A Review on Prevention, Transmission and Symptoms of the Covid-19

Author(s):  
Hamid Mohammadi ◽  
Yahya Ehteshaminia ◽  
Seif Ali Mahdavi

Introduction: Coronavirus belongs to a family of viruses that can cause symptoms such as pneumonia, fever, shortness of breath and lung infection. On December 29, 2019, the World Health Organization (WHO) coined the term New Coronavirus 2019 to refer to a coronavirus that affects the lower respiratory tract of patients with pneumonia in Wuhan, China. The new coronavirus was first identified in Wuhan, among a number of patients with an unknown form of viral pneumonia who also had a history of Huanan seafood market. Materials and Methods: In this study, the websites of PubMed, Google Scholar, SID, and Magiran were searched and related articles were reviewed. Results: Symptoms of COVID-19 occur after a period of 2 to 10 days and the period of symptoms resulting in death of patients varied between 6 to 41 days. Common symptoms at the onset of the disease are fever, cough, and fatigue. Each carrier is reported to infect an average of 3.77 others. Conclusion: Regarding the way of transmission of viral diseases of the upper respiratory tract, such as COVID-19, i.e., the transmission by respiratory droplets as well as close communication between individuals, solutions have been recommended by experts. Researchers are suggesting not touching the T-zone on the face, using a mask and following the principles of social distancing are the most effective ways to control the disease. Due to the lack of definitive treatment or effective vaccine for COVID-19 so far, following these principles has a significant role in combating this pandemic.

Author(s):  
Soumik Chatterjee ◽  
Sabyasachi Chatterjee

Novel Coronavirus are very harmful virus. This viruses have positive single stranded RNA genome and enveloped which is called nucleocapsid. The family of this virus is Coronaviridae. This virus originated from species of avian and mammalian. This virus effect on upper respiratory tract in humans. Many species of these novel coronaviruses (HCoVs) are named as HCoV-HKU1, HCoV-NL63. Predominant species of this virus is Middle East respiratory syndrome (MERS-CoV) across the world.  In both adults and childrens HCoV-HKU1 sp. is causes for chronic pulmonary disease and HCoV-NL63 species causes for upper and lower respiratory tract disease. Most recent species of this virus is MERS-CoV. This species caused for acute pneumonia and occasional renal failure. The new strain of novel Coronavirus is SARS-CoV-2. This strain causes for the Coronavirus Disease 2019 (COVID-19). This disease named by the World Health Organization. Now world fighting against COVID-19 and according to the recent statistics report of world about the COVID-19 cases approx 22.6M confirmed cases and 792K death cases appeared and recovered 14.5M. COVID-19 disease starts to spread from December 2019 from china. Covid-19 disease is emerged in Wuhan seafood market at Wuhan of South China and then rapidly spread throughout the world. The corona virus outbreak has been declared a public health emergency of International concern by World Health Organization (WHO). In this article we summarize the current clinical characteristics of coronavirus and diagnosis, treatments and prevention of COVID-19 disease. In this review article, we analyze data from various Research Reports like WHO guidelines and other articles. It is very important to the readers that new data of COVID-19 updating nearly every hour of day regarding clinical characteristics, diagnosis, treatment strategies, and outcomes COVID-19 disease. The degree of COVID-19 disease varying throughout the world. COVID-19 affected patient shows various symptoms like fever, cough, sore throat, breathlessness, fatigue, and malaise among others. The COVID-19 disease is being treated through general treatment like symptomatic treatment, by using antiviral drugs, oxygen therapy and by the immune system. There is no vaccine or therapeutic strategies for deal with this disease yet. In this critical situation preventive measures must be require.  A very important issue in preventing viral infection is hand hygiene. There are other entities that people can boosting the immune system and help in infection prevention.


2021 ◽  
Author(s):  
Pinar Kiymet Karataban

Coronavirus (COVID-19) is an enveloped RNA virus with a size of ~350 kilobase-pair and COVID-19 is commonly transmitted via aerosols, saliva, nasal droplets, and surface contact which causes severe acute respiratory tract infection among infected humans, and recently many cases declared with severe blood clotting. The average incubation period ranges from 4 to 14 days. The infected person usually presents fever accompanying an upper respiratory tract infection (RTI) and complaints of dry cough, and dyspnea. It is highly recommended to keep any suspected individuals in quarantine (isolation). After its first emergence in Wuhan, China in 2019 and then intercontinental spread it was declared as a pandemic by the World Health Organization in March 2020. The pandemic of COVID-19 deeply affected the whole world and healthcare workers as front liners are most at risk among professional groups. Dentistry is among the riskiest occupational groups that include all direct and indirect ways of COVID-19 spread. In this process, the dentists who experienced the effects of COVID-19 in the working conditions, economy, and social fields were psychologically negatively affected, and their anxiety, fear, and stress levels increased. In this review, we discuss the increased risk of the spread of coronavirus during dental operative procedures and the effects of the COVID-19 pandemic on the anxiety level, depression, and mental health of dental professionals.


