scholarly journals To evaluate ocular manifestations in primary hypertension

2021 ◽  
Vol 7 (2) ◽  
pp. 200-203
Author(s):  
Durgesh Kumar Sinha ◽  
Rani Sujatha MA
Keyword(s):  
Blood Pressure ◽  
Severe Hypertension ◽  
Retrospective Chart Review ◽  
Tertiary Hospital ◽  
Ophthalmological Examination ◽  
Hard Exudates ◽  
Ocular Manifestations ◽  
Progression Of Disease ◽  
Irregular Reflection ◽  
Arteriolar Narrowing

To evaluate ocular manifestations in primary severe hypertension.: A retrospective chart review of 100 eyes of 50 patients in age group 45-60 years diagnosed with primary severe hypertension (systolic blood pressure [SBP] ≥ 180 mm Hg and diastolic blood pressure [DBP] ≥ 110 mm of Hg) in a tertiary hospital in 6 months from December 2018 to May 2019. Vision with evaluated with Snellen’s chart, fundus was examined with IDO, DO, +90D, +20 D lens and OCT was done.: Mean age were found to be 51 years ±9.8 under treatment for essential hypertension. Fundus findings included Arteriolar Narrowing (both Focal and Generalized arteriolar Narrowing), Hard Exudates, Cotton Wool Patches, Flame Shaped Haemorrhages, Optic disc edema, Disc haemorrhages. OCT findings included Macular Oedema, Irregular reflection, Sub Retinal Fluid, Inner Retinal Fluid, Hyper Reflective Dots.: This study can be used as an early diagnostic tool in hypertension. Severe hypertension may lead to may exudative changes. With Arteriolar Narrowing and Hyperreflective Dots within retina as the most common findings. Awareness should be spread regarding ophthalmological examination among patients so that timely measures can be initiated to stop the progression of disease.

scholarly journals The Long-term Relation among Retinal Arteriolar Narrowing, Blood Pressure, and Incident Severe Hypertension

2008 ◽  
Vol 168 (1) ◽  
pp. 80-88 ◽  
Author(s):  
J. J. Wang ◽  
E. Rochtchina ◽  
G. Liew ◽  
A. G. Tan ◽  
T. Y. Wong ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Severe Hypertension ◽  
Term Relation ◽  
Arteriolar Narrowing ◽  
Retinal Arteriolar

scholarly journals Anaemic retinopathy in megaloblastic anaemia

2020 ◽  
Vol 12 (2) ◽  
pp. 313-316
Author(s):  
Pradeep Pakalapati ◽  
Afrin Shanwaz
Keyword(s):  
Megaloblastic Anaemia ◽  
Ophthalmological Examination ◽  
Ocular Manifestations ◽  
Cotton Wool Spots ◽  
Corrected Visual Acuity ◽  
Progression Of Disease ◽  
Haematological Disorders ◽  
Systemic Examination ◽  
The Right ◽  
Optic Discs

Introduction: Anaemias are the commonest haematological disorders which cause ocular manifestations. With the progression of disease, retinal haemorrhages, dilated and tortuous veins, cotton wool spots may occur in the ocular fundus. Case: An 18-year-old female patient presented to our out patient department with the sudden, painless, non-progressive blurring of vision in both eyes (best-corrected visual acuity in the right eye is 6/60, and left eye is 6/36) for two days. On Ophthalmological examination, bilateral pale tarsal conjunctiva, yellowish discolouration of the sclera, hyperemic optic discs, macular haemorrhages, superficial and deep haemorrhages with Roth spots were observed. The haematological evaluation showed the presence of Megaloblastic anaemia (with haemoglobin - 2.5g%). There was severe pallor on general examination. Mild hepatomegaly and splenomegaly were noted on the systemic examination and confirmed by ultrasound abdomen. Intraocular pressure was 11 mmHg in both eyes. Conclusion: This case documents the occurrence of bilateral macular haemorrhages and Roth spots in megaloblastic anaemia without thrombocytopenia. Other causes of Roth spots were excluded. Treatment of anaemia showed resolution of Roth spots.

scholarly journals A STUDY ON IV LABETALOL VERSUS ORAL NIFEDIPINE IN ACUTE CONTROL OF SEVERE HYPERTENSION IN PREGNANCY

2020 ◽  
pp. 1-4
Author(s):  
G. Kesava Chand ◽  
Sireesha Ratal
Keyword(s):  
Blood Pressure ◽  
Severe Hypertension ◽  
Tertiary Hospital ◽  
Target Blood Pressure ◽  
10Mg Tablet ◽  
Hypertension In Pregnancy ◽  
Group 5 ◽  
Double Blinded ◽  
To Receive ◽  
In Pregnancy

