scholarly journals Growth and Neurodevelopmental Outcome of Very Low Birth Weight Babies at 1 Year of Age

2017 ◽  
Vol 05 (06) ◽  
pp. 23836-23840
Author(s):  
Dr Radhika. S ◽  
2016 ◽  
Vol 7 (5) ◽  
pp. 61-69
Author(s):  
Somen Sur ◽  
Subhasis Das ◽  
Soumitra Masani

Background: Very low birth weight babies are very fragile in nature and usually undergone through stormy neonatal period, which affects significantly their neurodevelopmental outcome in long term basis.Aims and Objectives: 1. Assessment of neurodevelopmental outcome in very low birth weight (VLBW) babies at 12 month corrected gestational age. 2. Study of risk factors associated with such outcome.Materials and Methods: VLBW babies without any major congenital anomaly were included in this study. They were followed up in high risk clinic upto 12 month corrected gestational age. In follow up visits, assessment of tone was done by Amiel Tiesonmethod and 180 degree flip test. Developmental screening was done by Denver Developmental Screening Test (DDST II).Data obtained from this study were entered in Microsoft Excel and subsequently analysed with the help of Epi Info (TM) 3.5.3 software.Results: 24.4% among the study population showed neurodevelopmental abnormalities. Of them, 22.2% VLBW infants had muscle tone abnormality; 15.6% were suspect in gross motor development, 8.9% were suspect in fine motor, 11.1% were suspect in personal – social and 8.9% were suspect in language development, which were statistically significant. On assessment of risk factors, it was found that low birth weight, prematurity, non-use of antenatal corticosteroid, hypoglycaemia, intraventricular haemorrhage, sepsis, jaundice, mechanical ventilation, intra uterine growth retardation were significantly associated with various strata of neurodevelopmental outcome.Conclusion: VLBW babies are very prone to develop neurodevelopmental complications. Taking proper care regarding above said risk factors can reduce such complications. Also these babies should follow up properly to detect complication/s at earliest, and take “early intervention’’ steps.Asian Journal of Medical Sciences Vol.7(5) 2016 61-69


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Stefania Longo ◽  
Camilla Caporali ◽  
Camilla Pisoni ◽  
Alessandro Borghesi ◽  
Gianfranco Perotti ◽  
...  

AbstractPreterm very low birth weight infants (VLBWi) are known to be at greater risk of adverse neurodevelopmental outcome. Identifying early factors associated with outcome is essential in order to refer patients for early intervention. Few studies have investigated neurodevelopmental outcome in Italian VLBWi. The aim of our longitudinal study is to describe neurodevelopmental outcome at 24 months of corrected age in an eleven-year cohort of 502 Italian preterm VLBWi and to identify associations with outcome. At 24 months, Griffiths’ Mental Developmental Scales were administered. Neurodevelopmental outcome was classified as: normal, minor sequelae (minor neurological signs, General Quotient between 76 and 87), major sequelae (cerebral palsy; General Quotient ≤ 75; severe sensory impairment). 75.3% showed a normal outcome, 13.9% minor sequelae and 10.8% major sequelae (3.8% cerebral palsy). Male gender, bronchopulmonary dysplasia, abnormal neonatal neurological assessment and severe brain ultrasound abnormalities were independently associated with poor outcome on multivariate ordered logistic regression. Rates of major sequelae are in line with international studies, as is the prevalence of developmental delay over cerebral palsy. Analysis of perinatal complications and the combination of close cUS monitoring and neurological assessment are still essential for early identification of infants with adverse outcome.


Author(s):  
Kousiki Patra ◽  
Michelle M. Greene ◽  
Grace Tobin ◽  
Gina Casini ◽  
Anita L. Esquerra-Zwiers ◽  
...  

Author(s):  
K. Famra ◽  
P. Barta ◽  
A. Aggarwal ◽  
B.D. Banerjee

OBJECTIVES: Neonatal seizures are significant cause of neonatal mortality and morbidity. Current study was planned to study prevalence of adverse outcomes in neonatal seizures and identify its predictors. METHODS: This observational descriptive study was carried out on 220 neonates with seizures. Neonates who succumbed to illness/ death before investigations, or whose maternal records were incomplete were excluded. Blood sugar, serum calcium, serum electrolytes, and USG skull were done in all patients. CT scan, MRI and inborn errors of metabolism profile were done as and when indicated. Adverse outcomes were defined as death, phenobarbitone non responders, or abnormal examination at discharge. Antenatal, perinatal and neonatal predictors of adverse outcomes in neonatal seizures were evaluated. RESULTS: Out of 220 neonates with seizures 76(34.5%) had adverse outcomes. Very low birth weight babies (≤1500 gm) [OR 1.27(CI 0.57–2.84)], microcephaly [OR 5.93 (CI 0.55–64.41)], Apgar score≤3 at 5 minutes [OR 11.28(CI 14.18–30.45)], seizure onset within 24 hours [OR 5.99(CI 12.43–14.78)], meningitis [OR 2.63(CI 0.08–6.39)], septicemia [OR1.22(CI 0.45–3.31)] and abnormal cranial USG [OR 7.95(CI 12.61–24.22)] were significant predictors of adverse outcomes in neonates with seizures. CONCLUSION: Prematurity, very low birth weight, birth asphyxia, meningitis, septicemia and abnormal USG could predict adverse outcomes in neonatal seizures. Improved antenatal and neonatal clinical practices may help reduce adverse outcomes in these patients.


2018 ◽  
Vol 5 (2) ◽  
pp. 508 ◽  
Author(s):  
Prathiba N. Doddabasappa ◽  
N. S. Mahantshetti ◽  
Mahesh Kamate ◽  
Adarsh E.

Background: Low birth weight (LBW) is one of the risk factor for neurodevelopmental delay. The present study was undertaken to assess the role of the Kangaroo Mother Care (KMC) in the neurodevelopmental outcome of low birth weight babies. Methods: The present study was undertaken at Department of Paediatrics, Jawarharlal Medical college, Belgaum during the period from January 2009 to October 2010. The study includes 80 stable LBW babies were randomized into 40 in the KMC group and 40 in convention method of care group. 36 babies in the KMC group and 33 babies in the CMC group completed the study. The Neurodevelopmental outcome was assessed by the Amiel Tison test at three, six, nine and twelfth months of age. This was compared with BSID test, at one year.Results: The neurosensory examination and passive muscle tone (PMT) were found to be abnormal. Majority of the babies in both groups has a normal neurosensory and PMT development at one year. Statistically significant to muscle tone deficit was observed in the CMC babies at six months and nine months (p = 0.005 and p = 0.013). With respect to BSID, 16 and 29 KMC babies had a normal Psychomotor Development Index (PDI) and Motor Development Index (MDI) scores when compared to 8 and 18 CMC babies (p = 0.003 and p = 0.057 respectively). Number of babies with significant delay was observed to be higher in the CMC group being 11 versus 1 for PDI scores and 4 versus 1 for MDI scores.Conclusions: The present study shows that KMC has a beneficial effect on the neurodevelopmental outcome of low birth weight babies and BSID II is a better test to detect the psychomotor and mental developmental delay when compared to the Amiel Tison test.


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