scholarly journals Comparison of cross-sectional imaging techniques for the detection of prostate cancer lymph node metastasis: a critical review

2020 ◽  
Vol 9 (3) ◽  
pp. 1415-1427
Author(s):  
Amir H. Lebastchi ◽  
Nikhil Gupta ◽  
John M. DiBianco ◽  
Morand Piert ◽  
Matthew S. Davenport ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Critical Review ◽  
Imaging Techniques ◽  
Cross Sectional ◽  
Node Metastasis ◽  
Cross Sectional Imaging ◽  
Sectional Imaging

The role of pre-biopsy mpMRI in lymph node staging for prostate cancer

2021 ◽  
pp. 039156032110168
Author(s):  
Nassib Abou Heidar ◽  
Robert El-Doueihi ◽  
Ali Merhe ◽  
Paul Ramia ◽  
Gerges Bustros ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Lymph Node ◽  
High Risk ◽  
Gleason Score ◽  
Gold Standard ◽  
Cross Sectional ◽  
Significant Difference ◽  
Cross Sectional Imaging ◽  
Sectional Imaging ◽  
Kappa Agreement

Introduction: Prostate cancer (PCa) staging is an integral part in the management of prostate cancer. The gold standard for diagnosing lymph node invasion is a surgical lymphadenectomy, with no superior imaging modality available at the clinician’s disposal. Our aim in this study is to identify if a pre-biopsy multiparametric MRI (mpMRI) can provide enough information about pelvic lymph nodes in intermediate and high risk PCa patients, and whether it can substitute further cross sectional imaging (CSI) modalities of the abdomen and pelvis in these risk categories. Methods: Patients with intermediate and high risk prostate cancer were collected between January 2015 and June 2019, while excluding patients who did not undergo a pre-biopsy mpMRI or a CSI. Date regarding biopsy result, PSA, MRI results, CSI imaging results were collected. Using Statistical Package for the Social Sciences (SPSS) version 24.0, statistical analysis was conducted using the Cohen’s Kappa agreement for comparison of mpMRI with CSI. McNemar’s test and receiver operator curve (ROC) curve were used for comparison of sensitivity of both tests when comparing to the gold standard of lymphadenectomy. Results: A total of 143 patients fit the inclusion criteria. We further stratified our patients into according to PSA level and Gleason score. Overall, agreement between mpMRI and all CSI was 0.857. When stratifying patients based on Gleason score and PSA, the higher the grade or PSA, the higher agreement between mpMRI and CSI. The sensitivity of mpMRI (73.7%) is similar to CSI (68.4%). When comparing CSI sensitivity to that of mpMRI, no significant difference was present by utilizing the McNemar test and very similar receiver operating characteristic curve. Conclusion: A pre-biopsy mpMRI can potentially substitute further cross sectional imaging in our cohort of patients. However, larger prospective studies are needed to confirm our findings.

Prostate Cancer Lymph Node Metastasis

2009 ◽  
Vol 2 (1) ◽  
pp. 16-31
Author(s):  
Sanja Coso ◽  
Elizabeth D. Williams
Keyword(s):  
Prostate Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Node Metastasis

UP-02.167 Prostate Cancer Tumour Volumes and Lymph Node Metastasis: Do We Need MRI?

Urology ◽  
2011 ◽  
Vol 78 (3) ◽  
pp. S318
Author(s):  
S. Robinson ◽  
O. Karim ◽  
M. Laniado ◽  
H. Motiwala
Keyword(s):  
Prostate Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Node Metastasis

scholarly journals Grading, staging and Nottingham prognostic index scoring of breast carcinoma

2017 ◽  
Vol 7 (1) ◽  
pp. 1078-1083
Author(s):  
A Pradhan ◽  
P Paudyal ◽  
AK Sinha ◽  
CS Agrawal
Keyword(s):  
Lymph Node ◽  
Breast Carcinoma ◽  
Lymph Node Metastasis ◽  
Prognostic Index ◽  
Nottingham Prognostic Index ◽  
Eastern Region ◽  
Axillary Lymph ◽  
Cross Sectional ◽  
Tnm System ◽  
Node Metastasis

Background: Breast carcinoma is the most frequent malignant tumor in women accounting for approximately 15% of female cancer deaths. It is the second most common malignancy among women in Nepal. Our objectives were to study the extent and spread of different histological types breast carcinoma in the eastern region of Nepal, to grade and stage the tumors, score the prognosis.Materials and Methods: A cross-sectional descriptive study of mastectomy specimens with axillary lymph node sampling was done for a period of two years. Diagnosis was done using WHO classification. Modified Bloom Richardson score and TNM system was used to grade and stage the tumors. Nottingham Prognostic index was applied to score the prognosis.Results: Out of 31 total cases, the most common histologic type was Invasive Carcinoma of No Special Type (67.74%). The largest tumor size was of 12cm which had poor NPI score. Most tumors were of grade II and T2. Out of 30 cases with lymph nodes, 13 were negative for metastasis pN0, 10 were pN1 and 7 were pN2. Extranodal spread was observed in 6 out of 17 cases with lymph node metastasis and was associated with higher grades and poor prognosis.Conclusion: Higher grade tumors, lymph node metastasis and extranodal extension are associated with higher Nottingham Prognostic Index score. 

scholarly journals Abdominal manifestations of extranodal lymphoma: pictorial essay

2016 ◽  
Vol 49 (6) ◽  
pp. 397-402 ◽  
Author(s):  
Laís Fajardo ◽  
Guilherme de Araujo Ramin ◽  
Thiago José Penachim ◽  
Daniel Lahan Martins ◽  
Patrícia Prando Cardia ◽  
...  
Keyword(s):  
Diagnostic Imaging ◽  
Clinical Setting ◽  
Imaging Techniques ◽  
Extranodal Lymphoma ◽  
Cross Sectional ◽  
Appropriate Treatment ◽  
Pictorial Essay ◽  
Cross Sectional Imaging ◽  
Sectional Imaging

Abstract In the appropriate clinical setting, certain aspects of extranodal abdominal lymphoma, as revealed by current cross-sectional imaging techniques, should be considered potentially diagnostic and can hasten the diagnosis. In addition, diagnostic imaging in the context of biopsy-proven lymphoma can accurately stage the disease for its appropriate treatment. The purpose of this article was to illustrate the various imaging aspects of extranodal lymphoma in the abdomen.

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