Objective: To compare the efficacy of IV Labetalol with oral Nifedipine in the treatment of severe hypertension in pregnancy with blood pressure >160/110mm Hg. Methods:A parallel double blinded randomized control trial between Jan 2019 and May 2019 in 100 antenatal women of gestational age>28 weeks, admitted with blood pressure >160/110 mm Hg conducted in labour ward tertiary hospital. Antenatal women were randomized to receive oral Nifedipine 10mg tablet orally up to 5 doses and IV Labetalol was initiated at 20mg and in escalating doses of 20mg, 40mg.80mg, and 80mg up to 220mg. The number of doses and meantime taken to achieve target blood pressure <140/90 mm Hg was noted. Results:hundred antenatal women were randomized to 50 in each group.In the Labetalol group 5 patients required oral Nifedipine to achieve target blood pressure but none in the Nifedipine group. The numbers of doses required and meantime taken to achieve target bloodpressure in nefidipine group were less compared to that of Labetalol group. Conclusion: IV Labetalol and oral Nifedipine were equally effectively to achieve target blood pressure.Incomparsion, oral Nifedipine achieved target blood pressure more quickly than Labetalo

Effects of Antihypertensive Therapy on Blood Pressure and Left Ventricular Hypertrophy in Patients with Severe Hypertension.

2000 ◽  
Vol 41 (3) ◽  
pp. 339-348
Author(s):  
Sumino Hiroyuki ◽  
Nakamura Tetsuya ◽  
Kanda Tsugiyasu ◽  
Sakamaki Tetsuo ◽  
Sato Kunio ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Left Ventricular Hypertrophy ◽  
Antihypertensive Therapy ◽  
Ventricular Hypertrophy ◽  
Severe Hypertension ◽  
Left Ventricular

scholarly journals Evaluation of a collaborative VA network initiative to reduce racial disparities in blood pressure control among veterans with severe hypertension

Healthcare ◽  
2021 ◽  
Vol 8 ◽  
pp. 100485
Author(s):  
Kelly H. Burkitt ◽  
Keri L. Rodriguez ◽  
Maria K. Mor ◽  
Michael J. Fine ◽  
Walter J. Clark ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Racial Disparities ◽  
Blood Pressure Control ◽  
Severe Hypertension ◽  
Pressure Control

scholarly journals 1631. Mycobacterium septicum: A 6-year Clinical Experience from a Tertiary Hospital and Reference Laboratory

2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S807-S807
Author(s):  
John Raymond U Go ◽  
Cristina G Corsini Campioli ◽  
Omar Abu Saleh ◽  
John Wilson ◽  
Sharon Deml ◽  
...  
Keyword(s):  
Lung Disease ◽  
Treatment Duration ◽  
Retrospective Chart Review ◽  
Patient Characteristics ◽  
Tertiary Hospital ◽  
High Rate ◽  
Clinical Microbiology Laboratory ◽  
Reference Laboratory ◽  
Peritoneal Dialysis Catheter ◽  
Increased Risk

Abstract Background Mycobacterium septicum is a rapidly growing non-tuberculous mycobacterium. It is a ubiquitous organism capable of causing infections in both healthy and immunocompromised individuals. Only a few cases have been reported to date, and standard therapeutic regimens, and optimal treatment duration have not been defined. Methods We conducted a retrospective chart review of all patients seen at Mayo Clinic in Rochester, MN from July 2014 to March 2020 from whom Mycobacterium septicum was isolated in culture by our clinical microbiology laboratory. Results There were 12 patients identified with M. septicum infection – 7 males and 5 females. The average age was 67 years, with an age range of 48 to 80 years. Seven of 12 isolates obtained were from sputum samples. Only one patient was on immunosuppressive medication. Three cases were considered clinically significant infections for which directed anti-mycobacterial therapy was instituted. In two of these three cases, co-infection with Mycobacterium avium complex (MAC) was seen. Underlying structural lung disease was present in the two cases of pulmonary infections. Peritoneal dialysis catheter-related peritonitis was seen in the third case. All the isolates were susceptible to amikacin, ciprofloxacin, imipenem, linezolid, moxifloxacin, and trimethoprim-sulfamethoxazole (TMP-SMX). The isolates were resistant to clarithromycin and doxycycline. Patient Characteristics, Associated M. septicum Illness, and Therapy Provided Antimicrobial Susceptibility Profiles of the Mycobacterium septicum Isolates, MIC (mcg/mL) and Interpretation Patient Demographics and Specimen Source of Mycobacerium septicum Isolates Conclusion M. septicum is an unusual cause of non-tuberculous mycobacterial infection. The presence of a foreign body may increase the risk of infection. Individuals with underlying structural lung disease are also likely to be at increased risk of developing pulmonary infection. Generalized treatment recommendations are limited by the lack of prospective controlled trials; hence, optimal antibiotic regimen and treatment duration have not been firmly established. Susceptibility testing should be performed to guide treatment selection, but the use of combination therapy with potentially empiric agents like amikacin, ciprofloxacin, imipenem, linezolid, moxifloxacin, and TMP-SMX as demonstrated in this small study, can be considered. A high rate of macrolide resistance was noted in our study. Disclosures All Authors: No reported disclosures

Late endoscopic evaluation of the ostium size after external dacryocystorhinostomy

