scholarly journals Leveraging Implementation Science to Address Health Disparities in Genomic Medicine: Examples from the Field

2019 ◽  
Vol 29 (Suppl 1) ◽  
pp. 187-192 ◽  
Author(s):  
Megan C. Roberts ◽  
George A. Mensah ◽  
Muin J. Khoury
Keyword(s):  
Public Health ◽  
Implementation Science ◽  
Population Health ◽  
Public Health Practice ◽  
Genomic Medicine ◽  
Genomic Data ◽  
Health Impact ◽  
Cancer Syndrome ◽  
Public Health Agencies ◽  
Multi Stakeholder

The integration of genomic data into screen­ing, prevention, diagnosis, and treatment for clinical and public health practices has been slow and challenging. Implementa­tion science can be applied in tackling the barriers and challenges as well as exploring opportunities and best practices for integrat­ing genomic data into routine clinical and public health practice. In this article, we de­fine the state of disparities in genomic medi­cine and focus predominantly on late-stage research findings. We use case studies from genetic testing for cardiovascular diseases (familial hypercholesterolemia) and cancer (Lynch syndrome and hereditary breast and ovarian cancer syndrome) in high-risk populations to consider current disparities and related barriers in turning genomic advances into population health impact to advance health equity. Finally, we address how implementation science can address these translational barriers and we discuss the strategic importance of collaborative multi-stakeholder approaches that engage public health agencies, professional societ­ies, academic health and research centers, community clinics, and patients and their families to work collectively to improve population health and reduce or eliminate health inequities.Ethn Dis. 2019;29(Suppl 1):187-192; doi:10.18865/ed.29.S1.187.

scholarly journals Leveraging Implementation Science to Address Health Disparities in Genomic Medicine: Examples from the Field

2019 ◽  
Vol 29 (Suppl 1) ◽  
pp. 187-192
Author(s):  
Megan C. Roberts ◽  
George A. Mensah ◽  
Muin J. Khoury
Keyword(s):  
Public Health ◽  
Implementation Science ◽  
Population Health ◽  
Public Health Practice ◽  
Genomic Medicine ◽  
Genomic Data ◽  
Health Impact ◽  
Cancer Syndrome ◽  
Public Health Agencies ◽  
Multi Stakeholder

The integration of genomic data into screen­ing, prevention, diagnosis, and treatment for clinical and public health practices has been slow and challenging. Implementa­tion science can be applied in tackling the barriers and challenges as well as exploring opportunities and best practices for integrat­ing genomic data into routine clinical and public health practice. In this article, we de­fine the state of disparities in genomic medi­cine and focus predominantly on late-stage research findings. We use case studies from genetic testing for cardiovascular diseases (familial hypercholesterolemia) and cancer (Lynch syndrome and hereditary breast and ovarian cancer syndrome) in high-risk populations to consider current disparities and related barriers in turning genomic advances into population health impact to advance health equity. Finally, we address how implementation science can address these translational barriers and we discuss the strategic importance of collaborative multi-stakeholder approaches that engage public health agencies, professional societ­ies, academic health and research centers, community clinics, and patients and their families to work collectively to improve population health and reduce or eliminate health inequities.Ethn Dis. 2019;29(Suppl 1):187-192; doi:10.18865/ed.29.S1.187.

scholarly journals Public Health Challenges and Priorities for Kazakhstan

2012 ◽  
Vol 1 (1) ◽  
Author(s):  
Altyn Aringazina ◽  
Gabriel Gulis ◽  
John P. Allegrante
Keyword(s):  
Public Health ◽  
Health Care ◽  
Population Health ◽  
Public Health Practice ◽  
Health Impact ◽  
Health Concern ◽  
Health Care Reforms ◽  
New Public Health ◽  
Public Health Challenges ◽  
Health And Economic Development

