scholarly journals Study of Thyroid Disorders in Type 2 Diabetic and Non-Diabetic Patients Attending a Tertiary Care Hospital

2020 ◽  
Vol 7 (46) ◽  
pp. 2669-2673
Author(s):  
Ravinder Pal Singh ◽  
Rajan Goyal ◽  
Nitin Kumar Gupta ◽  
Prerna Prerna ◽  
Abhinav Kumar

BACKGROUND Patients with DM are at increased risk of thyroid disease, especially those with poor glycaemic control. The following mechanisms are thought to be responsible. In patients with DM, the nocturnal TSH peak is blunted or abolished; the TSH response to TRH, from the hypothalamus, is impaired thus leading to hypothyroidism. We wanted to study the thyroid disorders in type 2 diabetic and non-diabetic patients attending a tertiary care hospital. METHODS This is an analytical observational study conducted among 100 type 2 diabetic and 100 non-diabetic patients attending medicine OPD in the Department of General Medicine of Narayan Medical College & Hospital, Jamuhar, Distt. Rohtas over a 6- month period from Oct 2019 to April 2020. RESULTS The mean age of group A and group B was found to be 51.79 ± 10.374 and 49.86 ± 9.538 respectively. In group A (diabetes mellitus patients), 71 (71 %) patients were euthyroid whereas in group B (healthy individuals) 84 (84 %) patients were euthyroid. In Group A (diabetes mellitus group) either subclinical or overt hypothyroidism was seen in 26 (26 %) patients and hyperthyroidism was seen in 3 (3 %) patients. In Group B (healthy individuals) either subclinical or overt hypothyroidism was seen in 14 (14 %) patients and hyperthyroidism was seen in 2 (2 %) patients. CONCLUSIONS The comparison of the patients of control and cases groups on the basis of whether they had a normal or abnormal thyroid function test showed that patients with diabetes mellitus type 2 (Group A) were more likely to be having abnormal thyroid function test as compared to healthy individuals (Group B) and this difference was found to be statistically significant (p = 0.027). KEYWORDS Type 2 DM, Hypothyroid, Hyperglycaemia, Hyperthyroid

Author(s):  
Abhishek Kamendu ◽  
Ahmad Nadeem Aslami

Background: Diabetes has become a major health challenge all over the world. Previous studies have found that diabetes and thyroid disorders mutually influence each other and both disorders tend to coexist. The aim of this study was to find out prevalence of hypothyroidism and its associated factors in type 2 diabetes mellitus patients.Methods: Consecutive 200 patients with type 2 diabetes mellitus attending outpatient department of medicine in a tertiary care centre in Sasaram, Bihar were evaluated clinically and biochemically. Subclinical hypothyroid and overt hypothyroidism was diagnosed as per standard definitions. The results obtained were statistically analysed by using chi square test and finding odds ratio.Results: Out of 200 patients, 75.5% were euthyroid while 24.5% were hypothyroid. Out of 49 hypothyroid patients, subclinical hypothyroid (SC-Hypo) was present in 41 patients and overt hypothyroid (C-Hypo) was present in only 8 patients. The prevalence of hypothyroidism was found more in males, age ≥60 years, patients with HbA1c value ≥7%, patients with diabetes duration less than 5 years and in hypertensive patients.Conclusions: Thyroid dysfunction screening should be done in all type 2 diabetic patients periodically and appropriate individualized treatments in addition to thyroid function test should be given to diabetes mellitus patients with subclinical hypothyroidism as well.


Author(s):  
Archana Kumari ◽  
Sony Sinha

Aim: to analyze the prevalence of glaucoma in type 2 diabetic patients. Materials and Methods: present observational study was undertaken in the Department of Ophthalmology, Patna Medical College and Hospital, Patna, Bihar, India for the period of one year. Total 100 patients of type 2 Diabetes Mellitus were included and detailed history was obtained. Results: Out of 100 diabetic patients 8 (8%) of them had glaucoma. Out of 8 diabetic patients with glaucoma 75.0% were male. The mean age reported was 58.16±4.81. Conclusion: This study highlights the prevalence and the demographic characteristics of glaucoma among diabetes mellitus patients in a tertiary care hospital of Bihar. Since, no such study has been done before in this region. Keywords: Type 2 diabetes, Glaucoma, Bihar


Author(s):  
Mohammad Masud Rana ◽  
Mohammad Shariful Islam ◽  
Jotsna Akter ◽  
Shanzida Khatun

