scholarly journals Tumor Control and Quality of Life in Skin Cancer Patients With Extensive Multilayered Nasal Defects

2020 ◽  
Vol 13 (2) ◽  
pp. 164-172 ◽  
Author(s):  
Michaela Plath ◽  
Hannah M. Thielen ◽  
Ingo Baumann ◽  
Karim Zaoui ◽  
Philippe A. Federspil
Keyword(s):  
Quality Of Life ◽  
Skin Cancer ◽  
Short Form ◽  
Cancer Control ◽  
Outcome Evaluation ◽  
Tumor Control ◽  
Extended Defect ◽  
Ablative Surgery ◽  
Significant Difference

Objectives. The reconstruction after nasal skin cancer (NSC) resection is often practiced differently. The objective of this study is to evaluate the influence of patient-, tumor- and management-related factors on the role of surgery and choice of reconstruction.Methods. This was a monocentric retrospective study of patients who were diagnosed with a NSC (squamous cell or basal cell carcinoma) and suffered from an extended defect after ablative surgery between 2003 and 2013. Twenty-five patients were included. Tumors were staged using the Union for International Cancer Control (eighth edition) TNM classification for primary cutaneous skin cancer of the head and neck. Preferred treatment was surgery in all patients. Health-related quality of life (HRQoL) measurement was evaluated by one generic (36-Item Short Form Health Survey [SF-36]) and two organ-specific questionnaires (Rhinoplasty Outcome Evaluation [ROE] and Functional Rhinoplasty Outcome Inventory 17 [FROI-17]) after therapy. Survival data were estimated by the Kaplan-Meier method and statistical analysis was performed by log-rank, analysis of variance, Levene’s and t-tests. The median follow-up time was 2.1 years.Results. According to the Union for International Cancer Control classification, 13 of 25 tumors were staged as pT1 (52%), four as pT2 (16%), seven as pT3 (28%) and one as pT4a (4%). Seventy-two percent of patients (n=18) chose plastic reconstruction, and for the remaining 28% (n=7) of the patients opted for an implant-retained prosthesis. The overall survival was 69.5% after 5 years, the 5-year recurrence-free survival was 90.9% and the 5-year disease-specific survival was 100%. There was no significant difference in the HRQoL outcome between both rehabilitation methods.Conclusion. Surgery in NSC gives an excellent oncologic prognosis. Nasal reconstruction and prostheses are both very viable options depending on tumor stage and biology, the patient’s wishes as well as the experience of the surgeon.

Abstract TP295: Stroke Prevention Surgery > Quality of Life and Cognitive Ability to Drive Are Maintained After Surgical Repair of Unruptured Intracranial Aneurysm

Stroke ◽  
2020 ◽  
Vol 51 (Suppl_1) ◽  
Author(s):  
Joan M ODonnell ◽  
Maurizio Manuguerra ◽  
Jemma L Hodge ◽  
Greg Savage ◽  
Michael K Morgan
Keyword(s):  
Quality Of Life ◽  
Intracranial Aneurysm ◽  
Surgical Management ◽  
Cognitive Abilities ◽  
Short Form ◽  
Unruptured Intracranial Aneurysm ◽  
Significant Difference ◽  
Ability To Drive

Background: Studies have questioned the effectiveness of surgery for the management of unruptured intracranial aneurysm (uIA). Few studies have examined the ability to drive and quality of life (QOL) after surgery for uIA. Objective: This study examined the effectiveness of surgical management of uIA by measuring patients’ perceived quality of life and their cognitive abilities related to driving. Methods: Between January 2011 and January 2016 patients with a uIA were assessed using the Quality Metric Short Form 36 (SF36) and the off-road driver screening instrument DriveSafeDriveAware. Reassessments were conducted at the 6-week post-operative follow-up for surgical patients and at 12-month follow-up for surgical and conservatively managed patients. Results: 175 patients enrolled in the study, of which 112(66%) had surgical management of their aneurysm. For the surgical cases who completed all assessments (N=74), there was a trend for the DriveSafe pre-operative mean score of 108 (SD 10.7) to be lower than the 6-week and 12-month post-operative mean scores (111 SD 9.7 and 112 SD 10.2 respectively)(p=0.05). There were no significant changes in DriveAware scores at any epoch or between patient groups nor in the MCS in the surgical group.. There was a significant decline in PCS scores at 6 weeks post-operatively which recovered at 12 months (52 SD 8.1, 46 SD 6.8 and 52 SD 7.1 respectively)( p <0.01). There was no significant difference in 12-month mRS scores between the surgical cases who completed with cases who did not complete all assessments. Conclusion: Surgery for uIA did not affect cognitive abilities for driving at 6 weeks or 12 months after surgery. There was a decline in the QOL in the first months after surgery, however QOL returned to pre-surgical status 12 months after surgery. If the risk of seizures is low and there are no post-operative complications, returning to driving can be recommended.