The Republic of Kazakhstan is one of the largest and fastest growing post-Soviet economies in Central Asia. Despite recent improvements in health care in response to Kazakhstan 2030 and other state-mandated policy reforms, Kazakhstan still lags behind other members of the Commonwealth of Independent States of the European Region on key indicators of health and economic development. Although cardiovascular diseases are the leading cause of mortality among adults, HIV/AIDS, tuberculosis, and blood-borne infectious diseases are of increasing public health concern. Recent data suggest that while Kazakhstan has improved on some measures of population health status, many environmental and public health challenges remain. These include the need to improve public health infrastructure, address the social determinants of health, and implement better health impact assessments to inform health policies and public health practice. In addition, more than three decades after the Declaration of Alma-Ata, which was adopted at the International Conference on Primary Health Care convened in Kazakhstan in 1978, facilitating population-wide lifestyle and behavioral change to reduce risk factors for chronic and communicable diseases, as well as injuries, remains a high priority for emerging health care reforms and the new public health. This paper reviews the current public health challenges in Kazakhstan and describes five priorities for building public health capacity that are now being developed and undertaken at the Kazakhstan School of Public Health to strengthen population health in the country and the Central Asian Region.

E-Cigarettes: Implications for Health Promotion in the Asian Pacific Region

2018 ◽  
Vol 30 (4) ◽  
pp. 321-327 ◽  
Author(s):  
Jonine Jancey ◽  
Bruce Maycock ◽  
Kahlia McCausland ◽  
Peter Howat
Keyword(s):  
Public Health ◽  
Electronic Cigarettes ◽  
Public Health Practice ◽  
Health Impact ◽  
The United States ◽  
Pacific Region ◽  
New Device ◽  
Cautious Approach ◽  
Asian Pacific Region ◽  
Asian Pacific

Since their introduction to the United States in 2007, electronic cigarettes (e-cigarettes) use has grown exponentially. This rapid growth in e-cigarette use has been heralded by some as a potential important public health measure that could ultimately replace tobacco cigarettes, while others recommend a cautionary approach until there is clear evidence they will not become “new tobacco” bringing a possible myriad of other problems. E-cigarettes may have real benefits, however they do expose users and those nearby to organic compounds, solvents and particulate matter, with there being limited data relating to their health impact. It is unclear as to whether this relatively new device has the potential to exacerbate nicotine addictions, or play a part in reducing harm and smoking cessation. The fundamental requirement of public health practice is to do no harm and from the inconclusive evidence we have to date on e-cigarettes, it appears a cautious approach is warranted. This commentary reviews evidence that supports a cautious approach to e-cigarette availability in Australia and the Asian Pacific region.

Unpacking ‘the cloud’: a framework for implementing public health approaches to palliative care

2019 ◽  
Vol 35 (1) ◽  
pp. 160-170 ◽  
Author(s):  
Kathryn A Pfaff ◽  
Lisa Dolovich ◽  
Michelle Howard ◽  
Deborah Sattler ◽  
Merrick Zwarenstein ◽  
...  
Keyword(s):  
Public Health ◽  
Population Health ◽  
Systems Of Care ◽  
Health Impact ◽  
Population Based ◽  
Public Health Approach ◽  
Healthcare Needs ◽  
Health Level ◽  
The Social ◽  
Development Evaluation

Summary Designing and implementing population-based systems of care that address the social determinants of health, take action on multiple levels, and are guided by evidence-based principles is a pressing priority, and an international challenge. Aging persons are a priority demographic whose health needs span physical, psychosocial and existential care domains, increase in the last year of life, are often poorly coordinated and therefore remain unmet. Compassionate communities (CCs) are an example of a public health approach that fully addresses the holistic healthcare needs of those who are aging and nearing end of life. The sharing of resources, tools, and innovations among implementers of CCs is occurring globally. Although this can increase impact, it also generates complexity that can complicate robust evaluation. When initiating population health level projects, it is important to clearly define and organize concepts and processes that are proposed to influence the health outcomes. The Health Impact Change Model (HICM) was developed to unpack the complexities associated with the implementation and evaluation of a Canadian CC intervention. The HICM offers utility for citizens, leaders and decision-makers who are engaged in the implementation of population health level strategies or other social approaches to care, such as compassionate cities and age or dementia-friendly communities. The HICM’s concepts can be adapted to address a community’s healthcare context, needs, and goals for change. We share examples of how the model’s major concepts have been applied in the development, evaluation and spread of a complex CC approach.

