosis of a breast lump. A random sample of 150 patients attending the surgery outpatient department was taken. Of the 150 patients presenting with breast lumps most of the lumps were painless 81.3%(n=122),10% (n=16)of the lumps were associated with pain and 8%(n=12) were associated with nipple discharge. A fine collaboration between experienced radiologists, cytologist and the Clinician is required.Ultrasound when replacing mammography serves as effective an imaging modality in palpable breast lumps and is more comprehensive.Ultrasound breast aids biopsy techniques by guidance to the representative area than increasing yield. CNB is a suitable alternative when FNA is inconclusive and may offer additional information. Thus the use of Modified Triple Test( MTT) to complement findings in differential diagnosis of a lesion in a symptomatic women seeking medical care deserves acceptance and further evolution. This may lead to less delay in treatment when malignancy is suspected and to avoidance of surgical exploration when a benign nature of lesion is suspected.

scholarly journals DIAGNOSTIC ACCURACY OF TRIPLE ASSESSMENT IN PALPABLE BREAST LUMP

2020 ◽  
pp. 1-3
Author(s):  
Sitesh Kumar Karn ◽  
Ramesh Kumar Ajai ◽  
Debarshi Jana
Keyword(s):  
Diagnostic Accuracy ◽  
Clinical Examination ◽  
Histopathological Examination ◽  
False Negative ◽  
Excisional Biopsy ◽  
Needle Aspiration ◽  
Triple Test ◽  
Triple Assessment ◽  
Palpable Breast ◽  
Needle Aspiration Cytology

Background:Breast diseases constitute a heterogeneous group of lesions including developmental abnormalities,inflammatory lesions, epithelial and stromal proliferations, and neoplasms. With the use of clinical examination, mammography and fine needle aspiration cytology (FNAC), the diagnosis of a benign breast disease can be accomplished without surgery in the majority of patients. Combined use of these diagnostic procedures (Triple assessment) gives nearly the same degree of accuracy as excisional biopsy in patients with palpable breast diseases. Currently a combination of three tests, i.e. clinical examination, radiological imaging (mammography, ultrasonography) and pathology called as triple assessment test is used to accurately diagnose all palpable breast lumps. The Triple Test Score (TTS) was developed to help physicians interpret discordant triple test results. A three-point scale is used to score each component of the triple test (1 = benign, 2 = suspicious, 3 = malignant). A TTS of 3 or 4 is consistent with a benign lesion; a TTS of 6 or more indicates possible malignancy that may require surgical intervention. Excisional biopsy is recommended in patients with a TTS of 5 to obtain a definitive diagnosis. Materials and methods: The study was conducted for diagnostic accuracy of triple assessment in palpable breastlump in 50 patients. The components of the Triple Assessment are: Clinical examination (C/E), Mammography/ ultrasonograph and Fine Needle Aspiration Cytology (FNAC). The diagnostic accuracy of triple asseserment was reached by comparing the results of this test with gold standard i.e. histopathological findings. Results :The TT was concordant in 46 cases (92%). In 17 of these lesions (34%), the results of TT were interpretedas benign and subsequently were proved to be benign pathologies histologically with NPV and Specificity of 100٪.Similarly, in 29 cases (58٪) the results of all elements of TT were interpreted as malignant, which proved to be malignant lesions on histopathological examination and the sensitivity and PPV were 100 ٪ .TT elements were non concordant in 4 cases (8٪), 3 of these cases were proved to have malignant masses and the remaining 1 case was proved to be benign on subsequent histopathological examination. In all the non concordant cases, where at least one of the elements was considered benign, FNAC was the most accurate with 0 false negative and 0 false positive results. Conclusion: The TT has proved to be accurate, reliable diagnostic approach for evaluation of breast masses, achieved(100%) accuracy rate when all elements were concordant or when all elements were either suspicious or malignant. The study shows that when TT is concordant, final treatment may be ensued without open biopsy. In non-concordantcases, FNAC stands as single most important investigation. However due to its false negative results, other components of triple test need to be employed to enhance its efficacy and diagnostic yield.

