A prospective study of demography, clinical presentation and risk factors of cerebral venous thrombosis in pregnant and postpartum women

2019 ◽  
Vol 6 (1) ◽  
pp. 29-32
Author(s):  
Neelam Singh ◽  
◽  
Sonal Kulshreshtha ◽  
Dinesh Udainiya ◽  
Jyoti Bindal ◽  
...  
Keyword(s):  
Risk Factors ◽  
Prospective Study ◽  
Venous Thrombosis ◽  
Cerebral Venous Thrombosis ◽  
Clinical Presentation ◽  
Postpartum Women ◽  
A Prospective Study

scholarly journals Neuropathic Pain in Children with Sickle Cell Disease: The Hidden Side of the Vaso-Occlusive Crisis

Children ◽  
2021 ◽  
Vol 8 (2) ◽  
pp. 84
Author(s):  
Jeanne Sigalla ◽  
Nathalie Duparc Alegria ◽  
Enora Le Roux ◽  
Artemis Toumazi ◽  
Anne-Françoise Thiollier ◽  
...  
Keyword(s):  
Risk Factors ◽  
Neuropathic Pain ◽  
Sickle Cell Disease ◽  
Sex Ratio ◽  
Prospective Study ◽  
Sickle Cell ◽  
Clinical Presentation ◽  
Early Stage ◽  
Cell Disease ◽  
A Prospective Study

The majority of hospitalizations of patients with sickle cell disease (SCD) are related to painful vaso-occlusive crises (VOCs). Although the pain of VOC is classically nociceptive, neuropathic pain (NP) has also been demonstrated in SCD patients. The aim of our study is to specify the prevalence of NP during VOCs in SCD children using a dedicated scale and to measure its characteristics. We performed a prospective study that included SCD children hospitalized for an acute VOC. The presence of NP was sought with the DN4 scale on the second and fourth days of hospitalization. A total of 54 SCD children were included in the study. Overall, 41% of the patients (n = 22) experienced neuropathic pain during the VOC, mostly at an early stage (Day 2). The median age, the sex ratio, the location of the pain, and the morphine consumption were similar for patients with and without NP. Our study shows that neuropathic pain is very common during VOCs in SCD children. The absence of identified risk factors should prompt us to be vigilant regardless of the patient’s age, sex, and clinical presentation.

Prognostic indices for cerebral venous thrombosis on CT perfusion: A prospective study

2014 ◽  
Vol 83 (1) ◽  
pp. 185-190 ◽  
Author(s):  
Rakesh Kumar Gupta ◽  
J.R. Bapuraj ◽  
N. Khandelwal ◽  
Dheeraj Khurana
Keyword(s):  
Prospective Study ◽  
Venous Thrombosis ◽  
Cerebral Venous Thrombosis ◽  
Ct Perfusion ◽  
Prognostic Indices ◽  
A Prospective Study

scholarly journals Evaluation of cerebral venous thrombosis by computed tomography/MRI and magnetic resonance venography in pregnant and postpartum women: a prospective study

2018 ◽  
Vol 6 (10) ◽  
pp. 3381
Author(s):  
Neelam Singh ◽  
Dinesh Udainiya ◽  
Sonal Kulshreshtha ◽  
Jyoti Bindal
Keyword(s):  
Venous Thrombosis ◽  
Temporal Lobe ◽  
Cerebral Venous Thrombosis ◽  
Post Partum ◽  
Transverse Sinus ◽  
Venous System ◽  
Postpartum Women ◽  
Hemorrhagic Infarction ◽  
Sagittal Sinus ◽  
A Prospective Study

Background: Diagnosis of Cerebral venous thrombosis (CVT) is challenging as it is an uncommon cause of stroke with varied clinical presentations, predisposing factors, imaging findings, and outcomes. Prompt and accurate diagnosis is important for timely intervention in order to reverse and significantly reduce the acute and long-term sequel. Aims and objectives was to study cerebral venous thrombosis in pregnant and post-partum women.Methods: Hundred pregnant and postpartum women having CVT were studied at Kamla Raja Hospital and JA Group of Hospital at GR Medical College, Gwalior Madhya Pradesh for study period of 2016 to 2017. All the women had undergone CT/MRI and MRV.Results: Age of CVT patients ranged from 18-35 years with a maximum incidence (84%) in the 2nd decade (20-30 years). Sixty two percent women had infarction; out of that 53% had hemorrhagic infarction. Frontal lobe (10%) and temporal lobe (10%) were more affected. Superior sagittal sinus (SSS) was most commonly involved (71%) followed by transverse sinus (66%) and sigmoid sinus (45%). Superficial venous system was involved in 32 patients while deep venous system was involved in 20 patients. Majority of (82%) patients had combination of sinuses and venous involvement.Conclusions: CVT was more prevalent in young pregnant and postpartum women. Hemorrhagic infarction were common and affecting frontal and temporal lobe. SSS were mostly affected in CVT. MRV should be the first line diagnostic tool for diagnosis of CVT in pregnant and postpartum women.

