scholarly journals Role of platelet-rich plasma in maxillofacial surgery

2021 ◽  
Author(s):  
Sara Ahmed Hifny ◽  
Abdullrahman Saeed Alalharith ◽  
Mutasim Ahmad Idrees ◽  
Mohammed Ahmed Befle ◽  
Shihnaz Mohammed AlGarni ◽  
...  
Keyword(s):  
Wound Healing ◽  
Oral Surgery ◽  
Platelet Rich Plasma ◽  
Maxillofacial Surgery ◽  
Neck Surgery ◽  
Medical Settings ◽  
Osseointegrated Implants ◽  
Literature Evidence ◽  
Periodontal Plastic Surgery

Platelet-rich plasma (PRP) has been reported as an efficacious modality that can enhance the process of wound healing and tissue regeneration and has been validated in different medical settings, including cardiovascular surgery, otolaryngology, head and neck surgery, and maxillofacial surgery. In dental and oral surgery settings, PRP has been reported as an efficacious approach with favorable outcomes in different settings. Some of these procedures include surgical repair of the alveolar cleft, mandibular reconstruction, ablative surgical procedures, placement of osseointegrated implants, periodontal plastic surgery, and management of infrabony periodontal defects. In the present study, we aim to discuss the role and mechanisms that PRP plays in the settings of maxillofacial surgery based on evidence from the relevant studies in the literature. Evidence indicates the wide acceptance of the modality, which has been proven to increase the rate of wound healing and reduce the frequency of pain and swelling. The administration of PRP has been reported to dispense with the need for invasive approaches that might be furtherly associated with complications and different morbidities. However, in most of the favorable events where the PRP administration of was associated with enhanced outcomes, the modality was used in combination with another therapeutic approach. Therefore, further research is needed to validate the efficacy of the modality in the different settings.

Use of Platelet-Rich Plasma and Platelet-Rich Fibrin in Dentistry and Oral Surgery: Introduction and Review of the Literature

2019 ◽  
Vol 36 (2) ◽  
pp. 109-123 ◽  
Author(s):  
Kristina Feigin ◽  
Bonnie Shope
Keyword(s):  
Soft Tissues ◽  
Oral Surgery ◽  
Platelet Rich Plasma ◽  
Maxillofacial Surgery ◽  
Oral And Maxillofacial Surgery ◽  
Platelet Concentrates ◽  
Platelet Rich Fibrin ◽  
Wide Range ◽  
Comprehensive Examination ◽  
And Function

Platelet concentrates, mostly represented by platelet-rich plasma and platelet-rich fibrin, have gained significant interest in various medical and oral disciplines because of their potential to stimulate and boost regeneration of hard and soft tissues. Prepared from the patient’s own blood, they have been tested and used in various different surgical fields including oral and maxillofacial surgery. The effects of these biomaterials are described to be a result of the large concentration of platelets which contain a wide range of growth factors. The aim of this article is to introduce the principle and function of these platelet concentrates, to review their preparation, and to provide a comprehensive examination of the published oral and maxillofacial literature on this subject.

scholarly journals Platelet Rich Plasma: a short overview of certain bioactive components

Open Medicine ◽  
2016 ◽  
Vol 11 (1) ◽  
pp. 242-247 ◽  
Author(s):  
Voja Pavlovic ◽  
Milan Ciric ◽  
Vladimir Jovanovic ◽  
Predrag Stojanovic
Keyword(s):  
Wound Healing ◽  
Reference Data ◽  
Platelet Rich Plasma ◽  
Physiological Role ◽  
Potential Effect ◽  
Bioactive Components ◽  
Bioactive Substances ◽  
New Approach ◽  
Different Tissues

AbstractPlatelet rich plasma (PRP) represents a relatively new approach in regenerative medicine. It is obtained from patient’s own blood and contains different growth factors and other biomolecules necessary for wound healing. Since there are various protocols for PRP preparing, it usually results with PRP generation with different amounts of bioactive substances, which finally may modulate the intensity of wound healing. The reference data about potential effect of some PRP compounds on wound healing, in different tissues, are still controversial. This review summarizes recently known facts about physiological role of certain PRP components and guidance for further research. Also, this review discusses different procedure for PRP generation and potential effect of leukocytes on wound healing.

