scholarly journals Risk Factors and Short Term Outcome of Hypoxic Ischemic Encephalopathy in Term Neonates with Perinatal Asphyxia

2016 ◽  
Vol 04 (10) ◽  
pp. 13311-13316 ◽  
Author(s):  
Sonia Rosalind Martina. S
Keyword(s):  
Risk Factors ◽  
Perinatal Asphyxia ◽  
Hypoxic Ischemic Encephalopathy ◽  
Short Term ◽  
Term Outcome ◽  
Term Neonates ◽  
Short Term Outcome ◽  
Ischemic Encephalopathy

Clinical Profile and Short-Term Outcome of Neonatal Seizures in a Tertiary Care Hospital, Kuppam – A Retrospective Study

2021 ◽  
Vol 8 (27) ◽  
pp. 2381-2386
Author(s):  
Poojitha Kancherla ◽  
Harsha P.J. ◽  
Gowtham R. ◽  
Dowlath Anwar Basha ◽  
Chandran G.P ◽  
...  
Keyword(s):  
Tertiary Care ◽  
Clinical Profile ◽  
Hypoxic Ischemic Encephalopathy ◽  
Care Hospital ◽  
Neonatal Seizures ◽  
Metabolic Disturbances ◽  
Short Term ◽  
Term Outcome ◽  
Short Term Outcome ◽  
Ischemic Encephalopathy

BACKGROUND Neonates presenting with seizures require long term stay in hospital and have higher chances of neuro-developmental delay later. Seizures in neonates are mostly subtle and difficult to diagnose. We wanted to study the clinical profile and short-term outcome on term and later pre-term neonates presenting with seizures. METHODS The study was a retrospective observational study done from November to December 2020 at PES Hospital, Kuppam. Retrospective data of neonatal seizures from May 2019 to April 2020 was considered for study. Details from the case records of neonates with seizures was collected. RESULTS Neonatal seizures (NS) were most common in females (53.8 %, 72/134). Subtle seizures were most common form of seizures in neonates which was seen in 64.2 % (86/134) babies followed by tonic seizures in 22.4 % (30/134). Neonatal seizures were most commonly seen in babies with hypoxic ischemic encephalopathy in 63.4 % (85/134) followed by metabolic disturbances in 15.6 % (21/134) and meningitis in 13.5 % (18/134). In babies with hypoxic ischemic encephalopathy, metabolic and meningitis subtle seizures were observed to be more common. Seizures were seen most commonly in first 72 hours of life (82.85 %, 111/134). Seizures in babies with hypoxic ischemic encephalopathy, metabolic causes most commonly occurred within first 24 hours of birth. Seizures in babies with meningitis most commonly occurred after 7 days of birth. Babies with neonatal seizures with sequelae was seen in 17.96 % (24/134) and 11.94 % babies died (16/134). CONCLUSIONS Subtle seizures were most common form and hypoxic ischemic encephalopathy was most common risk factor. Most neonatal seizures present within 72 hours of birth. Babies with meningitis presented with seizures most commonly after 72 hours of birth. KEYWORDS Hypoxic Ischemic Encephalopathy, Neonatal Seizures, Newborn, Aetiology, Outcome

scholarly journals CLINICAL PROFILE AND SHORT TERM OUTCOME OF HYPOXIC ISCHEMIC ENCEPHALOPATHY AMONG BIRTH ASPHXIATED BABIES IN A TERTIARY CARE HOSPITAL

2021 ◽  
Vol 71 (1) ◽  
pp. 24-28
Author(s):  
Hafsa Niaz ◽  
Jawad Jalil ◽  
Qamar Zaman Khan ◽  
Faisal Basheer ◽  
Shahzad Akhtar ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Birth Asphyxia ◽  
Clinical Profile ◽  
Hypoxic Ischemic Encephalopathy ◽  
Care Hospital ◽  
Short Term ◽  
Term Outcome ◽  
Short Term Outcome ◽  
Ischemic Encephalopathy ◽  
Grade Iii

Objective: To determine the clinical profile, selected antepartum and intrapartum risk factor for adverse shortterm outcomes of hypoxic ischemic encephalopathy in babies with birth asphyxia. Study Design: Cross sectional study. Place and Duration of Study: Neonatal Intensive Care Unit of Pak Emirates Military Hospital, Rawalpindi, fromJan to Dec 2018. Methodology: This study including all birth asphyxiated babies born who fulfilled the inclusion criteria.Following data was collected prospectively regarding gender, gestational age, birth weight and mode of delivery, maternal age, antenatal follow up, history of premature rupture of membranes and meconium stained liquor. Babies were categorized into different stages of hypoxic ischemic encephalopathy according to Sarnat and Sarnat staging. Selected antepartum and intrapartum risk factors leading to hypoxic insult at birth were studied and short-term outcome was recorded in the form of need of mechanical ventilation, mortality and discharge from the hospital.Results: The frequency of birth asphyxia turned out to be 122/5986 (2.03%) at our center. Thirty four (27.87%)required mechanical ventilation, mortality was recorded at 20/122 (16.39%). While 61 (50%) babies suffered from stage I hypoxic ischemic encephalopathy, 13/20 (65%) of newborn who expired were suffering from grade III hypoxic ischemic encephalopathy. Conclusion: The severity of hypoxic ischemic encephalopathy affects the outcome of newborns having birthasphyxia with hypoxic ischemic encephalopathy grade III associated with maximum mortality. Early identifycation of pregnancies at risk for asphyxia, with appropriate intervention in selected cases is the key to prevent birth asphyxia and its ensuing neonatal complications.

