scholarly journals Study on Serum Magnesium Levels in Acute Myocardial Infarction

2021 ◽  
Vol 09 (12) ◽  
Author(s):  
Dr Ganta Aneesha ◽  
2013 ◽  
Vol 3 (2) ◽  
pp. 50-56
Author(s):  
MBK Choudhury ◽  
MM Hossain ◽  
M Akhtaruzzaman ◽  
MM Jamal Uddin ◽  
MS Rahman ◽  
...  

Magnesium (Mg) and potassium (K) are the major intracellular cations whose presence in the serum are low, but minor changes of those may show a remarkable change in the various body functions specially in the heart. The study was designed to find out the correlation between serum Mg and K in acute myocardial infarction (AMI), chronic ischemic heart disease (CIHD) and normal healthy volunteers. It was carried out over a period of 18 months in the Department of Biochemistry, Bangabandhu Sheikh Mujib Medical University (BSMMU) in collaboration with Department of Cardiology, Sir Salimullah Medical College & Mitford Hospital (SSMC & MH) and Atomic Energy Center, Dhaka. A total of 101 subjects were included in which 32 subjects were AMI, 34 CIHD and 35 normal healthy volunteers. Serum glucose and serum creatinine were estimated to exclude diabetes and renal dystrophies. Estimation of serum CK-MB and ECG tracing were done as diagnostic tools of AMI and to categories the subjects into various groups. Serum Mg was estimated by Atomic absorption spectrophotometer and serum K by Ion sensitive electrode. The present study shows that there is a strong positive correlation of serum Mg and K in AMI, CIHD and healthy control subjects (r = 0.566, p<0.01 level). So it is suggested to estimate and supplement both Mg and K in IHD patients for their better management. DOI: http://dx.doi.org/10.3329/bjmb.v3i2.13812 Bangladesh J Med Biochem 2010; 3(2): 50-56


2012 ◽  
Vol 17 (1) ◽  
pp. 33-36
Author(s):  
MBK Choudhury ◽  
MS Rahman ◽  
MM Hassan ◽  
R Begum ◽  
N Hoque ◽  
...  

The comparative study has been designed to estimate serum magnesium (Mg) and potassium (K) in patients with acute myocardial infarction (AMI) and chronic ischemic heart disease (CIHD). A total 61 subjects were selected and were divided as group-I (30 subjects of AMI) and group-II (31 subjects of CIHD). Laboratory investigations were done for estimation of serum glucose and serum creatinine to exclude the diabetes mellitus and renal disease. Serum Mg was estimated by atomic absorption spectrophotometer and serum K by ion selective electrode. This study showed that Mg and K level in serum is significantly lower in patients with AMI than that of CIHD subjects. Findings of the study suggested that significantly reduced serum level of Mg and K persists in AMI than those of CIHD, which may be the cause of further cardiac complications. So it may be recommended for estimation and supplementation of Mg and K in both the cases of AMI and CIHD patients for better management. DOI: http://dx.doi.org/10.3329/jdnmch.v17i1.12190 J. Dhaka National Med. Coll. Hos. 2011; 17 (01): 33-36


2018 ◽  
Vol 21 (02) ◽  
pp. 258-263
Author(s):  
Mukhtiar Hussain Jaffery ◽  
Khalida Shaikh ◽  
Ghulam Hussain Baloch ◽  
Syed Zulfiquar Ali Shah

Objective: This descriptive case series study evaluates the frequency ofhypomagnesemia in patients with acute myocardial infarction. Patients and methods: Thismultidisciplinary conducted at Liaquat University Hospital Hyderabad and a private hospitalHyderabad from May 2010 to October 2010. All patients diagnosed as acute myocardialinfarction were further evaluated for type of myocardial infarction and serum magnesium level.Results: Out of 100 diabetic patients, 77 were males and 23 patients were females. The meanage and standard deviation of patients of male and female was 54.78 ± 8.82 (SD) and 53.64 ±10.82 (SD), respectively. The mean ± SD for serum magnesium in overall subjects was 1.24±0.48. Regarding the type of AMI inferior wall in 22 (29%), lateral wall in 17 (22%), anteroseptal in12 (16%), anterolateral -V1 in 07(09%), right ventricular in 10 (13%) and posterior wall in 07 (09%).The mean duration of acute MI in male and female population was 8.71±6.73 hours and17.70±14.57 hours (p<0.01) where as the mean duration of acute MI in hypomagnesemic andnormomagnesemic patient was 5.16±2.49 hours and 26.60±8.27 (p = 0.02) respectively. Themean serum magnesium level in male as well as female population was 1.32 ±0.21 mg/dl and1.46± 0.53 mg/dl p = 0.05, respectively. Regarding the hypomagnesemia in male and femalepopulation was 34(75.6%) and 16(53.3%) p=0.04, respectively. The hypomagnesemia was morepredominant in inferior 18(36.0%) and lateral 16 (32.0%) wall MI. Conclusions: Thehypomagnesemia was observed in patients with acute myocardial infarction with statisticalsignificance


Author(s):  
M. Poorna Chandran ◽  
J. Kumanan

Background: Magnesium has been implicated in the pathogenesis of acute myocardial infarction and its complication like arrhythmia. Magnesium improves myocardial metabolism, inhibits calcium accumulation and myocardial cell death. Objective was to know the relationship between the serum magnesium levels and arrhythmias in patients with acute myocardial infarction.Methods: It was a hospital based cross sectional study. By using simple random method, 50 cases of acute myocardial infarction, admitted in a tertiary care hospital in Chennai for the period of two years. Simple descriptive analysis was done to find out frequencies and percentages. For the test of significance the Chi-square test was used.Results: In our study group of 50 subjects, 28 (56%) of patients developed arrhythmias and 22 (44%) of patients recovered without any complications. Variation in type of Myocardial Infarction among our study 50 patients were 22 (44%) had anterior wall MI, 21 (42%) patients had Inferior wall MI and 7 (14%) patients had anteroseptal MI. The mean Mg level for the arrhythmias patients for the day 1 and day 5 were 1.70±0.16 and 1.76±0.51 and 2.10±0.19 and for patients without arrhythmias 2.26±0.20. There is a significant difference in the magnesium levels in patients with arrhythmias and without arrhythmias.Conclusions: In acute myocardial infarct ion, patients with low magnesium levels are more prone to get arrhythmias. So magnesium treatment can be considered in patients of acute myocardial infarct ion with low magnesium levels.


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