scholarly journals Association between serum concentration of vitamin D and development of pneumonia

2019 ◽  
Vol 6 (5) ◽  
pp. 2003
Author(s):  
Abrar Ahmed Siddique ◽  
Mohammed Abdul Saleem
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Case Control Study ◽  
Serum Levels ◽  
Case Control ◽  
Control Group ◽  
Common Disease ◽  
Healthy Children ◽  
The Impact ◽  
Control Study

Background: Pneumonia is a common disease with significant morbidity and mortality. There is evidence that vitamin D deficiency can be associated with an increased incidence of lower respiratory illness requiring hospitalization. The objective of this study investigated the impact of vitamin D status on the susceptibility of pneumonia in children the design is Case - Control study, Duration of this study is One year (October 2016 -November 2017) and Setting is Niloufer Hospital, Hyderabad, India. In this study participants are 50 children aged 5 months to 5 years with pneumonia and 50 healthy children of the same age were studied.Methods: In this case-control study, children aged 5 months to 5 years with pneumonia were compared with healthy children of the same age as the control group. Serum levels of vitamin D in both groups were measured by chemiluminescence method. Mean serum levels of vitamin D in patients with pneumonia and control groups were compared using t test.Results: The mean serum levels of vitamin D in the group with pneumonia and the control group were 25.98±14.8 ng/mL and 31.18±15.81 ng/mL, respectively. The difference between the two groups was significant. However, this difference was more significant in the age group of 24 to 60 months.Conclusions: According to findings, a low level of Vitamin D is associated with a higher incidence of pneumonia and more severe disease. It is recommended to pay more attention to vitamin D deficiency in infectious diseases, particularly in pneumonia patients.

scholarly journals Vitamin D Deficiency in Non-Autoimmune Hypothyroidism: A case-control study

2020 ◽  
Author(s):  
Salma Ahi ◽  
Mohammad Reza Dehdar ◽  
Naser Hatami
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Case Control Study ◽  
Inverse Correlation ◽  
Case Control ◽  
Control Group ◽  
Retrospective Case ◽  
Autoimmune Hypothyroidism ◽  
Control Study

Abstract Objectives: Although in many studies, the relationship between autoimmune hypothyroidism (Hashimoto) and Vitamin D deficiency was shown, no research has been performed on the role of vitamin D in non-autoimmune hypothyroidism. Design: This was a Retrospective case–control study in Endocrinology clinic of Jahrom (south of Iran). The patients with Hashimoto (n=633) and non-Hashimoto hypothyroidism (n=305), along with a control group (n=200) were evaluated. 25(OH)D level, T3 and T4 levels were studied and Anti TPO and Anti TG tests were performed. The results of vitamin D level were analyzed and interpreted using SPSS in terms of the cause of hypothyroidism (immune and non-immune). Results: The results of the study showed a significantly lower level of vitamin D in both immune and non-immune Hashimoto’s thyroiditis (HT) in comparison to healthy controls (P<0.05). We observed a significant inverse correlation between the vitamin D and TGAb level (p=0.001, r=-0.261) and a direct correlation of vitamin D with TSH level (p=0.008, r=0.108) in HT patients. Conclusion: Finally, the results indicated that non-autoimmune hypothyroidism, as well as HT, is associated with vitamin D deficiency. The role of vitamin D deficiency in HT was thought to be in the association of higher autoantibody (TGAb) level; while, there should be further studies determining vitamin D deficiency's role in non-immune hypothyroidism.

scholarly journals The impact of vitamin D deficiency on immune T cells in asthmatic children: a case-control study

2012 ◽  
pp. 11 ◽  
Author(s):  
Agnes Hamzaoui ◽  
Haifa Maalmi ◽  
Anissa Berraïes ◽  
Eya Tanguouru ◽  
Jamel Ammar ◽  
...  
Keyword(s):  
Vitamin D ◽  
T Cells ◽  
Vitamin D Deficiency ◽  
Case Control Study ◽  
Case Control ◽  
Asthmatic Children ◽  
The Impact ◽  
Control Study

scholarly journals THE POSSIBLE LINK BETWEEN VITAMIN D LEVELS AND RESTLESS LEG SYNDROME: A HOSPITAL-BASED CASE-CONTROL STUDY FROM KASHMIR, INDIA

