Vitamin D Deficiency as a Cause of Hip Fractures in the Elderly

Background: Hip fractures are devastating injuries that most often affect the elderly and have a tremendous impact on both the health care system and society in general. Approximately 97% occur in patients over 50 years of age. It has been a general belief that rickets and vitamin D deficiency are uncommon problems in India because of abundant sunshine. Hence the aim was to identify patients with hip fractures and to attain the vitamin D levels in these patients.Methods: The study was a descriptive type of study. Patients who fulfilled the inclusion criteria were included in the study. A total of 154 patients were included in the study. Patients were assessed clinically, with a thorough history and physical examination. The symptoms and signs elicited were recorded in a performa.Results: Neck of femur (NOF) was more common in female patients and intertrochanteric (IT) fracture was common in male patients. These fractures were mainly seen in the age group between 61 to 70 years of age for hip fractures. It was also noted that anaemia was prevalent in both male and female patients and the overall vitamin D deficiency was 76% of the total number of patients with more predominant (84.6%) in female patients.Conclusions: Treatment of the vitamin D deficiency reduces the chances of fall, morbidity and financial burden on the patient when fractures occur. The treatment of vitamin D deficiency will improve the quality of life overall. Hence the need for food fortification and supplementation in elderly Indian population.

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Preoperative severe vitamin D deficiency is a significant independent risk factor for poorer functional outcome and quality of life 6 months after surgery for fragility hip fractures

Osteoporosis International ◽

10.1007/s00198-021-05970-y ◽

2021 ◽

Author(s):

D.S. Sim ◽

K. Tay ◽

T.S. Howe ◽

S.B.J. Koh

Keyword(s):

Quality Of Life ◽

Vitamin D ◽

Risk Factor ◽

Functional Outcome ◽

Vitamin D Deficiency ◽

Hip Fractures ◽

Independent Risk Factor ◽

Severe Vitamin ◽

Significant Independent Risk Factor

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HIP FRACTURES AND OCCULT VITAMIN D DEFICIENCY

Southern Medical Journal ◽

10.1097/00007611-199910000-00020 ◽

1999 ◽

Vol 92 (10) ◽

pp. 1031

Author(s):

MS LeBoff ◽

L Kohlmeier ◽

S Hurwitz

Keyword(s):

Vitamin D ◽

Vitamin D Deficiency ◽

Hip Fractures

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A Resident-led Initiative Improves Screening and Treatment for Vitamin D Deficiency in Patients with Hip Fractures

Clinical Orthopaedics and Related Research ◽

10.1007/s11999-016-5036-4 ◽

2016 ◽

Vol 475 (1) ◽

pp. 264-270 ◽

Cited By ~ 1

Author(s):

Drew A. Lansdown ◽

Amanda Whitaker ◽

Rosanna Wustrack ◽

Aenor Sawyer ◽

Erik N. Hansen

Keyword(s):

Vitamin D ◽

Vitamin D Deficiency ◽

Hip Fractures

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VITAMIN D DEFICIENCY AND HIP FRACTURES

Southern Medical Journal ◽

10.1097/00007611-199908000-00021 ◽

1999 ◽

Vol 92 (8) ◽

pp. 836

Author(s):

&NA;

Keyword(s):

Vitamin D ◽

Vitamin D Deficiency ◽

Hip Fractures

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Prevalence of 25-hydroxyvitamin D deficiency in subgroups of elderly persons with anemia: association with anemia of inflammation

Blood ◽

10.1182/blood-2010-09-309708 ◽

2011 ◽

Vol 117 (10) ◽

pp. 2800-2806 ◽

Cited By ~ 69

Author(s):

Todd S. Perlstein ◽

Reena Pande ◽

Nancy Berliner ◽

Gary J. Vanasse

Keyword(s):

