scholarly journals Synergism of Zinc Oxide Nano-Powder with Active Compound from Turmeric and Lemongrass as Bacterial Inhibitor

2021 ◽  
Vol 18 (11) ◽  
Author(s):  
Gee Een LAU ◽  
Che Azurahanim CHE ABDULLAH ◽  
Mohd Sabri MOHD GHAZALI ◽  
Muhamad Syazlie CHE IBRAHIM
Keyword(s):  
Zinc Oxide ◽  
Plant Extracts ◽  
Zinc Oxide Nanoparticles ◽  
Antibacterial Properties ◽  
Inhibition Zone ◽  
Diffusion Method ◽  
Oxide Nanoparticles ◽  
Disc Diffusion ◽  
Disc Diffusion Method ◽  
Zones Of Inhibition

Green nanoparticles are receiving great attention due to their broad fields of application. Plant extracts are promising sources, since the synergizing process is easy and cost-effective. Green synergism offers safer nanomaterials for both human health and the environment. The antimicrobial application of prepared nanoparticles is due to special capabilities at the nanoscale size. Green zinc oxide nanoparticles (ZnONPs) from lemongrass and turmeric revealed good antibacterial properties. Antibacterial active compounds were extracted from lemongrass and turmeric using methanol as a solvent. The extracts were introduced to zinc oxide solution to create synergized green ZnONPs and tested for their antibacterial properties. The samples were characterized by means of XRD, SEM, FTIR, and GC-MS. The zones of inhibition of synergized green ZnONPs were successfully measured using the disc diffusion method. The findings using gram-negative bacteria Escherichia coli. showed a higher antibacterial inhibition zone, with a diameter of 1.6 cm. The gram-positive bacteria, Staphylococcus aureus., showed low antibacterial inhibition. The addition of ZnO had positively revealed greater inhibition. Green ZnONPs synthesized using plant extracts will be further tested for various applications. HIGHLIGHTS Green zinc oxide nanoparticles (ZnONPs) prepared from lemongrass and turmerics Plant extracts are significant in reducing and stabilizing metallic ions The synergism of ZnONPs was successfully prepared from plant extract active and evaluated for their antibacterial activity using Staphylococcus aureus and Escherichia coli The zones of inhibition of synergized green ZnONPs measured using the disc diffusion method showed a higher antibacterial inhibition zone Antibacterial activity revealed the potential applications of green synergism of ZnONPs for treatment of contaminated water, medical applications, and cosmetics GRAPHICAL ABSTRACT

scholarly journals CRUDE EXTRACTS OF MAGNOLIA ALBA FLOWERS USING N-HEXANE AND METHANOL SOLVENTS AND THEIR ANTI-ACNE POTENTIAL

2021 ◽  
Vol 10 (6) ◽  
pp. 3789-3793
Author(s):  
Sofia Munira
Keyword(s):  
Propionibacterium Acnes ◽  
Methanol Extract ◽  
Antibacterial Properties ◽  
Inhibition Zone ◽  
Positive Control ◽  
Hexane Extract ◽  
Diffusion Method ◽  
Disc Diffusion ◽  
Disc Diffusion Method ◽  
Bacterial Inhibition

This study aimed to test the antibacterial activity of n-hexane and methanol extracts of white cempaka flowers (Magnolia alba) against Propionibacterium acnes bacteria. The extract was obtained by using the maceration method for 72 hours. Each extract was tested for its antibacterial properties using the disc diffusion method with the variant concentration of the extract used was 0.05%; 2%; 4%; 6%; and 8%. The results showed that the methanol extract had a higher inhibition zone than the n-hexane extract. In n-hexane extract, the lowest concentration of 0.05% showed an inhibition zone of 6.6 mm and the highest concentration of 8% had an inhibition zone of 9.6 mm. Whereas in methanol extract, the inhibition zone obtained was 7.3 mm at a low concentration of 0.05%, but at the highest concentration of 8% the inhibition zone obtained was 11.6 mm. The effect of extract concentration on the diameter of the inhibition zone formed is very significant (directly proportional), where the higher the concentration used, the larger the diameter of the inhibition zone produced. Antibacterial testing for both extracts showed a weak (< 10 mm) to moderate (> 10 mm) bacterial inhibition, which was similar with the inhibition zone obtained from the positive control (11-11.3 mm; moderate bacterial inhibition).

