Nonlinear Optical Investigation of Biochemical Analytes in Blood Serum via Z-Scan Technique

2021 ◽  
Author(s):  
Samane Raji ◽  
Mohammad Ali Haddad ◽  
Seyed Mohammad Moshtaghioun ◽  
Zahra Dehghan
Keyword(s):  
Refractive Index ◽  
Blood Serum ◽  
Nonlinear Refractive Index ◽  
Nonlinear Optical ◽  
Diagnostic Procedures ◽  
Biological Tissues ◽  
Optical Characteristics ◽  
Closed Aperture ◽  
Optical Investigation ◽  
Medical Diagnoses

Background and Aims: Biomolecules' optical and nonlinear optical properties are widely used for different medical diagnoses and applications in biophotonic devices. These properties are essential in studying biological processes in living tissues. Aside from biomolecules' linear optical characteristics, their nonlinear optical characteristics have lately been considered. Materials and Methods: In this paper, the nonlinear optical responses of three biochemical analytes in blood serum, including glucose, triglycerides, and cholesterol are examined using the laser-based Z-Scan technique. Hence, different laboratory samples of blood serum with various concentrations of biochemical analytes are taken from patients for this purpose. Results: The normalized transmission curves were taken and analyzed in a closed aperture configuration of the Z-Scan technique and led to evaluating the nonlinear refractive index (n2) as an indicator of nonlinear responses of samples. The results show significant nonlinear optical behaviors of the samples under a strong electrical field of the laser, which leads to the measurement of the nonlinear refractive index (n2) of the samples with an error of less than ̴ 0.5 × 10-8 cm2/w. It is found that the values of nonlinear refractive index (n2) vary proportionally as a function of their concentration in blood serum. Conclusion: The findings of this study imply that the above sample's nonlinear optical response and, probable, those of other biological tissues might be used in medical diagnoses. In addition, the Z-Scan technique might be considered as a complementary method with other conventional diagnostic procedures due to its simplicity and quick experimental approach.

scholarly journals Fused ring effect on optical nonlinearity and structure property relationship of anthracenyl chalcone based push-pull chromophores

PLoS ONE ◽  
2021 ◽  
Vol 16 (9) ◽  
pp. e0257808
Author(s):  
Dian Alwani Zainuri ◽  
Mundzir Abdullah ◽  
Muhamad Fikri Zaini ◽  
Hazri Bakhtiar ◽  
Suhana Arshad ◽  
...  
Keyword(s):  
Refractive Index ◽  
Optical Properties ◽  
Electrostatic Potential ◽  
Nonlinear Refractive Index ◽  
Optical Switching ◽  
Nonlinear Optical ◽  
Continuous Wave ◽  
Excited State Absorption ◽  
Nonlinear Optical Properties ◽  
Closed Aperture

The Ultraviolet-visible (UV-Vis) spectra indicate that anthracenyl chalcones (ACs) have high maximum wavelengths and good transparency windows for optical applications and are suitable for optoelectronic applications owing to their HOMO–LUMO energy gaps (2.93 and 2.76 eV). Different donor substituents on the AC affect their dipole moments and nonlinear optical (NLO) responses. The positive, negative, and neutral electrostatic potential regions of the molecules were identified using molecular electrostatic potential (MEP). The stability of the molecule on account of hyperconjugative interactions and accompanying charge delocalization was analyzed using natural bond orbital (NBO) analysis. Open and closed aperture Z-scans were performed using a continuous-wave frequency-doubled diode-pumped solid-state (DPSS) laser to measure the nonlinear absorption and nonlinear refractive index coefficients, respectively. The valley-to-peak profile of AC indicated a negative nonlinear refractive index coefficient. The obtained single crystals possess reverse saturation absorption due to excited-state absorption. The structural and nonlinear optical properties of the molecules have been discussed, along with the role of anthracene substitution for enhancing the nonlinear optical properties. The calculated third-order susceptibility value was 1.10 x10-4 esu at an intensity of 4.1 kW/cm2, higher than the reported values for related chalcone derivatives. The NLO response for both ACs offers excellent potential in optical switching and limiting applications.

