scholarly journals Hypertension and dyslipidemia. Parallel risk factor control: role of fixed combination

2021 ◽  
Vol 27 (3) ◽  
pp. 376-383
Author(s):  
A. O. Konradi ◽  
A. S. Alieva
Keyword(s):  
Blood Pressure ◽  
Patient Adherence ◽  
Effective Control ◽  
Adherence To Treatment ◽  
Primary And Secondary Prevention ◽  
Risk Factor Control ◽  
Promising Strategy ◽  
Cardiovascular Continuum

The combined effect of dyslipidemia and high blood pressure largely contributes to the development and progression of cardiovascular diseases, and therefore the control of these risk factors should be a priority strategy both within primary and secondary prevention. A concept of a polypill, which provides effective control of both blood pressure and lipid profile, is a promising strategy. It allows of controlling several factors of the cardiovascular continuum, and contributes to a higher patient adherence to treatment. Therefore, the wider implementation of a polypill strategy will improve patients’ prognosis and quality of life.

scholarly journals Role of adherence in prevention of hypertension

2019 ◽  
Vol 2 (30) ◽  
pp. 28-32
Author(s):  
Yu. N. Fedulaev ◽  
N. D. Karseladze ◽  
F. A. Evdokimov ◽  
A. Yu. Chuprakova ◽  
S. A. Sapozhnikov ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Blood Pressure ◽  
Patient Adherence ◽  
Health Centers ◽  
Adherence To Treatment ◽  
Multicenter Studies ◽  
Prevention Of Hypertension ◽  
Significant Disease

Arterial hypertension remains a socially significant disease. Multicenter studies indicate low patient adherence to treatment. This article discusses the factors that influence commitment. Using the potentials of health centers and prevention departments can increase patient commitment. The study on the regular use of antihypertensive therapy indicates an improvement in cognitive functions and the quality of life of patients against the background of achieving target blood pressure.

The role of acoustics in building clean urban and architectural environment

BUILDER ◽  
2020 ◽  
Vol 276 (7) ◽  
pp. 44-46
Author(s):  
Joanna Jabłońska
Keyword(s):  
Blood Pressure ◽  
Built Environment ◽  
Time Perspective ◽  
Well Being ◽  
Living Conditions ◽  
Internal Organs ◽  
Research Outcomes ◽  
Sound Environment

Built environment of polish cities, both external and internal is polluted not only with chemical and physical harmful particles, but also with a number of diversified, continuous sounds, which may in substantial way negatively affect psychological and physical well-being of humans. Moreover, in extreme situations sound may damage vital organs of organisms and at daily occasions negative exposure may cause a number of problems in a longer time perspective. Noise produced by traffic, loudness of school brakes, shouts and car-horns, humming of air condition devices and ducts, air traffic, plus many more, are exposing city users not only on shorter or longer hearing losses, but also on vibration of internal organs and raising of overall anxiety. At the same time, cities are also filled with positive sounds, which allow to lower the blood pressure, calm and relax residents, like: birds singing, leaves and rain humming, water floating, and so on. Hence, this article was devoted towards presentation of research outcomes on pursuit for ‘cleaner’ and higher quality of sound environment in everyday city, in order to create safer and more ergonomic permanent, day-to-day living conditions.

scholarly journals A Review of Nutritional Factors in Hypertension Management

2013 ◽  
Vol 2013 ◽  
pp. 1-12 ◽  
Author(s):  
Ha Nguyen ◽  
Olaide A. Odelola ◽  
Janani Rangaswami ◽  
Aman Amanullah
Keyword(s):  
Blood Pressure ◽  
Pressure Control ◽  
Current Evidence ◽  
Dietary Modification ◽  
Hypertension Management ◽  
Major Health Problem ◽  
Major Health ◽  
Nutritional Factors

Hypertension is a major health problem worldwide. Its attendant morbidity and mortality complications have a great impact on patient’s quality of life and survival. Optimizing blood pressure control has been shown to improve overall health outcomes. In addition to pharmacological therapies, nonpharmacological approach such as dietary modification plays an important role in controlling blood pressure. Many dietary components such as sodium, potassium, calcium, and magnesium have been studied substantially in the past decades. While some of these nutrients have clear evidence for their recommendation, some remain controversial and are still of ongoing study. Dietary modification is often discussed with patients and can provide a great benefit in blood pressure regulation. As such, reviewing the current evidence will be very useful in guiding patients and their physician and/or dietician in decision making. In this review article of nutritional factors in hypertension management, we aim to examine the role of nutritional factors individually and as components of whole dietary patterns.

scholarly journals Problems of pain and quality of life in rheumatoid arthritis: focus on baricitinib

