scholarly journals Visceral adiposity indicators and cardiovascular risk in hemodialytic patients

2021 ◽  
Author(s):  
Dejane de Almeida Melo ◽  
Alcione Miranda dos Santos ◽  
Elane Viana Hortegal Furtado ◽  
Ana Karina Teixeira França ◽  
Elisângela Milhomem dos Santos ◽  
...  
Keyword(s):  
Cardiovascular Risk ◽  
Visceral Adiposity

Abstract P363: Visceral, but Not Subcutaneous Adiposity by Computed Tomography is Associated With Increased Aortic Wall Thickness in Psoriasis Patients

Circulation ◽  
2018 ◽  
Vol 137 (suppl_1) ◽  
Author(s):  
Jacob W Groenendyk ◽  
Parag Shukla ◽  
Youssef A Elnabawi ◽  
Joshua P Rivers ◽  
Aditya Goyal ◽  
...  
Keyword(s):  
Cardiovascular Risk ◽  
Wall Thickness ◽  
Aortic Wall ◽  
Subclinical Atherosclerosis ◽  
Visceral Adiposity ◽  
Framingham Risk ◽  
High Prevalence ◽  
Multivariable Regression ◽  
Aortic Wall Thickness ◽  
Subcutaneous Adiposity

Introduction: Patients with psoriasis (PSO), an inflammatory skin disease, experience increased cardiovascular disease and obesity. Traditional measures of obesity, such as BMI and waist-to-hip ratio (WHR), do not fully capture the increased cardiovascular risk. Assessment of adipose tissue distribution via CT scan enables characterization of visceral adiposity (VAT) versus subcutaneous adiposity (SAT), which is clinically useful as excess VAT is known to be associated with cardiovascular events. Aortic Wall Thickness (AWT) is a validated measure of subclinical atherosclerosis. However, the relationship between adiposity distribution and AWT is unknown. Hypothesis: We hypothesized that VAT, but not SAT, BMI, or WHR, would be associated with increased AWT in PSO patients. Methods: Consecutive PSO patients (n=164) underwent quantification of VAT and SAT via CT, and AWT via MRI of the descending aorta. Interrelationships were analyzed via multivariable regression. Results: Patients were middle-aged (mean 50.4), predominantly male (56%), and were at low cardiovascular risk (median Framingham risk 3), despite high prevalence of hyperlipidemia (47%). VAT was significantly associated with AWT (β=0.18, p=0.04), SAT, BMI, or WHR did not demonstrate similar association. This association persisted beyond adjustment for SAT, Framingham score, insulin resistance, and systolic BP (β=0.30, p=0.03). Conclusions: Visceral adiposity demonstrated an association with AWT, a marker of early atherosclerosis, whereas subcutaneous adiposity, BMI, and WHR did not. These findings add to a growing body of literature that visceral fat and its assessment may provide incremental data for risk of subclinical CVD.

scholarly journals VISCERAL ADIPOSITY AS A GLOBAL FACTOR OF CARDIOVASCULAR RISK

2018 ◽  
pp. 7-14 ◽  
Author(s):  
G. A. Chumakova ◽  
T. Yu. Kuznetsova ◽  
M. A. Druzhilov ◽  
N. G. Veselovskaya
Keyword(s):  
Cardiovascular Risk ◽  
Visceral Adiposity ◽  
Global Factor

Adiposity Indexes as Phenotype-Specific Markers of Preclinical Metabolic Alterations and Cardiovascular Risk in Polycystic Ovary Syndrome: A Cross-Sectional Study

2017 ◽  
Vol 125 (05) ◽  
pp. 307-315 ◽  
Author(s):  
Fernanda Mario ◽  
Scheila Graff ◽  
Poli Spritzer
Keyword(s):  
Cardiovascular Risk ◽  
Polycystic Ovary Syndrome ◽  
Lipid Accumulation ◽  
Polycystic Ovary ◽  
Visceral Adiposity ◽  
Visceral Adiposity Index ◽  
Lipid Accumulation Product ◽  
Ovary Syndrome ◽  
Metabolic Alterations ◽  
Adiposity Index