Benign Breast Disease

2017 ◽  
Author(s):  
Stephanie A Valente ◽  
Stephen R Grobmyer
Keyword(s):  
Benign Breast Disease ◽  
Nipple Discharge ◽  
Breast Disease ◽  
Breast Diseases ◽  
Breast Pain ◽  
Idiopathic Granulomatous Mastitis ◽  
Breast Cyst ◽  
Benign Breast Diseases ◽  
Palpable Breast ◽  
Management Recommendations

Benign breast disease constitutes any abnormality that upon further workup is found to be noncancerous and does not establish premalignant potential. Benign breast diseases can present in various ways, such as breast pain, a palpable breast lump, nipple discharge, or an imaging abnormality. Appropriate workup is essential to ensure that the new change is benign. This may entail additional imaging, biopsy, or surgery if necessary. Surgeons need to be able to recognize the presentation, appropriate workup, and treatment recommendations for the various benign breast diseases. This review addresses the broad range of benign breast lesions and their management recommendations.  This review contains 7 figures, 5 tables and 54 references Key words: benign breast disease, breast cyst, breast mass, breast pain, idiopathic granulomatous mastitis, nipple discharge, papilloma, periductal mastitis, sclerosing adenosis

scholarly journals Cytopathological Patterns of Palpable Breast Lumps on Fine Needle Aspiration - A Hospital Based Study

2021 ◽  
Vol 8 (06) ◽  
pp. 319-326
Author(s):  
Dharmakanta Kumbhakar ◽  
Partha Pratim Talukdar
Keyword(s):  
Diagnostic Accuracy ◽  
Fine Needle Aspiration ◽  
Predictive Value ◽  
Needle Aspiration ◽  
Malignant Neoplasms ◽  
Duct Carcinoma ◽  
Female Ratio ◽  
Fine Needle ◽  
Palpable Breast ◽  
Breast Lumps

BACKGROUND The breast is composed of both specialised epithelial cells and stroma. Both benign and malignant lesions can occur in the breast as a palpable lump. Fine needle aspiration cytology (FNAC) is a rapid, easy to perform, minimally invasive and low cost first line high-diagnostic accuracy test for cytopathological evaluation of palpable breast lump with minimum complications. METHODS The study was carried out to evaluate the cytopathological patterns of 2706 palpable breast lumps by fine needle aspiration (FNA) procedure and cytohistopathological correlation of the available biopsied palpable breast lumps of the study in the Pathology department of Tezpur Medical College and Hospital, Assam, for a period of three years from July 01, 2016 to June 30, 2019. RESULTS Out of 2706 palpable breast lumps in the study, FNA smears of 19 (0.70 %) were inadequate for cytopathological reporting. Out of the remaining 2687 palpable breast lumps where FNA was adequate for cytopathological reporting, female patients (n = 2594) comprised 96.54 % and male patients (n = 93) comprised 3.46 % with a male and female ratio of 1:27.9. Out of the 2687 palpable breast lumps, 2318 were benign breast diseases (86.27 %) and 369 were malignant neoplasms (13.73 %), with a benign and malignant ratio of 6.28:1. Out of the benign breast lumps, fibroadenoma breast was seen in 1228 (52.98 %) and of the malignant neoplasms, infiltrating duct carcinoma was seen in 341 (92.41 %). Cytohistopathological correlation showed 98.70 % sensitivity, 99.38 % specificity, 99.35 % positive predictive value, 98.76 % negative predictive value, and 99.04 % diagnostic accuracy. CONCLUSIONS FNAC has high sensitivity and specificity in cytopathological diagnosis of palpable breast lumps. Based on the accurate cytopathological diagnosis of the palpable breast lumps, patients with palpable breast lumps can be given adequate treatment. KEYWORDS Fibroadenoma, Gynaecomastia, Duct Papilloma, Infiltrative Duct Carcinoma, Medullary Carcinoma, Mucinous Carcinoma, Malignant Phyllodes

scholarly journals Histopathological study of benign breast lesions

2021 ◽  
Vol 6 (4) ◽  
pp. 295-300
Author(s):  
M Janaki ◽  
R Poojasree ◽  
M Anil Kumar ◽  
A Hareesh Kumar ◽  
T Nagachandana
Keyword(s):  
Histopathological Examination ◽  
Nipple Discharge ◽  
Breast Diseases ◽  
Histopathological Study ◽  
Breast Lesions ◽  
Young Females ◽  
Benign Breast Diseases ◽  
Different Types ◽  
Benign Breast Lesions ◽  
Breast Lumps

