scholarly journals Diagnosis and Treatment of Acute Pancreatitis: Bibliographic Review

2021 ◽  
Author(s):  
César Lenin Pilamunga Lema ◽  
Johanna Elizabeth Villafuerte Morales
Keyword(s):  
Acute Pancreatitis ◽  
Diagnosis And Treatment ◽  
C Reactive Protein ◽  
Endoscopic Retrograde ◽  
N Nutrition ◽  
Reactive Protein ◽  
Palabras Clave ◽  
Clinical Radiology ◽  
Endoscopic Cholangiopancreatography ◽  
Upper Abdominal

  Introduction: Acute pancreatitis (AP) is a sudden, reversible inflammatory process of the pancreas, caused by self-digestion. In Ecuador in 2016, 4715 cases were presented, with a mortality of 2.99%. The etiology includes gallstones, alcoholism, hypertriglyceridemia. It presents with upper abdominal pain, nausea and vomiting, it is hospital management. Methodology: It is a descriptive review of the literature on the diagnosis and treatment of BP, based on 31 articles in English and Spanish. Discussion  and Results: AP is diagnosed by the clinic and by the serum measurement of lipase and pancreatic amylase. You can also perform other studies such as C-reactive protein, alanine aminotransferase, aspartate aminotransferase, ultrasonography, computed tomography, magnetic resonance imaging, among others. The management of the intake as the main points of perfusion, analgesia, nutrition, clinical, radiology, retrograde endoscopic cholangiopancreatography, antibiotic and surgery. Conclusion: Although the diagnosis is generally clinical and laboratory, for atypical cases, imaging studies are very useful to confirm or exclude the diagnosis. The treatment of PA is summarized in the PANCREAS nemotechnics. (P perfusion, A analgesia, N nutrition, C clinical, R radiology, E endoscopic retrograde cholangiopancreatography, A antibiotic, S surgery). Keywords: pancreatitis, inflammation, diagnosis, treatment. RESUMEN Introducción: La pancreatitis aguda (PA) es un proceso inflamatorio repentino, reversible del páncreas, causado por autodigestión. En Ecuador en el 2016 se presentaron 4 715 casos, con una mortalidad del 2,99%. En la etiología constan: Cálculos biliares, alcoholismo, hipertrigliceridemia. Se presenta con dolor abdominal superior, náuseas y vómito, es de manejo hospitalario. Metodología: Es una revisión bibliográfica descriptiva, sobre el diagnóstico y tratamiento de la PA, en base a 31 artículos en inglés y español. Discusión y Resultados: La PA se diagnostica mediante la clínica y por la medición sérica de lipasa y amilasa pancreática; también se pueden realizar otros estudios como proteína C reactiva, alanina aminotranferasa, aspartato aminotransferasa, ultrasonografía, tomografía computarizada, imagen por resonancia magnética, entre otros. El tratamiento apunta a brindar una adecuada perfusión de tejidos, buena analgesia y principalmente evitar complicaciones. El manejo toma como como principales puntos perfusión, analgesia, nutrición, clínica, radiología, colangiopancreatografia retrograda endoscópica, antibiótico y cirugía. Conclusiones: A pesar de que el diagnóstico es generalmente clínico y de laboratorio, para casos atípicos son de gran utilidad los estudios de imagen para confirmar o excluir el diagnóstico. El tratamiento de PA se resume en la nemotecnia PANCREAS. (P perfusión, A analgesia, N nutrición, C clínica, R radiología, E colangiopancreatografía retrógrada endoscópica, A antibiótico, S cirugía). Palabras clave: pancreatitis, inflamación, diagnóstico, tratamiento.

The Prognostic Value of Different Levels of Cortisol and High-sensitivity C-reactive Protein in Early Acute Pancreatitis

2021 ◽  
Author(s):  
Hanan Sharaf El-Deen Mohammed ◽  
Haidi Karam-Allah Ramadan ◽  
Reham I El-Mahdy ◽  
Entsar H Ahmed ◽  
Amal Hosni ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Prognostic Value ◽  
High Sensitivity ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Different Levels

Misinterpretation of C reactive protein level and white blood cell count are behind the overuse of antibiotics in acute pancreatitis

Pancreatology ◽  
2017 ◽  
Vol 17 (3) ◽  
pp. S109
Author(s):  
Eszter Tóth ◽  
Tamás Lantos ◽  
Dóra Illés ◽  
Szilárd Gódi ◽  
Ákos Szűcs ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Blood Cell ◽  
Cell Count ◽  
White Blood Cell Count ◽  
White Blood Cell ◽  
Protein Level ◽  
C Reactive Protein ◽  
Blood Cell Count ◽  
Reactive Protein

scholarly journals Intrapancreatic fat deposition and visceral fat volume are associated with the presence of diabetes after acute pancreatitis

2019 ◽  
Vol 316 (6) ◽  
pp. G806-G815 ◽  
Author(s):  
Ruma G. Singh ◽  
Aya Cervantes ◽  
Jin Uk Kim ◽  
Ngoc Nhu Nguyen ◽  
Steve V. DeSouza ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Visceral Fat ◽  
Volume Ratio ◽  
Ectopic Fat ◽  
C Reactive Protein ◽  
Fat Percentage ◽  
Related Factors ◽  
Protein Levels ◽  
Reactive Protein ◽  
Fat Volume

