scholarly journals Awareness about thalassemia and feasibility of cascade screening in families of thalassemia major patients

2019 ◽  
Vol 6 (6) ◽  
pp. 2526
Author(s):  
Leeha Singh ◽  
Minal Wade ◽  
Mukesh Agrawal

Background: The main objective of this study is to assess knowledge and attitude of parents & extended relatives of children diagnosed with Thalassemia major and to evaluate feasibility of screening of extended families for thalassemia trait by correlating their willingness to get screened with actual screening.Methods: This was a cross sectional type of descriptive  analytical study, conducted at the thalassemia day care center at a tertiary care teaching hospital in western India among 230 study population using a pre-designed and pre-validated structured questionnaire.Results: We found the overall knowledge score of parents about thalassemia was significantly better than relatives. About 95.83% of parents and only 31.86% of the relatives amongst the study population had adequate knowledge. Majority of study population (84.61% relatives and 100% parents) had positive attitude. The significant contributing factors for knowledge and attitude towards thalassemia were age, marital status, education level, religion and per capita monthly income. 2% relatives agreed to get themselves screened for thalassemia status out of which only 20% got themselves screened.Conclusions: This study has identified key areas which need to be highlighted and emphasized in public awareness campaigns for thalassemia screening in India.

2021 ◽  
Vol 12 (10) ◽  
pp. 92-96
Author(s):  
Shitij Goel ◽  
Shivam Dr ◽  
Azra Ferheen Chaudhary

Background: Dermatophytic infections are one of the most common skin infections encountered by dermatologists. A recent increase in incidence has been seen over the last few years with substantial change in the clinical profile of patients. Recently a group of dermatology experts published Expert Consensus on The Management of Dermatophytosis in India (ECTODERM India). The group agreed upon various definitions with respect to current dermatophytosis epidemic as well as gave recommendations for investigations and management. Clinical profile of dermatophytosis was done in present study on the basis of definitions agreed upon by ECTODERM consensus group. Aims and Objective: To assess the clinical profile, prevalence and severity of dermatophytic infection in study population. Materials and Methods: Cross-sectional observational study was conducted at out-patient department of Dermatology in, Sharda hospital, Greater Noida. A total of 317 patients presenting with clinical diagnosis of dermatophytosis were included in the study. Results: A total of 317 patients were recruited in the study, out of which 213 were males (67.2%). The most common age group presenting with superficial dermatophytosis was 21-30 years. Majority of the patient presented with chronic dermatophytosis with duration more than 6 months (76.6%) while more than 3 lesions of tinea were observed in 76.6% cases. 191 patients (60%) had moderate to severe involvement with more than 3% of BSA involved. Family members presenting with similar complaints were seen in 39% cases. Majority of patients (76 %) studies had received previous treatment topical, systemic or both. 62 patients presented with recurrence of disease within 6 weeks of complete antifungal treatment (19.6%). Conclusion: Our study concludes that dermatophytosis still remain a challenging issue for dermatologists. Chronicity of infection, moderate to severe BSA involvement and involvement of family members in a good proportion of our study cases were the main findings of our study.


Author(s):  
Chirag B. Mistry ◽  
Shreya M. Shah ◽  
Vivek A. Modi ◽  
Suresh D. Mistry

Background: In general, adverse drug reactions (ADRs) are global problems causing both morbidity and mortality. Spontaneous ADR reporting is important to monitor adverse effects of medicines but under reporting is still very prevalent so, there is a need of constant monitoring and rectification of system of Pharmacovigilance. The objective of this study was to evaluate the knowledge, attitude, and practices (KAP) of the healthcare professionals about Pharmacovigilance and to identify the reason for under reporting of ADRs.Methods: A cross-sectional study was carried out using a pretested questionnaire among doctors with minimum qualification MBBS or B.D.S. including faculties, senior and junior residents. Subsequently, analysis of association between education and experience was done by chi square test at P-value <0.05.Results: A pretested questionnaire was distributed among 403 doctors and 240 (59.16%) responded voluntarily. In general, 131 (54.58%) participants noted lack of time to report ADR while 90 (37.50%) participants noted no benefit of reporting already known ADR. On the other hand, total 104 (43.33%) participants were aware about need to report a serious adverse event during “Clinical Trial” within 24 hours to the Ethics Committee. Only 87 (36.25%) participants noted a need of reporting of already known ADR.Conclusions: Participants had good knowledge and attitude towards pharmacovigilance, but the actual practice of ADR reporting is still deficient among them that can be improved by sensitization training and involvement of grass root level health care workers.


