scholarly journals Electrical function of the abdominal muscles after combined plastic of extensive median hernias in the context of connective tissue dysplasia

2019 ◽  
Vol 12 (3) ◽  
pp. 152-157
Author(s):  
Radu Railianu
Keyword(s):  
Connective Tissue ◽  
Abdominal Wall ◽  
Anterior Abdominal Wall ◽  
Clinical Signs ◽  
Clinical Severity ◽  
Abdominal Muscles ◽  
Abdominal Hernias ◽  
Connective Tissue Dysplasia ◽  
Optimal Rehabilitation ◽  
Relaxing Effect

Relevance. Improving the electrical function of abdominal muscles in patients with extensive median hernias of the anterior abdominal wall can be facilitated by optimizing the choice of methods for combined hernioplasty, taking into account the clinical severity of connective tissue dysplasia among the hernia carriers. Objective. Study the electrical function of abdominal muscles after the methods of combined hernioplasty of extensive median hernias, taking into account the severity of connective tissue dysplasia among the hernia carriers. Results.  The average numbers of electromyogram frequencies of the abdominal muscles of patients with extensive median hernias from the group without clinical signs of connective tissue dysplasia were almost the same after all the applied methods of combined hernioplasty. The predominance of the rectus muscles electric function over the lateral abdominal muscles among the patients of this group was 33,5 %. Electrofunctional rehabilitation of the abdominal muscles of patients in the second group of examinations depended on the method of combined hernioplasty and changed in the event of an increase or decrease in the severity of connective tissue dysplasia.  The recovery of electroactivity of abdominal muscles in the postoperative period in patients from the second group was more significant with an increase in the number of abdominal muscles applied to aponeuroses and vagina of relaxing sections, which contributed to an increase in mobility and contractility of the musculoaponeurotic layers of the anterior abdominal wall. Conclusions. Thus, with an increase in the severity of connective tissue dysplasia in patients with extensive median abdominal hernias, the method of combined hernioplasty with the most pronounced relaxing effect in relation to the anterior abdominal wall promoted optimal rehabilitation of abdominal muscles.

scholarly journals Skin biopsy as a method for determining indications for preventive endoprosthetics of the anterior abdominal wall

2020 ◽  
pp. 46-53
Author(s):  
Viktor A. Lazarenko ◽  
Sergey V. Ivanov ◽  
Ilya S. Ivanov ◽  
Evgeny G. Ob’edkov ◽  
Nikolay N. Grigor'ev ◽  
...  
Keyword(s):  
Connective Tissue ◽  
Skin Biopsy ◽  
Abdominal Wall ◽  
Anterior Abdominal Wall ◽  
Polarized Light ◽  
Structural Features ◽  
Collagen Fibers ◽  
Type Iii Collagen ◽  
Type I ◽  
Connective Tissue Dysplasia

The aim is to examine the effectiveness of preoperative skin biopsy method to determine indications for preventive endoprosthesis implantation of the anterior abdominal wall based on structural features of connective tissue. Materials and methods. The study included 17 patients who had been planned to undergo a scheduled surgery such as video laparoscopic cholecystectomy. The histological material was collected with DERMO PUNCH biopsy needles in an outpatient clinic. Using polarized light microscopy we inspected histological slices coloured with Sirius red. After that we analyzed histological sections including the ratio of collagen fibers, the density of connective tissue and the number of interfibrous spaces. Results. All the studied features of connective tissue dysplasia had been registered among 18% of patients; significant differences (p ≤0.05) had been identified among other 24% of patients. In patients with identified signs of connective tissue dysplasia, an increase in type III collagen fibers and a decrease in type I fibers were revealed, which directly resulted in a decrease in their ratio. In addition, this category of patients noted a decrease in the density of connective tissue and a significant number of interfibrous spaces. Conclusion. Skin biopsy is a safe and informative method to reveal patients with predisposition to the formation of hernias of the anterior abdominal wall based on structural features of connective tissue and to determine indications for preventive endoprosthetic implantation. This method will reduce the frequency of postoperative ventral hernias, so the effectiveness of the treatment will definitely increase.

scholarly journals EFFECT OF CONNECTIVE INSUFFICIENCY AND SIZES OF MEDIAN HERNIAS ON BEFORE AND POSTOPERATIVE FUNCTION OF THE ABDOMINAL MUSCLE