Background: Diabetes Mellitus (DM) has been a global epidemic in the new millennium and the majority of all diabetic patients constitute Type 2 diabetes mellitus. Medication adherence to prescribed treatments is a key determinant to achieve therapeutic success reduces diabetic complications. Objectives: The aim of the study was to examine the level of medication adherence to Type 2 diabetic patients hospitalized at tertiary care hospital in Bangladesh. Methods: The study was descriptive cross-sectional design. A total of 112 Type 2 diabetic patients were conveniently recruited from tertiary care hospital in Bangladesh. Results: The mean age of the participants was 57.46 (SD=11.65) years. More than half of the patients (60.7%) were male and majority of them (94.6%) were married. The mean score of diabetic medication adherence was calculated as 26.46 (SD=1.58). Adherence to diabetic medications was significantly associated with age (p=.01), occupation (p=.003), duration of DM (p=.003), oral hypoglycemic agents (p=.02), HbA1c (p=< .01) and Fasting Blood Ssugar (p=< .01). Medication non-adherence significantly found in patients with presence of diabetic retinopathy (p=<.01), microabuminuria (p=.01), dyslipidemia (p=.006), hypertension (p=.01) and other chronic diseases (p=.01). Conclusion: The level of medication adherence among Type 2 diabetic patients was found to be suboptimal. Good adherence has beneficial effects on HbA1c and FBS. For improving adherence particular focus should pay to diabetic patients with different age groups and the presence of comorbidities. Keywords: Medication Adherence; Type 2 Diabetes Mellitus; Oral Hypoglycemic Agents; Comorbidities.


2020 ◽  
Vol 7 (6) ◽  
pp. 983
Author(s):  
Prakash Ranjan ◽  
Jayanta K. Das

Background: The prevalence of stress and anxiety in diabetes is considerably higher than normal population and found to have a negative impact on diabetes. The aim of this study was to examine the relationships among perceived diabetes-related stress and anxiety behaviors in adults living with type 2 diabetes (T2DM).Methods: In this descriptive and cross sectional study, systematic random sampling technique was used to select the sample of type 2 diabetic patients. Scheduled interview of 412 type 2 diabetic patient was conducted at outpatient department of a tertiary care hospital in New Delhi.Results: Out of 412 diabetic patients, 58.7 percent feel diabetes-related stress and anxiety behaviors when they think about living with diabetes. Age of patients, educational status, occupation and average monthly family income of diabetic patients are statistically associated with perceived diabetes-related stress and anxiety behaviors of type 2 diabetes mellitus patients. Lifestyle behaviour like diet pattern (vegetarian or nonvegetarian diet) and moderate intensity activities like walking are also statistically associated with perceived diabetes-related stress and anxiety behaviors of type 2 diabetes mellitus patients.Conclusions: This study found a high prevalence of diabetes-related stress and anxiety behavior in patients with Type 2 DM. Therefore, the care of individuals with type 2 Diabetes Mellitus (DM) should include the screening and possible management of stress and anxiety in order to achieve and sustain treatment goals.


Author(s):  
Archana Kumari ◽  
Sony Sinha

Aim: to analyze the prevalence of diabetic retinopathy in type 2 diabetic patients. Materials and Methods: present observational study was undertaken in the Department of Ophthalmology, Patna Medical College and Hospital, Patna, Bihar, India for the period of one year. Total 100 patients of type 2 Diabetes Mellitus were included and detailed history was obtained. Results: Out of 100 diabetic patients 21 (21%) of them had diabetic retinopathy. Out of 21 diabetic patients with diabetic retinopathy 61.9% were male. The mean age reported was 58.16±4.81. Conclusion: This study highlights the prevalence and the demographic characteristics of diabetic retinopathy among diabetes mellitus patients in a tertiary care hospital of Bihar. Since, no such study has been done before in this region. Keywords: Type 2 diabetes, Retinopathy, Bihar


