Randomized, open-label, controlled, comparative study on switching HIV-infected patients with their antiretroviral therapy experience to a DTG and 3TC regimen: 96-weeks results

Author(s):  
Kanestri V.G. Kanestri ◽  
Kravchenko A.V. Kravchenko ◽  
Pokrovskaya A.V. Pokrovskaya ◽  
Kulabukhova E.I. Kulabukhova ◽  
Kuimova U.A. Kuimova ◽  
...  
2011 ◽  
Vol 54 (6) ◽  
pp. 729-735 ◽  
Author(s):  
Nicolas Munoz-Bongrand ◽  
Tigran Poghosyan ◽  
Sarah Zohar ◽  
Laurence Gerard ◽  
Mircea Chirica ◽  
...  

2020 ◽  
Vol 12 (1) ◽  
pp. 59-68
Author(s):  
Alex Souto Maior ◽  
Marcio Tannure ◽  
Fábio Eiras ◽  
Arthur de Sá Ferreira

SummaryStudy aim: This study compared the effects of intermittent negative pressure therapy (INPT) vs. active recovery therapy (ART) on post-match physiological parameters such as serum CK level and skin temperature of the lower limbs in elite soccer players.Material and methods: Twenty healthy male professional soccer players from a Brazilian first division soccer club were enrolled in this randomized, parallel arm, open label, comparative study. After participating in 2 soccer matches, they were randomly assigned to two groups (n = 10) to receive a 30-min session of INPT (intermittent exchange of hypobaric pressure range 33 to 51 mmHg) or ART (self-myofascial release, mobility and stability exercises, and cycle ergometer exercise). The intervention was conducted after a match with assessments immediately before and after the intervention and again 24 h after the intervention.Results: A significant interaction effect (F2,36 = 4.503, p = 0.018, η2 = 0.130) was observed, indicating that the decrease of CK from pre-intervention to 24 h post-intervention was greater in the INPT than in the ART group. Lower limb skin temperature was significantly lower after INPT than after ART (p < 0.003).Conclusions: Serum CK level and skin temperature of lower limbs showed better recovery up to 24 h after the intervention with INPT in elite soccer players.


Author(s):  
VASUNDHARA BHOPLE ◽  
DEEPAK BHOSLE

Objective: The objective of this study was to compare the effect of chitosan, lifestyle modification, and combination of chitosan and lifestyle modification on body mass index (BMI) in obese patients. Methods: A prospective, randomized, open-label comparative study conducted for the period of 24 weeks. The study population was enrolled in three groups (chitosan 500 mg BD, lifestyle modification, and chitosan 500 mg BD and lifestyle modification). Data were analyzed using “t”-test and ANOVA. Results: There is a reduction in BMI in all the three groups. However, when we combined chitosan and lifestyle modification, there is pronounced reduction in BMI, which is statistically significant (p<0.0001). Conclusions: Chitosan and lifestyle modification have more pronounced effect on reduction on BMI as compared to monotherapy alone.


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