NONLINEAR OPTICAL PROPERTIES OF ACID ORANGE 10 DYE BY Z-SCAN TECHNIQUE USINGAr+LASER

2007 ◽  
Vol 16 (03) ◽  
pp. 359-366 ◽  
Author(s):  
AHMAD Y. NOORALDEEN ◽  
A. N. DHINAA ◽  
P. K. PALANISAMY
Keyword(s):  
Aqueous Solution ◽  
Refractive Index ◽  
Nonlinear Refractive Index ◽  
Nonlinear Optical ◽  
Closed Aperture ◽  
Limiting Behavior ◽  
Nlo Properties ◽  
Acid Orange ◽  
Potential Applications ◽  
Acid Orange 10

Nonlinear optical (NLO) properties of the aqueous solution of Acid Orange 10 dye have been studied using the closed aperture and open aperture Z-scan technique at different concentrations and various powers of Ar+laser at 488 nm wavelength. The nonlinear refractive index (n2) shows negative nonlinearity for all concentrations studied, and it is measured to be -13.5 × 10-9cm2/ W at 0.05 mM concentration. Moreover, the nonlinear refractive index is found to vary with intensity and concentration. The nonlinear absorption coefficient (β) is measured to be -3.8 × 10-4cm/W . Optical limiting behavior has been demonstrated for this dye. These results show that Acid Orange 10 dye has potential applications in nonlinear optics.

Investigating the Nonlinear Optical Response of Pepper Oil under Low Power Irradiation with Continuous Wave Visible Laser Beam

2020 ◽  
pp. 131-138
Keyword(s):  
Refractive Index ◽  
Nonlinear Refractive Index ◽  
Nonlinear Optical ◽  
Continuous Wave ◽  
Diffraction Integral ◽  
Visible Laser ◽  
Limiting Property ◽  
Kirchhoff Diffraction Integral ◽  
Theoretical Results ◽  
Good Agreement

The nonlinear optical properties of pepper oil are studied by diffraction ring patterns and Z-scan techniques with continuous wave beam from solid state laser at 473 nm wavelength. The nonlinear refractive index of the sample is calculated by both techniques. The sample show high nonlinear refractive index. Based on Fresnel-Kirchhoff diffraction integral, the far-field intensity distributions of ring patterns have been calculated. It is found that the experimental results are in good agreement with the theoretical results. Also the optical limiting property of pepper oil is reported. The results obtained in this study prove that the pepper oil has applications in nonlinear optical devices.

scholarly journals Studying the Nonlinear Optical Properties of Fluoride Laser Host Materials in the Ultraviolet Wavelength Region

2021 ◽  
Vol 12 (1) ◽  
pp. 372
Author(s):  
Duong Van Pham ◽  
Diep Van Nguyen ◽  
Tu Xuan Nguyen ◽  
Kieu Anh Thi Doan ◽  
Quan Minh Le ◽  
...  
Keyword(s):  
Refractive Index ◽  
Optical Properties ◽  
Ultrashort Pulse ◽  
Nonlinear Refractive Index ◽  
Nonlinear Optical ◽  
Wavelength Region ◽  
Aluminum Fluoride ◽  
Self Focusing ◽  
Host Materials ◽  
Ultraviolet Wavelength

Fluoride host materials doped with trivalent cerium ions have previously been demonstrated as successful laser materials in the ultraviolet wavelength region. However, the nonlinear optical properties of the fluoride hosts in this wavelength region have not been investigated yet, although nonlinearity could result in undesirable effects such as self-focusing and pulse distortion when these fluoride materials are used as gain media in high-power, ultrashort pulse laser oscillator and amplifier systems. In this work, the nonlinear refractive index of lithium calcium aluminum fluoride (LiCaAlF6), lithium strontium aluminum fluoride (LiSrAlF6), lanthanum fluoride (LaF3), and yttrium lithium fluoride (YLiF4) fluoride host materials are determined using the Kramers–Krönig relation model in the ultraviolet wavelength region. Self-focusing conditions, particularly at the peak laser emission wavelength of these materials, are further analyzed. Results show that LiCaAlF6 has the smallest nonlinear refractive index and self-focusing, making it an ideal host material under the conditions of ultrashort pulse and ultrahigh-power laser generation.

Third-order optical nonlinearity of DSR13/THF solutions under CW He–Ne laser irradiation using Z-scan method

2021 ◽  
pp. 1-7
Author(s):  
Bassam Abbas ◽  
Mohammad Alshikh Khalil
Keyword(s):  
Refractive Index ◽  
Optical Properties ◽  
Nonlinear Absorption ◽  
Nonlinear Refractive Index ◽  
Nonlinear Optical ◽  
Nonlinear Optical Properties ◽  
Photon Absorption ◽  
Third Order ◽  
The Third ◽  
Order Susceptibility