2020 ◽  
Vol 58 (4) ◽  
pp. 420-427
Author(s):  
A. E. Karateev
Keyword(s):  
Rheumatoid Arthritis ◽  
Intracellular Signaling ◽  
Janus Kinase ◽  
Effective Control ◽  
Signal Transducers ◽  
Intracellular Signaling Pathway ◽  
Autoimmune Inflammation ◽  
Immune Mediated

Modern therapy for rheumatoid arthritis (RA) allows not only to reduce the activity of immune-mediated inflammation and slow down the progression of the disease, but also to quickly eliminate the main symptoms that cause the most concern to patients, such as pain, functional disorders, fatigue. This action has an inhibitor of Janus kinases 1/ 2 – baricitinib, which quickly reduces the activity of inflammation, provides remission in RA, and has a high analgesic effect. The review discusses the role of autoimmune inflammation and the intracellular signaling pathway JAK/STAT (Janus kinase/signal transducers and activators of transcription) in the pathogenesis of chronic pain in RA, the role of baricitinib for effective control of pain intensity and fatigue. 

scholarly journals Quality of tuberculosis care and its association with patient adherence to treatment in eight Ethiopian districts

2009 ◽  
Vol 24 (6) ◽  
pp. 457-466 ◽  
Author(s):  
M. M Mesfin ◽  
J. N Newell ◽  
J. D Walley ◽  
A. Gessessew ◽  
T. Tesfaye ◽  
...  
Keyword(s):  
Patient Adherence ◽  
Adherence To Treatment ◽  
Tuberculosis Care

scholarly journals The study of medication adherence in patients with arterial hypertension in the practice of a family doctor

2021 ◽  
pp. 76-82
Author(s):  
К. Vovk ◽  
O. Sokruto ◽  
A. Кratenko ◽  
R. Redkin ◽  
N. Orlovetska ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Blood Pressure ◽  
Medication Adherence ◽  
Arterial Hypertension ◽  
Initial Level ◽  
Patient Adherence ◽  
Family Doctor ◽  
The Body ◽  
Brain Vessels

The treatment of arterial hypertension (AH) is one of the most significant problems of modern internal medicine. Elevated blood pressure (BP) is a major risk factor for atherosclerosis, mainly coronary heart disease and damage tothe brain vessels. Medication adherence (MA) is a complex problem in patients with chronic cardiovascular diseases, especially AH.Aim. To study MA when treating patients with AH in a real Ukrainian out-patient practice for 8 weeks.Materials and methods. The sample of 274 patients with AH included men and women over 18 years old with the initial level of office systolic blood pressure (SBP) of 140-179 mm Hg and diastolic blood pressure (DBP) of 99-100 mm Hg against the background of the antihypertensive therapy or without it. Initially, BP was measured at the doctor’s office (office blood pressure) in all patients who were enrolled in the study; the body mass index (BMI), as well as risk factors were calculated, and the concomitant therapy was assessed. The quality of life was determined by a visual analog scale (VAS score). Patient adherence to the drug therapy was evaluated using the Morisky Medication Adherence Scale (MMAS).Results and discussion. To conduct the study according the MMAS test all patients were distributed in two groups with low MA (MMAS = 3 or 4, n = 181) or high MA (MMAS ≤ 2, n = 93) by the psychometric scale. The results of the MMAS test obtained were confirmed by the reliability parameter used in psychometrics (Cronbach’s Alpha ˃ 0.7). It was found at the end of the study that BP levels less than 140/90 mm Hg of 50.6 % of the Low MA group patients and 47.7 % of the High MA group patients were reached. A decrease in SBP < 140 mm Hg or a decrease in 20 mm Hg and more from the initial level, as well as a decrease in DBP < 90 mm Hg or 10 mm Hg and more was observed in 98.8% of patients in the Low MA group and in 98.4 % in the High MA group. After 8 weeks of observation, the quality of life significantly improved in both groups; however, in the Low MA group this improvement was more pronounced – more than 85 points instead of 82.8 by the VAS scores for the High MA group.Conclusions. The effectiveness of the AH treatment and achievement in the target BP level depend on the patient’s MA. Regular visits to the family doctor’s clinic mobilize patients, and are one of the factors that increase adherence to the treatment, along with pharmaceutical care.

scholarly journals Implantable cardioverter defibrillators in the prevention of sudden cardiac death

2017 ◽  
Vol 89 (12) ◽  
pp. 103-109
Author(s):  
L A Bockeria ◽  
N M Neminushchiy ◽  
S I Mikhaylichenko ◽  
S A Novichkov ◽  
E E Achkasov
Keyword(s):  
Sudden Cardiac Death ◽  
Secondary Prevention ◽  
Cardiac Death ◽  
Antiarrhythmic Drugs ◽  
Implantable Cardioverter Defibrillators ◽  
Primary And Secondary Prevention ◽  
Multicenter Studies ◽  
Cardioverter Defibrillators