2021 ◽  
Vol 9 (5) ◽  
pp. 1362-1367
Author(s):  
Rehana Amin ◽  
◽  
Seema Batool ◽  
Yuman Kawoos ◽  
Masood Maqbool ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Case Control Study ◽  
Case Control ◽  
Nervous System Development ◽  
Control Group ◽  
P Value ◽  
Restless Leg Syndrome ◽  
Vitamin D Levels ◽  
Control Study

Background & Objectives: Various pathophysiological mechanisms and risk factors have been identified in patients with restless leg syndrome and there exist other factors also that are yet to be identified and are under-researched. Evidence suggests a possible link between Vitamin D deficiency and Restless leg syndrome.The aim was to study the Vitamin D levels in patients diagnosed with RLS and to find a correlation between Vitamin D and RLS. Methods: This was a case-control study carried out in the outpatient department of the Institute of Mental Health and Neurosciences Kashmir.A total of 144 subjects were enrolled in the study. Fifty-one were diagnosed cases of RLS and 93 were healthy controls.The Vitamin D levels were analysed by the chemiluminescent immunoassay method in both cases as well as controls.The descriptive statistics were used for various socio-demographic and clinical variables.The data were analysed by chi-square test, t-test and multivariate logistic regression analysis. Results: The vitamin D levels were significantly low in the RLS group in comparison to the control group. There was a significant correlation between vitamin D levels, vitamin D deficiency and restless leg syndrome (OR= 1.01, p-value 0.005 and OR= 5.40, p-value <0.0001 respectively). Interpretation &conclusions: Vitamin D levels were low in patients with RLS. This signifies vitamin D may have some role in the pathophysiology of RLS.Vitamin D regulates the nervous system development and function therefore, its use can be considered in the management of RLS when other modalities cannot prove as a promising agent.

scholarly journals Vitamin D Deficiency in Non-Autoimmune Hypothyroidism: A case-control study

2019 ◽  
Author(s):  
Salma Ahi ◽  
Mohammad Reza Dehdar ◽  
Naser Hatami
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Case Control Study ◽  
Inverse Correlation ◽  
Case Control ◽  
Control Group ◽  
Retrospective Case ◽  
Autoimmune Hypothyroidism ◽  
Control Study

Abstract Objectives: Although in many studies, the relationship between autoimmune hypothyroidism (Hashimoto) and Vitamin D deficiency was shown, no research has been performed on the role of vitamin D in non-autoimmune hypothyroidism. Design: This was a Retrospective case–control study in Endocrinology clinic of Jahrom (south of Iran). The patients with Hashimoto (n=633) and non-Hashimoto hypothyroidism (n=305), along with a control group (n=200) were evaluated. 25(OH)D level, T3 and T4 levels were studied and Anti TPO and Anti TG tests were performed. The results of vitamin D level were analyzed and interpreted using SPSS in terms of the cause of hypothyroidism (immune and non-immune). Results: The results of the study showed a significantly lower level of vitamin D in both immune and non-immune Hashimoto’s thyroiditis (HT) in comparison to healthy controls (P<0.05). We observed a significant inverse correlation between the vitamin D and TGAb level (p=0.001, r=-0.261) and a direct correlation of vitamin D with TSH level (p=0.008, r=0.108) in HT patients. Conclusion: Finally, the results indicated that non-autoimmune hypothyroidism, as well as HT, is associated with vitamin D deficiency. The role of vitamin D deficiency in HT was thought to be in the association of higher autoantibody (TGAb) level; while, there should be further studies determining vitamin D deficiency's role in non-immune hypothyroidism.

scholarly journals Vitamin D Deficiency in Non-Autoimmune Hypothyroidism: A case-control study

2020 ◽  
Author(s):  
Salma Ahi ◽  
Mohammad Reza Dehdar ◽  
Naser Hatami
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Case Control Study ◽  
Inverse Correlation ◽  
Hashimoto Thyroiditis ◽  
Case Control ◽  
Control Group ◽  
Autoimmune Hypothyroidism ◽  
Control Study