Abstract 3920: Epilepsy as a Long-Term Complication After Cerebral Venous Thrombosis

Stroke ◽  
2012 ◽  
Vol 43 (suppl_1) ◽  
Author(s):  
Carlos Cantu-Brito ◽  
Erwin Chiquete ◽  
Antonio Arauz ◽  
Marlon Merloz-Benitez
Keyword(s):  
Risk Factors ◽  
Venous Thrombosis ◽  
Cerebral Venous Thrombosis ◽  
Clinical Presentation ◽  
Thrombotic Event ◽  
Long Run ◽  
Increased Risk ◽  
Long Term Follow Up

Background. Seizures is a very common clinical presentation of cerebral venous thrombosis (CVT); however, little is known about the future risk of epilepsy in patients suffering CVT. Our objective was to analyze risk factors for epilepsy in a long-term follow-up after CVT. Methods. This is a cohort descriptive study of consecutive non-selected patients with acute cerebrovascular disease, systematically registered from 1986 to 2010 in a third-level referral center of Mexico City. Here we analyzed 340 patients who survived the first 6 months after CVT, who were not epileptic at baseline and for whom complete long-term information on neurological outcome was available. Results. Seizures occurred in 183 (54%) patients, in 26% of them as a clinical presentation and 74% at some point during follow-up. Focal motor seizures occurred in 6.5%, secondary generalized focal seizures in 13.8% and generalized tonic-clonic seizures in 22.4%. Status epilepticus occurred in 13 (7%) cases. In all, during a median follow-up of 28 months (range 2 to 288 months), epilepsy was present in 14.7% (27.3% of those who presented seizures). In a multivariate analysis adjusted for multiple confounders, risk factors associated with an increased risk of epilepsy during follow-up were presenting seizures as a clinical presentation [odds ratio (OR): 4.32, 95% confidence interval (CI): 2.20-8.48], pregnancy and puerperium (OR: 2.03, 95% CI: 1.11-3.71) and thrombosis of the longitudinal sinus (OR: 1.86, 95% CI: 1.01-3.41). Conclusion. Seizures are common at CVT presentation, but risk increases during the acute phase after thrombotic event. Most seizures resolve during the first month, but epilepsy occurred in 15% of patients with CVT in the long run.

scholarly journals Headache as the sole presentation of cerebral venous thrombosis: a prospective study

2012 ◽  
Vol 13 (6) ◽  
pp. 487-490 ◽  
Author(s):  
Ângela Timóteo ◽  
Nuno Inácio ◽  
Sara Machado ◽  
Ana Amélia Pinto ◽  
Elsa Parreira
Keyword(s):  
Prospective Study ◽  
Venous Thrombosis ◽  
Cerebral Venous Thrombosis ◽  
A Prospective Study

scholarly journals Genetic Screening of Cerebral Venous Thrombosis Susceptible Women, an Effective Step in Identifying Women at Risk for Obstetric CVT

2021 ◽  
Author(s):  
Khalil Khashei Varnamkhasti
Keyword(s):  
Risk Factors ◽  
At Risk ◽  
High Risk ◽  
Venous Thrombosis ◽  
Genetic Variants ◽  
Genetic Screening ◽  
Cerebral Venous Thrombosis ◽  
Genetic Basis ◽  
Clinical Presentation

Introduction: Predisposition to cerebral venous thrombosis (CVT) also has a genetic basis and inherited thrombophilias constitute 22.4 % of the CVT cases. CVT with a varied clinical presentation and pathogenesis is one of the important causes of stroke which is not very common. Inherited thrombophilias with concomitant acquired risk factors like pregnancy may increase the risk of CVT manifold. Identification of a number of genetic variants increasing susceptibility to CVT and related traits opened up opportunity, to screening of women at high risk of developing obstetric CVT.  

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