Epidemiological evaluation of cardiovascular disease and other non-cancer diseases following radiation exposure

Reactive oxygen species (ROS) are molecules involved in signal transduction pathways with both beneficial and detrimental effects on human cells. ROS are generated by many cellular processes including mitochondrial respiration, metabolism and enzymatic activities. In physiological conditions, ROS levels are well-balanced by antioxidative detoxification systems. In contrast, in pathological conditions such as cardiovascular, neurological and cancer diseases, ROS production exceeds the antioxidative detoxification capacity of cells, leading to cellular damages and death. In this review, we will first describe the biology and mechanisms of ROS mediated oxidative stress in cardiovascular disease. Second, we will review the role of oxidative stress mediated by oncological treatments in inducing cardiovascular disease. Lastly, we will discuss the strategies that potentially counteract the oxidative stress in order to fight the onset and progression of cardiovascular disease, including that induced by oncological treatments.

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The health benefits of UV radiation exposure through vitamin D production or non-vitamin D pathways. Blood pressure and cardiovascular disease

Photochemical & Photobiological Sciences ◽

10.1039/c6pp00336b ◽

2017 ◽

Vol 16 (3) ◽

pp. 374-380 ◽

Cited By ~ 20

Author(s):

Richard B. Weller

Keyword(s):

Blood Pressure ◽

Cardiovascular Disease ◽

Vitamin D ◽

Nitrogen Oxides ◽

Radiation Exposure ◽

Uv Radiation ◽

Health Benefits ◽

Systemic Circulation

UV photoreduces nitrogen oxides sequestered in the skin. The resulting NO moves to the systemic circulation where it vasodilates and lowers BP.

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Fatal and non-fatal cancer and medical radiation exposure in a population hospitalized for cardiovascular disease

European Heart Journal ◽

10.1093/eurheartj/eht307.p267 ◽

2013 ◽

Vol 34 (suppl 1) ◽

pp. P267-P267

Author(s):

C. Carpeggiani ◽

P. L. Landi ◽

C. M. Michelassi ◽

E. P. Picano

Keyword(s):

Cardiovascular Disease ◽

Radiation Exposure ◽

Medical Radiation ◽

Medical Radiation Exposure

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Breast artery calcification and osteoporosis in postmenopausal woman: a case report and opinion on the problem

CARDIOVASCULAR THERAPY AND PREVENTION ◽

10.15829/1728-8800-2020-2574 ◽

2020 ◽

Vol 19 (4) ◽

pp. 2574

Author(s):

E. V. Bochkareva ◽

E. K. Butina ◽

A. S. Savin ◽

O. M. Drapkina

Keyword(s):

Breast Cancer ◽

Cardiovascular Disease ◽

Case Report ◽

Postmenopausal Woman ◽

Vascular Calcification ◽

Screening Test ◽

Female Population ◽

Non Communicable Diseases ◽

Increased Risk ◽

Cancer Diseases

Mammography is one of the most common screening test in the female population. In addition to identifying breast cancer, vascular calcification is clearly visualized on the mammogram, which is associated with an increased risk of cardiovascular disease, atherosclerosis, and a number of other chronic non-communicable diseases. The article presents a case report of a postmenopausal woman with breast artery calcification and osteoporosis. Identification of women at risk of non-cancer diseases significantly expands the prospects of using mammography for screening.

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