Abstract Background: Although in many studies, the relationship between autoimmune hypothyroidism (Hashimoto) and Vitamin D deficiency was shown, no research has been performed on the role of vitamin D in non-autoimmune hypothyroidism.Methods: This was a case-control study in Endocrinology clinic of Jahrom (south of Iran). The patients with Hashimoto (n=633) and non-Hashimoto hypothyroidism (n=305), along with a control group (n=200) were evaluated. 25(OH) D level, T3 and T4 levels were studied and Anti TPO and Anti TG tests were performed. The results of vitamin D level were analyzed and interpreted using SPSS in terms of the cause of hypothyroidism (immune and non-immune).Results: The results of the study showed a significantly lower level of vitamin D in both immune and non-immune Hashimoto’s thyroiditis (HT) in comparison to healthy controls (P<0.05). We observed a significant inverse correlation between the vitamin D and TGAb level (p=0.001, r=-0.261) and a direct correlation of vitamin D with TSH level (p=0.008, r=0.108) in Hashimoto thyroiditis patients.Conclusion: Finally, the results indicated that non-autoimmune hypothyroidism, as well as HT, is associated with vitamin D deficiency. The role of vitamin D deficiency in Hashimoto thyroiditis was thought to be in the association of higher autoantibody (TGAb) level; while, there should be further studies determining vitamin D deficiency's role in non-immune hypothyroidism.

scholarly journals Vitamin D Deficiency in Non-Autoimmune Hypothyroidism: A case-control study

2020 ◽  
Author(s):  
Salma Ahi ◽  
Mohammad Reza Dehdar ◽  
Naser Hatami
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Case Control Study ◽  
Inverse Correlation ◽  
Case Control ◽  
Control Group ◽  
Retrospective Case ◽  
Autoimmune Hypothyroidism ◽  
Control Study

Abstract Objectives: Although in many studies, the relationship between autoimmune hypothyroidism (Hashimoto) and Vitamin D deficiency was shown, no research has been performed on the role of vitamin D in non-autoimmune hypothyroidism. Design: This was a Retrospective case–control study in Endocrinology clinic of Jahrom (south of Iran). The patients with Hashimoto (n=633) and non-Hashimoto hypothyroidism (n=305), along with a control group (n=200) were evaluated. 25(OH)D level, T3 and T4 levels were studied and Anti TPO and Anti TG tests were performed. The results of vitamin D level were analyzed and interpreted using SPSS in terms of the cause of hypothyroidism (immune and non-immune). Results: The results of the study showed a significantly lower level of vitamin D in both immune and non-immune Hashimoto’s thyroiditis (HT) in comparison to healthy controls (P<0.05). We observed a significant inverse correlation between the vitamin D and TGAb level (p=0.001, r=-0.261) and a direct correlation of vitamin D with TSH level (p=0.008, r=0.108) in HT patients. Conclusion: Finally, the results indicated that non-autoimmune hypothyroidism, as well as HT, is associated with vitamin D deficiency. The role of vitamin D deficiency in HT was thought to be in the association of higher autoantibody (TGAb) level; while, there should be further studies determining vitamin D deficiency's role in non-immune hypothyroidism.

scholarly journals Correlation of serum vitamin D levels and anemia in childhood pneumonia: a case control study from rural area

2017 ◽  
Vol 4 (3) ◽  
pp. 756
Author(s):  
Suhas P. Kulkarni ◽  
Ashok A. Chougule
Keyword(s):  
Vitamin D ◽  
Case Control Study ◽  
Serum Vitamin ◽  
Case Control ◽  
Control Group ◽  
Immunomodulatory Activity ◽  
Healthy Children ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Control Study

Background: Pneumonia remains number one cause for morbidity and mortality in children. Vitamin D has been shown to have immunomodulatory activity. Hence to find correlation between vitamin D and pneumonia cases the study was carried out.Methods: A case control study was conducted at a rural hospital in Vadgaon. From September 2015 onwards all children under 5 years of age hospitalized with pneumonia were invited to participate in our study. Patients who consented for study underwent serum vitamin 25 (OH) D3 estimation along with other routine investigations as indicated. During the same study period, parents of otherwise healthy children fewer than 5 years age who came to our immunization clinic were invited to participate in the study as a control group.Results: Vitamin 25(OH) D3 levels in pneumonia cases study group (N=40) 12.048±6.015 ng/ml (Mean±SD) and in control (N=35) 22.65±11.77 ng/ml (mean±SD) that is statistically significant (P<0.0001) and hemoglobin (Hb) in Cases (N=40) with 8.55±1.27 gm/dl (mean±SD); control group (N=19) with 10.31±0.9 gm/dl (mean±SD)levels was found to be statistically significant (p < 0.0001).All patients with severe pneumonia needing ICU management were found to be deficient in vitamin D levels. Children with pneumonia had higher level of anemia. All children admitted to ICU had Moderate to severe anemia.Conclusions: There is a correlation between Vitamin D deficiency and severity of pneumonia and there is also correlation between level of anemia and severity of pneumonia.