The Z-scan technique was employed to explore the third-order nonlinear optical properties of disperse red 13 organic chromophore solutions in tetrahydrofuran. A continuous-wave He–Ne laser (632.8 nm) was used as a source of irradiation. The nonlinear absorption and nonlinear refractive index coefficients of this dye were investigated. The results showed that this dye has a good nonlinear response with its real and imaginary quantities of third-order susceptibility. The solutions showed negative nonlinear refraction. The best obtained value of the third-order susceptibility was 6.37 × 10–3 esu at a dye concentration of 3.15 × 10–4 mol/L. Moreover, the nonlinear optical properties were enhanced with higher dye concentrations, and an elevated trend in nonlinear absorption and nonlinear refractive index coefficients was observed. Also, it was found that the reverse saturable absorption was the main mechanism responsible for the two-photon absorption effect in DSR13/THF samples.

scholarly journals The effects of laser intensities on nonlinear properties for Ag nanoparticles colloid

2019 ◽  
Vol 15 (34) ◽  
pp. 36-40
Author(s):  
Mazin M. Elias
Keyword(s):  
Refractive Index ◽  
Nonlinear Refractive Index ◽  
Nonlinear Optical ◽  
Ccd Camera ◽  
Optical Response ◽  
Blue Laser ◽  
Nonlinear Optical Response ◽  
Third Order ◽  
Nonlinear Properties ◽  
Nano Fluid

A huge potential from researchers was presented for enhancing the nonlinear optical response for materials that interacts by light. In this work, we study the nonlinear optical response for chemically prepared nano- fluid of silver nanoparticles in de-ionized water with TSC (Tri-sodium citrate) protecting agent. By the means of self-defocusing technique and under CW 473 nm blue laser, the reflected diffraction pattern were observed and recorded by CCD camera. The results demonstrate that, the Ag nano-fluid shows a good third order nonlinear response and the magnitude of the nonlinear refractive index was in the order of 10−7 cm2/W. We determine the maximum change of the nonlinear refractive index and the related phase shift for the material at six input laser intensities.

scholarly journals NONLINEAR OPTICAL PROPERTIES AND OPTICAL POWER LIMITING OF THE PREPARED POLYMER BLEND POLY (3HT- Co - Th) - PM FILMS

2021 ◽  
Vol 5 (1) ◽  
pp. 1-10
Author(s):  
Imad Al-Deen Hussein Ali Al-Saidi ◽  
Hussein Falih Hussein ◽  
Numan Sleem Hashim
Keyword(s):  
Refractive Index ◽  
Optical Properties ◽  
Absorption Coefficient ◽  
Polymer Blend ◽  
Nonlinear Absorption ◽  
Nonlinear Refractive Index ◽  
Nonlinear Optical ◽  
Optical Power ◽  
Copolymer Poly ◽  
Optical Power Limiting

Poly (3 - Hexylthiophene - Co - Thiophene) copolymer was prepared by using the addition polymerization method. The Nonlinear optical properties and the behavior of the optical power limiting of the prepared polymer blend poly (3HT- Co - Th) - PMMA films were studied by using the z - scan technique for different weight ratios of the copolymer poly (3HT- Co - Th). In the present work, a continuous wave (CW) diode - pumped solid - state laser (DPSSL) of wavelengths 532 nm was used for the irradiation of the prepared film samples. The nonlinear optical parameters such as, the nonlinear refractive index (n2), the nonlinear absorption coefficient (β), and the      third - order - nonlinear optical susceptibility (χ (3)) of the polymer blend poly (3HT- Co - Th) - PMMA films were determined for different weight ratios of the copolymer poly (3HT- Co - Th). It is observed that the polymer blend poly (3HT - Co - Th) - PMMA films exhibit saturable absorption (SA) and self - defocusing effects, and this gives an indication that both, the nonlinear refractive index (n2) and the nonlinear absorption coefficient (β), have negative values. The obtained results indicate that the prepared polymer blend poly (3HT - Co - Th) - PMMA films are promising materials and can be considered as suitable materials for different optical and electronic applications.

