scholarly journals Repressor element-1 silencing transcription factor regulates glutamate receptors and immediate early genes to affect synaptic plasticity

Aging ◽  
2021 ◽  
Author(s):  
Chenhaoyi Xu ◽  
Min Zhang ◽  
Lu Zu ◽  
Pei Zhang ◽  
Letao Sun ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Synaptic Plasticity ◽  
Glutamate Receptors ◽  
Immediate Early Genes ◽  
Immediate Early ◽  
Early Genes ◽  
Repressor Element

scholarly journals LINC00473 as an Immediate Early Gene under the Control of the EGR1 Transcription Factor

2020 ◽  
Vol 6 (4) ◽  
pp. 46
Author(s):  
Vincenza Aliperti ◽  
Emilia Vitale ◽  
Francesco Aniello ◽  
Aldo Donizetti
Keyword(s):  
Gene Expression ◽  
Transcription Factor ◽  
Immediate Early Genes ◽  
Immediate Early Gene ◽  
Early Gene ◽  
Immediate Early ◽  
Secondary Response ◽  
Early Genes ◽  
Regulatory Cascade ◽  
Non Coding Rnas

Immediate early genes play an essential role in cellular responses to different stimuli. Many of them are transcription factors that regulate the secondary response gene expression. Non-coding RNAs may also be involved in this regulatory cascade. In fact, they are emerging as key actors of gene expression regulation, and evidence suggests that their dysregulation may underly pathological states. We previously took a snapshot of both coding and long non-coding RNAs differentially expressed in neuronal cells after brain-derived neurotrophic factor stimulation. Among these, the transcription factor EGR1 (a well-known immediate early gene) and LINC00473 (a primate-specific long non-coding RNA) that has emerged as an interesting RNA candidate involved in neuronal function and in cancer. In this work, we demonstrated that LINC00473 gene expression kinetics resembled that of immediate early genes in SH-SY5Y and HEK293T cells under different cell stimulation conditions. Moreover, we showed that the expression of LINC00473 is under the control of the transcription factor EGR1, providing evidence for an interesting functional relationship in neuron function.

Measles virus enhances the expression of cellular immediate-early genes and DNA-binding of transcription factor AP-1 in lung epithelial A549 cells

2002 ◽  
Vol 147 (9) ◽  
pp. 1721-1732 ◽  
Author(s):  
E. Helin ◽  
S. Matikainen ◽  
I. Julkunen ◽  
J. Heino ◽  
T. Hyypiä ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Dna Binding ◽  
Measles Virus ◽  
A549 Cells ◽  
Immediate Early Genes ◽  
Immediate Early ◽  
Early Genes ◽  
Lung Epithelial

Angiotensin II Type 1 Receptor Blockade Inhibits the Expression of Immediate-Early Genes and Fibronectin in Rat Injured Artery

Circulation ◽  
1995 ◽  
Vol 92 (1) ◽  
pp. 88-95 ◽  
Author(s):  
Shokei Kim ◽  
Masaki Kawamura ◽  
Hideki Wanibuchi ◽  
Kensuke Ohta ◽  
Akinori Hamaguchi ◽  
...  
Keyword(s):  
Angiotensin Ii ◽  
Immediate Early Genes ◽  
Immediate Early ◽  
Receptor Blockade ◽  
Early Genes ◽  
Injured Artery
Sign in / Sign up

Export Citation Format

Share Document