2021 ◽  
Vol 8 (37) ◽  
pp. 3334-3338
Author(s):  
Satish Kumar

BACKGROUND Type 2 diabetes mellitus is common in the Indian population and awareness regarding the disease and its complications is low among the patients with diabetes. There is lack of studies regarding awareness of complications of diabetes among type 2 diabetic patients. The purpose of this study was to assess the awareness of diabetic complications among type 2 diabetic patients. METHODS This is an institutional based observational study. The sample comprised of 150 adult patients with type 2 diabetes mellitus who underwent treatment in the Department of Medicine, Medical College Kottayam and the patient’s age ranged from 18 - 77 years. RESULTS Majority of patients were in the age group 38 to 57 and the sample comprised of 56 % males and 44 % female patients. Out of 150 patients involved in the study, 120 patients (80 %) were aware of the complications of diabetes mellitus. Among the male patients, 70 (83.33 %) and among females, 50 (75.75 %) were aware of the complications in diabetes. In the study sample, 92 (61.33 %) were aware of the foot problems, 120 patients (80 %) were aware of renal complications, 91 patients were aware regarding eye problems of diabetes, 38 (25.33 %) regarding development of hypertension, 62 (41.33 %) regarding heart attack, 42 (28 %) patients were aware regarding development of stroke and 78 patients (52 %) had awareness regarding occurrence of recurrent infections. CONCLUSIONS Awareness regarding diabetes and its complications is fairly good among the diabetic patients in Kerala. Awareness regarding all complications of diabetes was higher among males than females. Providing awareness to type 2 diabetic patients by various educational programs may be of further help to prevent complications and to decrease the mortality and morbidity in type 2 diabetes patients. KEYWORDS Awareness, Diabetes


2020 ◽  
Vol 11 (1) ◽  
pp. 93-108
Author(s):  
Madhavi Mannam ◽  
Lavanya Nalluri ◽  
Dhanalakshmi Pinnika ◽  
Mounika Pothuraju ◽  
Ravindrababu Pingili ◽  
...  

Diabetic nephropathy is the leading cause of the end-stage renal disease (ESRD) worldwide, and it is estimated that ~ 20% of type 2 diabetic patients reach ESRD during their lifetime. The objective of the present study was to assess the drug utilization pattern, risk factors, and prevalence of diabetic nephropathy in patients with type 2 diabetes mellitus in a south Indian tertiary care hospital. A cross-sectional observational study was conducted on 613 subjects (254 with and 359 without diabetic nephropathy). Prevalence of diabetic nephropathy was measured, and risk factors for the development of diabetic nephropathy were determined by calculating odds ratios using graph-pad prism statistical software, and drug utilization pattern was assessed. Nephropathy was significantly higher in subjects who are married (98.8%, OR, 3.903; 95% CI, 1.125-13.54, P=0.0211),  poorly educated (61%, OR, 0.3670;95%CI, 0.2635-0.5112, P<0.0001), house wives (44.4%, OR, 0.5492; 95% CI, 0.3432 - 0.8789, P=0.0120), rural residents (51.2%, OR, 0.3943; 95% CI, 0.2820-0.5513, P<0.0001) and risk factors were hypertension (37.44%, OR, 4.131; 95% CI, 2.687-6.350, P<0.0001), other diseases (36.51%, OR, 4.963; 95% CI, 3.202 -7.692, P<0.0001), Endocrine diseases (9.53%, OR, 2.460; 95% CI, 1.433- 4.224, P=0.0009), history of CVD (7.90%, OR, 17.20; 95% CI, 7.049- 41.95, P<0.0001), HbA1c (36.1%, OR, 3.380; 95% CI, 2.157- 5.295, P<0.0001), low HDL (23%, OR, 0.5961; 95% CI, 0.3572 - 0.9947 , P=0.0470), high FBS levels (29.3%, OR, 6.111; 95%CI, 1.283 -29.10, P=0.0113), high triglyceride levels (39.8%, OR, 0.6077; 95%CI, 0.3878 -0.9523, P=0.0293), high serum creatinine (28.3%, OR, 154.3; 95% CI, 37.92- 627.7, P<0.0001), duration of T2DM(5-10years 39.8%, OR, 2.653;95% CI, 1.778 - 3.958, & > 10 years 37%, OR, 3.606 ; 95% CI, 2.362-5.504, P<0.0001), physical inactivity(64.9%, OR, 0.5188;95% CI, 0.3727-0.7220 , P<0.0001), soft drinks occasionally (31.9%, OR, 2.253; 95% CI, 1.531-3.315, P<0.0001), habit of taking tea /coffee twice without sugar(42.3%, OR, 1.845; 95% CI, 1.094 to 3.112, P=0.0208) were significant risk factors for development of nephropathy. Metformin (47.05%), a combination of Glimepiride and Metformin (30.71%), a combination of insulin isophane and insulin regular (29.41%), teneligliptin (10.45%), insulin regular (9.80%) were the anti-diabetic medications mostly given to the T2DM patients with nephropathy. The present study revealed that the risk factors for the development of diabetic nephropathy were multiple.


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