scholarly journals Controlling Systemic Inflammation by Careful Formulation of Topical Skin Care Products: Our Bodies Didn’t Evolve With All the Current Chemicals in Skin Care Products

Author(s):  
Greg Maguire

Although man is still rapidly evolving, he has not co-evolved with all of the modern chemicals made by man, including those in cosmetic products. Care must be taken when formulating products so that commonly used ingredients, such as polyethylene glycol, can be substituted with safer ingredients to which man has adapted and that will not cause irritation and inflammation. This is especially important given that induction of skin inflammation will cause systemic inflammation. A review of the literature and of commercially available products was made to highlight techniques and products that remediate inflammation or induce inflammation. Many skin care products contain chemicals that induce irritation and inflammation that may lead to chronic, systemic inflammation. Well studied natural products, especially skin identical chemicals, may offer an advantage compared to recent man-made chemicals in cosmetic and topical formulations and help to reduce skin inflammation as well as skin derived systemic chronic inflammation.

2019 ◽  
Author(s):  
Kristiana Etnawati ◽  
Dwi Retno Adiwinarni ◽  
Devi Artami Susetiati ◽  
Yusuke Sauchi ◽  
Hitomi Ito

Glutathione is a potent antioxidant, which is widely used in skin care products for skin lightening especially in the Asian market. Presently, there was only one study of topical 2% oxidized glutathione (GSSG) in Philipino women, further study is needed to evaluate the efficacy and safety of cosmetic products containing glutathione. A double blind randomized clinical trial study was conducted in Yogyakarta, Indonesia, in 74 healthy Indonesian women, with average age 33.3 ± 5.9 years when subjects participated in the study. Each subject received supervised applications of Facial Wash twice a day, Day Cream with sunscreen and Night Cream. The subjects were divided into 3 groups based on the active ingredients of the tested products, which included glutathione reduced (GSH) 0.1%, GSH 0.5%, and without GSH. The effects of the tested products in lightening skin color and pigmentation were measured colorimetry with Chromameter Minolta for L*. Compared to a baseline, there were significant increases of L* (lightness) or ΔL* detected as early as week 2 in which group of GSH 0.1% were significantly higher compared to group of GSH 0.5% and group without GSH. Hyperpigmented lesions also improved, where GSH 0.5% group showed its superiority compared to others groups in week 8. The undesired effect were few minutes mild tingling sensation after night cream, and worsening of acne in all tested products. Conclusion skin care products containing GSH 0.1% and 0.5% were effective in facial skin lightening.


2019 ◽  
Vol 102 (4) ◽  
pp. 287-303 ◽  
Author(s):  
Jack M. Woolley ◽  
Vasilios G. Stavros

Mycosporine-like amino acids have long been known as a natural form of photoprotection for fungi and cyanobacteria. This review will highlight the key time-resolved experimental and theoretical techniques unravelling their photochemistry and photophysics, and directly link this to their use in commercial skin-care products, namely as sunscreen filters. Three case studies have been selected, each having aided advancement in this burgeoning field of research. We discuss these studies in the context of photoprotection and conclude by evaluating the necessary future steps towards translating the photochemistry and photophysics insight of these nature derived sunscreen filters to commercial application.


2018 ◽  
Vol 10 (5) ◽  
pp. 13 ◽  
Author(s):  
Nasrul Wathoni ◽  
Ani Haerani ◽  
Nia Yuniarsih ◽  
Retno Haryanti

Nowadays, Herbal cosmetic is growing rapidly as most women prefer natural products rather than chemicals products for their personal care. Herbal cosmetic contains natural nutrients to improve and provide consumers satisfaction due to relatively fewer side effects compared to synthetic cosmetics. Indonesia is one of the biggest supplier’s countries for herbal raw materials in cosmetic products. Many plants are available naturally as well as different uses that can be made as basic ingredients for cosmetic preparations, such as onion dayak bulb, kemuning leaf, pegagan, kecombrang, red betel, pecan, and sweet root. This review aimed to provide information on plants in Indonesia based on the phytochemicals contents that can be formulated into various categories of cosmetic preparations, such as skin care, hair care, anti-aging, skin whitening, and antioxidant.


2016 ◽  
Vol 74 (1) ◽  
Author(s):  
Boel Aniansson ◽  
Marit B. Veierød ◽  
Charlotta Rylander ◽  
Eiliv Lund ◽  
Torkjel M. Sandanger

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