2020 ◽  
pp. 112067212097604
Author(s):  
Reem R Al Huthail ◽  
Yasser H Al-Faky
Keyword(s):  
Chart Review ◽  
Retrospective Chart Review ◽  
Tertiary Hospital ◽  
Nasal Endoscope ◽  
Long Term Follow Up ◽  
Mean Size ◽  
External Dacryocystorhinostomy ◽  
The Mean

Objective: To evaluate the effect of chronicity on the size of the ostium after external dacryocystorhinostomy (DCR) with intubation. Methods: Design: A retrospective chart review of patients who underwent external DCR with intubation over 10 years from January 2003 at a tertiary hospital. All patients were recruited and examined with rigid nasal endoscope. Results: A total number of 66 (85 eyes) patients were included. The mean age at the time of evaluation was 53.1 years with gender distribution of 54 females (81.8 %). The mean duration ±SD between the date of surgery and the date of evaluation was 33.2 ± 33.6 (6–118 months). Our study showed an overall anatomical and functional success of 98.8% and 95.3%, respectively. The mean size of the ostium (±SD) was 23.0 (±15.7) mm2 (ranging from 1 to 80.4 mm2). The size of the ostium was not a significant factor for failure ( p = 0.907). No statistically significant correlation was found between the long-term duration after surgery and the size of the ostium ( R: 0.025, p = 0.157). Conclusions: Nasal endoscopy after DCR is valuable in evaluating the ostium with no observed potential correlation between the long-term follow-up after surgery and the size of the ostium.

scholarly journals Bilateral Serous Retinal Detachments Associated with Accelerated Hypertensive Choroidopathy

2010 ◽  
Vol 2010 ◽  
pp. 1-4 ◽  
Author(s):  
Yoshio Hirano ◽  
Tsutomu Yasukawa ◽  
Yuichiro Ogura
Keyword(s):  
Blood Pressure ◽  
Visual Acuity ◽  
Antihypertensive Treatment ◽  
Vascular Tortuosity ◽  
Arteriolar Narrowing ◽  
Hypertensive Choroidopathy ◽  
Retinal Arteriolar

Purpose. We report a case of hypertensive choroidopathy with bilateral serous retinal detachments.Patient. A 50-year-old man underwent bilateral serous retinal detachments. Retinal arteriolar narrowing, vascular tortuosity, and arteriovenous nicking were identified in both eyes. The blood pressure was 206/125 mmHg. The patient was diagnosed with bilateral hypertensive choroidopathy and treated with oral antihypertensive treatment.Results and discussion. One month after antihypertensive treatment, the serous retinal detachments resolved and the visual acuity improved. A patient with those findings should be considered as having hypertensive choroidopathy and treated as soon as possible.

Effect of minoxidil on blood pressure and hemodynamics in severe hypertension

1977 ◽  
Vol 39 (6) ◽  
pp. 796-801 ◽  
Author(s):  
R. Kent Bryan ◽  
Sibley W. Hoobler ◽  
Jonathan Rosenzweig ◽  
John M. Weller ◽  
Janice M. Purdy
Keyword(s):  
Blood Pressure ◽  
Severe Hypertension

scholarly journals Prevalence of amblyopia and patterns of refractive error in the amblyopic children of a tertiary eye care center of Nepal

2013 ◽  
Vol 5 (1) ◽  
pp. 38-44 ◽  
Author(s):  
K Sapkota ◽  
A Pirouzian ◽  
NS Matta
Keyword(s):  
Visual Acuity ◽  
Refractive Error ◽  
Chart Review ◽  
Care Center ◽  
Retrospective Chart Review ◽  
Ophthalmological Examination ◽  
Eye Care ◽  
Common Cause ◽  
Ocular Pathology ◽  
The Mean

Introduction: Refractive error is a common cause of amblyopia. Objective: To determine prevalence of amblyopia and the pattern and the types of refractive error in children with amblyopia in a tertiary eye hospital of Nepal. Materials and methods: A retrospective chart review of children diagnosed with amblyopia in the Nepal Eye Hospital (NEH) from July 2006 to June 2011 was conducted. Children of age 13+ or who had any ocular pathology were excluded. Cycloplegic refraction and an ophthalmological examination was performed for all children. The pattern of refractive error and the association between types of refractive error and types of amblyopia were determined. Results: Amblyopia was found in 0.7 % (440) of 62,633 children examined in NEH during this period. All the amblyopic eyes of the subjects had refractive error. Fifty-six percent (248) of the patients were male and the mean age was 7.74 ± 2.97 years. Anisometropia was the most common cause of amblyopia (p < 0.001). One third (29 %) of the subjects had bilateral amblyopia due to high ametropia. Forty percent of eyes had severe amblyopia with visual acuity of 20/120 or worse. About twothirds (59.2 %) of the eyes had astigmatism. Conclusion: The prevalence of amblyopia in the Nepal Eye Hospital is 0.7%. Anisometropia is the most common cause of amblyopia. Astigmatism is the most common types of refractive error in amblyopic eyes. Nepal J Ophthalmol 2013; 5(9):38-44 DOI: http://dx.doi.org/10.3126/nepjoph.v5i1.7820

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