scholarly journals Quality of life in an adolescent orthodontic population: Invisalign versus fixed appliances

2021 ◽  
Author(s):  
Richa Sharma ◽  
Robert Drummond ◽  
William Wiltshire ◽  
Robert Schroth ◽  
Milos Lekic ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Short Form ◽  
Health Impact ◽  
Fixed Appliance ◽  
Treatment Groups ◽  
Significant Difference ◽  
Orthodontic Patients ◽  
Fixed Appliances ◽  
Domain Scores

ABSTRACT Objectives To investigate adolescent orthodontic patient experiences and quality of life with fixed appliances compared to Invisalign. Materials and Methods Adolescent patients in active treatment with Invisalign or fixed appliances for a minimum of 6 months were provided with the Child Oral Health Impact Profile-Short Form 19 questionnaire, along with additional items of interest that were assessed separately. Pearson's χ2 test was used to compare responses (P &lt; .05), and unpaired t-tests (P &lt; .05) were used to test for differences in mean satisfaction, quality of life, and domain scores. Results In total, 74 patients (37 in each treatment group) participated. Overall, no significant differences were noted in the mean quality of life, satisfaction, or domain scores between the two groups. A significant difference was noted in the time taken to adjust to appliances, with the Invisalign group demonstrating faster adaptation. Additionally, the fixed appliance group was 3.8 times more likely to report missing school because of their appliance (95% confidence interval [CI]: 1.2, 12.5) and 2.7 times more likely to report having difficulty eating certain foods (95% CI: 1.1, 7.1). When the sample of females between the ages of 14 and 18 was analyzed, the Invisalign group reported feeling attractive more often than the fixed appliance group. Conclusions Both treatment groups were generally very satisfied with their treatment modality. The overall quality of life of adolescent orthodontic patients undergoing treatment with fixed appliances and Invisalign for a minimum of 6 months was similar.

scholarly journals Quality of Life in Type 2 Diabetic Patients

2014 ◽  
Vol 31 (3) ◽  
pp. 193-200 ◽  
Author(s):  
Ana Spasić ◽  
Radmila Veličković Radovanović ◽  
Aleksandra Catić Đorđević ◽  
Nikola Stefanović ◽  
Tatjana Cvetković
Keyword(s):  
Quality Of Life ◽  
Diabetes Mellitus ◽  
Short Form ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Cross Sectional ◽  
Significant Difference ◽  
Type 2 Diabetic

Summary The presence of diabetes mellitus leads to a decrease in life quality in all domains. The aim of our study was to evaluate the quality of life (QOL) in diabetic patients and the factors affecting it in type 2 diabetic mellitus patients. We conducted a cross-sectional study that included 86 patients with type 2 diabetes mellitus, in the territory of the City of Niš. Health-related QOL of patients was measured using the short form survey (SF-36) that produces an 8-scale health profile. The average duration of diabetes was 12.76±8.08 years. The best QOL in all areas was observed in patients diagnosed with diabetes less than 10 years ago p<0.05) and younger than 65 years. Male respondents perceived a better QOL compared to women, especially in the vitality and pain domains. The patients with comorbidity (93.64%) had lower QOL score in all domains. There was no significant difference in the QOL of patients with diabetes compared to the level of education. High QOL represents an ultimate goal and an important outcome of all medical interventions in diabetic patients. Factors related to lower QOL included: older age, female gender, and existence of comorbidities. Uncontrolled diabetic patients had a lower QOL than controlled diabetics.

