Patients with benign breast disease and breast cancer need more COVID-19 vaccines

Albeit the efficacy of COVID-19 vaccines in immunocompromised patients is undermined, it is still found beneficial. Patients with cancer have a much lower COVID- 19 vaccination rate globally, and the vaccination coverage in breast cancer patients in China remains elusive. A total of 23029 patients with benign breast diseases and breast cancers were included in the study, and the vaccination rates of patients with benign breast tumors and other benign breast diseases, nonmetastatic and metastatic breast cancer were 44.0%, 54.7%, 19.2% and 9.6%, respectively. Breast cancer in situ patients had a similar vaccination rate with patients with benign breast tumors (45.9% vs 44.0%) while those with invasive breast cancer had much lower vaccination rates. The overall vaccination rate remains meager in breast cancer patients, and gap was found in patients with lower clinical stage. Hence vaccination should be further promoted among patients with benign breast diseases and breast cancer.

Histopathological study of benign breast lesions

Benign breast lesions are common in young females and are painless. Fibroadenoma is the commonest lesion among all the breast lesions and occurs in any age.1:To study the age and sex wise distribution of benign breast lesions; 2: To study the clinicopathological changes of benign breast diseases; 3: To study different types of benign breast lesions; 4. To study the histomorphological changes of benign breast lesions with clinical correlation.A prospective study of two years was done to evaluate the different types, patterns of benign breast lesions in females in relation to age, clinical and radiological features.A total of 140 benign breast diseases were studied. Fibroadenoma (76; 54.2%) was the most common lesion noted in younger females (18-24yrs) followed by fibrocystic disease (25; 17.8%) & benign phyllodes (14; 10%).FNAC followed by histopathological examination were the diagnostic criteria used for confirmation of the lesions.Benign breast lesions were common in young females, presented with painless, mobile breast lumps. Mastalgia and nipple discharge were other symptoms.

PROPORTIONS OF VARIOUS BENIGN BREAST LESIONS AMONG WOMEN PRESENTING AT TERTIARY CARE INSTITUTE OF INDIA: A CROSS-SECTIONAL STUDY

Background and Aim: Benign Breast Diseases (BBDs) is a group of non-cancerous breast diseases. A triple assessment which is done by a clinical examination, imaging like ultrasonography (USG) or mammography and a pathological examination – FNAC or core needle biopsy, during the initial consultation, allows clinicians to give immediate reassurance to most of the patients. The aim of the study was to find out the proportions of various benign breast lesions among women aged 18 years and above. Material and Methods: A prospective study was conducted in the Department of Surgery, Tertiary care institute of India for a period of 20 Months. Based on the pilot study sample size derived was found to be 102. A performa was filled with patient particulars, history and clinical findings in female patient attending department of surgery OPD with breast related symptoms. Patients will be followed up with histopathological, cytological and radiological studies in indicated cases. The patients will be followed up for 1 year. Most common benign breast related symptoms and condition among the study group and probable risk factors for the same will be analyzed. Results:The commonest case among the study population was fibroadenoma 37 (36.27%). The next common was acute breast abscess, followed by fibrocystic disease (9). Lump alone detected either by patient herself or by the clinician was the most common presenting complaint in around 40 patients, followed by lump with pain in around 37, followed by either pain, nipple discharge. Fibroadenoma could be diagnosed clinically with an accuracy of about 89%. Abscess breast, phyllodes tumor and galactocele and few cases of granulomatous mastitis was also able to be diagnosed clinically. Conclusion: Fibrocystic disease is commonest amongst proliferative breast lesions followed by Sclerosing adenosis. Breast abscess is the commonest lesion amongst inflammatory breast lesions. Breast self-examination and health education to females is very important in cases of benign proliferative lesions. Key Words: Benign Breast Diseases, Fibroadenoma, Phyllodes tumor, Ultrasonography

Xiaojin Pill with natural musk in the treatment of plasma cell mastitis

Introduction: Plasma cell mastitis is a rare benign suppurative disease of the breast based on the dilatation of mammary ducts and infiltration of plasma cells. Modern medicine focuses on surgical treatment. It is easy to recur after operation. Xiaojin Pill with natural musk is a oral traditional Chinese medicine and plays a role in benign breast diseases. There are very few reports on the use of Xiaojin Pill with natural musk in treating plasma cell mastitis yet. Cases: This paper reports 3 cases of plasma cell mastitis who received Xiaojin Pill with natural musk treatment. Patients were successfully treated after accepting Xiaojin Pill with natural musk for several weeks.

Cytomorphological study of Benign breast lesions in a Tertiary Care Hospital

Background: Benign breast disease is one of the most common breast lesions in the reproductiveage group. Fine needle aspiration cytology (FNAC) is one of the preliminary tests done to detectbreast lesions which help in early detection and management. Studying the cytology features ofvarious benign breast diseases was the aim of this study. Methods: This study is a cross-sectionalretrospective study conducted in the Department of Pathology from 2015 to 2020. Clinical detailsand cytology features were collected from the Department records. Results: A total of 430 caseswere collected during the study period. Age groups ranged from 16-40 years. All the cases werefemales. The spectrum of lesions was composed of fibroadenoma, fibrocystic change, breastabscess, fibroadenosis, granulomatous mastitis, etc. Conclusions: Breast lumps are a commoncause of anxiety and apprehension among patients. FNAC helps in rapid diagnosis and earlymanagement of lesions. It also helps in preventing unnecessary invasive surgeries in non-neoplasticand benign breast diseases.

Clinicopathological study of benign breast diseases a study of 50 cases

Background: Benign breast diseases are a neglected entity in developing countries despite the fact that they involved in the majority of breast complaints. Benign breast disorders can be defined as any non-malignant breast condition and involved wide range of clinical and pathological disorders. Breast diseases present as swellings. It is a symptom/sign for a different lesion varying from developmental abnormality, inflammatory lesions, epithelial and stromal proliferation to malignancy. Patients were studied on the basis of i.e., clinically, and histopathological ultrasound has done. Our purpose of study is to document various benign Brest diseases to study different mode of presentations of diseases and correlation of clinical and pathological diagnosisMethods: The given study was a prospective and observational study, undertaken in the department of general surgery, govt. medical college Surat, during the study period of March 2018 to September 2019.All the female and male patients with breast related disease were included in this study. Female patients with biopsy proven malignancy were excluded from the study.Results: The study comprised of 50 patients with benign breast diseases; the most common is Fibro adenoma which formed 68% then fibrocystic diseases 20%. With most common age group involved in our study is 21-30 years.Conclusions: Benign breast diseases are more common but ignored entity though it carries majority of complaints and occur mainly in young women less than 30 years of age and were mostly fibro adenoma and fibrocystic change.

Mimickers of breast malignancy: imaging findings, pathologic concordance and clinical management

Many benign breast entities have a clinical and imaging presentation that can mimic breast cancer. The purpose of this review is to illustrate the wide spectrum of imaging features that can be associated with benign breast diseases with an emphasis on the suspicious imaging findings associated with these benign conditions that can mimic cancer. As radiologic-pathologic correlation can be particularly challenging in these cases, the radiologist’s familiarity with these benign entities and their imaging features is essential to ensure that a benign pathology result is accepted as concordant when appropriate and that a suitable management plan is formulated.