Author(s):  
Vamsi Krishna Undavalli ◽  
Praveen M. ◽  
Narni H.

Background: Globally, 51% of stroke (cerebrovascular disease) and 45% of ischaemic heart disease deaths are attributable to high systolic blood pressure. At any given age, the risk of dying from high blood pressure in low- and middle-income countries is more than double that in high-income countries. The objective of the study was to know the prevalence of undiagnosed hypertension among rural population.Methods: A community based cross-sectional study conducted in villages under the rural field practice area of medical college in the month of May, 2017. 365 people participated in the hypertension screening camp constituted the study sample.Results: Prevalence of undiagnosed HTN was found to be 10.1% among study population. Nearly 58.1% of the people are with normal blood pressure while 31.2%, 10.7% of the study population are classified prehypertensive, hypertensives according to JNC- VII.Conclusions: Early detection and treatment of hypertension and other risk factors through Health education programs, public awareness campaigns to be conducted actively among population.


2021 ◽  
pp. 1-2
Author(s):  
Seema Sharma ◽  
Shivani A Patel ◽  
Shivam N Shah ◽  
Mauli P Vora

Aim: To study the clinical and laboratory profile of patients having systemic lupus erythematosus (SLE) at Civil Hospital, Ahmedabad. SLE is an autoimmune multisystem disease which mainly affects young females in their child bearing age leading to decreased productivity and increased economic burden Methods: -Type of study: Cross sectional study. Patients fulfilling revised American College of Rheumatology criteria (1982) for SLE were included in the study. Detailed history, clinical examination and laboratory results of the patients were noted. Data analysis was carried out using Statistical Package for Social Sciences. Results: 25 patients were enrolled in the study. Females (84%) were more commonly affected, maximum patients being in the age group of 20 – 30 years. Arthritis was amongst the commonest initial manifestation (84%) followed by anemia (76%). Other manifestations included involvement of Renal, Cardiopulmonary, Dermatologic and Nervous System. ANA antibody was found positive in all patients while anti dsDNA was positive in 80% patients. Conclusion: The incidence of anemia and lupus nephritis was higher in our study as compared to other studies. Early intervention and close follow up is vital to prevention of morbidity and mortality. Arthritis and Anemia were amongst the most common clinical features.


2018 ◽  
Vol 7 (1) ◽  
pp. 32-39
Author(s):  
D.R. Shakya

Introduction: The knowledge and attitude prevailing during internship of medical education are likely to influence whole career. Psychiatry is seen differently, at times unrealistically. Such views might have adverse consequences. The objective of this study was to assess knowledge and views of intern MBBS doctors of B. P. Koirala Institute of Health Sciences, Nepal about ‘Psychiatry and mental health’. Material and Method: A cross-sectional semi-qualitative survey was done by explaining about the study, distributing a questionnaire and analysing collected samples of the interns. Results: Within study period, 50 respondents participated. Twenty percent respondents were female. One-third subjects were from Kathmandu valley, followed by other cities of Nepal and India. Two-thirds opted psychiatry posting, half to learn about it. About 25% considered psychiatry for career. Majority viewed psychiatry should integrate with other departments. Only few meant mental illness to be unremitting and chronic only, and considered mental patients dangerous and aggressive. More believed that majority of patients understand others’ feelings, attitudes and behavior; and can be productive if treated appropriately. A great majority felt that the management should be multi-sectorial and multi-dimensional. They expressed dissatisfaction about current position of mental health on national health-policy and advised public awareness as the most important step to change the situation. Conclusion: Intern-doctors of a tertiary-care teaching hospital with psychiatry teaching, in overall, have favorable attitude towards psychiatry and mental health.