The Effect of a 12-Week Intradialytic Exercise on Patients’ Blood Indices, Physical Performance, and Quality of Life

2020 ◽  
Vol 10 (6) ◽  
pp. 1429-1435
Author(s):  
Ji-Yeon Lee ◽  
Seung-Hui Baek ◽  
Yoon-Mi Lee ◽  
Ji-Hyung Cho ◽  
Jun-Chul Kim ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Physical Performance ◽  
Short Form ◽  
Exercise Program ◽  
Physical Component Score ◽  
Blood Indices ◽  
Sf 36 ◽  
Significant Difference ◽  
Intradialytic Exercise

This study aims to examine the effect of a 12-week intradialytic exercise program on patients’ blood indices, physical performance, and quality of life. Forty-six outpatients who were diagnosed with end-stage renal failure by a nephrologist and received hemodialysis therapy for six months or longer were recruited. The data were analyzed using SPSS and Kruskal-Wallis test was employed to analyze the continuous variables. Among blood indices, Hematocrit decreased significantly after aerobic and complex exercise; hemoglobin dropped only after complex exercise; P and Ca×P increased for a considerable amount only after complex exercise, but the postexamination results show no significant difference. As for physical performance, sit-to-stand (STS)-5 decreased with resistance and complex exercise (p < .01), while there was a significant increase in STS-30 after aerobic, resistance, and complex exercise (p < .01). 6-minute walk test (MWT) grew significantly in all groups (p < .01), but alongside gait speed, and grip strength, it diminished significantly in the non-exercise group (p< .05). When it comes to SF-36, there was a significant rise in the physical component score (PCS) (p< .01) with resistance and complex exercise. In the meantime, mental component summary (MCS) went up significantly after all types of exercises (p < .01). In contrast, Beck depression inventory (BDI) showed a significant decline only with complex exercise (p < .01). To sum up, this study suggests intradialytic complex exercise appears to be effective in enhancing Short Form (SF)-36 and BDI as well as physical performance, which is why we recommend this type of complex exercise program for hemodialysis patients.

scholarly journals A rectus diastasis prevalenciája, lehetséges rizikófaktorai és szövődményei

2017 ◽  
Vol 158 (12) ◽  
pp. 454-460 ◽  
Author(s):  
Stefánia Gitta ◽  
Zoltán Magyar ◽  
Péter Tardi ◽  
Istvánné Füge ◽  
Melinda Járomi ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Urinary Incontinence ◽  
Low Back Pain ◽  
Back Pain ◽  
Short Form ◽  
Low Back ◽  
Diastasis Recti ◽  
Significant Difference

Abstract: Introduction: There is scant knowledge on diastasis recti which occurs mostly in 3rd trimester of pregnancy. Aim: Our aim was to assign the prevalence of diastasis recti and the possible risk factors and to investigate its association with some chronical diseases, like low back pain and urinary incontinence. Method: 200 women’s interrectus distance was measured who filled out a self-made diastasis recti questionnaire, the SF-36, Oswestry Disability Index and the International Consultation on Incontinence Modular Questionnaire – Urinary Incontinence Short Form questionnaires. Results: Prevalence of the condition was 46.5%. In case of risk factors, relationship between number of deliveries and interrectus distance was significant. We found a significant difference in quality of life, in presence of low back pain and urinary incontinence between the normal and the abnormal group. Conclusions: In line with the literature we found, that diastasis recti can predispose on serious sequelae, hence on decreased quality of life. Orv. Hetil., 2017, 158(12), 454–460.

scholarly journals Mixed anxiety and depressive disorder outcomes: prospective cohort study in primary care

2011 ◽  
Vol 198 (6) ◽  
pp. 472-478 ◽  
Author(s):  
Kate Walters ◽  
Marta Buszewicz ◽  
Scott Weich ◽  
Michael King
Keyword(s):  
Quality Of Life ◽  
Primary Care ◽  
Depressive Disorder ◽  
Psychiatric Diagnosis ◽  
Short Form ◽  
General Health Questionnaire ◽  
Consultation Rate ◽  
Increased Risk ◽  
Significant Difference

BackgroundMixed anxiety and depressive disorder (MADD) is common yet ill-defined, with little known about outcomes.AimsTo determine MADD outcomes over 1 year.MethodWe recruited 250 adults attending seven London general practices with mild–moderate distress. Three groups were defined using a diagnostic interview: MADD, other ICD–10 psychiatric diagnosis, no psychiatric diagnosis. We assessed symptoms of distress (General Health Questionnaire–28), quality of life (12-item Short Form Health Survey), general practitioner (GP) diagnosis and consultation rate at baseline, 3 months and 1 year.ResultsTwo-thirds of participants with MADD had no significant psychological distress at 3 months (61%) or 1 year (69%). However, compared with those with no diagnosis, individuals had twice the risk of significant distress (incidence rate ratio 2.39, 95% CI 1.29–4.42) at 3 months but not 1 year, and persistently lower quality of life (mental health functioning). There was no significant difference in GP consultation rate/diagnosis.ConclusionsThe majority with MADD improved, but individuals had an increased risk of significant distress at 3 months and a lower quality of life. As we cannot currently predict those with a poorer prognosis these patients should be actively monitored in primary care.