2021 ◽  
Vol 42 ◽  
Author(s):  
Hanieh Beyrampour-Basmenj ◽  
Morteza Milani ◽  
Abbas Ebrahimi-Kalan ◽  
Ziyad Ben Taleb ◽  
Kenneth D Ward ◽  
...  

Background: In late December 2019, a new infectious respiratory disease (COVID-19) was reported in a number of patients with a history of exposure to the Huanan seafood market in China. The World Health Organization officially announced the COVID-19 pandemic on March 11, 2020. Here, we provided an overview of the epidemiologic, diagnostic and treatment approaches associated with COVID-19.Methods: We reviewed the publications indexed in major biomedical databases by December 20, 2020 or earlier (updated on May 16, 2021). Search keywords included a combination of: COVID-19, Coronavirus disease 2019, SARS-CoV-2, Epidemiology, Prevention, Diagnosis, Vaccine, and Treatment. We also used available information about COVID-19 from valid sources such as WHO.Results and Conclusion: At the time of writing this review, while most of the countries authorized COVID-19 vaccines for emergency use starting December 8, 2020, there is no a definite cure for it. This review synthesizes current knowledge of virology, epidemiology, clinical symptoms, diagnostic approaches, common treatment strategies, novel potential therapeutic options for control and prevention of COVID-19 infection, available vaccines, public health and clinical implications.


Author(s):  
KRISHNANJANA S. NAIR ◽  
SHIVALI KAMATH ◽  
ARYA RAJAN ◽  
SACHIN THOMAS ◽  
ASWIN D. ◽  
...  

In December 2019, a rare case of pneumonia was reported in Wuhan, China. This was later analyzed and known to have similar characteristics as viral pneumonia caused by a novel coronavirus. Later, on 11 February 2020, the World Health Organization (WHO) officially named the disease as COVID19. The Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) ought to taint both the upper respiratory tract and the lower respiratory tract. This COVID-19 is spreading quickly with an immense rise in cases around the world. This infection's mechanism stays obscure, and the medications explicit for the infection were not grown at this point. Infection is highly contagious. Severe Acute Respiratory Syndrome Coronavirus 2(SARS-CoV-2) is one of seven kinds of crown infection, including the one which causes severe maladies like Middle East respiratory disorder (MERS) and abrupt, intense respiratory syndrome(SARS). Since its revelation, the infection has spread and has caused anxiety and fear among people. Recent vaccines are tracked, and clinical trials can bring an immediate protocol on a medication approach. By including different therapeutic approaches, it is easier to combat the disease quickly. With very low mortality and high transmission rate, new approaches to vaccines and nanomedicines bring down the spread. Controlled patient care is also crucial. On 11 March, the World Health Organization (WHO) declared the disease as 'global pandemic’. COVID-19, therefore, poses a significant threat to global public health. This article reviews the epidemiology, pathogenesis, and diagnostic methods. The review also focuses on repurposed drugs, traced vaccines, and a quick view of prophylactic nanomedicines as an alternative for COVID 19. For this review, the complete database has been collected from various search engines such as PubMed, ScienceDirect, Scopus, Elsevier, etc., from the year 2001-2020 using the following keywords.


Author(s):  
Napolitano Gavino ◽  
Fanizzi Silvia ◽  
Cesa Simonetta

On January 12, 2020, the World Health Organization (WHO) declared Covid-19 an emergency of international interest. The first documented case in the "Pope John XXIII" Hospital in Bergamo was identified on Friday, February 21, 2020. The ASST Pope John XXIII of Bergamo was among the very first Hospital Companies to implement a series of organizational remodelling to quickly face the health emergency from the Sars-Cov-2 outbreak. In this context, we will describe the role and organizational changes adopted by the Complex Operating Unit (UOC) Microbiology and Virology. Laboratory diagnostics can effectively help counteract this and other (future) viral outbreaks. Molecular diagnostics is the only method currently recommended for the identification of infectious cases. The gold-standard method for identifying the virus is Real-time PCR (RT-PCR) according to both the protocol of the Charitè University Hospital in Berlin and the American CDC (Center for Disease Control and Prevention). Biological samples of the lower respiratory tract (sputum, endotracheal aspirate, or broncho-alveolar washing) or alternatively upper respiratory tract samples are preferred for the execution of a swab for each nostril and a swab for each side of the oropharyngeal cavity. The need to adopt a new organizational structure also concerned the UOC Microbiology and Virology, which was quickly called upon to cope with the health emergency by making its contribution through molecular research of the Sars-Cov-2 virus. We will illustrate the salient phases of the reorganization that led to the execution of over 1000 molecular swabs per day and the implementation of a service in H24. Properly managing human resources in the 24 hours was essential for the proper functioning of the laboratory itself and to deal with the ongoing health emergency. In this even evolving and uncertain context, it was difficult to adopt predefined strategies, but the right involvement, the self-denial of the staff and the strong team spirit have made it possible to achieve excellent performance and quality results.