2019 ◽  
Vol 48 (2) ◽  
pp. 030006051987349
Author(s):  
Witchuwan Onsoi ◽  
Jitjira Chaiyarit ◽  
Leelawadee Techasatian

Objectives Dermatological disorders are common in general pediatric practice. This study aimed to examine common skin problems and the manner in which they tend to be misdiagnosed. Methods A cross-sectional study was conducted from January 2015 to December 2016 using medical record data from the Pediatric Dermatological Outpatient Unit at Khon Kaen University, Faculty of Medicine. Results A total of 1551 visits by 769 patients were documented during the study period. A total of 114 presenting diseases were recorded. The most common skin disease in the study population was dermatitis (unspecified) (88/769, 11.4%), followed by atopic dermatitis (76/769, 9.8%) and infantile hemangioma (72/769, 9.3%). There was a total of 55 (48.2%) misdiagnosed diseases. Some unique cutaneous diseases were undiagnosed because of their rarity. However, the percentages of common cutaneous diseases, such as tinea capitis and molluscum contagiosum, which had been misdiagnosed, were also high (62.50% [95% confidence interval = 24.49–91.48] and 71.43% [95% confidence interval = 29.04–96.33], respectively). Conclusion A large percentage of misdiagnoses of common cutaneous diseases may be due to general pediatricians being undereducated in the field of dermatology. Accurate recognition and appropriate management of these conditions should be emphasized for educating general pediatricians in the future.


2017 ◽  
Vol 24 (06) ◽  
pp. 904-911
Author(s):  
Syed Rizwan Ali Bokhari ◽  
Syed Arsalan Khalid ◽  
Nida Nadeem ◽  
Sidra Saleem ◽  
Zumar Sardar ◽  
...  

Background: Acute kidney injury (AKI) in pregnant women is commonly seen indeveloping countries. It is associated with significant morbidity, social and personal implications.We conducted a study to assess the prevalence and severity of depression in patients withpregnancy related AKI (PRAKI) in a tertiary care center. Methodology: Patients with PRAKIadmitted from 1-16 to 6-16 under Nephrology service, Jinnah Hospital, Lahore were included inthis cross-sectional study. The Hamilton Rating scale for depression (HAM-D) version translatedand adapted in Urdu, was used to assess the study population. These patients were interviewedwith the HAM-D questionnaire on their first encounter with Nephrology department. Previoushistory of psychiatric illness was excluded. The diagnosis of AKI was based on the classificationof the Acute Kidney Injury Network group. Results: The mean age of the patients was 24±5years. Seventeen (57%) patients were multipara and 13(43%) patients were primigravida. Of the30 patients with AKI, 8 (27%) presented before 28 weeks and 22 (63%) presented after 28 weeksof gestation. The causes of AKI included postpartum hemorrhage in 9 (30%), sepsis in 8 (27%),preeclampsia/eclampsia in 6(20%), shock in 4 (13%) and coagulopathy in 3 (10%) patients.Alive and healthy fetus was found in only 15 (50%) patients. Twenty-one (70%) patients receivedaverage of 5-8 hemodialysis sessions during their hospital stay. Twenty-three (76%) had nodepression (0-7 score), 2 (7%) had mild (8-13 score), 3 (10%) had moderate (14-18 score) and2 (7%) had severe (19-22 score) depression according to HAM-D score. Conclusions: Ourstudy depicted considerable depression of varying degrees in women with PRAKI, increasedawareness and effective monitoring for depression should be integrated into regular maternalcare to decrease morbidity associated with it.