scholarly journals Psychiatric morbidity, quality of life and marital satisfaction among spouse of men with opioid dependence syndrome: a study from North India

2017 ◽  
Vol 4 (2) ◽  
pp. 556
Author(s):  
Ruchi Soni ◽  
Ritesh Upadhyay ◽  
Parth Singh Meena ◽  
Mahendra Jain
Keyword(s):  
Quality Of Life ◽  
Marital Satisfaction ◽  
Psychiatric Disorder ◽  
Opioid Dependence ◽  
Short Form ◽  
Psychiatric Morbidity ◽  
Poor Quality ◽  
North India ◽  
Significant Difference

Background: Opioid dependence syndrome has deleterious consequences not only on addict but also on the members of family especially his spouse who is most vulnerable to develop significant psychiatric disorder given the intimate nature of their relationship. Addressing these issues will be beneficial as spouses are important source of moral support and assistance to the substance user’s quest toward abstinence.Methods: For psychiatric morbidity, 100 spouses of men with opioid dependence syndrome were evaluated. Severity of opioid dependence in the husbands was assessed using severity of opioid dependence questioner (SODQ). Quality of life and marital satisfaction was assessed using short form health survey 36 (SF 36) and marital satisfaction scale (MSS) respectively.Results: Data analysis reveals that 33% of spouses had a psychiatric disorder. Primarily mood and anxiety disorder was present in 22% and 9% of subjects respectively. Highly significant difference existed between cases and controls in terms of marital satisfaction (p = 0.0001) and quality of life (p≤0.05) indicating low marital satisfaction and poor quality of life in spouses of opioid dependent individuals.Conclusions: Psychological distress and psychiatric morbidity in spouses of opioid dependent men is high, with poor quality of marital life and marital satisfaction being low. Hence, interventions that aim at allaying their distress and improving their mental health can improve the condition of the substance user and contribute to a better outcome of substance abuse treatment.

scholarly journals The role of folded fibular flap in patients’ reconstruction of mandibular defects: a retrospective clinical study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ning Gao ◽  
Kun Fu ◽  
Jinghua Cai ◽  
Hao Chen ◽  
Wei He
Keyword(s):  
Quality Of Life ◽  
Psychological Health ◽  
Short Form ◽  
Life Questionnaire ◽  
Preoperative Level ◽  
Sf 36 ◽  
Retrospective Clinical Study ◽  
Significant Difference ◽  
Fibular Flap

AbstractThis study has analyzed 41 patients with mandibular ameloblastoma who underwent a partial mandibulectomy and reconstruction by folding the free fibular flap. In the preoperative and postoperative (6 months and 24 months after surgery), the Quality of Life (QOL) of these patients was assessed by using the University of Washington Quality of Life Questionnaire (UW-QOL) and the medical outcome study short form-36 (SF-36) questionnaires. SPSS 20.0 statistical software was used to conduct statistical analysis on the base data of the two groups of patients. Independent sample t test was conducted for sf-36 and UW-QOL scores at two time points in each group. The SF-36 survey showed that body pain (54.54 ± 8.10), general health (55.27 ± 7.54), and health changes (58.29 ± 9.60) decreased significantly at 6 months after surgery, but the mean score at 24 months after surgery all exceeded the preoperational level. At 24 months after the surgery, the vitality (80.41 ± 3.74), social function (81.61 ± 4.07), emotional role (82.39 ± 4.07), psychological health (81.66 ± 4.37) and total score (704.00 ± 31.53) all returned to the preoperative level, which was statistically significant compared with 6 months after surgery. However, there was no significant difference compared with the preoperative level. The UW-QOL survey showed that chewing (56.68 ± 7.23), speech (54.54 ± 7.7) and taste (62.29 ± 10.15) have significantly changed at 6 months after the surgery, and the difference was statistically significant at 24 months after surgery. Saliva generation decreased slightly (80.76 ± 3.35) at 6 months after surgery, but quickly returned to the preoperative level (81.59 ± 4.06). The total score of the patients almost recovered to the preoperative level at 24 months after surgery. The folded the fibular flap can not only repair the defects of soft tissue and bone tissue, but also restore the height of the alveolar ridge to, avoid the imbalance of crown and root ratio after implantation and reduce the occurrence of peri-implant inflammation, so that a true functional reconstruction can be realized.

