scholarly journals A narrative review of individualized treatments of genitourinary tumors: is the future brighter with molecular evaluations?

2021 ◽  
Vol 10 (3) ◽  
pp. 1553-1561
Author(s):  
Francesca Giunchi ◽  
Tania Franceschini ◽  
Michelangelo Fiorentino
2020 ◽  
Vol 2020 ◽  
pp. 1-8 ◽  
Author(s):  
Alexandru Burlacu ◽  
Adrian Covic ◽  
Mircea Cinteza ◽  
Paula Madalina Lupu ◽  
Radu Deac ◽  
...  

Introduction. Including healthcare professionals dealing with cardiovascular diseases, Heart Team is a concept/structure designed for selecting diagnostic strategies, facilitating therapeutic decisions, and improving cardiovascular outcomes in patients with complex heart pathologies, requiring input from different subspecialties and the necessity of a multidisciplinary approach. The aim of this narrative review is to search for and to summarize current evidence regarding Heart Team and to underline the future directions for the development of this concept. Methods. We searched the electronic database of PubMed, SCOPUS, and Cochrane CENTRAL for studies including Heart Team. Forty-eight studies were included, if reference was made to Heart Team structure and functionality. Results. We depicted the structure and the timeline of Heart Team, along with actual evidence-based recommendations from European Guidelines. We underlined the importance of quality of knowledge-sharing and decision-making inside the Team, analyzing bad decisions which did not reflect members’ true beliefs due to “uniformity pressure, closed mindedness, and illusion of invulnerability.” The observation that Guidelines’ indications regarding Heart Team carry a level C indication underlines the very future of this Team: randomized controlled trials proving solid benefits in an evidence-based world. Conclusions. Envisioned as a tool for optimizing the management of various complex cardiovascular pathologies, Heart Team should simplify and facilitate the activity in the cardiovascular ward. Finally, these facts should be translated into better cardiovascular outcomes and a lower psychological distress among Team participants. Despite all future changes, there must always be a constant part: the patient should remain at the very center of the Team.


Dental Update ◽  
2020 ◽  
Vol 47 (5) ◽  
pp. 421-432 ◽  
Author(s):  
Maurice J Meade ◽  
Declan T Millett

Indefinite retention is now considered essential to prevent relapse after orthodontic treatment. Compliance with removable retainer wear is suboptimal and appears to decline with time post-treatment. As a result, use of bonded retainers may become more commonplace in the future. In this narrative review, the characteristics of bonded retainers are outlined and a summary of the evidence from randomized clinical trials regarding their effectiveness is provided. Guidance is also offered regarding care and maintenance. CPD/Clinical Relevance: All general dental practitioners (GDPs) should be familiar with types of bonded retainers, evidence relating to their effectiveness and the GDP's role regarding their care and maintenance.


2016 ◽  
Vol 70 (5) ◽  
pp. 799-805 ◽  
Author(s):  
Christopher R. Chapple ◽  
Con J. Kelleher ◽  
Chris J. Evans ◽  
Zoe Kopp ◽  
Emad Siddiqui ◽  
...  

2015 ◽  
Vol 11 (2) ◽  
pp. 516-521 ◽  
Author(s):  
Haiyu Zhang ◽  
Tingting Ge ◽  
Xiaoming Cui ◽  
Yan Hou ◽  
Chaofu Ke ◽  
...  

Plasma metabolic profiling yielded a panel of prognostic biomarkers, which strongly predicted ovarian cancer recurrence and could potentially shape individualized treatments in the future.


2021 ◽  
Author(s):  
Paul Longley Arthur ◽  
Lydia Hearn

Abstract Open research represents a new set of principles and methodologies for greater cooperation, transparent sharing of findings, and access to and re-use of research data, materials or outputs, making knowledge more freely available to wider audiences for societal benefit. Yet, the future success of the international move toward open research will be dependent on key stakeholders addressing current barriers to increase uptake, effectiveness, and sustainability. This article builds on “An Agenda for Open Science in Communication,” raising dialog around the need for a broader view of open research as opposed to open science through a deeper understanding of specific challenges faced by the humanities. It reviews how the multifaceted nature of humanities research outputs make open communication formats more complex and costly. While new avenues are emerging to advance open research, there is a need for more collaborative, coordinated efforts to better connect humanities scholars with the communities they serve.


2021 ◽  
Vol 0 ◽  
pp. 0-0
Author(s):  
Daniele Castellani ◽  
◽  
Rodrigo Donalisio da Silva ◽  
Marcela Pelayo-Nieto ◽  
Edgar Linden-Castro ◽  
...  
Keyword(s):  
The Past ◽  

2016 ◽  
Vol 16 (1) ◽  
pp. 29-43 ◽  
Author(s):  
Andrew Clark ◽  
Lisa Morriss

This paper outlines the use of visual methodologies in international social work research over the past 10 years. It presents a narrative overview of the types and range of visual methodologies that have been used, explores the benefits of employing visual methodologies in social work research and outlines some considerations for researchers thinking of working with the visual. The review is not intended to be an exhaustive overview of the field but rather highlights important issues and concerns when using visual methodologies. A deeper, reflexive engagement with the complexities (practical as well as methodological and epistemic) of undertaking visual research is required and engaging in the issues we raise will enable social work research to make valuable contributions to the wider field of visual researching.


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