Vitamin D ◽

Vitamin D Deficiency ◽

Serum Levels ◽

The Elderly ◽

Vitamin D Supplementation ◽

World Health ◽

Elderly Persons ◽

Increased Risk ◽

Health Organization ◽

Anemia Of Inflammation

AbstractAnemia and vitamin D deficiency are conditions that both result in significant morbidity and increase with age. The potential relationship between them remains poorly understood, particularly in the elderly. We used the Third National Health and Nutrition Examination Survey to examine the association of vitamin D deficiency with anemia subtypes in persons aged ≥ 60 years. Vitamin D deficiency was defined as serum levels < 20 ng/mL, and anemia was defined according to World Health Organization criteria. Vitamin D deficiency was associated with anemia prevalence independent of age, sex, or race/ethnicity (odds ratio, 1.47; 95% confidence interval, 1.06-2.05; P = .02) and varied significantly by anemia subtype (P overall = .003). The prevalence of vitamin D deficiency was 33.3% in the nonanemic population, 56% in anemia of inflammation (AI; P = .008), and 33.0% in unexplained anemia (P = .55). Non-Hispanic blacks had a 7-fold increased risk of AI compared with whites, and this was partially attenuated after adjusting for vitamin D deficiency. These data show that vitamin D deficiency is associated with specific subtypes of anemia in the elderly, especially in those with AI. Vitamin D may suppress inflammatory pathways, and studies to determine whether vitamin D supplementation ameliorates AI are warranted.

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Does vitamin D deficiency increase orthostatic hypotension risk in the elderly patients?

Archives of Gerontology and Geriatrics ◽

10.1016/j.archger.2014.03.008 ◽

2014 ◽

Vol 59 (1) ◽

pp. 74-77 ◽

Cited By ~ 27

Author(s):

Pinar Soysal ◽

Adnan Yay ◽

Ahmet Turan Isik

Keyword(s):

Vitamin D ◽

Elderly Patients ◽

Orthostatic Hypotension ◽

Vitamin D Deficiency ◽

The Elderly

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Nutrihealth Study: Seasonal Variation in Vitamin D Status Among the Slovenian Adult and Elderly Population

Nutrients ◽

10.3390/nu12061838 ◽

2020 ◽

Vol 12 (6) ◽

pp. 1838 ◽

Cited By ~ 1

Author(s):

Maša Hribar ◽

Hristo Hristov ◽

Matej Gregorič ◽

Urška Blaznik ◽

Katja Zaletel ◽

...

Keyword(s):

Vitamin D ◽

Seasonal Variation ◽

Vitamin D Deficiency ◽

Elderly Population ◽

Sun Exposure ◽

Epidemiological Data ◽

The Elderly ◽

Vitamin D Insufficiency ◽

Ultraviolet B ◽

Vitamin D Status

Several studies conducted around the world showed substantial vitamin D insufficiency and deficiency among different population groups. Sources of vitamin D in the human body include ultraviolet B (UVB)-light-induced biosynthesis and dietary intake, but people’s diets are often poor in vitamin D. Furthermore, in many regions, sun exposure and the intensity of UVB irradiation during wintertime are not sufficient for vitamin D biosynthesis. In Slovenia, epidemiological data about vitamin D status in the population were investigated through a national Nutrihealth study—an extension to the national dietary survey SI.Menu (2017/18). The study was conducted on a representative sample of 125 adult (18–64 years) and 155 elderly (65–74 years old) subjects, enrolled in the study in different seasons. Their vitamin D status was determined by measuring the serum 25-hydroxy-vitamin D (25(OH)D) concentration. Thresholds for vitamin D deficiency and insufficiency were 25(OH)D levels below 30 and 50 nmol/L, respectively. Altogether, 24.9% of the adults and 23.5% of the elderly were found to be vitamin D deficient, while an insufficient status was found in 58.2% and 62.9%, respectively. A particularly concerning situation was observed during extended wintertime (November–April); vitamin D deficiency was found in 40.8% and 34.6%, and insufficient serum 25(OH)D levels were observed in 81.6% and 78.8%, respectively. The results of the study showed high seasonal variation in serum 25(OH)D levels in both the adult and elderly population, with deficiency being especially pronounced during wintertime. The prevalence of this deficiency in Slovenia is among the highest in Europe and poses a possible public health risk that needs to be addressed with appropriate recommendations and/or policy interventions.

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