ETIOLOGICAL SPECTRUM OF CAUSATIVE PATHOGENS AND FEATURES OF THE COURSE OF PYELONEPHRITIS IN CHILDREN FROM DIFFERENT REGIONS OF DAGESTAN

The data on the analysis of the etiological structure of pyelonephritis pathogens in 303 children, from different regions of the Republic of Dagestan, is presented in dependence on the form of the disease, leading uropathogen, and inflammatory activity. Pyelonephritis with the prevalence of the chronic course was established to take the first place in the structure of urinary system infections in children of the Republic of Dagestan. At the same time, children suffering from secondary pyelonephritis caused by cocci showed more severity of pain and intoxication syndromes, which requires an optimal correction. Knowledge of the modern structure of pyelonephritis pathogens in each of the examined groups allows a timely and differentiated approach to the appointment of timely antibiotic therapy.

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Development of key quality indicators for appropriate antibiotic use in the Republic of Korea: results of a modified Delphi survey

Antimicrobial Resistance and Infection Control ◽

10.1186/s13756-021-00913-y ◽

2021 ◽

Vol 10 (1) ◽

Author(s):

Bongyoung Kim ◽

◽

Myung Jin Lee ◽

Se Yoon Park ◽

Song Mi Moon ◽

...

Keyword(s):

Antibiotic Therapy ◽

Quality Indicators ◽

Antibiotic Stewardship ◽

Antibiotic Use ◽

Republic Of Korea ◽

Cochrane Library ◽

Surgical Prophylaxis ◽

Modified Delphi ◽

Stewardship Program ◽

The Republic

Abstract Background An effective antibiotic stewardship program relies on the measurement of appropriate antibiotic use, on which there is a lack of consensus. We aimed to develop a set of key quality indicators (QIs) for nationwide point surveillance in the Republic of Korea. Methods A systematic literature search of PubMed, EMBASE, and Cochrane Library (publications until 20th November 2019) was conducted. Potential key QIs were retrieved from the search and then evaluated by a multidisciplinary expert panel using a RAND-modified Delphi procedure comprising two online surveys and a face-to-face meeting. Results The 23 potential key QIs identified from 21 studies were submitted to 25 multidisciplinary expert panels, and 17 key QIs were retained, with a high level of agreement (13 QIs for inpatients, 7 for outpatients, and 3 for surgical prophylaxis). After adding up the importance score and applicability, six key QIs [6 QIs (Q 1–6) for inpatients and 3 (Q 1, 2, and 5) for outpatients] were selected. (1) Prescribe empirical antibiotic therapy according to guideline, (2) change empirical antibiotics to pathogen-directed therapy, (3) obtain culture samples from suspected infection sites, (4) obtain two blood cultures, (5) adapt antibiotic dosage to renal function, and (6) document antibiotic plan. In surgical prophylaxis, the QIs to prescribe antibiotics according to the guideline and initiate antibiotic therapy 1 h before incision were selected. Conclusions We identified key QIs to measure the appropriateness of antibiotic therapy to identify targets for improvement and to evaluate the effects of antibiotic stewardship intervention.

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Optimization of Therapeutic Measurements in Rotavirus Infection in Infants with Perinatal Exposure to HIV

Archive of Clinical Medicine ◽

10.21802/acm.2016.2.13 ◽

2016 ◽

Vol 22 (2) ◽

pp. 2016213

Author(s):

Hryhoriy Trotskyy

Keyword(s):

Serum Level ◽

Antibiotic Therapy ◽

Antimicrobial Therapy ◽

Clinical Course ◽

Inflammatory Activity ◽

Perinatal Exposure ◽

Procalcitonin Level ◽

Rotavirus Infection ◽

Basic Treatment

The features of the clinical course of rotavirus infection in infants with perinatal exposure to HIV were studied. Serum level of procalcitonin as a marker of inflammatory activity and the need for antimicrobial therapy was determined. The efficiency of the proposed additions to basic treatment (low-lactose mixture for two months, antibiotic therapy in case of elevated procalcitonin level) was demonstrated.

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To the question of the fight against lupus in the Republic of Tatarstan

Kazan medical journal ◽

10.17816/kazmj58967 ◽

1930 ◽

Vol 26 (12) ◽

pp. 1224-1234

Author(s):

P. M. Batunin ◽

N. N. Chumakov

Keyword(s):

Social Significance ◽

Lupus Vulgaris ◽

The Social ◽

The Republic ◽

Chronic Course

Lupus (lupus vulgaris) is currently attracting the attention of dermatologists for many reasons, of which it is necessary to note the social and social significance of the issue, the frequency of the lesion and its consequences, as well as the extremely chronic course of the disease, the persistence and ingratitude of this suffering in relation to therapy.

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Subcutaneous dirofilariasis of maxillofacial localization - a rare clinical case

Kazan medical journal ◽

10.17816/kmj2018-829 ◽

2018 ◽

Vol 99 (5) ◽

pp. 829-832

Author(s):

S S Ksembaev ◽

O A Ivanov ◽

O E Torgashova ◽

A R Khamitova

Keyword(s):

Incubation Period ◽

Clinical Case ◽

Disease Development ◽

Sand Flies ◽

Humid Climate ◽

Maxillofacial Region ◽

History Of ◽

The Republic ◽

Insect Bites ◽

Chronic Course

Dirofilariasis is a tropical helminthosis caused by nematodes - filariae. The are characterized by long incubation period, slow disease development and its long chronic course. Dirofilariasis can be catched from humans and animals, it is transmitted through insect bites (mosquitoes, gadflies, sand flies, midges). Dirofilariasis is endemic to areas with warm and humid climate. In Russia, the disease is atypical, with the absence of mature nematodes and microfilariae in the tissues. This disease is not typical for the Republic of Tatarstan and only isolated cases of parasite localization in the eyeball were previously recorded. The article presents a rare clinical case of subcutaneous localization of nematode of dirofilaria in the maxillofacial region. The patient was diagnosed with tumor-like neoplasm of the maxillofacial region, on the removal of which a live incapsulated parasite was found. The patient had no history of visiting endemic countries.