2003 ◽  
Vol 42 (145) ◽  
pp. 27-31 ◽  
Author(s):  
Pramod M. Shyangwa ◽  
S Singh ◽  
S K Khandelwal

ABSTRACTThe magnitude of mental health problem is cosiderable. However the attitude of the general public towardsmental illness and mentally ill people is largely negative. Perception and knowledge of the nursing staff onthis topic is important as they directly deal with patients and their relatives, and they are also involved indisseminating health information. A negative attitude is known hindrance to providing quality service tomentally or physically ill persons. This study, therefore, carried out among nursing staff at B. P. KoiralaInstitute of Health Sciences (BPKIHS) a tertiary care center in Nepal, aims to find out nurses’ knowledgeand attitude about mental illness.It is a cross-sectional, descriptive study with 110 respondents, who were predominantly females (97.27%)and young (mean age=25.7year). The study revealed some interesting findings as many of the participantsthought mentally ill people are ‘ insane’ (37.5%). The majority had showed their knowledge about causes ofmental illness as genetic or inherited (65.4%) and biochemical disturbances (90.0%). About three fourthwere ready to work together (71.8%) and chat with them (91.8%). Respondents expressed their faith inpsychiatrists (93.5%) but less in faith healers (3.0%). The vast majority had obtained information aboutmental illness from ‘seeing mentally ill persons’ (94.0%) followed by communication with medical personnel(84.5%). This study revealed that there was overall adequate knowledge and by and large a positive attitude.Key Words: Mental health, nurses, knowledge, attitude, Nepal.


2017 ◽  
Vol 8 (2) ◽  
pp. 44-49
Author(s):  
Iyshwarya Udaya Kumar ◽  
Jaya Prakash Murthy ◽  
Ujwal Upadya ◽  
Mahesh Venkatesh

Background: Diabetes Mellitus is a chronic disorder, which is becoming rapidly epidemic in India.There are many complications occur due to uncontrolled diabetes mellitus.The outcome of diabetes depends mainly on the patient’s self-management like health-related behavior, which is based on his or her knowledge. Awareness on diabetes mellitus is still a lacunae among the Indian population.Aims and Objective: To determine the knowledge regarding awareness of diabetes like the risk factors, symptoms, complications and the management among the males and females in rural population.Materials and Methods: It is a cross sectional study conducted at the tertiary care center in rural Bangalore. A structured questionnaire was used and 300 adults were assessed on their knowledge regarding the awareness of diabetes.Result: Out of 300 adults, 159 adults (53%) had a history of diabetes. There was no gender difference observed regarding the awareness, nor the education played a role. There was significant difference observed in knowledge of diabetes Mellitus among the diabetics with respect to renal complications (p <0.013), symptoms like blurring of vision (p < 0.043) and burning feet (p < 0.009).Conclusion: Both the diabetic and non-diabetic groups had very low awareness regarding diabetes and associated risk factors. Both Males and females awareness levels were poor. Proper Diabetic education programme will help in raising public awareness of the disease.Asian Journal of Medical Sciences Vol.8(2) 2017 44-49


2021 ◽  
Vol 28 (05) ◽  
pp. 635-639
Author(s):  
Syed Maroof Hashmi ◽  
Arif Raza ◽  
Shiraz Ahmed Gauri ◽  
Ramesh Kumar ◽  
Syed Muneeb Younus

Objective: To assess the outcome of mild traumatic brain injury patients who have isolated intracranial hemorrhages. Study Design: Cross-sectional, Setting: Department of Neurosurgery, Abbasi Shaheed Hospital, Karachi. Period: 1st January 2018 to 31st January 2020. Material & Methods: The inclusion criteria were that all the patients have to be above the age of 18 years, presented to us with mild TBI cases and had observable intracranial hemorrhage on computer tomography (CT) scan. Patient demographics and the various types of interventions were recorded. Results: A total of n= 300 patients were included in the study, The average age was 50.5 +/- 20.6 years. There were n= 180 males and n= 120 females. We performed a total of n= 45 (15%) neurosurgical interventions, the most common intervention being craniotomies performed in n= 31 (68.66%) patients. Of all the patients who underwent an intervention 64.44% had immediate intervention 20% had planned intervention as non-emergency cases, and 15.55% had delayed intervention. A one point increment in the GCS score is associated with 50% lower odds of surgical intervention having a p value of <0.001. The mortality rate in our study population was 6%.  Conclusion: We found that the length of stay and mortality are associated with an increased age and lower GCS score of the patients, care should be taken when evaluating the patients as some cases require delayed intervention hence monitoring is of prime importance.


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