AbstractPolycystic ovary syndrome (PCOS) is a common condition in women of reproductive age. 2 PCOS phenotypes (classic and ovulatory) are currently recognized as the most prevalent, with important differences in terms of cardiometabolic features. We studied the performance of different adiposity indexes to predict preclinical metabolic alterations and cardiovascular risk in 234 women with PCOS (173 with classic and 61 with ovulatory PCOS) and 129 controls. Performance of waist circumference, waist-to-height ratio, conicity index, lipid accumulation product, and visceral adiposity index was assessed based on HOMA-IR ≥ 3.8 as reference standard for screening preclinical metabolic alterations and cardiovascular risk factors in each group. Lipid accumulation product had the best accuracy for classic PCOS, and visceral adiposity index had the best accuracy for ovulatory PCOS. By applying the cutoff point of lipid accumulation product<34, we identified a subgroup of patients without cardiometabolic alterations (P<0.05) in the group with classic PCOS, a population at higher risk for hypertension, dyslipidemia, and impaired glucose tolerance. In ovulatory PCOS, visceral adiposity index ≥ 1.32 was capable of detecting women with significantly higher blood pressure and less favorable glycemic and lipid variables as compared to ovulatory PCOS with lower visceral adiposity index (P<0.05). These results suggest LAP ≥ 34 as the best marker for classic PCOS, and VAI ≥ 1.32 for ovulatory PCOS women. Both indexes can be easily calculated with measures obtained in routine clinical practice and may be useful to detect cardiometabolic risk and secure early interventions.

PO21-653 WHICH PARAMETER IN RELATION OF VISCERAL ADIPOSITY SHOULD BE EVALUATED AS A CARDIOVASCULAR RISK FACTOR?

2007 ◽  
Vol 8 (1) ◽  
pp. 176
Author(s):  
L.E. Sade ◽  
S. Eroglu ◽  
H. Bozbas ◽  
A.S. Ozgul ◽  
A. Yildirir ◽  
...  
Keyword(s):  
Risk Factor ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factor ◽  
Visceral Adiposity

scholarly journals Visceral obesity and cardiometabolic risk: features of hormonal and immune regulation

2017 ◽  
Vol 14 (3) ◽  
pp. 3-10 ◽  
Author(s):  
Irina V. Kologrivova ◽  
Irina V. Vinnitskaya ◽  
Olga A. Koshelskaya ◽  
Tatiana E. Suslova
Keyword(s):  
Adipose Tissue ◽  
Cardiovascular Risk ◽  
Immune Regulation ◽  
Subcutaneous Adipose Tissue ◽  
Energy Homeostasis ◽  
Cardiometabolic Risk ◽  
Visceral Obesity ◽  
Epidemiological Studies ◽  
Visceral Adiposity ◽  
Subcutaneous Adipose

The issue of the prognostic value of obesity in the development of cardiovascular diseases still remains open. Different input of visceral and subcutaneous adipose tissue in the formation of cardiometabolic risk is highlighted in many research works. A range of epidemiological studies provides data confirming relation of the visceral adiposity with abnormal metabolic profile and increased cardiovascular risk, while subcutaneous adipose tissue is attributed with relative protective properties. Pathophysiological mechanisms mediating interconnection of visceral adiposity with the development of atherosclerosis remain studied incompletely. It was stated that sex hormones, estrogens and androgens, participate in the redistribution of adipose tissue, sustenance of energy homeostasis, influence on the secretion of adipokines and immune regulation of adipose tissue. Meanwhile cells of immune system, including cells of the adaptive immunity, widely presented in adipose tissue contribute to the development of the local subclinical inflammation and influence on the features of cardiometabolic effects of adipose tissue. The review discusses possible mechanisms, by which abovementioned relationships are executed and cardiovascular risk in obesity is realized.

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