2019 ◽  
Vol 23 (1) ◽  
pp. 40-53
Author(s):  
R. I. Railianu ◽  
G. I. Podoliniy ◽  
A. V. Marshaluk
Keyword(s):  
Connective Tissue ◽  
Abdominal Wall ◽  
Anterior Abdominal Wall ◽  
Abdominal Cavity ◽  
Abdominal Muscle ◽  
Original Method ◽  
Abdominal Muscles ◽  
Postoperative Function ◽  
Before And After ◽  
Clinically Significant

The article analyzes the results of electromyography of the abdominal muscles in 189 patients with median postoperative hernia of the anterior abdominal wall of different sizes before and after the combined methods of hernioplasty, including considering the level of connective tissue failure. In the preoperative period, electromyography was performed in 69 (36,6%), after combined hernioplasty, 120 (63,4%) patients. The patients were divided into a group of 161 (85,1%) patients with clinically significant or histologically confirmed connective tissue insufficiency and into a group of 28 (14,9%) patients without it. The distribution of patients in the examination groups was carried out using an original method of assessing the degree of deviation of collagen fibers from the projection of the Langer lines in microscopic specimens of the skin areas excised during the operation and based on the results of a retrospective analysis of case histories with determination of the intraoperative adhesions of the adhesions in the abdominal cavity or hernial sac. In the formed groups, we studied the amplitude, frequency, front and area of electromyograms obtained from the direct and lateral muscles of the anterior abdominal wall. It was found that in patients with median postoperative hernias, mesenchymal dysplasia was the main reason for the decrease in functional activity and the imbalance of forces between the direct and lateral abdominal muscles. Optimal restoration of electroactivity of the abdominal muscles after combined hernioplasty occurred among patients without clinically significant connective tissue insufficiency. When reaching a giant postoperative hernia of gigantic size in patients with a clinically significant level of connective tissue dysplasia, the functioning of the abdominal muscles decreased by 26%, and in patients without it only by 15%. The pathology of collagen in skin grafts excised during surgery was detected in 91,5% of patients with mid-incisional hernias.

scholarly journals CARDIAL MANIFESTATIONS OF NON-DIFFERENTIATED CONNECTIVE TISSUE DYSPLASIA AND THEIR INFLUENCE ON PREGNANCY

2021 ◽  
pp. 14-22
Author(s):  
V. Yu. DOBRIANSKA ◽  
S. M. HERYAK ◽  
L. M. MALANCHUK ◽  
M. I. SHVED ◽  
I. V. KORDA
Keyword(s):  
Mitral Valve ◽  
Connective Tissue ◽  
Ventricular Arrhythmia ◽  
Pregnant Women ◽  
Mitral Valve Prolapse ◽  
Clinical Signs ◽  
Clinical Manifestations ◽  
Adequate Treatment ◽  
Pregnancy And Childbirth ◽  
Connective Tissue Dysplasia

Among the visceral manifestations of NDST in pregnant women most often diagnosed mitral valve prolapse (20-25%) that accompanied by more cardiovascular and obstetric complications during pregnancy. It demonstrates the high clinical significance of the problem of connective tissue dysplasia with mitral valve prolaps for pregnancy and requires adequate treatment programs for prevention of complications and management of pregnant women with connective tissue dysplasia. Aim. Determination of the frequency of pregnancy pathology in women with clinical signs of NDST and MVP complicated by extrasystolic arrhythmia. Materials and methods. 138 pregnant women with MVP and concomitant signs of NDST and 54 healthy pregnant women were selected for analysis. Clinical manifestations of NDST, different variants of arrhythmias and the total number of complications of pregnancy and childbirth were evaluated. Results. In pregnant women with clinical signs of NDST and MVP complicated by extrasystolic arrhythmia, cases of frequent sinus extrasystole were significantly more often compared to frequent ventricular arrhythmia (47.8% vs. 18.1%, p<0.001) and cases of combination of frequent sinus extrasystole and ventricular arrhythmia (13.3 % vs. 1.5%, p <0.05). They significantly more often identified both symptoms of arrhythmological nature and symptoms that indicated a violation of autonomic status. The presence of NDST syndrome is more often accompanied by the development of complications of pregnancy and childbirth. These pregnant women have genetic and phenotypic risk factors for the development of pathological pregnancy and childbirth, birth trauma, disability of mother and newborn, which justifies such patients in a separate risk group for individualized programs of the prevention and treatment of visceral (cardiac) manifestations of NDST and possible complications of pregnancy and childbirth. Conclusions. 3.1% of pregnant women are diagnosed with phenotypic signs (stigma) of undifferentiated connective tissue dysplasia, and the most common visceral cardiac manifestation is mitral valve prolapse. The presence of mitral valve prolapse and extrasystolic arrhythmia in pregnant women with NDST is accompanied by significantly more frequent development of pregnancy and childbirth complications in these patients.

