scholarly journals Comparison of the effectiveness of Aloe Vera gel with 2% Nitrofurazone ointment on the healing of superficial partial-thickness burns: A randomized clinical trial study

Author(s):  
Parichehr Sabaghzadeh Irani ◽  
Hadi Ranjbar ◽  
Shokoh Varaei ◽  
Sanaz Bostani ◽  
Omalbanin Akbari ◽  
...  

Background & Aim: Routine treatment of burn injuries is dressing with Nitrofurazone ointment. It has several complications, including sensitivity. Aloe Vera is a traditional treatment for wound healing.  This study aimed to compare the effectiveness of Aloe Vera gel with Nitrofurazone ointment in the healing of superficial partial-thickness burns. Methods & Materials: The present study was a split body controlled clinical trial which was carried out on 30 patients with superficial partial-thickness burns. The study was conducted in the Shafa Hospital in Kerman, Iran, in 2016. The sample was recruited from patients who had at least two burns, each burn on an alternate side of the body. On their burns, samples were allocated to two groups that received Aloe Vera gel or 2% Nitrofurazone ointment. Bates-Jensen Wound assessment tool was used to evaluate the healing of burns. Statistical analysis was conducted by SPSS-16 and using the repeated measure ANOVA. Results: The repeated measure ANOVA showed that there was a significant change in the score of BWAT in all areas during the intervention period (p=0.001), but the trend of healing in the two groups during the intervention period was not significantly different (p=0.098). Conclusion: Based on this study, it looks like Aloe vera gel is as effective as 2% Nitrofurazone ointment in healing wounds.

2020 ◽  
Author(s):  
Shokoh Varaei ◽  
hadi ranjbar ◽  
parichehr sabaghzadeh ◽  
sanaz bostani ◽  
Soodabhe amirsalari

Abstract Background: Burn injuries are one of the most common sources of trauma globally that comprise a significant drain on long-term personal and healthcare cost Large surface area burn wounds are difficult to manage and may result in significant physiologic and psychological sequelae. The aim of this study was to compare the effectiveness of Aloe Vera gel with 2%Nitrofurazone ointment in the healing of superficial partial thickness burns wounds. Methods: The present study was a split body controlled, randomized clinical trial. The sample was recruited from patients with superficial partial thickness burns wound who were prescribed to treat with 2% Nitrofurazone ointment. Thirty patients with at least two burn, each burn on an alternate side of the body, entered the study — samples allocated to two area which received Aloe Vera gel or 2% Nitrofurazone ointment on their burns. Bates-Jensen Wound. assessment tool (BWAT) was used to evaluate the healing of burns. the epithelialization parameter and sum score Bates-Jensen tools evaluated before, one, two and three weeks after the beginning of treatment. Results: The mean ± SD of epithelialization parameter in Aloe Vera area were 5.0±00.00, 4.0±46.57, 3.0±50.57, 2.0±56.62. The mean ± SD of epithelialization parameter in 2% Nitrofurazone ointment area were 5.0±00.00, 4.0±66.54, 3.0±76.50, 3.0±03.61.and The mean ± SD of BWAT scores in Aloe Vera area were 30.32 ± 3.28, 27.33 ± 3.38, 21.33 ± 3.13, 16.12 ± 2.16 respectively (F(2, 65.07) =440.00, p=0.001). The mean ± SD of BWAT scores in 2% Nitrofurazone ointment area were 30.51 ± 3.79, 28.45 ± 3.49, 23.36 ± 2.89, 19.23 ± 2.11 ( F(1, 52.00) =228.00, p=0.001).Conclusions: There is a significant difference in epithelialization parameter and (BWAT) scores between intervention and control area. Based on this study it looks like that aloe vera gel could promoted epithelialization and wound closure more effectively than 2% Nitrofurazone ointment


2020 ◽  
Author(s):  
Shokoh Varaei ◽  
Hadi Ranjbar ◽  
Parichehr Sabaghzadeh ◽  
Sanaz Bostani ◽  
Soodabhe Amirsalari

Abstract Background Burn injuries are one of the most common sources of trauma globally that comprise a significant drain on long-term personal and healthcare cost Large surface area burn wounds are difficult to manage and may result in significant physiologic and psychological sequelae . The aim of this study was to compare the effectiveness of Aloe Vera gel with Nitrofurazone ointment in the healing of superficial second-degree burn wounds.Methods The present study was a split body controlled, randomized clinical trial. The sample was recruited from patients with superficial second-degree burn wound who were prescribed to treat with 2% Nitrofurazone ointment. Thirty patients with at least two burn, each burn on an alternate side of the body, entered the study — samples allocated to two groups which received Aloe Vera gel or 2% Nitrofurazone ointment on their burns. Bates-Jensen Wound assessment tool (BWAT) was used to evaluate the healing of burns. The burns were evaluated before, one, two and three weeks after the beginning of treatment.Results The mean ± SD of BWAT scores in Aloe Vera zones were 30.32 ± 3.28, 27.33 ± 3.38, 21.33 ± 3.13, 16.12 ± 2.16 respectively (F(2, 65.07) =440.00, p=0.001). The mean ± SD of BWAT scores in Nitrofurazone ointment zones were 30.51 ± 3.79, 28.45 ± 3.49, 23.36 ± 2.89, 19.23 ± 2.11 (F(1, 52.00) =228.00, p=0.001).Conclusions There is a significant difference in (BWAT) scores between intervention and control groups. Aloe Vera gel was as effective as Nitrofurazone ointment in the treatment of superficial second-degree burns.Trial registration IRCT2014113020151N1. Registered 14 December 2014, https://www.irct.ir/trial/17874