scholarly journals Green Fabrication of Zinc Oxide Nanoparticles Using Phlomis Leaf Extract: Characterization and In Vitro Evaluation of Cytotoxicity and Antibacterial Properties

Molecules ◽  
2021 ◽  
Vol 26 (20) ◽  
pp. 6140
Author(s):  
Amal A. Alyamani ◽  
Salim Albukhaty ◽  
Salman Aloufi ◽  
Faizah A. AlMalki ◽  
Hassan Al-Karagoly ◽  
...  
Keyword(s):  
Zinc Oxide ◽  
Zinc Oxide Nanoparticles ◽  
Leaf Extract ◽  
Antibacterial Properties ◽  
Normal Fibroblast ◽  
Diffusion Method ◽  
Oxide Nanoparticles ◽  
Zno Nps ◽  
Disk Diffusion Method

Green nanoparticle synthesis is an environmentally friendly approach that uses natural solvents. It is preferred over chemical and physical techniques due to the time and energy savings. This study aimed to synthesize zinc oxide nanoparticles (ZnO NPs) through a green method that used Phlomis leaf extract as an effective reducing agent. The synthesis and characterization of ZnO NPs were confirmed by UV-Vis spectrophotometry, Fourier Transform Infrared Spectroscopy (FTIR), X-Ray Diffraction (XRD), Dynamic light scattering (DLS), Zeta potential, and Field Emission Scanning Electron Microscope (FESEM) techniques. In vitro cytotoxicity was determined in L929 normal fibroblast cells using MTT assay. The antibacterial activity of ZnO nanoparticles was investigated using a disk-diffusion method against S. aureus and E. coli, as well as minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) content concentrations. XRD results confirmed the nanoparticles’ crystalline structure. Nanoparticle sizes were found to be around 79 nm by FESEM, whereas the hydrodynamic radius of nanoparticles was estimated to be around 165 3 nm by DLS. FTIR spectra revealed the formation of ZnO bonding and surfactant molecule adsorption on the surface of ZnO NPs. It is interesting to observe that aqueous extracts of phlomis leave plant are efficient reducing agents for green synthesis of ZnO NPs in vitro, with no cytotoxic effect on L929 normal cells and a significant impact on the bacteria tested.

scholarly journals ANTIMICROBIAL AND PHOTOCATALYTIC PROPERTIES OF DOPED AND UNDOPED ZINC OXIDE NANOPARTICLES

2020 ◽  
Vol 11 (2) ◽  
Author(s):  
Savka Vračević ◽  
Aleksandra Šmitran ◽  
Sanja Pržulj ◽  
Dragana Gajić ◽  
Mladena Malinović ◽  
...  
Keyword(s):  
Zinc Oxide ◽  
Zinc Oxide Nanoparticles ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Trisodium Citrate ◽  
Black Tea ◽  
Inhibition Zone ◽  
Photocatalytic Properties ◽  
Diffusion Method ◽  
Oxide Nanoparticles ◽  
Antimicrobial Efficiency

In this paper, zinc oxide nanoparticles doped with copper (ZnO/CuNP) were synthesized by using black and green tea, vitamin C and trisodium citrate as a reduction agent. Antimicrobial and photocatalytic properties were tested. The antimicrobial activity of the doped synthesized ZnO NP against the clinical isolates of Acinetobacter baumannii and methicillin resistant Staphylococcus aureus (MRSA) was performed by the agar well diffusion method. ZnO NP with all four reduction agents showed good antimicrobial efficiency against both microorganisms, with similar inhibition zone. Photocatalytic activity was more pronounced in case of undoped, pure ZnO nanoparticles, while the best results for doped ZnO samples were obtained for ZnO/Cu NPs using black tea.

scholarly journals Antibacterial Activity of The Iron-Zinc Oxide Nanoparticles Synthesized Via Electric Discharge Method

2021 ◽  
Author(s):  
Fereshteh Shahbazi ◽  
Reza Ahmadi ◽  
Mohammad Noghani ◽  
Gholamreza Karimi
Keyword(s):  
Zinc Oxide ◽  
Electrical Discharge ◽  
Zinc Oxide Nanoparticles ◽  
Viral Infections ◽  
Antibacterial Properties ◽  
Oxide Nanoparticles ◽  
Gram Negative Bacteria ◽  
Discharge Method ◽  
Electric Discharge Method ◽  
Novel Antibiotics