Benign breast lesions are common in young females and are painless. Fibroadenoma is the commonest lesion among all the breast lesions and occurs in any age.1:To study the age and sex wise distribution of benign breast lesions; 2: To study the clinicopathological changes of benign breast diseases; 3: To study different types of benign breast lesions; 4. To study the histomorphological changes of benign breast lesions with clinical correlation.A prospective study of two years was done to evaluate the different types, patterns of benign breast lesions in females in relation to age, clinical and radiological features.A total of 140 benign breast diseases were studied. Fibroadenoma (76; 54.2%) was the most common lesion noted in younger females (18-24yrs) followed by fibrocystic disease (25; 17.8%) & benign phyllodes (14; 10%).FNAC followed by histopathological examination were the diagnostic criteria used for confirmation of the lesions.Benign breast lesions were common in young females, presented with painless, mobile breast lumps. Mastalgia and nipple discharge were other symptoms.

scholarly journals Age and Gender Distribution of Benign Breast Lesions of Women at Port City of Bangladesh

2018 ◽  
Vol 16 (1) ◽  
pp. 27-31
Author(s):  
Nazmun Nahar ◽  
Mohammed Iqbal ◽  
Kazi Md Shahidur Rahman ◽  
Sabrina Razzaque ◽  
Farida Yeasmin ◽  
...  
Keyword(s):  
Histopathological Examination ◽  
Nipple Discharge ◽  
Benign Neoplasm ◽  
Breast Disease ◽  
Pathological Examination ◽  
Breast Diseases ◽  
Cross Sectional ◽  
Medical College ◽  
Benign Breast Diseases ◽  
Triple Assessment

Background: Benign breast diseases are the most common cause of breast problems. The most common symptoms are breast pain, lumpiness or a lump and nipple discharge. Triple assessment that includes clinical examination, imaging like ultrasonography (USG) or mammography and a pathological examination – FNAC or core needle biopsy has a very high accuracy rate in diagnosing, discrete benign breast diseases and this can be used for reassurance.Objective: The purpose of the present study was to determine the frequency of different types of benign neoplasm of breast lump in different age and sex.Methodology: The present study was carried out at the Department of Pathology, Chittagong Medical College, Bangladesh one year period from May 2005 to June 2006. This study was cross sectional which included 48 cases of breast neoplasm. The specimens were received from indoor patient Department of Surgery, Chittagong Medical College, Bangladesh. Histopathological examination was done.Results: This study shows the mean age of the patients was 32.91 years with age range 11 to 70 years. Most of the patients were in 31 to 50 years (45.8%) age group and female predominance than male. Fibroadenoma accounted for 76.2%. Sclerosing adenosine the second most common benign breast disease in this study accounted for 9.5% of cases.Conclusion: This study showed that among the benign breast diseases in females there were preponderance of fibroadenoma followed by sclerosing adenosineJournal of Science Foundation 2018;16(1):27-31

scholarly journals Ultrasonographic Elasticity Contrast Index of Palpable Breast Lumps

2018 ◽  
Vol 56 (212) ◽  
pp. 787-790
Author(s):  
Anamika Jha
Keyword(s):  
Cross Sectional Study ◽  
Receiver Operating Curve ◽  
Histopathological Diagnosis ◽  
Health Care Centre ◽  
Cross Sectional ◽  
Breast Sonography ◽  
Malignant Lesions ◽  
Palpable Breast ◽  
Breast Lumps ◽  
Evaluation Of Data

Introduction: Elastrography used in addition to grey scale sonography increases its specificity. Elasticity contrast index (ECI) is based on strain elastrography and being a quantitative parameter, maybe more easy to obtain and reproducible while researches has been done in ECI in thyroid lesions, this is the first study, to the best of our knowledge to evaluate in breast lesions. This study was done to evaluate the diagnostic accuracy of Elasticity Contrast Index (ECI) in differentiating benign from malignant lesions of breast and to determine its cutoff value. Methods: This is a descriptive cross-sectional study done at tertiary health care centre, which involved retrospective evaluation of data collected from September 2016 to March 2017. Conventional sonography was done followed by elastography on commercially available ultrasound machine. ECI was calculated in thyroid protocol available in the unit. Histopathological diagnosis was obtained for all the lesions and taken as gold standard. Results: A total of 89 breast lumps were evaluated, of which was 61 (69.3%) were benign and 27 (30.7%) malignant on histopathology. Independent t test revealed the average ECI value of benign lesions was 2.48 and malignant 5.1. Receiver operating curve showed ECI value of 3.25 as the cutoff, above which the lesions were malignant. Conclusions: ECI is a quantitative elastography technique which can be easily used as an adjunct during breast sonography and can increase its specificity for diagnosing a lesion as malignant. This could reduce the number of false positive biopsies.