scholarly journals The Role of Chemical Agents in the Microbial Flora with Major Risk of Interventios in Maxilo-facial Surgery

2019 ◽  
Vol 70 (6) ◽  
pp. 1988-1991
Author(s):  
Carmen Gabriela Stelea ◽  
Iulian Constantin ◽  
Cristian Budacu ◽  
Alexandra Lorina Platon ◽  
Mihail Balan ◽  
...  
Keyword(s):  
Oral Surgery ◽  
Maxillofacial Surgery ◽  
The Body ◽  
Small Scale ◽  
Oral And Maxillofacial Surgery ◽  
Periodontal Surgery ◽  
Facial Surgery ◽  
Chemical Agents ◽  
Infectious Etiology

The pathology of the oro-maxilo-facial territory comprises a vast chapter of diseases with primary or secondary infectious etiology, the mouth being the natural cavity of the organism with the most varied and variable flora of bacterial contamination. By the continuity solutions created by the mechanical act of mastication, decubitus of defective prosthetic works, local dento-periodontal infectious processes, but especially of dental or small-scale interventions, open gates and possibilities of penetration into the blood circulation of the microorganisms, which cause the transient bacteria. The study included 243 randomly selected patients, with the address of the Oral and Maxillofacial Surgery Clinic in the period 2016-2018. The inoculation of microorganisms in the oral cavity in circulating blood as a result of oral surgery or dental care procedures is much more common than in other areas of the body. Aggressive dental maneuvers that create solutions of continuity of oral mucosa, gingiva, periodontal surgery, periodontal surgery techniques can cause bacteria.

Role of Bovine Fetal Platelet-rich Plasma (PRP) on Skin Wound Healing in Mice

2019 ◽  
Vol 16 (1) ◽  
pp. 18-26
Author(s):  
Mardin O. Mohammed ◽  
Osman J. Ali ◽  
Sozan A. Muhamad ◽  
Salam H. Ibrahim ◽  
Goran M. Raouf ◽  
...  
Keyword(s):  
Wound Healing ◽  
Platelet Rich Plasma ◽  
Skin Wound ◽  
Skin Wound Healing

scholarly journals THE EMERGING ROLE OF SERRATIOPEPTIDASE IN ORAL SURGERY: LITERATURE UPDATE

2018 ◽  
Vol 11 (3) ◽  
pp. 19 ◽  
Author(s):  
Santhosh Kumar Mp
Keyword(s):  
Proteolytic Enzyme ◽  
Therapeutic Agent ◽  
Oral Surgery ◽  
Maxillofacial Surgery ◽  
Oral And Maxillofacial Surgery ◽  
Medical Field ◽  
Enzyme Preparations ◽  
Inflammatory Agent ◽  
Anti Inflammatory

 Serratiopeptidase, a proteolytic enzyme derived from Serratia E-15 species enterobacteria, is widely used in medical field for its anti-inflammatory, anti-edemic properties, and analgesic properties. It is being used commonly in various specialties such as orthopedics, otolaryngology, gynecology, surgery, pulmonology, ophthalmology, and dentistry. Research has shown that serratiopeptidase is the most effective anti-inflammatory agent compared to other enzyme preparations. This article reviews the efficacy, safety, and applications of serratiopeptidase in oral surgery. This article also discusses the mechanism of action of serratiopeptidase, its contraindications and complications. From the recently published literature, it is clear that the role of serratiopeptidase as a therapeutic agent in oral and maxillofacial surgery is expanding and they hold a promising future as a broad-spectrum anti-inflammatory drug with minimal side effects and complications. Further, research will broaden their applications in the field of medicine and dentistry.

The Role of “Eye Platelet Rich Plasma” (E-Prp) for Wound Healing in Ophthalmology

2012 ◽  
Vol 13 (7) ◽  
pp. 1257-1265 ◽  
Author(s):  
Jorge L. Alio ◽  
Francisco Arnalich-Montiel ◽  
Alejandra E. Rodriguez
Keyword(s):  
Wound Healing ◽  
Platelet Rich Plasma
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