2011 ◽  
Vol 20 (3-4) ◽  
pp. 113-130 ◽  
Author(s):  
Colin Utz-Meagher ◽  
John Nulty ◽  
Lisa Holt

Comparative Analysis of Barefoot and Shod Running This study investigated the biomechanical difference between running barefoot and shod before and after a barefoot training program (BTP). Foot angles at contact (FA), contact time (CT), stride length (SL), initial contact force (ICF), and total peak force (TPF) in shod and unshod runners was analyzed. Fourteen collegiate runners attended 12 total sessions over a two week period. Subjects performed a baseline trial, running eight (10-20 meter) repetitions, four barefoot and four shod, at three different stations; running over a force plate, running in front of a SONY DCR-HC52 video camera (30fps) and running in front of a Casio Exilim Pro EX-F1 camera (300fps). A Post-Test (PT) was conducted at the end of the BTP. A repeated measure ANOVA showed significance (p<.05) in the Test factor, BTP; lowering participants FA mean from 18.8deg+/-.9deg to 5.6deg+/-15.1deg, CT mean from .221m+/-.02m to .2m+/-.03m, and TPF mean from 1427.4N+/-312.9N to 1348.2N+/-269.4N. A repeated measure ANOVA showed significance (p<.05) in the Condition factor (shod vs. unshod); lowering participants FA mean from 23.1deg+/-12.6deg to 1.3deg+/-14.4deg, SL mean from .9m+/-.1m to .8m+/-.1m, and ICF mean from 1465.3N+/- 369.6N to 1324.7N+/-379.4N. Running barefoot and following a BTP alters running biomechanics in ways that may decrease running related injuries.


2020 ◽  
Vol 8 ◽  
Author(s):  
David G Greenhalgh

Abstract Burns to the face affect a part of the body that cannot be hidden and thus exposes potentially major changes in appearance to society. Therefore, it is incumbent upon the caregiver to optimize healing and minimize scarring. The goal for partial-thickness burns is to have them heal within 2–3 weeks to minimize healing time. For full-thickness burns there needs to be strategies to optimize the outcomes for skin grafting and minimize scarring. The goal of this review is to discuss the best way to improve the outcomes of these devastating injuries.


Burns ◽  
2018 ◽  
Vol 44 (8) ◽  
pp. 1982-1988 ◽  
Author(s):  
Ahmed Aboelnaga ◽  
Moustafa Elmasry ◽  
Osama A. Adly ◽  
Mohamed A. Elbadawy ◽  
Ashraf H. Abbas ◽  
...  

2018 ◽  
Vol 29 (1) ◽  
pp. 88-92 ◽  
Author(s):  
Rebeca Pereira de Menezes ◽  
Paula Damasceno Silva ◽  
Pollyana Caldeira Leal ◽  
André Luis Faria-e-Silva

Abstract This study evaluated the effects of tooth bleaching with high-concentration of hydrogen peroxide on alterations of translucency parameter (TP) and color of dentin and enamel. The crown of five human molars was sectioned into four slices parallel to buccal surface. The dentin of external slices containing buccal/ lingual enamel was fully removed with diamond bur; while these slices were used to assess alterations on enamel. Alterations on dentin were assessed into the center of internal slices. The color of specimens was measured over white and black backgrounds using a spectrophotometer (CieL*a*b) at baseline, allowing to calculate the TP by difference between the color measured over each background. Specimens were submitted to three 15-min applications of 35% hydrogen peroxide followed by their storage in water for one-week. Afterwards, the color measurements were repeated at both backgrounds. Color (∆L, ∆a, ∆b and ∆E) and translucency (∆TP) changes were calculated and data individually analyzed by T-test (α = 0.05). Influence of hard tissue and assessment time on each color parameter was also analyzed by 2-way repeated measure ANOVA (α = 0.05). Tooth bleaching resulted in increased lightness for the enamel, whereas no alteration on this parameter occurred for dentin. No difference between the tooth hard tissues was observed regards the other color parameters and ∆E. A slightly reduction on TP was observed only for the enamel. In conclusion, 35% hydrogen peroxide caused similar color and translucency changes on dentin and enamel.


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