We are on the right road | A brief history of breast cancer guidelines in China

Cancer metastasis to the oral and maxillofacial region is uncommon, and metastasis to the mandibular condyle is considered rare. We present a case of a 56-year-old woman with a history of invasive ductal cell carcinoma of the right breast, 10 years in remission, presenting with a 6-month history of symptoms typical of temporomandibular joint (TMJ) dysfunction. Imaging revealed an osteolytic lesion of her right TMJ and subsequent open biopsy confirmed the diagnosis of metastatic breast cancer. Despite the rarity of metastatic cancer to the head and neck region, it is still important for clinicians from both medical and dental backgrounds to consider this differential diagnosis, particularly in patients with a history of hormonal positive subtype of breast cancer. Given that bony metastasis can manifest even 10 years after initial diagnosis, surveillance which includes examination of the head and neck region is important, and may include routine plain-film imaging surveillance with an orthopantomogram (OPG).

Download Full-text

A Synchronous Diagnosis of Metastatic Male Breast Cancer and Prostate Cancer

Journal of Investigative Medicine High Impact Case Reports ◽

10.1177/2324709619847230 ◽

2019 ◽

Vol 7 ◽

pp. 232470961984723

Author(s):

Leila Moosavi ◽

Phyllis Kim ◽

An Uche ◽

Everardo Cobos

Keyword(s):

Breast Cancer ◽

Prostate Cancer ◽

Male Breast Cancer ◽

Breast Cancer Diagnosis ◽

Male Breast ◽

Breast Mass ◽

Medical Attention ◽

Cancer History ◽

History Of ◽

The Right

In this article, we present a patient diagnosed synchronously with metastatic male breast cancer and prostate cancer. This is a 63-year-old male and recent immigrant from Nigeria, who sought medical attention for progressively worsening of shortness of breath and acute progression of a chronic right breast mass. An invasive breast carcinoma was diagnosed by the core biopsy of the right breast mass. Within 2 months of his breast cancer diagnosis, the patient also was diagnosed with prostate adenocarcinoma after being worked up for urinary retention. By presenting this patient with a synchronous diagnosis with metastatic male breast cancer and prostate cancer, history of chronic right breast mass, and gynecomastia, we speculate on possible cancer etiologies and risk factors.

Download Full-text

Women with History of Breast Cancer Excluded from Screening Programs: Is It the Right Choice?

Radiology ◽

10.1148/radiol.2343041588 ◽

2005 ◽

Vol 234 (3) ◽

pp. 971-972 ◽

Cited By ~ 6

Author(s):

Francesco Sardanelli ◽

Franca Podo

Keyword(s):

Breast Cancer ◽

Screening Programs ◽

History Of ◽

The Right

Download Full-text

The Right to Be Covered

10.1093/oso/9780190612757.003.0011 ◽

2021 ◽

pp. 257-282

Author(s):

Lewis A. Grossman

Keyword(s):

Breast Cancer ◽

Health Care ◽

Insurance Coverage ◽

Therapeutic Choice ◽

History Of ◽

Patient Groups ◽

The Right

This chapter explores the paradoxical assertion of freedom of therapeutic choice in the context of reimbursed health care. Cries of “rationing!” and “death panel!” are directed at every suggestion of a limitation on government insurance coverage. This chapter traces the history of the notion of a “right to be reimbursed” for one’s therapeutic choices since the 1930s. It explores the persistent public insistence on “a right to choose one’s doctor” in insurance plans. It describes the history of drug formularies and patients’ resistance to them. The chapter focuses most intensively on the controversy surrounding the FDA’s November 2011 withdrawal of provisional approval of Avastin for the treatment of breast cancer. Conservatives and patient groups used the language of rights to attack this decision even though it did not remove the drug from the market; the protesters’ real fear was that insurance plans would stop reimbursing patients for this use.

Download Full-text

Carcinoma en cuirasse associated to zosteriform metastasis from breast adenocarcinoma

Cancer Research and Cellular Therapeutics ◽

10.31579/2640-1053/087 ◽

2021 ◽

Vol 5 (4) ◽

pp. 01-03

Author(s):

Refka Frioui ◽

Azza Ghannem ◽

Mariam Tabka ◽

Badreddine Sriha ◽

Colandane Belajouza ◽

...

