scholarly journals Evaluation of co-relation between hip fractures and vitamin D level

Author(s):  
Pragnesh Patel ◽  
Vimal P. Gandhi

<p class="abstract"><strong>Background:</strong> Hip fractures are devastating injuries that most often affect the elderly and have a tremendous impact on both the health care system and society in general. Approximately 97% occur in patients over 50 years of age. It has been a general belief that rickets and vitamin D deficiency are uncommon problems in India because of abundant sunshine. Hence the aim was to identify patients with hip fractures and to attain the vitamin D levels in these patients.</p><p class="abstract"><strong>Methods:</strong> The study was a descriptive type of study. Patients who fulfilled the inclusion criteria were included in the study. A total of 154 patients were included in the study. Patients were assessed clinically, with a thorough history and physical examination. The symptoms and signs elicited were recorded in a performa.<strong></strong></p><p class="abstract"><strong>Results:</strong> Neck of femur (NOF) was more common in female patients and intertrochanteric (IT) fracture was common in male patients. These fractures were mainly seen in the age group between 61 to 70 years of age for hip fractures. It was also noted that anaemia was prevalent in both male and female patients and the overall vitamin D deficiency was 76% of the total number of patients with more predominant (84.6%) in female patients.</p><p class="abstract"><strong>Conclusions:</strong> Treatment of the vitamin D deficiency reduces the chances of fall, morbidity and financial burden on the patient when fractures occur. The treatment of vitamin D deficiency will improve the quality of life overall. Hence the need for food fortification and supplementation in elderly Indian population.</p>

2006 ◽  
Vol 76 (5) ◽  
pp. 307-313 ◽  
Author(s):  
Kocjan ◽  
Tan ◽  
Conway ◽  
Prelevic

Vitamin D deficiency and insufficiency may further increase fracture risk in patients with decreased bone mineral density. We audited serum 25-hydroxyvitamin D (25OHD) concentrations in patients with osteopenia or osteoporosis attending endocrine osteoporosis clinics in North London between January 1998 and September 2001. The total number of patients analyzed was 448 (age range 17–89 years), with 191 patients being < 50 years old (42.6%). The following cut-off points for serum 25OHD were used: levels ≤ 30 nmol/L for deficiency, > 30–50 nmol/L for insufficiency, and > 50 nmol/L for sufficiency. The overall prevalence of vitamin D deficiency was 30.5% and of vitamin D insufficiency was 35.9%. Vitamin D deficiency was as prevalent in young patients as in older ones: the prevalence of serum 25OHD ≤ 30 nmol/L in those < 50 years of age was 33.0% (n = 63 of 191), compared with 31.1% (n = 80 of 257) in patients aged ≥ 50 years. Our results indicate that vitamin D deficiency and insufficiency is a common problem in patients with osteopenia or osteoporosis. This situation persists despite dietary advice and prescription of vitamin D3 supplementation. Vitamin D deficiency affects all age groups, not merely the elderly.


BJPsych Open ◽  
2021 ◽  
Vol 7 (S1) ◽  
pp. S86-S87
Author(s):  
Vasudevan Krishnan ◽  
Ciara Doyle ◽  
Maciej Rusilowicz

AimsTo survey the prevalence of monitoring of vitamin D on an inpatient ward.To audit the treatment if there is identified vitamin D deficiency or insufficiencyTo compare differences between findings in auditsMethodAll inpatients admitted to Milford centre between August 2019 and August 2020 were selected as part of the sample size.Data were collected by FY1 and FY2Patients’ laboratory results were accessed to determine vitamin D levels.E-notes were used to conclude who were vitamin D sufficient or deficient for treatmentThe standard for the audit were as per:Management of vitamin D deficiency or insufficiency in adults – CKS (2018)The above was based on National Osteoporosis Society (NOS) guideline Vitamin D and bone health: a practical clinical guideline for patient management [National Osteoporosis Society, 2013] and Scientific Advisory Committee on Nutrition (SACN) guidelineResult201748/188 patients had vitamin D levels measured36/48 patients had sufficient vitamin D levels12/48 patients were either deficient or insufficient12/12 patients were treated where found deficient or insufficient202090/115 patients had vitamin D levels measured47/90 patients had sufficient vitamin D Levels43/90 patients had either insufficient or deficient vitamin D levels22/43 patients had treatment documented in noted where found deficient or insufficientConclusionDifficult to make comparisons with previous audit due to difference in number of patients testedVitamin D is routinely tested on Milford ward on admission hence the large number compared to the last audit52% had noted to have sufficient levels of vitamin DConcerning were results that only 51% of those deemed to have insufficient or deficient were treated based on notesPotential reasons could be:Prescribed in medication card and not documented in notes.Vitamin D results checked in another ward, no supplementation given, and then transferred to Milford house.Patients refused treatment but not documented adequately.Patient discharged before results were received due to quick aroundResults were deemed insufficient in terms of the range but very close to normal hence decision made not to start supplementationResults to be disseminated with medical and nursing colleaguesRe-audit in September 2021