2020 ◽  
pp. 276-289
Author(s):  
Mobina Fathi ◽  
Kimia Vakili ◽  
Niloofar Deravi

Around the end of December 2019, a new beta-coronavirus from Wuhan City, Hubei Province, China began to spread rapidly. The new virus, called SARS-CoV-2, which could be transmitted through respiratory droplets, had a range of mild to severe symptoms, from simple cold in some cases to death in others. The disease caused by SARS-CoV-2 was named COVID-19 by WHO and has so far killed more people than SARS and MERS. Following the widespread global outbreak of COVID-19, with more than 132758 confirmed cases and 4955 deaths worldwide, the World Health Organization declared COVID-19 a pandemic disease in January 2020. Earlier studies on viral pneumonia epidemics has shown that pregnant women are at greater risk than others. During pregnancy, the pregnant woman is more prone to infectious diseases. Research on both SARS-CoV and MERS-CoV, which are pathologically similar to SARS-CoV-2, has shown that being infected with these viruses during pregnancy increases the risk of maternal death, stillbirth, intrauterine growth retardation and, preterm delivery. With the exponential increase in cases of COVID-19 throughout the world, there is a need to understand the effects of SARS-CoV-2 on the health of pregnant women, through extrapolation of earlier studies that have been conducted on pregnant women infected with SARS-CoV, and MERS-CoV. There is an urgent need to understand the chance of vertical transmission of SARS-CoV-2 from mother to fetus and the possibility of the virus crossing the placental barrier. Additionally, since some viral diseases and antiviral drugs may have a negative impact on the mother and fetus, in which case, pregnant women need special attention for the prevention, diagnosis, and treatment of COVID-19.


2019 ◽  
Vol 1 (1) ◽  
pp. 72-81
Author(s):  
Hamidreza Shirzadfar ◽  
Narsis Gordoghli

In recent years, chronic medical problems have become increasingly prevalent. Chronic ‎illnesses challenge the view of life as a regular and continuous process, a challenge that has ‎important psychological consequences. The long duration of people suffering from these ‎diseases, the long process of treatment and the fact that there is no proper and definitive ‎treatment for most of these diseases and their associated complications have made chronic ‎diseases a detrimental factor in public health. According to the World Health Organization ‎‎(2006), the prevalence of chronic and non-communicable diseases is increasing in all countries, ‎especially developing countries, so that the major challenge for the health system in the present ‎century, is not living people, but better adapted to chronic illnesses and maintaining their ‎mental and social health and well-being Ed's life-threatening chronic physical illness.‎ Chronic pain is a pain that lasts longer than usual, and according to the criteria of the ‎International Association of Pain, this time is defined as at least 3 months to 6 months. Chronic ‎pain is such that not only faced the sick person whit the pressure of the pain but also with many ‎other pressure that affect different parts of her life. Fibromyalgia is one of the most rheumatologic disorders and one of the most resistant chronic ‎pain syndromes. Fibromyalgia is one of the most common musculoskeletal disorders in adults ‎and chronic pain is one of the most common complaints in this group of patients.


Author(s):  
Petr Ilyin

Especially dangerous infections (EDIs) belong to the conditionally labelled group of infectious diseases that pose an exceptional epidemic threat. They are highly contagious, rapidly spreading and capable of affecting wide sections of the population in the shortest possible time, they are characterized by the severity of clinical symptoms and high mortality rates. At the present stage, the term "especially dangerous infections" is used only in the territory of the countries of the former USSR, all over the world this concept is defined as "infectious diseases that pose an extreme threat to public health on an international scale." Over the entire history of human development, more people have died as a result of epidemics and pandemics than in all wars combined. The list of especially dangerous infections and measures to prevent their spread were fixed in the International Health Regulations (IHR), adopted at the 22nd session of the WHO's World Health Assembly on July 26, 1969. In 1970, at the 23rd session of the WHO's Assembly, typhus and relapsing fever were excluded from the list of quarantine infections. As amended in 1981, the list included only three diseases represented by plague, cholera and anthrax. However, now annual additions of new infections endemic to different parts of the earth to this list take place. To date, the World Health Organization (WHO) has already included more than 100 diseases in the list of especially dangerous infections.


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