scholarly journals Nutrient profiling for product reformulation: public health impact and benefits for the consumer

2017 ◽  
Vol 76 (3) ◽  
pp. 255-264 ◽  
Author(s):  
Undine Lehmann ◽  
Véronique Rheiner Charles ◽  
Antonis Vlassopoulos ◽  
Gabriel Masset ◽  
Jörg Spieldenner
Keyword(s):  
Public Health ◽  
Food Industry ◽  
Dietary Habits ◽  
Food Product ◽  
Cost Effective ◽  
Health Impact ◽  
Dietary Intakes ◽  
Nutrient Profiling ◽  
Multi Stakeholder ◽  
The Impact

The food industry holds great potential for driving consumers to adopt healthy food choices as (re)formulation of foods can improve the nutritional quality of these foods. Reformulation has been identified as a cost-effective intervention in addressing non-communicable diseases as it does not require significant alterations of consumer behaviour and dietary habits. Nutrient profiling (NP), the science of categorizing foods based on their nutrient composition, has emerged as an essential tool and is implemented through many different profiling systems to guide reformulation and other nutrition policies. NP systems should be adapted to their specific purposes as it is not possible to design one system that can equally address all policies and purposes, e.g. reformulation and labelling. The present paper discusses some of the key principles and specificities that underlie a NP system designed for reformulation with the example of the Nestlé nutritional profiling system. Furthermore, the impact of reformulation at the level of the food product, dietary intakes and public health are reviewed. Several studies showed that food and beverage reformulation, guided by a NP system, may be effective in improving population nutritional intakes and thereby its health status. In order to achieve its maximum potential and modify the food environment in a beneficial manner, reformulation should be implemented by the entire food sector. Multi-stakeholder partnerships including governments, food industry, retailers and consumer associations that will state concrete time-bound objectives accompanied by an independent monitoring system are the potential solution.

Moving Evidence to Action: A Strategy to Support the Implementation of Comprehensive Violence Prevention Efforts

2021 ◽  
pp. 152483992110281
Author(s):  
Lindsey Barranco ◽  
Kimberley Freire ◽  
Gayle Holmes Payne
Keyword(s):  
Public Health ◽  
Knowledge Translation ◽  
Violence Prevention ◽  
Implementation Science ◽  
Prevention Strategies ◽  
Public Health Agencies ◽  
Planning Models ◽  
Online Resource ◽  
Working Together ◽  
Specific Implementation

For public health agencies, the pragmatic need to bring together science and practice to affect public health outcomes manifests in the implementation of prevention strategies with the best available evidence. Knowledge translation makes scientific findings understandable to the knowledge user, often through synthesis of the best available evidence. Implementation science promotes the adoption and integration of evidence through prevention strategies implemented within various contexts. Working together, knowledge translation and implementation science can promote the uptake and advancement of scientific and practice-based evidence for strategies that will have the greatest impact across a variety of contexts. Violence Prevention in Practice (VPP) is an online resource designed to help practitioners select, adapt, implement, and evaluate multiple prevention strategies included in five technical packages developed by Centers for Disease Control’s Division of Violence Prevention. A technical package translates the best available evidence into a core set of prevention strategies intended to be broadly implemented. VPP supports communities in using the technical package strategies in combination, drawing on key implementation science principles. In this article, we explain the process for developing VPP and provide a framework that can be used to develop similar guidance in other health promotion areas. The framework explains how both general components, such as selection and adaptation, come together with strategy-specific implementation guidance. Distinct from typical planning models, VPP is not designed as a linear stepwise process, and it allows practitioners to use one or more components alone, as well as helps practitioners link across components as needed.

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