2021 ◽  
Vol 15 (11) ◽  
pp. 3499-3501
Author(s):  
Maria Mehmood ◽  
Zobia Mubarak ◽  
Irum Javed ◽  
Sarah Arif ◽  
Sikandar Ali Khan ◽  
...  

Aim: The goal of this study is to find out how common vitamin D deficiency is in patients with corona virus disease and what the consequences are. Study Design: Observational /Prospective Place and Duration: Institute of Basic medical sciences, Khyber Medical University (KMU), Jan 2021-Oct 2021. Materials & Methods: This study included 120 patients of both genders who had been diagnosed with covid-19. Patients ranged in age from 15 to 75 years. After receiving written agreement, demographically detailed such as age, sex, and BMI were recorded. All of the patients had a 5 mL blood sample obtained to check their vitamin D levels. 25(OH)D < 25 nmol/L (10 ng/dL) was considered severe Vitamin D insufficiency. The prevalence of vitamin D insufficiency as well as negative effects were investigated. SPSS 23.0 was used to analyse the data. Results: The mean age of the 120 patients was 40.11±8.64 years, with 68 (56.7%) males and 52 (43.3%) females. There were 52 patients (43.3%) with severe vitamin D insufficiency. There were 17 deaths of the total number of patients in the study. Vitamin D deficiency was associated with a higher mortality rate in patients with covid-19 disease than in those who had normal levels of vitamin D, a finding that was statistically significant at the 0.05 level. Conclusion: It was found that severe deficiency of vitamin D and death in individuals with covid-19 illness had a strong association. Keywords: Mortality, Vitamin D Deficiency, Covid-19,


2014 ◽  
Vol 170 (5) ◽  
pp. 667-675 ◽  
Author(s):  
Maria Samefors ◽  
Carl Johan Östgren ◽  
Sigvard Mölstad ◽  
Christina Lannering ◽  
Patrik Midlöv ◽  
...  

ObjectiveInstitutionalised elderly people at northern latitudes may be at elevated risk for vitamin D deficiency. In addition to osteoporosis-related disorders, vitamin D deficiency may influence several medical conditions conferring an increased mortality risk. The aim of this study was to explore the prevalence of vitamin D deficiency and its association with mortality.DesignThe Study of Health and Drugs in the Elderly (SHADES) is a prospective cohort study among elderly people (>65 years) in 11 nursing homes in Sweden.MethodsWe analysed the levels of 25-hydroxyvitamin D3(25(OH)D3) at baseline. Vital status of the subjects was ascertained and hazard ratios (HRs) for mortality according to 25(OH)D3quartiles were calculated.ResultsWe examined 333 study participants with a mean follow-up of 3 years. A total of 147 (44%) patients died within this period. Compared with the subjects in Q4 (25(OH)D3>48 nmol/l), HR (with 95% CI) for mortality was 2.02 (1.31–3.12) in Q1 (25(OH)D3<29 nmol/l) (P<0.05); 2.03 (1.32–3.14) in Q2 (25(OH)D330–37 nmol/l) (P<0.05) and 1.6 (1.03–2.48) in Q3 (25(OH)D338–47 nmol/l) (P<0.05). The mean 25(OH)D3concentration was 40.2 nmol/l (s.d. 16.0) and 80% had 25(OH)D3below 50 nmol/l. The vitamin D levels decreased from baseline to the second and third measurements.ConclusionsVitamin D deficiency was highly prevalent and associated with increased mortality among the elderly in Swedish nursing homes. Strategies are needed to prevent, and maybe treat, vitamin D deficiency in the elderly in nursing homes and the benefit of vitamin D supplementation should be evaluated in randomised clinical trials.