Keyword(s):

Breast Cancer ◽

Ductal Carcinoma ◽

Clinical Manifestations ◽

Left Breast ◽

Metastatic Carcinoma ◽

Breast Adenocarcinoma ◽

Wide Range ◽

History Of ◽

Original Case ◽

The Right

We report an original case of carcinoma en cuirasse associated with zosteriform metastasis. A 40-year-old woman presented to our department with painful erythematous lesions. She had a history of invasive ductal carcinoma of the left breast. Numerous erythematous, papules and whitish vesicles were present over the right side of the chest in a dermatomal distribution with indurated coalescent plaques. Biopsy revealed metastatic carcinoma of breast origin. Breast mammography showed suspicious right nodule. Controlateral breast carcinoma with CM was diagnosed. CM show a wide range of clinical manifestations. Carcinoma en cuirasse, is a very rare form of metastatic cutaneous breast cancer. It is characterized by diffuse sclerodermatous induration of the skin. Zosteriform metastasis is also rarely seen. It may be distributed along dermatomeres in a variety of clinical patterns, including nodular, papulovesicular, or vesiculobullous. In our case, the zosteriform metastasis occurred in the contralateral site. It announced the developing of contralateral breast cancer.

Download Full-text

Surgical treatment for breast cancer in a patient with erythropoietic protoporphyria and photosensitivity: a case report

Surgical Case Reports ◽

10.1186/s40792-020-01068-5 ◽

2021 ◽

Vol 7 (1) ◽

Author(s):

Akiko Shimazaki ◽

Takuma Hashimoto ◽

Masaya Kai ◽

Tetsuzo Nakayama ◽

Mai Yamada ◽

...

Keyword(s):

Breast Cancer ◽

Rare Condition ◽

Perioperative Period ◽

Polyimide Film ◽

Lymph Node Biopsy ◽

Erythropoietic Protoporphyria ◽

Case Presentation ◽

History Of ◽

Close Cooperation ◽

The Right

Abstract Background Erythropoietic protoporphyria (EPP) is a rare disorder of heme synthesis. Patients with EPP mainly show symptoms of photosensitivity, but approximately 20% of EPPs are associated with the liver-related complications. We report a case of breast cancer in a 48-year-old female patient with EPP in whom meticulous perioperative management was required in order to avoid complications resulting from this disease. Case presentation The patient was diagnosed with EPP at the age of 33 and had a rich family history of the disease. For right breast cancer initially considered as TisN0M0 (Stage 0), the right mastectomy and sentinel lymph node biopsy were performed, while the final stage was pT1bN0M0, pStage I. In the perioperative period, we limited the drug use and monitored light wavelength measurements. Besides, we covered surgical lights, headlights, and laryngoscope’s light with a special polyimide film that filtered the wavelength of light causing dermal photosensitivity. After the surgery, any emerging complications were closely monitored. Conclusions The surgery, internal medicine, anesthesiology, and operation departments undertook all possible measures through close cooperation to ensure a safe surgery for the patient with a rare condition.

Download Full-text

A novel case of Silver Russell Syndrome (SRS) and male breast cancer

Journal of Clinical Oncology ◽

10.1200/jco.2007.25.18_suppl.21178 ◽

2007 ◽

Vol 25 (18_suppl) ◽

pp. 21178-21178

Author(s):

C. M. Hamm ◽

L. Jagiello

Keyword(s):

Breast Cancer ◽

Brca2 Gene ◽

Metastatic Breast ◽

Brca1 Gene ◽

Abdominal Ultrasound ◽

Significant Family History ◽

History Of ◽

Asymmetric Growth ◽

The Right ◽

The Relationship

21178 Introduction: Silver Russell Syndome (SRS) is a heterogeneous disorder of asymmetric growth retardation and typical dysmorphic features often associated with maternal disomy 7 and chromosome 17q23–24. The BRCA1 gene is found on 17q21. The relationship between SRS and breast cancer has not been described to date. Case Presentation: We report a case of a 37 year old male diagnosed with metastatic breast cancer involving the liver and bone. Patient presented with a left proximal hip fracture related to metastatic bone disease. Biopsy of the right breast lesion revealed a moderately differentiated adenocarcinoma consistent with breast primary. Abdominal ultrasound and full body bone scan revealed extensive liver and bone metastases. There was no significant family history of cancer, specifically breast nor ovarian cancer. Discussion: The BRCA2 gene is known to be responsible for DNA repair. The SRS cases associated with chromosome 17q24–25 abnormalities are known to be associated with growth hormone deletions. Further investigations into this relationship are warranted. No significant financial relationships to disclose.