Incidence, risk factors, etiology, severity and short-term outcome of non-traumatic intracerebral hemorrhage in young adults

2014 ◽  
Vol 22 (1) ◽  
pp. 123-132 ◽  
Author(s):  
R.-J. Koivunen ◽  
J. Satopää ◽  
A. Meretoja ◽  
D. Strbian ◽  
E. Haapaniemi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Young Adults ◽  
Intracerebral Hemorrhage ◽  
Short Term ◽  
Term Outcome ◽  
Short Term Outcome ◽  
Incidence Risk

scholarly journals Hemophagocytic Lymphohistiocytosis: Prevalence, Risk Factors, Outcome, and Outcome-related Factors in Adult Idiopathic Inflammatory Myopathies

2019 ◽  
Vol 47 (10) ◽  
pp. 1532-1540 ◽  
Author(s):  
Junyu Liang ◽  
Danyi Xu ◽  
Chuanyin Sun ◽  
Weiqian Chen ◽  
Heng Cao ◽  
...  
Keyword(s):  
Risk Factors ◽  
Disease Activity ◽  
Case Control Study ◽  
Case Control ◽  
Short Term ◽  
Related Factors ◽  
Term Outcome ◽  
Factors Influencing ◽  
Short Term Outcome ◽  
Control Study

Objective.To clarify the prevalence, risk factors, outcome, and outcome-related factors of hemophagocytic lymphohistiocytosis (HLH) in patients with dermatomyositis (DM), polymyositis (PM), or clinically amyopathic dermatomyositis (CADM).Methods.Data of patients with DM, PM, or CADM who were admitted to the First Affiliated Hospital of Zhejiang University from February 2011 to February 2019 were retrospectively collected. Patients diagnosed with HLH constituted the case group. A 1:4 case-control study was performed to identify risk factors for HLH in patients with DM, PM, or CADM through comparison, univariate, and multivariate logistic regression analysis. Intragroup comparison was made among patients with HLH to identify factors influencing unfavorable short-term outcome.Results.HLH was a rare (4.2%) but fatal (77.8%) complication in patients with DM, PM, or CADM. The retrospective case-control study revealed that higher on-admission disease activity (p = 0.008), acute exacerbation of interstitial lung disease (AE-ILD, p = 0.002), and infection (p = 0.002) were risk factors for complication of HLH in patients with DM, PM, or CADM. The following intragroup comparison showed that higher on-admission disease activity (p = 0.035) and diagnosis of CADM (p = 0.039) might influence the short-term outcome of patients with HLH. However, no risk factor was identified after false discovery rate correction.Conclusion.In this study, secondary HLH was a fatal complication, with higher on-admission disease activity, AE-ILD, and infection working as risk factors. The underlying role of infection and autoimmune abnormality in HLH in connective tissue disease was subsequently noted. Clinical factors influencing the short-term outcome of patients with secondary HLH require further study.

scholarly journals To study the short term outcome and risk factors for premature neonate born at Dr. Bhimrao Ambedkar Memorial Hospital, Raipur, CG

2020 ◽  
Vol 7 (4) ◽  
pp. 166-173
Author(s):  
Dr. Sharja Phuljhele ◽  
◽  
Dr. Prachi Bichpuria ◽  
Dr. Samreen Yusuf ◽  
Dr. Abha Singh ◽  
...  
Keyword(s):  
Risk Factors ◽  
Premature Neonate ◽  
Memorial Hospital ◽  
Short Term ◽  
Term Outcome ◽  
Short Term Outcome

scholarly journals Maternal Risk Factors, Clinical Profile and Short-Term Outcome of Pre-Term Low Birth Weight Babies

KYAMC Journal ◽  
2020 ◽  
Vol 11 (2) ◽  
pp. 77-82
Author(s):  
Mosammat Afroza Jinnat ◽  
Shafi Ahmed ◽  
Sirajum Monira ◽  
Muhammad Mozammel Haque ◽  
Mashura Musharraf ◽  
...  
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Maternal Risk Factors ◽  
Short Term ◽  
Term Outcome ◽  
Maternal Risk ◽  
Short Term Outcome ◽  
Low Birth Weight Babies ◽  
Neonatal Ward

Background: Preterm Low Birth Weight babies carry relatively higher risk of perinatal and neonatal mortality, retarded growth and development subsequently. In this study, some maternal risk factors were investigated as it seems to be important to study these factors on regional basis. Objective: To find out the maternal risk factors, clinical profile and short term outcome of pre-term low birth weight neonates by gestational age, birth weight, Occipitofrontal Circumference, length, different presentation (asphyxia, hypothermia, feeding difficulties, signs of infection) on admission and the morbidity and mortality of preterm LBW. Materials and Methods: A descriptive type of cross sectional study was done in neonatal ward of Jalalabad Ragib Rabeya Medical College Hospital, Sylhet from May, 2015 to April, 2016. Hundred cases were selected from neonatal ward and 100 controls were selected from obstetrics ward. Results: Among 100 pre-term LBW neonates, 52 were male and 48 were female. Only 22% mother took regular antenatal check up in case group and 55% in control group. Mean gestational age of neonates were 33.3±2.1 weeks. Important risk factors were primi parity (58% in cases vs 34% in control), hypertension (19% vs 5%), pre-eclampsia (26% vs 12%), prolonged rupture of membrane (33% vs 7%), APH (22% vs 0%), acute infection (8% vs 1%), multiple birth (17% vs 2%). Common clinical presentations were prematurity and LBW. Commonest morbidity was feeding problem (70%). The overall survival rate was 87%. Most common cause of death was septicemia (30%). Conclusion: all the identified risk factors were significantly higher in pre-term LBW babies than those of control. KYAMC Journal Vol. 11, No.-2, July 2020, Page 77-82

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