scholarly journals Clinical Manifestation and Outcomes of Thrombolytic and Consevative Therapy in Covid-19 Patients with ST-Segment Elevation Pattern: A Case Series

2021 ◽  
Vol 2 (2) ◽  
pp. 73
Author(s):  
Raditya Rizki Muhammad ◽  
Nadya Anisah ◽  
Arief Bowo Kurniawan ◽  
Hairudi Hairudi

COVID-19 pandemic has become a global issues, especially involving cardiovascular diseases. The management of COVID-19 patients with ST-Segment elevation in early pandemic era faces new challenges. Challenges can occur in term of patient’s delay and healthcare safety. This case series discussed clinical manifestations, examination findings, alternative strategies including thrombolytic and conservative therapy, and patients’ outcomes.

2021 ◽  
Vol 14 (10) ◽  
pp. e245566
Author(s):  
Ahmed Gargoum ◽  
Idris Bare ◽  
Christopher Pekrul ◽  
Shravan Nosib

We present the case of a previously healthy 25-year-old woman who presented with an out-of-hospital ventricular fibrillation arrest. Postresuscitation ECG did not show any evidence of ST segment elevation. Echocardiogram showed regional wall abnormalities in keeping with takotsubo syndrome (TTS). Urgent coronary angiogram to rule out malignant congenital coronary artery anomaly revealed an isolated severe ostial left main coronary artery (LMCA) stenosis, a rare disease, approximately 0.2% in previous case series. The LMCA was aneurysmal. Genetic studies revealed a novel frameshift pathogenic variant in the transforming growth factor B two ligand gene (TGFB2) gene, suggestive of Loeys-Dietz syndrome (LDS) type 4, an aggressive vascular disease. Ostial LMCA stenosis has not been previously reported in LDS, and we outline the management of this unique disease combination. We also reflect on its presentation as TTS and infer that TTS and acute coronary syndromes are not mutually exclusive.


Aorta ◽  
2021 ◽  
Vol 09 (05) ◽  
pp. 184-185
Author(s):  
Azhar Hussain ◽  
Alessia Rossi ◽  
Alexander Smith ◽  
Ana Lopez-Marco ◽  
Amina Khalil ◽  
...  

AbstractType A aortic dissection is a life-threatening condition with a wide range of clinical manifestations. Dissection can sometimes mimic an acute myocardial infarction due to similar presenting symptoms and initial clinical investigations. We report the case of a 52-year-old male who presented with an inferior ST-segment elevation myocardial infarction with two drug-eluting stents inserted as a stabilizing intervention prior to surgical repair of an acute aortic dissection.


Author(s):  
Khalid A S Abdalla ◽  
Antonio Sorgente ◽  
Pedro Brugada

Abstract Background ST-segment deviation post-electrical cardioversion is a common finding amongst a significant number of patients. However, the mechanism by which this phenomenon occurs and its clinical implications are not fully understood. Case summary Four patients presented to our department with complaints of palpitations. They were found to have atrial fibrillation and were cardioverted using a synchronized direct current shock at 200 J. However, their telemetry immediately after the shock showed transiently an ST-segment elevation resembling Brugada Type 1 pattern. All telemetries normalized within 6 s from cardioversion. Discussion Through this report, we aim to raise mild concern about a possible safety issue related to synchronized electrical cardioversion with electrodes positioned in an anteroposterior fashion. Also, we try to give a pathophysiological explanation to this finding on the base of the knowledge accumulated through the years on Brugada syndrome.


2011 ◽  
Vol 19 (5) ◽  
pp. 1080-1087 ◽  
Author(s):  
Viviane de Araújo Gouveia ◽  
Edgar Guimarães Victor ◽  
Sandro Gonçalves de Lima

This case series aimed to evaluate the behavior adopted by patients during the pre-hospital phase of acute myocardial infarction (AMI). A total of 115 AMI sufferers with ST-segment elevation were evaluated. The chi-square and Fisher's exact tests were applied. The individuals that did not associate the symptoms with cardiovascular disease most often attributed them to the following sources: gastrointestinal (38%), musculoskeletal (29.7%), food and/or medication poisoning (8.5%) and arising from the respiratory apparatus (6.3%). The proportion of major outcomes and of patients that arrived in the emergency department after 12 hours was higher among women, individuals with monthly income of up to one minimum wage, those who used analgesics and did not associate the symptoms with cardiovascular disease. It was found that individuals in unfavorable socioeconomic conditions, who interpreted the symptoms incorrectly, arrived later at the emergency department and had worse intra-hospital outcomes.


2021 ◽  
Vol 5 (2) ◽  
Author(s):  
Mehrdad Saririan ◽  
Richard Armstrong ◽  
Jon C George ◽  
Bartosz Olechowski ◽  
Stephen O’Connor ◽  
...  

Abstract Background  The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the pathogen responsible for the now pandemic disease, coronavirus disease (COVID-19). A number of reports have emerged suggesting these patients may present with signs and symptoms consistent with ST-segment elevation myocardial infarction without coronary artery occlusion. Case summary  We report an international case series of patients with confirmed COVID-19 infection who presented with suspected ST-segment elevation myocardial infarction. Three patients with confirmed COVID-19 presented with electrocardiogram criteria for ST-segment elevation myocardial infarction. No patient had obstructive coronary disease at coronary angiography. Post-mortem histology in one case demonstrated myocardial ischaemia in the absence of coronary atherothrombosis or myocarditis. Discussion  Patients with COVID-19 may present with features consistent with ST-segment elevation myocardial infarction and patent coronary arteries. The prevalence and clinical outcomes of this condition require systematic investigation in consecutive unselected patients.


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