scholarly journals CLINICAL AND GENETIC FEATURES OF CONNECTIVE TISSUE DYSPLASIA SYNDROME IN CYSTIC FIBROSIS IN CHILDREN

2019 ◽  
Vol 21 (4) ◽  
pp. 203-207 ◽  
Author(s):  
Anastasia V. Goryainova ◽  
P. V. Shumilov ◽  
S. Yu. Semykin ◽  
G. Yu. Zobkova ◽  
A. E. Donnikov
Keyword(s):  
Cystic Fibrosis ◽  
Connective Tissue ◽  
Matrix Metalloproteinase ◽  
Clinical Signs ◽  
Respiratory Disorders ◽  
Matrix Metalloproteinase 3 ◽  
Genetic Features ◽  
Connective Tissue Dysplasia ◽  
Modifying Effect ◽  
Severe Pathology

The aim of the study was to determine the clinical and genetic features of the syndrome of undifferentiated connective tissue dysplasia (CTD) in cystic fibrosis (CF) children and the possible modifying effect of polymorphisms of connective tissue genes on the development of severe pathology of the bronchopulmonary system in CF cases. 188 patients with the moderate to severe course of СF, aged from 3 to 17 years were examined. In СF patients significant associations have been established between polymorphisms of matrix metalloproteinase 3, the phenotypic signs of CTD and severe clinical signs of respiratory disorders.

scholarly journals Influence of silver-ion-containing pharmacotherapeutic system for repair of anterior abdominal wall on connective tissue formation in experiment

2019 ◽  
Vol 5 (3) ◽  
pp. 57-66
Author(s):  
Ekaterina S. Mishina ◽  
Maria Zatolokina ◽  
Anastasia V. Gureeva ◽  
Vladimir V. Gureev ◽  
Karina A. Elagina ◽  
...  
Keyword(s):  
Connective Tissue ◽  
Abdominal Wall ◽  
Anterior Abdominal Wall ◽  
Rapid Change ◽  
Antibacterial Properties ◽  
Silver Ions ◽  
Modern Medicine ◽  
Connective Tissue Capsule

Introduction: In modern medicine new pharmacotherapeutic systems significantly reducing the risk of complications are being actively searched for. The study undertaken was aimed at studying one of such systems consisting of a prosthesis coated with silver ions. Materials and methods: The material for the study was standard endoprostheses produced by Lintex LLC (St.-Petersburg) for plastic repair of the anterior abdominal wall: Esfil and Uniflex, as well as Plasmofilter produced by Plasmofilter JSC (St.-Petersburg) and a pharmacotherapeutic system containing silver ions (FCS) applied to the experimental samples of endoprostheses – Esfil Ag and Unifleks Ag (patent RU 2473369C1), which were implanted into male Wistar rats. The results were evaluated using morphological, morphometric, immunohistochemical, ionometric, microbiological and statistical methods. Results and discussion: As a result, it was found that the use of the FCS leads to a more rapid change in inflammation phases. The formation of a mature connective tissue capsule with a thickness of 4.5±0.01 mm was observed by Day 30. The study of the cellular component of the periprosthetic tissue revealed the prevalence of resident cells. The proliferative activity of fibroblastic cells when using FCS over 14 days was statistically significantly (p≤0.05) 3.5-time higher. Microbiological studies confirmed the antibacterial properties of FCS in vivo and in vitro. Conclusion: The use of FCS contributes to the acceleration of reparative processes, earlier resolution of inflammation and stimulation of collagenesis both under sterile conditions and under microbial conditions.

scholarly journals ANALYSIS OF NONSURGICAL POSTOPERATIVE VENTRAL HERNIA PREDICTORS