BJPsych Open ◽  
2021 ◽  
Vol 7 (S1) ◽  
pp. S12-S12
Author(s):  
Claire Bustin ◽  
Shay-Anne Pantall ◽  
Jeremy Rampling

AimsTo audit the investigation, identification and treatment of vitamin D deficiency within Women's Secure Services.BackgroundIt has been suggested that vitamin D and vitamin D deficiency may play a role in the pathogenesis of psychiatric illness. There is evidence that vitamin D inadequacy is prevalent among patients in long-term hospital settings. Patients within secure hospitals are considered to be at high risk due to their often lengthy admissions, having been transferred from other hospital or prison settings. Ardenleigh in Birmingham is a blended female secure unit. Here we present the findings of an audit, completed in 2019, of vitamin D monitoring and treatment in this service.MethodA retrospective review of electronic patient records, for all inpatients admitted within women's secure services at Ardenleigh as of 1st September 2019 (n = 27). Standards were based on the Trust accepted guidelines for management of vitamin D deficiency.ResultKey findings included:-The majority of inpatients were Caucasian (44%) and African-Caribbean (41%). Median age was 31 years (range 20–56).Approximately two-thirds (60%) had been in hospital for over a year.89% of patients had their vitamin D level checked at some point during admission.Of those checked, 25% were tested within 1 week of admission. Seven patients were tested after being in hospital for over one year (30%).Only 25% of patients tested were found to have adequate vitamin D levels. Nine patients were found to have insufficient levels of vitamin D (37.5%) or deficiency (37.5%).89% of those identified as requiring treatment were prescribed supplementation, of which the majority was prescribed at the correct dose for the appropriate duration (94%). One patient refused treatment. Of those with sufficient levels, 67% were prescribed ongoing maintenance treatment due to previously detected deficiency.Of those found to have sufficient vitamin D in the last 12 months (n = 14), 71% were continued on maintenance treatment.ConclusionWe identified a high prevalence of vitamin D insufficiency in women admitted to secure services. Testing was delayed for a number of patients from the point of admission. However, once identified, the vast majority of those in need of treatment were managed appropriately by the medical team. We advise that vitamin D be considered an essential routine blood test at the point of admission to minimise delays in identifying those with deficiency and establishing necessary supplementation.


2021 ◽  
Vol 2 (1) ◽  
pp. 4
Author(s):  
Abdul Latif Khattak ◽  
Abdul Moueed Tariq ◽  
Syed Karamat Hussain Shah Bukhari ◽  
Shahzeb Ahmad Satti ◽  
Raffi ud Din ◽  
...  

Objective: To determine frequency of vitamin D deficiency in female patients presenting with non-specific musculoskeletal symptoms.Study Design: Descriptive cross sectional.Place and Duration of Study: The study was conducted in Medical Outpatient Department (OPD), Combined Military Hospital (CMH) Quetta from 30th November 2018 to 30th May 2019.Materials and Methods: A total of 150 female patients with nonspecific musculoskeletal symptoms were included. Patients on vitamin D supplements, osteopenia, osteoporosis, chronic kidney disease, neuropathies, cancers, diabetes mellitus, iron and Vitamin B12 deficiency were excluded. Data including gender, age and presence of bone pain, muscle aches, bone tenderness and fracture was collected. SPSS v 17 was used for data analysis. Chi-square test was applied to test for associations,  p value less than 0.05 was taken as significant.Results: The mean age was 37.20 + 13.30 years. Mean Vitamin D levels were 14.89 + 7.76 ng/ml with range from 3.10 to 35.67ng/ml. Participants with vitamin D3 < 10 ng/ml were 24% (n=36), < 20 ng/ml were 54% (n= 81), <30 ng/ml were 12 % (n=18) and only 10 % (n= 15) had optimal Vitamin D3 levels. Among the study population 82% (n=123) had bone pains, 88.6% (n=33) had muscle aches and weakness, 72.66% (n=109) had bone tenderness while only 4% (n=6) had fractures. There was a statistically significant association between symptoms and vitamin D3 deficiency with p value <0.001.Conclusion: This study showed that vitamin D deficiency is prevalent in our female populationand it presents with nonspecific musculoskeletal symptoms.


