Analyze the Outbreak of COVID-19 in Wuhan City Based on Large-Scale Events and Extreme Weather

This article analyzes the impact of large-scale mass activities and extreme weather on the outbreak of COVID-19 in Wuhan, confirming that the South China Seafood Market is indeed the origin of the Wuhan epidemic, and found that the probability of respiratory transmission is low in open space, while food transmission is possible. At the same time, it was found that the outbreaks of SARS in Beijing in 2003 and COVID-19 in Wuhan in 2019 were both related to extreme weather. By investigating genomics and epidemiological data, it was determined that the first COVID-19 case in Wuhan was in November, and the beginning of the epidemic was in late November. Comparing the climate of November, December and January in Wuhan from 2011 to 2020, it is found that there are a lot of extreme weather events in Wuhan from the end of 2019 to the beginning of 2020, including strong winds, heavy rains, large cooling after continuous high temperature, and continuous low temperature and rainy after large cooling, the temperature suddenly rises and then drops rapidly, the wind continues to weaken for many days and then suddenly increases, and long rainy days, etc.

Pharma Giant Expects Vaccines Lineup to Be Its Top Seller This Year

Coronavirus (COVID-19) was first seen in late December in Hubei province of Wuhan city in China. The highly contagious disease, caused by a virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is transmitted from humans to humans. After the first case in Wuhan, the disease rapidly spread to other parts of the globe.

Đánh giá nồng độ lactate và procalcitonin ở bệnh nhân Covid-19

TÓM TẮT Đặt vấn đề: Bệnh COVID-19 đa dạng từ không có triệu chứng đến có các triệu chứng nhẹ cho đến viêm phổi nặng, hội chứng suy hô hấp cấp tiến triển (ARDS), nhiễm khuẩn huyết suy đa tạng và tử vong. Người cao tuổi, người có bệnh mạn tính sẽ có nguy cơ diễn biến nặng nhiều hơn. Nghiên cứu này nhằm xác định nồng độ lactate và PCT ở những bệnh nhân Covid-19 và xét mối liên quan giữa lactate và PCT trên bệnh nhân Covid-19. Đối tượng và phương pháp: Nghiên cứu mô tả cắt ngang trên 126 bệnh nhân được chẩn đoán nhiễm Sars-Cov-2 bằng xét nghiệm RT PCR. Kết quả: Tuổi trung bình 55,98 ± 17,1 tuổi (4 - 98 tuổi). Bệnh nhân > 60 tuổi chiếm tỉ lệ cao nhất (42,8%). Trung vị PCT: 3,6 (95%CI:3,21 - 3,75) ng/ml; trung vị lactate 1,5 (95%CI:1,21 - 1,91) mmol/L; lactate có tương quan thuận và yếu với procalcitonin với r = 0,241; p < 0,001. Nồng độ procalcitonin > 0,1 ng/ml; lactate > 2 mmol/l ở bệnh nhân Covid-19 chiếm tỷ lệ cao với 89,7% và 39,7%. Kết luận: Chỉ điểm procalcitonin, lactate tăng cao ở bệnh nhân Covid-19. ABSTRACT ASSESSMENT OF SERUM LEVEL OF LACTATE AND PROCALCITONIN IN COVID-19 PATIENTS Background: Sars-CoV-2 has been identified as the cause of acute respiratory infections in Wuhan city, Hubei province, China, and has since spread worldwide. Sars-CoV-2 is capable of aerosol transmission in enclosed, crowded, and poorly ventilated spaces. COVID-19 illness ranges from asymptomatic to mild symptoms to severe pneumonia, acute respiratory distress syndrome (ARDS), sepsis, multiple organ failure, and death. This study aims to determine lactate and PCT levels in Covid-19 patients and examine the relationship between lactate and PCT in Covid-19 patients. Methods: A cross-sectional study was performed on 126 patients diagnosed with Sars-Cov-2 infection by RT-PCR. Results: Mean age was 55.98 ± 17.1 years (range: 4-98 years). Patients more than 60 years old were accounted for the highest rate (42.8%). Median PCT: 3.6 (95%CI:3.21 - 3.75) ng/ml; median lactate 1.5 (95%CI:1.21 - 1,91) mmol/L; lactate has a positive and weak correlation with procalcitonin with r = 0.241; p < 0.001. Procalcitonin concentration > 0.1 ng/ml; lactate > 2 mmol/l in patients with Covid-19 accounted for a high rate with 89.7% and 39.7%. Conclusion: Serum level of procalcitonin and lactate raise highly in Covid-19 patients. Keywords: Covid-19, procalcitonin, lactate.