Z-SCAN DETERMINATION OF THE THIRD-ORDER OPTICAL NONLINEARITY OF ORGANIC DYE NILE BLUE CHLORIDE

2006 ◽  
Vol 20 (11) ◽  
pp. 623-632 ◽  
Author(s):  
QUSAY MOHAMMED ALI ◽  
P. K. PALANISAMY
Keyword(s):  
Refractive Index ◽  
Nonlinear Refractive Index ◽  
Nonlinear Optical ◽  
Nile Blue ◽  
Optical Nonlinearity ◽  
Organic Dye ◽  
Photon Absorption ◽  
Third Order ◽  
Nonlinear Optical Susceptibility ◽  
The Third

The single beam Z-scan technique was used to determine the nonlinear optical properties of the organic dye Nile Blue chloride in the solvent ethanol. The experiments were performed with a He-Ne laser with a wavelength of 632.8 nm. The negative nonlinear refractive index and two-photon absorption coefficient were observed in this dye. The intensity-dependent nonlinear refractive index was investigated. The result shows that the dye exhibits a great nonlinear response with the real and imaginary parts of the third-order nonlinear optical susceptibility χ(3) being -4.12×10-5 esu and 1.35×10-6 esu, respectively. These results show that the Nile Blue chloride dye has potential applications in nonlinear optics.

scholarly journals Nonlinear Refractive Index in Rectangular Graphene Quantum Dots

2019 ◽  
Vol 9 (2) ◽  
pp. 325 ◽  
Author(s):  
Yonggang Qin ◽  
Xiaobo Feng ◽  
Yu Liu
Keyword(s):  
Quantum Dots ◽  
Refractive Index ◽  
Nonlinear Refractive Index ◽  
Nonlinear Optical ◽  
Graphene Quantum Dots ◽  
Third Order ◽  
Nonlinear Optical Susceptibility ◽  
The Third ◽  
Optical Susceptibility ◽  
Wall Boundary Conditions

Alongside its other favorable properties, the large refraction nonlinearity of graphene-related material makes it ideal for use in optoelectronics applications. Numerous experimental studies about nonlinear optical refraction have been conducted, but theoretical verification is lacking. In this paper the nonlinear refractive index for rectangular graphene quantum dots (RGQDs) was calculated using the relationship between nonlinear refractive index and the third-order nonlinear optical susceptibility. The third-order nonlinear optical susceptibility for third harmonic generation was derived employing the electronic states obtained from the Dirac equation around K point in RGQDs under hard wall boundary conditions. Results revealed that the calculated nonlinear refractive index, n 2 , was in the magnitude of 10−14 m2/W in the visible region, which is nearly five orders larger than conventional semiconductor quantum dots, while in the infrared region the nonlinear refractive index reached up to the magnitude of 10−11 m2/W for M = 3M0 sized RGQDs where the resonance enhancement occurred. The nonlinear refractive index could be tuned both by the edges and sizes.

Characterization of nonlinear optical refractive index for graphene oxide–silicon oxide nanohybrid composite

2019 ◽  
Vol 28 (01) ◽  
pp. 1950005 ◽  
Author(s):  
Hamid Darabi ◽  
Mehdi Adelifard ◽  
Yasser Rajabi
Keyword(s):  
Refractive Index ◽  
Optical Properties ◽  
Graphene Oxide ◽  
Nonlinear Refractive Index ◽  
Nonlinear Optical ◽  
Silicon Oxide ◽  
Weight Ratio ◽  
Optical Measurements ◽  
Starting Solution ◽  
Nanohybrid Composite

In this work, Silicon oxide (SiO2) nanoparticles, graphene oxide nanosheet (GO) and GO–SiO2 nanohybrid composites have been synthesized. The role of GO concentration in the starting solution was investigated and correlated to the morphological, structural and optical properties of the studied samples. The structural studies for nanohybrid composites showed that by increasing GO:weight ratio from 0.5 to 2.0, not only does the SiO2 crystalline phase change from cubic to orthorhombic, but the structure of GO also transformed to RGO. The related FESEM images indicate that GO sheets are well-covered by SiO2 nanoparticles with very small grain size and that the accumulation of nanoparticles on each sheet has a high density. Linear Optical measurements showed two optical band gaps of [Formula: see text][Formula: see text]eV and 5.3[Formula: see text]eV for SiO2 nanoparticles, and band gap value of 4.15[Formula: see text]eV for GO nanosheets, which it reduces to 3.3[Formula: see text]eV after formation of the nanohybrid composite with GO: SiO2 weight ratio of 2.0. The nonlinear optical properties of GO–SiO2 with different weight ratio are measured using Z-scan technique. The results showed that the nonlinear refractive index of SiO2 and GO nanoparticles and nanohybrid composite (0.5:1,1:1,2:1) ([Formula: see text]–[Formula: see text]) changed and has a negative sign. It was observed that the nonlinear refractive index changes in different ratios of compounds. Experimental results show that after the formation of the composite, the nonlinear refractive index shows a significant increase in the presence and effectiveness of the GO.

Sign in / Sign up

Export Citation Format

Share Document