scholarly journals Long-term quality of life in adults following truncus arteriosus repair

2019 ◽  
Vol 29 (6) ◽  
pp. 950-954 ◽  
Author(s):  
Hilson Tay ◽  
Phillip S Naimo ◽  
Li Huang ◽  
Tyson A Fricke ◽  
Johann Brink ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Short Form ◽  
Arterial Switch Operation ◽  
Adult Survivors ◽  
Truncus Arteriosus ◽  
Health State ◽  
Australian Population ◽  
Short Form 36 ◽  
Significant Difference

OBJECTIVES To date, few studies have assessed the quality of life following congenital cardiac surgery. In this study, we aimed at determining the quality of life after truncus arteriosus (TA) repair using the Short Form 36 questionnaire in adult survivors. METHODS Seventy-three patients (age >18 years) who underwent TA repair at the Royal Children’s Hospital, Australia were identified for the study. Of these, 42 patients (58%, 42/73) participated in the study and completed the Short Form 36 questionnaire. The results of the 8 domains and the derived health state summary score (Short Form Six Dimension, SF-6D) were compared with age-matched Australian population controls, and with patients who underwent the arterial switch operation (ASO). RESULTS Compared with the age-matched Australian population, 18- to 24-year-old TA patients (31%, 13/42) had lower scores in 6 of 8 domains; 25- to 34-year-old TA patients (36%, 15/42) scored lower in 5 of 8 domains; and 35- to 44-year-old TA patients (33%, 14/42) scored lower in 4 of 8 domains. SF-6D scores were not significantly different between TA patients and the age-matched Australian population. Compared with patients who underwent ASO, 18-to 24-year-old TA patients scored lower in 3 of 8 domains; and 25- to 34-year-old TA patients scored lower in 2 of 8 domains. There was no significant difference in SF-6D scores between TA and patients who underwent the ASO. CONCLUSIONS Adult survivors of TA have similar quality of life compared with age-matched Australian controls measured by SF-6D. Despite a higher reoperation rate in TA patients, they have similar quality of life compared with ASO patients.

scholarly journals Effects of Chemotherapy Treatment on Muscle Strength, Quality of Life, Fatigue, and Anxiety in Women with Breast Cancer

2020 ◽  
Vol 17 (19) ◽  
pp. 7289 ◽  
Author(s):  
Vitor A. Marques ◽  
João B. Ferreira-Junior ◽  
Thiago V. Lemos ◽  
Rafael F. Moraes ◽  
José Roberto de S. Junior ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Muscle Strength ◽  
Short Form ◽  
Cancer Control ◽  
Peak Torque ◽  
Knee Extension ◽  
Anxiety State ◽  
Chemotherapy Treatment

The study aimed to evaluate the effects of chemotherapy treatment on muscle strength, quality of life, fatigue, and anxiety in women with breast cancer. Nineteen women who were undergoing a chemotherapy treatment (breast cancer treatment [BCT] group, 52.2 ± 13.1 years) and 18 women without cancer (control [CNT] group, 55.8 ± 8.4 years) answered questionnaires for evaluation of fatigue (Fatigue Scale), quality of life (Short-Form Healthy Survey [SF-36] questionnaire), and anxiety (State-Trait Anxiety Inventory [IDATE]) levels. Muscle strength was also assessed by an isometric grip test and an isokinetic knee extension test. Physical limitations, social and emotional domains of quality of life were lower in the BCT group in comparison to the CNT group (p = 0.002; p = 0.003; p = 0.0003, respectively). The other domains did not differ between groups (p > 0.05). There were no differences in fatigue and anxiety levels between both the BCT and CNT groups (p > 0.05). Additionally, isometric grip strength was higher in the CNT group when compared to the BCT group (p = 0.048). However, there were no differences between the BCT and CNT groups for peak torque and total work at both 60°.s−1 (p = 0.95 and p = 0.61, respectively) and 180°.s−1 (p = 0.94 and p = 0.72, respectively). These results suggest that three cycles of chemotherapy treatment may impair handgrip isometric strength and quality of life in women with breast cancer.

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