The article highlights the role of implantable cardioverter defibrillators (ICDs) in the primary and secondary prevention of sudden cardiac death. It considers the results of multicenter studies comparing the efficacy of antiarrhythmic drugs and implantable devices in the primary and secondary prevention of sudden cardiac death, including that in patients with nonischemic cardiomyopathy and discusses quality of life in patients with ICDs.

scholarly journals Tactics features for managing out-patients with cardiovascular comorbidity in Krasnoyarsk city

2020 ◽  
pp. 63-69
Author(s):  
M.A. Khramchenko ◽  
◽  
A.D. Karpenkova ◽  
M.M. Petrova ◽  
D.S. Kaskaeva ◽  
...  
Keyword(s):  
Total Cholesterol ◽  
Clinical Guidelines ◽  
Total Cholesterol Level ◽  
Lipid Lowering ◽  
Lipid Lowering Therapy ◽  
Primary And Secondary Prevention ◽  
Cardiovascular Comorbidity ◽  
Cardiovascular Continuum

The aim of the research is to study the structure of cardiovascular continuum within comorbid pathology within outpatient clinic of Krasnoyarsk; to evaluate the quality of out-patients management in accordance with modern clinical guidelines. Material and methods. To conduct a single retrospective analysis, 1928 medical records of Krasnoyarsk cardiovascular out-patients were taken. All the patients consulted local therapists in 2018. Differences were statistically significant at p <0.05. Results. Comorbid pathology is observed in patients with CVD in 87% of cases, and its growth is noted with age. It was revealed that ischemic heart disease (CHD) and obesity are associated with type 2 diabetes mellitus (DM-2). When using antihypertensive therapy, 43.2% of patients achieved blood pressure (BP) values <140/80 mm Hg. In 46.8% of cases, patients who were prescribed statins had total cholesterol (TC) values <5.0 mmol / L. Only 18.5% of patients with DM-2, following lipid-lowering therapy had a total cholesterol level <4.5 mmol / L, that was also registered only in 15.9% of patients with chronic kidney disease (CKD). Heart rate (HR) <80 beats / min was observed in 75% of patients taking drugs of b-blocker group. Conclusion. Cardiovascular comorbidity among patients is widespread and its rates are evidenced to increase with age. Antihypertensive, lipid-lowering and antithrombotic therapy do not fully comply with current clinical guidelines. It is necessary to individualize the approach to patients with combined pathology; to provide comprehensive diagnosis, treatment, and to inform the population on primary and secondary prevention adequately

Effective strategies for prevention of cardiovascular complications in elderly patients with arterial hypertension and obesity (clinical example)

2020 ◽  
pp. 10-18
Author(s):  
A. P. Pereverzev ◽  
O. D. Ostroumova ◽  
E. V. Mironova
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Blood Pressure ◽  
Body Weight ◽  
Arterial Hypertension ◽  
Cognitive Training ◽  
Blood Pressure Reduction ◽  
Cardiovascular Complications ◽  
Effective Control

The frequency of arterial hypertension has a clear tendency to increase with age. The presence of obesity imposes additional difficulties on the choice of antihypertensive therapy regimen due to the variety of pathophysiological mechanisms of raising blood pressure in patients with a combination of hypertension and obesity. This article presents the clinical case of a 68-year-old patient with hypertension and obesity, discusses a comprehensive approach that includes diet, regular physical activity, cognitive training and pharmacotherapy with the fixed combination of amlodipine with telmisartan and the imidazoline receptor agonist moxonidine. The choice of this combination is due to the following reasons: the ultra-prolonged action of both drugs, which allows you to control blood pressure during the day, including in the morning, when there is the greatest number of cardiovascular events; organoprotective properties; improving carbohydrate metabolism; reducing the risk of diabetes; antiatherosclerotic properties. The choice of moxonidine is due to the need of effective control of blood pressure, reduction of the activity of the sympathetic nervous system, because hypersympathicotonia is one of the central pathogenetic mechanisms for raising blood pressure in patients with hypertension and obesity, and the decrease in resting heart rate less than 80 bpm (an independent risk factor for cardiovascular complications in hypertension). Dietary recommendations will help to reduce body weight and blood pressure, slow the progression of atherosclerosis, prevent the development of cardiovascular catastrophes, and improve the quality of life. The aim of physical activity is reducing body weight, improve cognitive functions and reduce cardiovascular risks. Cognitive training will help improve cognitive function and, consequently, increase patient adherence to treatment. After six weeks of complex treatment, the patient noted the achievement of the target blood pressure, weight loss, improved mood, increased exercise tolerance, improved quality of life, as well as a decrease in proteinuria, which completely disappeared after another three months of therapy.

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