2017 ◽  
Vol 34 (6) ◽  
pp. 5-11
Author(s):  
S N Lebedev ◽  
A V Fedoseev ◽  
A S Inyutin ◽  
S Yu Muraviyev
Keyword(s):  
Surgical Treatment ◽  
Abdominal Wall ◽  
Anterior Abdominal Wall ◽  
Prospective Analysis ◽  
Case Histories ◽  
Endoprosthetic Replacement ◽  
Midline Laparotomy ◽  
Urgent Surgery ◽  
Connective Tissue Dysplasia ◽  
Blood Erythrocyte

Aim. The aim of this study was to detect the predictors of the postoperative herniation in midline laparotomy as the most frequent type of approach in urgent surgery. The study included retro-and-prospective analysis of 398 case histories. Analysis was performed according to 45 signs. Materials and methods. The following parameters were taken into account: Kettle index, anterior abdominal wall status, presence of the signs of undifferentiated connective tissue dysplasia, hard physical labour, use of bandage in the postoperative period as well as blood erythrocyte and hemoglobin indices, bilirubin and creatinine levels. Separately, the following parameters were assessed: presence of aponeurosis defects (physically and by US data) and presence of hernia outpouching. Results. According to the obtained data, the indications to preventive endoprosthetic replacement of the anterior abdominal wall were formed. Conclusions. Combination of some factors, not connected with surgical treatment, raises the risk for herniation, being the indication to preventive endoprosthesis replacement of the abdominal wall.

Two cases of bone formation in the postoperative scar of the abdominal wall

1930 ◽  
Vol 26 (2) ◽  
pp. 187-188
Author(s):  
V. E. Rodionov
Keyword(s):  
Connective Tissue ◽  
Bone Formation ◽  
Abdominal Wall ◽  
Abdominal Muscles ◽  
Apparent Reason ◽  
Postoperative Scar ◽  
Mixed Tumors

Histogenetically similar cells can sometimes undergo metaplasia under the influence of little-known reasons. In some cases, the transformation of one type of tissue into another occurs for no apparent reason, such as in various kinds of mixed tumors; in other cases, we observe the phenomenon of metaplasia in chronic tissue irritation (Podvysotsky). Our cases of ossification of the postoperative scars of the abdominal wall and can be interpreted in terms of prolonged irritation of the connective tissue of the aponeurosis of the abdominal muscles with silk sutures, for which, to a certain extent, the shape of the bone formations speaks.

scholarly journals A TISSUE REACTION TO COMBINED HERNIA PROSTHESIS AT DIFFERENT POSTOPERATIVE P

2020 ◽  
Vol 10 (4) ◽  
pp. 94-95
Author(s):  
Valery Nikolskiy ◽  
Ekaterina Titova ◽  
Yaroslav Feoktistov ◽  
Vladislav Kiselev
Keyword(s):  
Connective Tissue ◽  
Abdominal Wall ◽  
Anterior Abdominal Wall ◽  
Abdominal Cavity ◽  
Tissue Reaction ◽  
Synthetic Material ◽  
Internal Organs ◽  
Morphological Response ◽  
Polyester Mesh ◽  
Morphometric Assessment

Our experimental study shows a morphological response of the anterior abdominal wall to implantation of a combined (bovine pericardium graft and polyester mesh) hernia prosthesis. For this purpose, fifteen chinchillas were operated on. A combined prosthesis was implanted intra-abdominally, where the pericardium graft adjoined the internal organs with the smooth side, while the synthetic material was facing the peritoneum. Morphological and morphometric assessment of the tissue in the area of implantation of the prosthesis was carried out. Morphology of tissues samples was evaluated in 2 weeks, in 1 month and in 2 months after surgery. Our study revealed that the combined prosthesis implanted in the anterior abdominal wall causes an acute inflammatory response, which progresses within a month after the surgery. However, the signs of inflammation reduced at the end of the second month of the experiment. A new connective tissue grew actively into the implant from the side of the polyester mesh. The pericardium graft adjacent to the abdominal cavity with the smooth side did not cause formation of connective tissue. Thus, the combined hernia prosthesis has protected the abdominal cavity from adhesions in the postoperative period.

Sign in / Sign up

Export Citation Format

Share Document