Download Full-text

Metastasis to Internal Mammary Node

Mayo Clinic Challenging Images for Pulmonary Board Review ◽

10.1093/med/9780199756926.003.0086 ◽

2010 ◽

pp. 644-647

Author(s):

Edward C. Rosenow

Keyword(s):

Breast Cancer ◽

Left Lung ◽

Internal Mammary Node ◽

White Arrow ◽

Internal Mammary ◽

History Of ◽

The Right ◽

Yellow Arrow

• 56-year-old patient with a history of breast cancer • Confluence of shadows (white arrow) looks like a lesion in left lung, but it is not seen on CT (next slide). The lesion on the lateral CXR is in the right lung (yellow arrow) •...

Download Full-text

Z-line degradation and phagocytosis of sarcomeric fragments in myonecrosis

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100077529 ◽

1983 ◽

Vol 41 ◽

pp. 790-791

Author(s):

Melinda L. Estes ◽

Samuel M. Chou

Keyword(s):

Vastus Lateralis ◽

Inflammatory Myopathy ◽

Muscle Disease ◽

White Female ◽

Inflammatory Cell Infiltrate ◽

Limb Weakness ◽

Muscle Diseases ◽

History Of ◽

The Right ◽

Mononuclear Inflammatory Cell

Many muscle diseases show common pathological features although their etiology is different. In primary muscle diseases a characteristic finding is myofiber necrosis. The mechanism of myonecrosis is unknown. Polymyositis is a primary muscle disease characterized by acute and subacute degeneration as well as regeneration of muscle fibers coupled with an inflammatory infiltrate. We present a case of polymyositis with unusual ultrastructural features indicative of the basic pathogenetic process involved in myonecrosis.The patient is a 63-year-old white female with a one history of proximal limb weakness, weight loss and fatigue. Examination revealed mild proximal weakness and diminished deep tendon reflexes. Her creatine kinase was 1800 mU/ml (normal < 140 mU/ml) and electromyography was consistent with an inflammatory myopathy which was verified by light microscopy on biopsy muscle. Ultrastructural study of necrotizing myofiber, from the right vastus lateralis, showed: (1) degradation of the Z-lines with preservation of the adjacent Abands including M-lines and H-bands, (Fig. 1), (2) fracture of the sarcomeres at the I-bands with disappearance of the Z-lines, (Fig. 2), (3) fragmented sarcomeres without I-bands, engulfed by invading phagocytes, (Fig. 3, a & b ), and (4) mononuclear inflammatory cell infiltrate in the endomysium.

Download Full-text

Popliteal artery thrombosis secondary to a tibial osteochondroma

VASA ◽

10.1024/0301-1526/a000101 ◽

2011 ◽

Vol 40 (3) ◽

pp. 251-255 ◽

Cited By ~ 4

Author(s):

Gruber-Szydlo ◽

Poreba ◽

Belowska-Bien ◽

Derkacz ◽

Badowski ◽

...

Keyword(s):

Case Report ◽

Magnetic Resonance Angiography ◽

Popliteal Artery ◽

Doppler Ultrasonography ◽

Histopathological Examination ◽

Previous History ◽

Plain Radiography ◽

Artery Thrombosis ◽

History Of ◽

The Right

Popliteal artery thrombosis may present as a complication of an osteochondroma located in the vicinity of the knee joint. This is a case report of a 26-year-old man with symptoms of the right lower extremity ischaemia without a previous history of vascular disease or trauma. Plain radiography, magnetic resonance angiography and Doppler ultrasonography documented the presence of an osteochondrous structure of the proximal tibial metaphysis, which displaced and compressed the popliteal artery, causing its occlusion due to intraluminal thrombosis..The patient was operated and histopathological examination confirmed the diagnosis of osteochondroma.

Download Full-text