COVID like illness versus COVID-19 (CLIC STUDY) – Clinical profile and outcome

Background: In December 2019, several cases of acute respiratory illness were detected in Wuhan city of China. This SARS-CoV-2 has been rapidly spreading worldwide ever since. SARS-CoV-2 has the potential to damage the vital organs such as lung, heart, liver, and kidney, and infection poses a considerable risk to patients by the high prevalence of pneumonia. Aims and Objectives: The objectives of the study are as follows: (1) To study clinical profile and biochemical markers in SARI patients. (2) To compare the clinical profile and biochemical markers between SARS-CoV-2 positive and negative patients and their outcomes. Materials and Methods: The present study is a hospital-based prospective cross-sectional study conducted on a total of 350 patients (150 SARI+200 COVID-19) in Bengaluru during the study period from June 2020 to May 2021. Results: Diabetes mellitus was present in 30% of SARI and 42% in COVID-19 patients (P=0.03). Leukocytosis (Total Leukocyte Count [TLC] >11000 cells/mm3) was more common among SARI patients than COVID-19 patients (49.3% vs. 24.3%). Leukopenia (TLC <4000 cells/mm3) was significantly more common in COVID-19 patients than in SARI patients (10.2% vs. 3.6%, P<0.001). Conclusion: COVID-19 infection is more common in patients with comorbidities such as diabetes mellitus and hypertension than SARI. Leukopenia was more common in COVID-19 patients whereas leukocytosis was more common in SARI patients.

Management Strategies for Oral & Maxillofacial Surgery Amid the COVID-19 Pandemic

The novel-coronavirus (2019-nCOV) emerged in Wuhan City in December 2019, this resulted in a quick and catastrophic health problem all over the world but our country is slightly less affected by the pandemic. There could be a number of reasons for less numbers of Covid positive cases and lack of awareness and reduced Covid testing capacity and hence less mortality in Pakistan. In order to provide assistance to an ever increasing number of infected patients and, at the same time taking care of urgent maxillofacial conditions. This manuscript gives the reader in a nutshell the overall surgical experience of oral and maxillofacial practice at Aga Khan University Hospital, Karachi, Pakistan in the COVID-19 pandemic and would like to provide a number of recommendations that would assist the scheduling process of surgical management during the COVID-19 pandemic and reduce the risk of infection among healthcare workers and others involved with the service. KEYWORDS: Maxillofacial surgery; Coronavirus; COVID-19; Pandemic

Yoga: A Natural Vaccine against COVID 19

The most shocking situation which is the cause of sorrow for the whole universe is Covid-19. This virus was first detected in Wuhan City, China. This pandemic has shown its ramification on us in different ways and in different ways in this world. We are recently facing the second wave of Covid-19. Till the date there is no full proof medicine for corona virus (SARS-CoV-2), but scientists around the world have succeeded in developing some vaccines which would help to protect us against the deadly virus (SAR-CoV-2). It is very much important for us to improve our physical as well as mental conditions, the best way to do so is by doing physical exercises, yoga , maintain proper diet, drinking plenty of water and maintain distance from others. Covid-19 mostly affects our lungs. People experience physical problems like breathing problem , chest pain, cold, fever etc. due to covid , and those people having serious symptoms are more prone to death. Yoga is one of the best way for improving the immunity as prescribed by several doctors, scientists, virologists and even by the scientists of WHO. Many Researches have been conducted and it shows yoga improves immunity, improves respiratory competence, mental power and increases body’s strength which is very much essential to fight against covid virus. In this study focus has been given on the importance of yoga in fighting against covid.

A Review on Coronavirus

Coronavirus disease also termed as covid-19 or SARS-COV-2 infection has been declared as global pandemic disease by World Health Organization (WHO). The first case of covid-19 is reported at the local Huanan Seafood wholesale market in Wuhan city in Hubei in central chain at last of 2019. Covid-19 is rapidly spread throughout the world since December – 2019 from Wuhan city of China. Covid-19 patient has various symptoms like fever, cough, sore throat, breathlessness, fatigue and others. It is very necessary to identify the cases of covid-19 as soon as possible and isolate the suspected people and confirmed cases of Covid-19 to prevent the infection to other peoples.

Analysis for the Interaction Relationship between Urbanization and Ecological Security: A Case Study in Wuhan City Circle of China

Exploring the interaction relationship between urbanization and ecological security is the key issue to achieve regional sustainable development. This study used coupling coordination model and vector auto-regression model to comprehensively investigate the interaction relationship between urbanization and ecological security in Wuhan City Circle from 2005 to 2018. The results showed that urbanization quality in Wuhan City Circle increased from 0.1818 in 2005 to 0.4355 in 2018, with an average annual increase rate of 10.74%. The ecological security of Wuhan City Circle decreased from 0.4890 in 2005 to 0.4511 in 2015 and increased from 0.4511 in 2015 to 0.4554 in 2018. The degree of coupling coordination between urbanization and ecological security of Wuhan City Circle presented a circle structure with Wuhan as the center and increasing outward. Additionally, the impulse analysis showed that the increase of urbanization had a significant negative impact on ecological security of Wuhan city, Huangshi city, and Xiaogan city. Meanwhile, the ecological security index of Ezhou city, Tianmen city, Huanggang city, Xiantao city, Xianning city, and Qianjiang city were all positive in early stage after the ecological security was impacted by the increase of urbanization. The analysis of historical data and future trends can provide operable recommendations for urbanization development and ecological security protection through cleaner production and efficient use of natural resources from the aspect of coordinated development.