Abstract With the increase in diseases caused by bacterial and viral infections, the need for antibiotics has increased. On the other hand, by creating drug resistance to organicmoietiesbased antibiotics, novel antibiotics have attracted the attention of researchers.Nano-scale metal oxides are increasingly being considered for medical applications, especially as antibacterial agents.In this study, iron oxide nanoparticles (IONPs) and zinc oxide nanoparticles (ZONPs) were prepared via electrical discharge method in liquid medium by changing parameters such as wire diameter and electric current intensity. Synthesized NPs were evaluated by XRD, UV_Visible, FE_SEM, EDS, HR_TEM and TEM analyzes. Also, the antibacterial properties of these nanoparticles were evaluated in different ways against gram-positive and gram-negative bacteria.

scholarly journals Photocatalytic activity of biogenic zinc oxide nanoparticles: In vitro antimicrobial, biocompatibility, and molecular docking studies

2021 ◽  
Vol 10 (1) ◽  
pp. 1079-1091
Author(s):  
Mahboob Alam
Keyword(s):  
Zinc Oxide ◽  
Molecular Docking ◽  
Zinc Oxide Nanoparticles ◽  
Dye Degradation ◽  
Antimicrobial Properties ◽  
Morphological Properties ◽  
Diffusion Method ◽  
Oxide Nanoparticles ◽  
Zno Nps ◽  
Receptor Binding Site

Abstract The biogenic synthesis of zinc oxide nanoparticles (ZnO NPs) with pinecone extract (PCE) as a reducing agent and antibacterial agent was explored. The current study aims to investigate the biosynthesis of ZnO NPs and their effect on photocatalytic dye degradation and antimicrobial properties. The physical, chemical, and morphological properties of biogenic ZnO NPs synthesized using PCE were investigated using advanced spectroscopy techniques such as Fourier transform infrared spectroscopy (FTIR), UV-visible spectroscopy, transmission electron microscopy (TEM) analysis, selected area electron diffraction (SAED), and X-ray diffraction (XRD) techniques. The photocatalytic degradation of methylene blue was measured spectrophotometrically using biogenic ZnO NPs as nanocatalysts, and decolonization of solution indicates dye degradation gradually as exposure duration increases. The antimicrobial properties of ZnONPs against the tested pathogenic strains were demonstrated using the disc diffusion method. The antimicrobial efficacy of ZnONPs was further explained using molecular docking analysis. Confirmation of the lowest binding energy was used to predict receptor binding site with NPs in order to understand the mechanistic approach. ZnONPs are likely to interact with pathogens via mechanical enfolding, which could be one of the major toxicity actions of ZnONPs against strains. Furthermore, the nontoxicity and biocompatibility of ZnO NPs were studied, revealing impressive hemocompatibility with red blood cells (RBCs) and no significant toxicity to Brine shrimps at lower ZnONP concentrations.

Preparation and Antibacterial Performances of Electrocatalytic Zinc Oxide Nanoparticles with Diverse Morphologies

2021 ◽  
Vol 17 (9) ◽  
pp. 1824-1829
Author(s):  
Junlin Li ◽  
Xiangfei Li ◽  
Dong Liang ◽  
Xiaojuan Zhang ◽  
Qing Lin ◽  
...  
Keyword(s):  
Zinc Oxide ◽  
Surface Area ◽  
Zinc Oxide Nanoparticles ◽  
Average Particle Size ◽  
Three Dimensional ◽  
Diffusion Method ◽  
Oxide Nanoparticles ◽  
Average Particle ◽  
X Ray Diffraction ◽  
Zno Nps

This study exploits the potential of zinc oxide nanoparticles (ZnO-NPs) with diverse morphologies as catalysts and antibacterial agent. Spherical ZnO-NPs, rod-shaped ZnO-NPs and flower-shaped ZnO-NPs were prepared by microemulsion method, solvent heat method and hydrothermal method, respectively. The structural characterizations of samples were investigated by X-ray diffraction (XRD) and scanning electron microscopy (SEM) techniques. XRD results revealed the formation of spherical ZnO-NPs, rod-shaped ZnO-NPs and flower-shaped ZnO-NPs were all wurtzite crystal structure. SEM results showed that spherical ZnO-NPs had an average particle size of 30–40 nm, rod-shaped ZnO-NPs were about 500 nm long and 100 nm wide with obvious hexagonal crystals. Flower-shaped ZnO-NPs had a three-dimensional appearance with obvious petals. Results of electrochemical HER (Hydrogen evolution reaction) experiments revealed that spherical ZnO-NPs exhibited the highest electrocatalytic activity at the lowest potential voltage due to their largest specific surface area. The antibacterial property of ZnO-NPs samples were studied by the optical density method and disc diffusion method. All samples had antibacterial effects against E. coli. and flower-shaped ZnO-NPs showed the best antibacterial activity due to the largest surface area in comparison with spherical ZnO-NPs and rod-shaped ZnO-NPs, which promised the maximum Zn2+ release as bactericide mechanism that registered in the case of different ZnO-NPs morphologies.

