scholarly journals Bone Marrow Adipocytes and Hematology: A Literature Review

2021 ◽  
Vol 11 (2) ◽  
pp. 123-130
Author(s):  
Nataliia Kriventsova ◽  
Alexander Shestopalov ◽  
Galina Tereshchenko
Keyword(s):  
Bone Marrow ◽  
Marrow Fat ◽  
Hematological Diseases ◽  
Active Involvement ◽  
Bone Marrow Fat ◽  
Cytokines And Chemokines ◽  
Bone Marrow Adipocytes ◽  
Number Of Publications ◽  
The Impact

This review focuses on the impact of bone marrow adipocytes on hematopoiesis and the development of hematological diseases. Bone marrow fat is a metabolically active organ capable of accumulating energy required for active hematopoiesis as well as of performing endocrine functions and participating in bone formation. Adipocytes can interact with the surrounding cells both directly and indirectly via cytokines and chemokines. Apart from their active involvement in the normal hematopoiesis, BMA have also been shown to play an important role in such diseases as leukemia, multiple myeloma and aplastic anemia. The role of fat cells in hematopoiesis is still unclear and not well studied, yet it is undoubtedly important, as demonstrated by the ever increasing number of publications supporting this conclusion.

scholarly journals Changes in Bone Marrow Fat upon Dietary-Induced Weight Loss

Nutrients ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 1509
Author(s):  
Manuela Spurny ◽  
Yixin Jiang ◽  
Solomon A. Sowah ◽  
Ruth Schübel ◽  
Tobias Nonnenmacher ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Weight Loss ◽  
Study Cohort ◽  
Marrow Fat ◽  
Bone Marrow Fat ◽  
Randomized Controlled ◽  
Cell Counts ◽  
Significant Difference ◽  
Metabolic Biomarkers ◽  
The Impact

Background: Bone marrow fat is implicated in metabolism, bone health and haematological diseases. Thus, this study aims to analyse the impact of moderate weight loss on bone marrow fat content (BMFC) in obese, healthy individuals. Methods: Data of the HELENA-Trial (Healthy nutrition and energy restriction as cancer prevention strategies: a randomized controlled intervention trial), a randomized controlled trial (RCT) among 137 non-smoking, overweight or obese participants, were analysed to quantify the Magnetic Resonance Imaging (MRI)-derived BMFC at baseline, after a 12-week dietary intervention phase, and after a 50-week follow-up. The study cohort was classified into quartiles based on changes in body weight between baseline and week 12. Changes in BMFC in respect of weight loss were analysed by linear mixed models. Spearman’s coefficients were used to assess correlations between anthropometric parameters, blood biochemical markers, blood cells and BMFC. Results: Relative changes in BMFC from baseline to week 12 were 0.0 ± 0.2%, −3.2 ± 0.1%, −6.1 ± 0.2% and −11.5 ± 0.6% for Q1 to Q4. Across all four quartiles and for the two-group comparison, Q1 versus Q4, there was a significant difference (p < 0.05) for changes in BMFC. BMFC was not associated with blood cell counts and showed only weaker correlations (<0.3) with metabolic biomarkers. Conclusion: Weight loss is associated with a decrease of BMFC. However, BMFC showed no stronger associations with inflammatory and metabolic biomarkers.

Bone marrow fat is metabolically distinct fat depot

2013 ◽  
Author(s):  
Riku Kiviranta ◽  
Tam Pham ◽  
Jarna Hannukainen ◽  
Juho Jarvelin ◽  
Anna Karmi ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Marrow Fat ◽  
Bone Marrow Fat ◽  
Fat Depot

Bone marrow fat analysis as a diagnostic tool to document ante-mortem starvation

2019 ◽  
Vol 243 ◽  
pp. 1-7 ◽  
Author(s):  
Troy I. Raglus ◽  
Bert De Groef ◽  
Simone Rochfort ◽  
Grant Rawlin ◽  
Christina McCowan
Keyword(s):  
Bone Marrow ◽  
Diagnostic Tool ◽  
Marrow Fat ◽  
Bone Marrow Fat

scholarly journals The impact of bone marrow adipocytes on osteoblast and osteoclast differentiation

IUBMB Life ◽  
2014 ◽  
Vol 66 (3) ◽  
pp. 147-155 ◽  
Author(s):  
Shanmugam Muruganandan ◽  
Christopher J. Sinal
Keyword(s):  
Bone Marrow ◽  
Osteoclast Differentiation ◽  
Bone Marrow Adipocytes ◽  
The Impact

scholarly journals Practical Approaches to Bone Marrow Fat Fraction Quantification Across Magnetic Resonance Imaging Platforms

2020 ◽  
Vol 52 (1) ◽  
pp. 298-306 ◽  
Author(s):  
Alan Bainbridge ◽  
Timothy J.P. Bray ◽  
Raj Sengupta ◽  
Margaret A. Hall‐Craggs
Keyword(s):  
Magnetic Resonance Imaging ◽  
Bone Marrow ◽  
Magnetic Resonance ◽  
Resonance Imaging ◽  
Marrow Fat ◽  
Bone Marrow Fat ◽  
Fat Fraction

scholarly journals Le rôle des entreprises et leurs comportements sur la stabilité du système financier

2021 ◽  
Vol 14 (2) ◽  
pp. 85-103
Author(s):  
Farelle Yandza Ikahaud ◽  
Mohamed El Haddad
Keyword(s):  
Bibliometric Analysis ◽  
Empirical Work ◽  
Financial System ◽  
The State ◽  
Scientific Interest ◽  
Number Of Publications ◽  
The Stability ◽  
The Impact

Investment determines the sustainability and prosperity of an economy. The paper seeks to (1) give an overview of the roles of companies on the stability of the financial system, based on existing theoretical and empirical work; and (2) to highlight the reasons which expose them to the non-application of their duties against the State. For this purpose, a bibliometric analysis using the Direct Science database was employed. The results of the analysis allowed us to study the search trend by analyzing the distribution of publications, authors, types of publications and fields of research and also showed that the themes of the study are of great scientific interest because of the surge in the number of publications on the role of companies over the last ten years averaging 76.3 per year while 1,690 were on the impact of company behaviour on the stability of the financial system.

scholarly journals Bone marrow fat is increased in chronic kidney disease by magnetic resonance spectroscopy

2015 ◽  
Vol 26 (6) ◽  
pp. 1801-1807 ◽  
Author(s):  
R. N. Moorthi ◽  
W. Fadel ◽  
G. J. Eckert ◽  
K. Ponsler-Sipes ◽  
S. M. Moe ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Bone Marrow ◽  
Magnetic Resonance ◽  
Kidney Disease ◽  
Magnetic Resonance Spectroscopy ◽  
Resonance Spectroscopy ◽  
Marrow Fat ◽  
Bone Marrow Fat
Sign in / Sign up

Export Citation Format

Share Document