2020 ◽  
Vol 32 (1) ◽  
Author(s):  
Ahmed Rabiee ◽  
Mohamed AboElsoud ◽  
Sayed M. Seif El Nasr ◽  
Sameh Abouzeid

Abstract Background Vitamin D deficiency increases muscle weakness and pain leading to reduced power and function, increased bone turnover and increased risk of falls and hip fractures in elderly. We postulated that vitamin D deficiency in sunny Egypt should be lower than western countries so we screen for prevalence of vitamin D deficiency among all elderly patient admitted to orthogeriatric unit by fracture hip. Results Our study showed that vitamin D deficiency is common in elderly Egyptian patients admitted to orthogeriatric unit with hip fractures. Of the study group (n 290 patients) vitamin D levels were sufficient (30 ng/dl or more) in 24 patients (8.3%) and insufficient (between 20 ng and 30 ng) in 125 patients (43.1%) and deficient (less than 20) in 141 patients (48.7%). Among the study group, female patients had lower levels of vitamin D (18.8 ± 6.9) compared to males (20.5 ± 6.7) P value 0.034. Although our study failed to link different levels of vitamin D with activity of daily life: P value was (0.116) in bathing, (0.058) in dressing, (0.115) in toileting and (054) in transfer. A little difference was found in feeding (0.036) and previous fall (0.011) and cognitive impairment; MiniCOG < 3 P value 0.017. Both previous falls and cognitive decline are in turn linked to increased fracture risk Conclusion Hypovitaminosis D is common among older patients with hip fractures even in sunny Egypt remaining slightly lower than its prevalence in western countries. Although no direct significant correlations with activity of daily life, vitamin D deficiency was associated with higher risks of previous falls and cognitive impairment both in turn increases the risk of fractures.


2016 ◽  
Vol 9 ◽  
pp. NMI.S33747 ◽  
Author(s):  
Syed Asher Hussain Zaidi ◽  
Gurjit Singh ◽  
Olukolade Owojori ◽  
Ram Kela ◽  
Shirley Spoors ◽  
...  

Vitamin D deficiency and insufficiency may further increase fracture risk in patients with decreased bone mineral density. A cross-sectional study on serum vitamin D concentrations in medical inpatients was conducted at Bassetlaw District General Hospital between April 2014 and January 2015 (10 months), and the relationship of serum vitamin D concentrations with calcium and alkaline phosphatase was evaluated. 25-Hydroxyvitamin D immunoassays were used and analyzed in the local laboratory. The total number of patients analyzed was 200, age range 18-99 years, with mean age of 76 years. The most common presentation was found to be fall/collapse. The following cutoff points for serum vitamin D were used: levels ≤30 nmol/L for severe deficiency, >30-50 nmol/L for moderate deficiency, >50-75 nmol/L for mild deficiency, and anything above 75 nmol/L as normal. Of the 209 participants examined, 78 (37.3%) participants had mild vitamin D deficiency, 54 (25.8%) participants had moderate vitamin D deficiency, 68 (32.5%) participants had severe vitamin D deficiency, and 9 (4.3%) participants with low vitamin D levels died during their admission. Of the 122 moderate/severe patients, 70 (57.4%) patients had their vitamin D deficiency treated, according to local Trust guidelines. The study found no relationship between serum calcium levels and vitamin D deficiency, whereas patients’ alkaline phosphatase levels were found to be higher with increased severity of vitamin D deficiency. The study examined the implications of untreated severe/moderate vitamin D deficiency compared to treated deficiency, in terms of the frequency of readmission with similar complaints. It was found that the rate of readmission within one year in patients who were not treated was 57%, compared to 48% in patients whose vitamin D deficiency was treated. Presenting after falls was a recurring theme. It was concluded that even if moderate vitamin D deficiency can be asymptomatic, it is important to correct it as it can have an impact on morbidity and readmission rates in the long term.


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