scholarly journals Biomedical Potential of Zinc Oxide Nanoparticles Synthesized using Plant Extracts

Author(s):  
Lakshmi T ◽  
2017 ◽  
Vol 3 (2) ◽  
pp. 26-37 ◽  
Author(s):  
Sagili Jhansi Lakshmi ◽  
Roopa Bai R S ◽  
Sharanagouda H ◽  
Uday kumar Nidoni

The development of nanotechnology is making the interest of researchers towards thesynthesis of nanoparticles for the bioapplication. Metal oxides such as ZnO have received increasing attentionas antibacterial materials in recent years because of their stability under harsh processing conditions, and also because they are generally regarded as safe materials for human beingsand animals. Zinc activates 300 enzymes, and it plays a role in many another phenomenon like growth, membrane stability, bone mineralization, tissue growth, and repair, wound healing and cell signaling.Many studies have shown that ZnO nanoparticles have enhanced antibacterial activity. Use of plant and plant materials for the synthesis of Zinc nanoparticles is relatively new and exciting research field. Various plants were used for the synthesis of nanoparticles using green synthesis method. Nanoparticles were synthesized from all the parts of the plant separately like stem, flower, leaf, latex, root, peel, stem bark and fruits. The prepared nanoparticles of Zinc oxide were characterized by using XRD, FTIR, UV-VIS Spectroscopy, EDAX, Particle size analyzer, TGA, and SEM. The objective of this review was to report on thesynthesis of Zinc oxide nanoparticles by using different plant extracts and their significance in different fields.


2017 ◽  
Vol 40 (6) ◽  
pp. 943-957 ◽  
Author(s):  
Dilaveez Rehana ◽  
D. Mahendiran ◽  
R. Senthil Kumar ◽  
A. Kalilur Rahiman

2021 ◽  
Vol 18 (11) ◽  
Author(s):  
Gee Een LAU ◽  
Che Azurahanim CHE ABDULLAH ◽  
Mohd Sabri MOHD GHAZALI ◽  
Muhamad Syazlie CHE IBRAHIM

Green nanoparticles are receiving great attention due to their broad fields of application. Plant extracts are promising sources, since the synergizing process is easy and cost-effective. Green synergism offers safer nanomaterials for both human health and the environment. The antimicrobial application of prepared nanoparticles is due to special capabilities at the nanoscale size. Green zinc oxide nanoparticles (ZnONPs) from lemongrass and turmeric revealed good antibacterial properties. Antibacterial active compounds were extracted from lemongrass and turmeric using methanol as a solvent. The extracts were introduced to zinc oxide solution to create synergized green ZnONPs and tested for their antibacterial properties. The samples were characterized by means of XRD, SEM, FTIR, and GC-MS. The zones of inhibition of synergized green ZnONPs were successfully measured using the disc diffusion method. The findings using gram-negative bacteria Escherichia coli. showed a higher antibacterial inhibition zone, with a diameter of 1.6 cm. The gram-positive bacteria, Staphylococcus aureus., showed low antibacterial inhibition. The addition of ZnO had positively revealed greater inhibition. Green ZnONPs synthesized using plant extracts will be further tested for various applications. HIGHLIGHTS Green zinc oxide nanoparticles (ZnONPs) prepared from lemongrass and turmerics Plant extracts are significant in reducing and stabilizing metallic ions The synergism of ZnONPs was successfully prepared from plant extract active and evaluated for their antibacterial activity using Staphylococcus aureus and Escherichia coli The zones of inhibition of synergized green ZnONPs measured using the disc diffusion method showed a higher antibacterial inhibition zone Antibacterial activity revealed the potential applications of green synergism of ZnONPs for treatment of contaminated water, medical applications, and cosmetics GRAPHICAL ABSTRACT


2021 ◽  
Vol 28 ◽  
Author(s):  
Farahnaz Behzad ◽  
Erfan Sefidgar ◽  
Azam Samadi ◽  
Wensen Lin ◽  
Iman Pouladi ◽  
...  

: Tuberculosis (TB), induced by Mycobacterium tuberculosis (MTB), is a fatal infectious disease that kills millions of lives worldwide. The emergence of drug-resistant and multidrug-resistant cases is regarded as one of the most challenging threats to TB control due to the low cure rate. Therefore, TB and drug-resistant TB epidemics urge us to explore more effective therapies. The increasing knowledge of nanotechnology has extended to some nanomedicines for disease treatment in the clinic, which also provides novel possibilities for nano-based medicines for TB treatment. Zinc oxide nanoparticles (ZnO NPs) have gained increasing attention for anti-bacterial uses based on their strong ability to induce reactive oxidative species (ROS) and release bactericidal Zinc ions (Zn2+), which are expected to act as novel strategies for TB and drug-resistant TB treatment. Some active herbal medicines from plant extracts have been widely reported to show attractive anti-bacterial activity for infectious treatment, including TB. Here, we summarize the synthesis of ZnO NPs using plant extracts (green synthesized ZnO NPs) and further discuss their potentials for anti-TB treatments. This is the first review article discussing the anti–TB activity of ZnO NPs produced using plant extracts, which might contribute to the further applications of green synthesized ZnO NPs for anti-TB and drug-resistant TB treatment.


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