Vitamin D among Patients of Pulmonary and Extrapulmonary Tuberculosis: A Prospective Case-control Study

2020 ◽  
Vol 16 (1) ◽  
pp. 59-65
Author(s):  
Doaa Gadallah ◽  
Ahmed Sedky ◽  
Hend Mohamed Esmaeel
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Extrapulmonary Tuberculosis ◽  
Serum Levels ◽  
Case Control ◽  
Normal Serum ◽  
Control Group ◽  
Tb Treatment ◽  
Vitamin D Levels ◽  
Control Study

Background: Vitamin D has an essential role in enhancing the immune system to fight and destroy bacteria. People with vitamin D deficiency are highly liable to develop active pulmonary and extrapulmonary tuberculosis. Objective: : To evaluate the serum level of vitamin D among patients with pulmonary and extrapulmonary tuberculosis. Patients and Methods: A case-control prospective study was conducted among patients with pulmonary and extrapulmonary tuberculosis and asymptomatic persons (controls). The study included 80 participants, 50 were TB patients, while 30 were controls. Vitamin D 1, 25(OH) assay was done for all. Results: Vitamin D assay of the included subjects revealed that 52 patients were vitamin D deficient, 7 patients had insufficient vitamin D and 21 had normal serum levels. Of the extrapulmonary TB patients, 35 (100%) had vitamin D deficiency, in pulmonary TB patients, 15 (100%) were vitamin D deficient. While 2 study subjects (6.7%) in the control group were deficient of vitamin D, 7 (23.3%) had insufficient vitamin D and 21cases had normal vitamin D levels. There was a statistically significant relationship between pulmonary and extrapulmonary TB cases and vitamin D deficiency (P< 0.001). Conclusion: Vitamin D deficiency was found among pulmonary and extrapulmonary tuberculosis patients especially among female patients and patients in rural residence. The current study needs additional work to evaluate the value of adding vitamin D to the TB treatment regimen.

scholarly journals Vitamin D Deficiency in Non-Autoimmune Hypothyroidism: A case-control study

2019 ◽  
Author(s):  
Salma Ahi ◽  
Mohammad Reza Dehdar ◽  
Naser Hatami
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Case Control Study ◽  
Inverse Correlation ◽  
Case Control ◽  
Control Group ◽  
Retrospective Case ◽  
Autoimmune Hypothyroidism ◽  
Control Study

Abstract Objectives: Although in many studies, the relationship between autoimmune hypothyroidism (Hashimoto) and Vitamin D deficiency was shown, no research has been performed on the role of vitamin D in non-autoimmune hypothyroidism. Design: This was a Retrospective case–control study in Endocrinology clinic of Jahrom (south of Iran). The patients with Hashimoto (n=633) and non-Hashimoto hypothyroidism (n=305), along with a control group (n=200) were evaluated. 25(OH)D level, T3 and T4 levels were studied and Anti TPO and Anti TG tests were performed. The results of vitamin D level were analyzed and interpreted using SPSS in terms of the cause of hypothyroidism (immune and non-immune). Results: The results of the study showed a significantly lower level of vitamin D in both immune and non-immune Hashimoto’s thyroiditis (HT) in comparison to healthy controls (P<0.05). We observed a significant inverse correlation between the vitamin D and TGAb level (p=0.001, r=-0.261) and a direct correlation of vitamin D with TSH level (p=0.008, r=0.108) in HT patients. Conclusion: Finally, the results indicated that non-autoimmune hypothyroidism, as well as HT, is associated with vitamin D deficiency. The role of vitamin D deficiency in HT was thought to be in the association of higher autoantibody (TGAb) level; while, there should be further studies determining vitamin D deficiency's role in non-immune hypothyroidism.

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