scholarly journals Accuracy of Triple Test Score in The Diagnosis of Palpable Breast Lump

2008 ◽  
Vol 47 (172) ◽  
Author(s):  
Bikal Ghimire ◽  
MI Khan ◽  
T Bibhusal ◽  
Y Singh ◽  
P Sayami
Keyword(s):  
Diagnostic Test ◽  
Test Score ◽  
Needle Aspiration ◽  
Definitive Treatment ◽  
Breast Diseases ◽  
Clinical Tool ◽  
Breast Lump ◽  
Triple Test ◽  
Test Study ◽  
Breast Lumps

Breast lump is a very sensitive issue for the patient so a reliable, non invasive and prompt diagnosishelps to lessen the associated anxiety and leads to early definitive treatment. The aim of this studywas to evaluate the acuracy of Triple Test Score (TTS) as a clinical tool for the diagnosis of a palpablebreast lump. This diagnostic test study was carried out in the Department of Surgery of TribhuvanUniversity Teaching Hospital. Of the 117 patients admitted with breast diseases from the breastclinic over thirteen months, 87 had breast lump. Fifty patients underwent Triple Test Score ( physicalexamination, mammography and fine needle aspiration cytology) and were categorized into benign,suspicious and malignant. This was later correlated with the histopathological findings. Nineteenpatients with breast lumps interpreted by TTS as benign correlated with the histopathologicalfindings whereas of 31 malignant lumps, 30 turned out to be malignant and one benign. This givesTTS an over all accuracy of 98% with 100% sensitivity, 95.2% specificity and positive predictive valueof 96.7%. Carcinoma was seen in 29 (58%) cases in the age group of 35 to 70 years. The mean age atdiagnosis of benign and malignant disease was 41.8 and 45.1 years respectively. In conclusion, TTS isan accurate and least invasive diagnostic test based on which definitive treatment can be initiated.Key words : breast lump, carcinoma breast, triple test score

scholarly journals Epidemiology of benign breast lumps, is it changing: a prospective study

2019 ◽  
Vol 6 (2) ◽  
pp. 465
Author(s):  
Navin Kumar ◽  
Janardan Prasad
Keyword(s):  
Needle Aspiration ◽  
Screening Mammography ◽  
Breast Diseases ◽  
Oral Contraceptive Pills ◽  
Benign Breast Diseases ◽  
Contraceptive Pills ◽  
Triple Assessment ◽  
Wide Range ◽  
Breast Lumps ◽  
A Prospective Study

Background: There are wide range of benign breast diseases reported from India. Breast lumps are one of the commonest presentations. Although most of the breast lumps are benign but patient become anxious due to fear of malignancy. Due to this, there is an increase in the use of screening mammography and the fine needle aspiration cytology (FNAC) or core needle biopsy (CNB), most of which yield benign findings. This study is aimed to evaluate the incidence of different types of benign breast lumps in respect to age, size, side and site, relation with parity and use of oral contraceptive pills and analyses of this result in relation with the past and recent study on benign breast diseases.Methods: This study was conducted at Rajendra Institute of Medical Sciences, Ranchi (India) over a period of one and half years. Inclusion criteria was the cases with palpable breast lumps which were reported benign on either FNAC or CNB and exclusion criteria was the cases with breast malignancy and inflammatory breast lumps.Results: Most common benign breast lump (BBL) was fibroadenoma followed by fibrocystic disease of breast. Fibroadenoma was mainly presented with lump only whereas fibrocystic diseases of breast presented with lump and pain. Most of the BBL was found in nullipara and OCP non-users.Conclusions: Epidemiology of BBL is still the same when analyzed with past and recent study on the benign breast diseases. Triple assessment remains the key in the evaluation of breast lumps.

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