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Development of key quality indicators for appropriate antibiotic use in the Republic of Korea: results of a modified Delphi survey

10.21203/rs.3.rs-111023/v2 ◽

2021 ◽

Author(s):

Bongyoung Kim ◽

Myung Jin Lee ◽

Se Yoon Park ◽

Song Mi Moon ◽

Kyoung-Ho Song ◽

...

Keyword(s):

Antibiotic Therapy ◽

Quality Indicators ◽

Antibiotic Stewardship ◽

Antibiotic Use ◽

Republic Of Korea ◽

Cochrane Library ◽

Surgical Prophylaxis ◽

Modified Delphi ◽

Stewardship Program ◽

The Republic

Abstract Background: An effective antibiotic stewardship program relies on the measurement of appropriate antibiotic use, on which there is a lack of consensus. We aimed to develop a set of key quality indicators (QIs) for nationwide point surveillance in the Republic of Korea.Methods: A systematic literature search of PubMed, EMBASE, and Cochrane Library (publications until 20th November 2019) was conducted. Potential key QIs were retrieved from the search and then evaluated by a multidisciplinary expert panel using a RAND-modified Delphi procedure comprising two online surveys and a face-to-face meeting. Results: The 23 potential key QIs identified from 21 studies were submitted to 25 multidisciplinary expert panels, and 17 key QIs were retained, with a high level of agreement (13 QIs for inpatients, 7 for outpatients, and 3 for surgical prophylaxis). After adding up the importance score and applicability, six key QIs [6 QIs (Q 1–6) for inpatients and 3 (Q 1, 2, and 5) for outpatients] were selected. (1) Prescribe empirical antibiotic therapy according to guideline, (2) change empirical antibiotics to pathogen-directed therapy, (3) obtain culture samples from suspected infection sites, (4) obtain two blood cultures, (5) adapt antibiotic dosage to renal function, and (6) document antibiotic plan. In surgical prophylaxis, the QIs to prescribe antibiotics according to the guideline and initiate antibiotic therapy 1 h before incision were selected.Conclusions: We identified key QIs to measure the appropriateness of antibiotic therapy to identify targets for improvement and to evaluate the effects of antibiotic stewardship intervention.

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Development of key quality indicators for appropriate antibiotic use in the Republic of Korea: results of a modified Delphi survey

10.21203/rs.3.rs-111023/v1 ◽

2020 ◽

Author(s):

Bongyoung Kim ◽

Myung Jin Kim ◽

Se Yoon Park ◽

Song Mi Moon ◽

Kyoung-Ho Song ◽

...

Keyword(s):

Antibiotic Therapy ◽

Quality Indicators ◽

Antibiotic Stewardship ◽

Antibiotic Use ◽

Republic Of Korea ◽

Cochrane Library ◽

Surgical Prophylaxis ◽

Modified Delphi ◽

Stewardship Program ◽

The Republic

Abstract Background: An effective antibiotic stewardship program relies on the measurement of appropriate antibiotic use, on which there is a lack of consensus. We aimed to develop a set of key quality indicators (QIs) for nationwide point surveillance in the Republic of Korea.Methods: A systematic literature search of PubMed, EMBASE, and Cochrane Library (publications until 20th November 2019) was conducted. Potential key QIs were retrieved from the search and then evaluated by a multidisciplinary expert panel using a RAND-modified Delphi procedure comprising two online surveys and a face-to-face meeting. Results: The 23 potential key QIs identified from 21 studies were submitted to 25 multidisciplinary expert panels, and 17 key QIs were retained, with a high level of agreement (13 QIs for inpatients, 7 for outpatients, and 3 for surgical prophylaxis). After adding up the importance score and applicability, six key QIs [6 QIs (Q 1–6) for inpatients and 3 (Q 1, 2, and 5) for outpatients] were selected: (1) prescribe empirical antibiotic therapy according to guideline, (2) change empirical antibiotics to pathogen-directed therapy, (3) obtain culture samples from suspected infection sites, (4) obtain two blood cultures, (5) adapt antibiotic dosage to renal function, and (6) document antibiotic plan. In surgical prophylaxis, the QI to prescribe antibiotics according to the guideline and initiate antibiotic therapy 1 h before incision was selected.Conclusions: We identified key QIs to measure the appropriateness of antibiotic therapy for the identification of targets for improvement and to evaluate effects of antibiotic stewardship intervention.

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Time and Latitude in South Africa

International Astronomical Union Colloquium ◽

10.1017/s0252921100026816 ◽

1972 ◽

Vol 1 ◽

pp. 27-38

Author(s):

J. Hers

Keyword(s):

South Africa ◽

Cape Town ◽

Astronomical Observations ◽

Royal Observatory ◽

The Republic ◽

Astronomical Determination ◽

Limited Accuracy ◽

Better Than

In South Africa the modern outlook towards time may be said to have started in 1948. Both the two major observatories, The Royal Observatory in Cape Town and the Union Observatory (now known as the Republic Observatory) in Johannesburg had, of course, been involved in the astronomical determination of time almost from their inception, and the Johannesburg Observatory has been responsible for the official time of South Africa since 1908. However the pendulum clocks then in use could not be relied on to provide an accuracy better than about 1/10 second, which was of the same order as that of the astronomical observations. It is doubtful if much use was made of even this limited accuracy outside the two observatories, and although there may – occasionally have been a demand for more accurate time, it was certainly not voiced.

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