scholarly journals Berry anthocyanidins inhibit intestinal polyps and colon tumors by modulation of Src, EGFR and the colon inflammatory environment

Oncoscience ◽  
2021 ◽  
Vol 8 ◽  
pp. 120-133
Author(s):  
Ashley M. Mudd ◽  
Tao Gu ◽  
Radha Munagala ◽  
Jeyaprakash Jeyabalan ◽  
Mostafa Fraig ◽  
...  
Keyword(s):  
Colon Tumors ◽  
Intestinal Polyps

Signal transduction therapy of colon tumors with multiple target kinase inhibitors

2009 ◽  
Vol 47 (05) ◽  
Author(s):  
G Kéri ◽  
L Őrfi ◽  
Z Greff ◽  
Z Varga ◽  
B Szokol ◽  
...  
Keyword(s):  
Signal Transduction ◽  
Kinase Inhibitors ◽  
Multiple Target ◽  
Colon Tumors ◽  
Signal Transduction Therapy

Perbandingan CART dan Random Forest untuk Deteksi Kanker berbasis Klasifikasi Data Microarray

2020 ◽  
Vol 4 (5) ◽  
pp. 805-812
Author(s):  
Riska Chairunisa ◽  
Adiwijaya ◽  
Widi Astuti
Keyword(s):  
Breast Cancer ◽  
Lung Cancer ◽  
Ovarian Cancer ◽  
Random Forest ◽  
Classification And Regression Tree ◽  
Classification Method ◽  
Discrete Wavelet ◽  
Prostate Tumors ◽  
Cancer Data ◽  
Colon Tumors

Cancer is one of the deadliest diseases in the world with a mortality rate of 57,3% in 2018 in Asia. Therefore, early diagnosis is needed to avoid an increase in mortality caused by cancer. As machine learning develops, cancer gene data can be processed using microarrays for early detection of cancer outbreaks. But the problem that microarray has is the number of attributes that are so numerous that it is necessary to do dimensional reduction. To overcome these problems, this study used dimensions reduction Discrete Wavelet Transform (DWT) with Classification and Regression Tree (CART) and Random Forest (RF) as classification method. The purpose of using these two classification methods is to find out which classification method produces the best performance when combined with the DWT dimension reduction. This research use five microarray data, namely Colon Tumors, Breast Cancer, Lung Cancer, Prostate Tumors and Ovarian Cancer from Kent-Ridge Biomedical Dataset. The best accuracy obtained in this study for breast cancer data were 76,92% with CART-DWT, Colon Tumors 90,1% with RF-DWT, lung cancer 100% with RF-DWT, prostate tumors 95,49% with RF-DWT, and ovarian cancer 100% with RF-DWT. From these results it can be concluded that RF-DWT is better than CART-DWT.  

The number of regulatory Foxp3+ T-cells in different stages of malignant transformation of large intestinal polyps

2016 ◽  
Vol 61 (2) ◽  
pp. 306-310 ◽  
Author(s):  
Mateusz Rubinkiewicz ◽  
Marcin Migaczewski ◽  
Jerzy Hankus ◽  
Marcin Dembiński ◽  
Michał Pędziwiatr ◽  
...  
Keyword(s):  
T Cells ◽  
Malignant Transformation ◽  
Intestinal Polyps

Induction of colon tumors by a single oral dose of 1,2-dimethylhydrazine

1980 ◽  
Vol 11 (1) ◽  
pp. 75-79 ◽  
Author(s):  
Carol M. Schiller ◽  
Winifred H. Curley ◽  
Ernest E. McConnell
Keyword(s):  
Oral Dose ◽  
Single Oral Dose ◽  
Colon Tumors

Modulation of 5-fluorouracil host-toxicity and chemotherapeutic efficacy against human colon tumors by 5-(Phenylthio)acyclouridine, a uridine phosphorylase inhibitor

2006 ◽  
Vol 58 (5) ◽  
pp. 692-698 ◽  
Author(s):  
Omar N. Al Safarjalani ◽  
Reem Rais ◽  
Junxing Shi ◽  
Raymond F. Schinazi ◽  
Fardos N. M. Naguib ◽  
...  
Keyword(s):  
Human Colon ◽  
Uridine Phosphorylase ◽  
Colon Tumors ◽  
Chemotherapeutic Efficacy ◽  
Uridine Phosphorylase Inhibitor

scholarly journals Chemoprevention of mouse lung and colon tumors by suberoylanilide hydroxamic acid and atorvastatin