Synthesis and Antimicrobial Properties of Zinc Oxide Nanoparticles

2020 ◽  
Vol 20 (10) ◽  
pp. 5977-5996 ◽  
Author(s):  
Saee Gharpure ◽  
Balaprasad Ankamwar
Keyword(s):  
Zinc Oxide ◽  
Zno Nanoparticles ◽  
Zinc Oxide Nanoparticles ◽  
Metal Oxide Nanoparticles ◽  
Antibacterial Properties ◽  
Antimicrobial Properties ◽  
Physical Contact ◽  
Oxide Nanoparticles ◽  
Synthesis Methods ◽  
Promising Alternative

With increase in incidence of multidrug resistant pathogens, there is a demand to adapt newer approaches in order to combat these diseases as traditional therapy is insufficient for their treatment. Use of nanotechnology provides a promising alternative as antimicrobial agents as against traditional antibiotics. Metal oxides have been exploited for a long times for their antimicrobial properties. Zinc oxide nanoparticles (ZnO NPs) are preferred over other metal oxide nanoparticles because of their bio-compatible nature and excellent antibacterial potentials. The basic mechanism of bactericidal nature of ZnO nanoparticles includes physical contact between ZnO nanoparticles and the bacterial cell wall, generation of reactive oxygen species (ROS) as well as free radicals and release of Zn2+ ions. This review focuses on different synthesis methods of ZnO nanoparticles, various analytical techniques frequently used for testing antibacterial properties, mechanism explaining antibacterial nature of ZnO nanoparticles as well as different factors affecting the antibacterial properties.

scholarly journals Green synthesis of zinc oxide nanoparticles using different plant extracts and their antibacterial activity against Xanthomonas oryzae pv. oryzae

2019 ◽  
Vol 47 (1) ◽  
pp. 341-352 ◽  
Author(s):  
Solabomi Olaitan Ogunyemi ◽  
Yasmine Abdallah ◽  
Muchen Zhang ◽  
Hatem Fouad ◽  
Xianxian Hong ◽  
...  
Keyword(s):  
Zinc Oxide ◽  
Antibacterial Activity ◽  
Green Synthesis ◽  
Plant Extracts ◽  
Zinc Oxide Nanoparticles ◽  
Xanthomonas Oryzae ◽  
Oxide Nanoparticles

Biocomposite of Ultra-High Molecular Weight Polyethylene and Hydroxyapatite with Antibacterial Properties by the Incorporation of Zinc Oxide Nanoparticles

2018 ◽  
Vol 930 ◽  
pp. 258-263 ◽  
Author(s):  
R. Galli ◽  
M. Soares ◽  
L.P. Domingos ◽  
E.B. Batiston ◽  
Luciano Luiz Silva ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Zinc Oxide ◽  
High Molecular Weight ◽  
Zinc Oxide Nanoparticles ◽  
Antimicrobial Property ◽  
Antibacterial Properties ◽  
Oxide Nanoparticles ◽  
Standard Composition ◽  
Increasing Demand ◽  
Ultra High Molecular Weight

With the increasing demand of biomaterials, numerous studies have been developed seeking to improve its properties through new obtaining and manufacturing processes. This work aimed to aggregate antimicrobial property to a biocomposite constituted of a matrix of ultra-high molecular weight polyethylene (UHMWPEE) and hydroxyapatite, by the incorporation of zinc oxide nanoparticles. The samples were prepared based on a standard composition containing 95.0 wt% of UHMWPEE and 5.0 wt% of hydroxyapatite (blank). Three compositions were evaluated ranging the amount of zinc oxide nanoparticles incorporated in the standard sample. It was observed that the increase of zinc oxide concentration aggregate a good antibacterial property in the samples tested without cause significant changes in the mechanical properties of the composites.

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