Ectopic fat and abdominal adiposity phenotypes have never been studied holistically in individuals after acute pancreatitis (AP). The aim of the study was to investigate phenotypical differences in ectopic fat and abdominal fat between individuals after AP (with and without diabetes) and to determine the role of pancreatitis-related factors. Eighty-four individuals were studied cross-sectionally after a median of 21.5 mo since last episode of AP and were categorized into “diabetes” and “no diabetes” groups. Twenty-eight healthy volunteers were also recruited. With the use of magnetic resonance imaging, intrapancreatic fat percentage, liver fat percentage, visceral fat volume (VFV), subcutaneous fat volume, and visceral-to-subcutaneous (V/S) fat volume ratio were quantified. Analysis of variance was used to investigate the differences in these phenotypes between the groups. All analyses were adjusted for age and sex. Linear regression analysis was used to investigate the association between pancreatitis-related factors and the studied phenotypes. Intrapancreatic fat percentage was significantly higher in the diabetes group (10.2 ± 1.2%) compared with the no diabetes (9.2 ± 1.7%) and healthy volunteers (7.9 ± 1.9%) groups ( P < 0.001). VFV was significantly higher in the diabetes (2,715.3 ±1,077.6 cm3) compared with no diabetes (1,983.2 ± 1,092.4 cm3) and healthy volunteer (1,126.2 ± 740.4 cm3) groups ( P < 0.001). V/S fat volume ratio was significantly higher in the diabetes (0.97 ± 0.27) compared with no diabetes (0.68 ± 0.42) and healthy volunteer (0.52 ± 0.34) groups ( P = 0.001). Biliary AP was associated with significantly higher intrapancreatic fat percentage (β = 0.67; 95% CI, 0.01, 1.33; P = 0.047). C-reactive protein levels during hospitalization for AP were associated with significantly higher VFV (β = 3.32; 95% CI, 1.68, 4.96; P < 0.001). In conclusion, individuals with diabetes after AP have higher intrapancreatic fat percentage, VFV, and V/S fat volume ratio. Levels of C-reactive protein during AP are significantly associated with VFV, whereas biliary AP is significantly associated with intrapancreatic fat percentage. NEW & NOTEWORTHY Individuals with diabetes after acute pancreatitis have significantly higher intrapancreatic fat percentage and visceral fat volume compared with individuals without diabetes after acute pancreatitis and healthy controls. C-reactive protein levels during hospitalization for acute pancreatitis and biliary etiology of acute pancreatitis are associated with significantly larger visceral fat and pancreatic fat depots, respectively.

Meta-analysis of the role of C-reactive protein in predicting severity of acute pancreatitis

Pancreatology ◽  
2013 ◽  
Vol 13 (2) ◽  
pp. e39-e40
Author(s):  
T. Jin ◽  
K. Altaf ◽  
J.J. Xiong ◽  
M.A. Javed ◽  
W. Huang ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Meta Analysis ◽  
C Reactive Protein ◽  
Reactive Protein

Monocyte and neutrophil direct counts correlate with C-reactive protein plasma concentration in patients with acute pancreatitis

Open Medicine ◽  
2007 ◽  
Vol 2 (1) ◽  
pp. 26-36
Author(s):  
Jerzy Naskalski ◽  
Barbara Maziarz ◽  
Beata Kusnierz-Cabala ◽  
Paulina Dumnicka ◽  
Józefa Panek
Keyword(s):  
Acute Pancreatitis ◽  
Plasma Concentration ◽  
Blood Cells ◽  
Regression Equation ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Wbc Count ◽  
The Relationship ◽  
Concentration Levels ◽  
Direct Counts

AbstractAcute pancreatitis (AP) is associated with the intensive inflammatory response in white blood cells (WBC) and C-reactive protein (CRP). This paper presents the relationship between the CRP plasma concentration and the direct counts of peripheral WBC in AP during the initial five days. The study consisted of 56 patients with AP, 36 patients with mild form of AP and 20 patients with severe form of AP. ABX VegaRetic hematological analyzer was used to perform the count of blood cells, and the immunonephelometric method was performed to measure the CRP concentration levels. AP patients presented with WBC count values in the range of 3.2 − 22.4 × 103/µl and CRP concentration levels in the range 3.3 − 599.8 mg/l. The WBC count correlates with CRP levels during the entire observation period. The relationship of CRP and WBC is expressed in the following regression equation: WBC (103/µl) = 3.66 + 1.40 × logeCRP (mg/l). The highest median neutrophil count (8.15 × 103/µl) was observed on the first day. The count decreased to 5.27 × 103/µl on the fifth day. The most substantial finding in this study involved the values found for the monocytes and CRP (r= 0.53; p<0.001). Day two and day three were the highest (r=0.59, p<0.001). On day two, the regression equation for this relationship is: Monocytes (103/µl) = −0.34 + 0.21 × logeCRP(mg/l). The correlation between direct monocyte count and plasma CRP concentration in AP reflect a CRP-dependent stimulation of IL-6 release from activated blood monocytes.

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