2012 ◽  
Vol 131 (6) ◽  
pp. 1277-1286 ◽  
Author(s):  
Michael A. Pereira ◽  
Blake M. Warner ◽  
Thomas J. Knobloch ◽  
Christopher M. Weghorst ◽  
Ronald A. Lubet ◽  
...  
Keyword(s):  
Hydroxamic Acid ◽  
Mouse Lung ◽  
Suberoylanilide Hydroxamic Acid ◽  
Colon Tumors

scholarly journals Overexpression of low-density lipoprotein receptor and lipid accumulation in intestinal polyps in Min mice

2009 ◽  
Vol 125 (11) ◽  
pp. 2505-2510 ◽  
Author(s):  
Michihiro Mutoh ◽  
Masami Komiya ◽  
Naoya Teraoka ◽  
Toshiya Ueno ◽  
Mami Takahashi ◽  
...  
Keyword(s):  
Lipid Accumulation ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Low Density ◽  
Lipoprotein Receptor ◽  
Low Density Lipoprotein Receptor ◽  
Intestinal Polyps ◽  
Density Lipoprotein Receptor

Endoscopic and Histopathological Characteristics of Polypoid and Non-Polypoid Colorectal Lesions in Patients of a Social Security Hospital of Lambayeque, Peru

2021 ◽  
Vol 15 (8) ◽  
pp. 2284-2287
Author(s):  
Jhon Franksis Munoz Chumpen ◽  
Mario J. Valladares-garrido
Keyword(s):  
Social Security ◽  
Transverse Colon ◽  
Cross Sectional Study ◽  
Hyperplastic Polyps ◽  
Sectional Study ◽  
Cross Sectional ◽  
Size And Shape ◽  
Intestinal Polyps ◽  
Paris Classification

Objective: To describe the endoscopic and histopathological characteristics of polypoid and non-polypoid colorectal lesions at the Luis Heysen Inchaustegui hospital, Peru, 2017-2018. Materials and methods: Descriptive-analytical cross-sectional study. We study epidemiological, endoscopic and histopathological variables. location, Size and shape of the lesions taking into account the Paris classification. Results: Endoscopically, of a total of 81 colorectal lesions, the majority were non-polypoid (71.6%). Lesions smaller than 10mm represented 90.1% in non-polypoid lesions and 56.5 % in polypoid lesions. Histopathologically, non-adenomatous lesions predominated (53.0%). Conclusions: The most frequent lesions were non-polypoid, the main location being the rectum; while in polypoid lesions, the transverse colon. Regarding size, lesions smaller than 10mm predominated in both non-polypoid and polypoid lesions. Histopathologically, the most frequent were non-adenomatous lesions (hyperplastic polyps); for its part, the predominant adenoma subtype was tubular. Keywords: Adenomas; Polyps; Intestinal Polyps; Colon (source: DeCS BIREME).

scholarly journals Bone and dental abnormalities as first signs of familial Gardner’s syndrome in a Chinese family: a literature review and a case report

2018 ◽  
Vol 34 ◽  
pp. 20-25 ◽  
Author(s):  
Dan Yu ◽  
Benjamin NG CW ◽  
Huiyong Zhu ◽  
Jianhua Liu ◽  
Yi Lin
Keyword(s):  
Gastrointestinal Symptoms ◽  
Soft Tissue Tumors ◽  
Chinese Family ◽  
Gardner's Syndrome ◽  
Dental Anomalies ◽  
Gardner’S Syndrome ◽  
Intestinal Polyps ◽  
Family Pedigree ◽  
Caucasian Race ◽  
Dominant Disease

Gardner’s syndrome (GS) is an autosomal dominant disease characterized by the presence of familial adenomatous polyposis (FAP) as well as extraintestinal manifestations such as osteomas, dental anomalies, epidermoid cysts and ocular abnormalities. These intestinal polyps carry a 100% risk of malignant change, so early diagnosis is crucial. As craniofacial osteomas and dental anomalies of GS usually precede gastrointestinal symptoms, otolaryngologists, oral surgeons and dentists play an important role in the diagnosis of GS. GS is extensively reported in literature in the Caucasian race but not in the Mongoloid race. We report a case of a 22-year-old patient with a manifestation of three features of GS - multiple osteomas, soft tissue tumors and dental anomalies in the craniofacial region, with no intestinal polyps at the time of reporting. A family pedigree with our patient as the proband was constructed and revealed 3 consecutive generations in his lineage with GS.

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