scholarly journals Assessment of long distance chasing photometer (NAG-ADF-300-2) by estimating the drug atenolol with ammonium molybdate via continuous flow injection analysis

2020 ◽  
Vol 17 (1) ◽  
pp. 0078
Author(s):  
Elham N. Mezaal N. Mezaal
Keyword(s):  
Flow Injection ◽  
Flow Injection Analysis ◽  
Continuous Flow ◽  
Classical Method ◽  
Standard Addition ◽  
Calibration Graph ◽  
Ammonium Molybdate ◽  
Long Distance ◽  
Optimum Parameters

     Atenolol was used with ammonium molybdate to prove the efficiency, reliability and repeatability of the long distance chasing photometer (NAG-ADF-300-2) using continuous flow injection analysis. The method is based on reaction between atenolol and ammonium molybdate in an aqueous medium to obtain a dark brown precipitate. Optimum parameters was studied to increase the sensitivity for developed method. A linear range for calibration graph was 0.1-3.5 mmol/L for cell A and 0.3-3.5 mmol/L for cell B, and LOD 133.1680 ng/100 µL and 532.6720 ng/100 µL for cell A and cell B respectively with correlation coefficient (r) 0.9910 for cell A and 0.9901 for cell B, RSD% was lower than 1%, (n=8) for the determination of atenolol at concentration (0.5, 0.7 and 5) mmol/L respectively. The results were compared with classical method UV-Spectrophotometric at λ max=270 nm using the standard addition method via the use of t-test, at 95% confidence level. The comparison of data explain that long distance chasing photometer (NAG-ADF-300-2) is the choice with excellent extended detection and wide application.                                                                                                       

scholarly journals CFIA-Turbidimetric and Photometric Determination of Vitamin B9 (Folic acid) Using LEDs as a Source of Irradiation and Two Solar Cells as an Energy Transducer

2017 ◽  
Vol 14 (4) ◽  
pp. 773-786
Author(s):  
Baghdad Science Journal
Keyword(s):  
Folic Acid ◽  
Classical Method ◽  
Standard Addition ◽  
Photometric Determination ◽  
Calibration Graph ◽  
Ammonium Molybdate ◽  
Simple Method ◽  
Vitamin B9 ◽  
Significant Difference

A specific, sensitive and simple method was used for the determination of: vitamin B9 (Folic acid) in pure and pharmaceutical formulations using continuous flow injection analysis. The method is based on formation of ion pair compound between folic acid and ammonium molybdate in an aqueous medium to obtain a gray precipitate complex, using homemade; Ayah-6SX1-ST-2D solar cell CFI Analyzer. Optimum parameters was studied to increase the sensitivity for developed method. The linear range for the calibration graph was 0.01-0.6 mMol.L-1 of vitamin B9 and LOD was 131.994 ng/sample with correlation coefficient ( r ) of 0.9810, RSD% was lower than 0.1%, (n=9) for the determination of vitamin B9 at concentration (0.07and 0.5) mMol.L-1 respectively. The developed method was applied successfully for the determination of vitamin B9 in pharmaceutical tablets. A comparison was made between two methods: developed method and the classical UV spectrophotometric method at ?max=255 nm, by using the standard addition method via the use of paired t-test. It showed that there was no significant difference between the developed method and the classical method for determination vitamin B9 at 95% confidence level.

scholarly journals Determination of Thiocyanate by Kinetic Spectrophotometric Flow Injection Analysis

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Mohsen Keyvanfard ◽  
Khadijeh Alizad ◽  
Parinaz Elahian
Keyword(s):  
Detection Limit ◽  
Hydrochloric Acid ◽  
Flow Injection ◽  
Flow Injection Analysis ◽  
Calibration Graph ◽  
Well Water ◽  
Janus Green ◽  
Rapid Flow ◽  
Kinetic Spectrophotometric

A simple and rapid flow injection spectrophotometric method has been developed for the determination of amount of thiocyanate in wastewaters and well water samples. It is based on the reaction of thiocyanate in hydrochloric acid with janus green and bromate. Reaction was monitored spectrophotometrically by measuring janus green absorbance atλmax=554 nm. The calibration graph was linear over the range 0.02–1.0 μg mL−1and the detection limit was 0.016μg mL−1(s/n=3). The throughput was 25 samples per hour.

scholarly journals New Fluorometric Method for the Determination of Ketotifen Fumarate Using Continuous Flow Injection Analysis via ISNAG-fluorimeter

2019 ◽  
Vol 16 (2) ◽  
pp. 0353
Author(s):  
Turkie Et al.
Keyword(s):  
Flow Injection ◽  
Limit Of Detection ◽  
Classical Method ◽  
Calibration Graph ◽  
Injection System ◽  
Minimum Concentration ◽  
Ketotifen Fumarate ◽  
Fluorescence Measurements ◽  
Significant Difference

        A newly developed analytical method was conducted for the determination of Ketotifen fumarate (KTF) in pharmaceuticals drugs via quenching of continuous fluorescence of 9(10H)-Acridone (ACD). The method was applied using flow injection system of a new homemade ISNAG fluorimeter with fluorescence measurements at ± 90◦ via 2×4 solar cell. The calibration graph was linear in the range of 1-45 mmol/L, with correlation coefficient r = 0.9762 and the limit of detection 29.785 µg/sample from the stepwise dilution for the minimum concentration in the linear dynamic ranged of the calibration graph. The method was successfully applied to the determination of Ketotifen fumarate in two different pharmaceutical drugs. A comparison was made between the newly developed method analysis and the classical method using the standard addition method via the use of individual and paired t-test and F-test. It was noticed that there was no significant difference between the two methods at 95 % confidence level.

scholarly journals Determination of Phenylephrine Hydrochloride by Flow Injection Analysis with Chemiluminescence Detection

2001 ◽  
Vol 84 (1) ◽  
pp. 13-18 ◽  
Author(s):  
Yolanda Fuster Mestre ◽  
Luis Lahuerta Zamora ◽  
José Martínez Calatayud
Keyword(s):  
Flow Injection ◽  
Flow Injection Analysis ◽  
Pharmaceutical Formulations ◽  
Calibration Graph ◽  
Chemiluminescence Detection ◽  
Phenylephrine Hydrochloride ◽  
Sulfuric Acid Medium ◽  
Sample Throughput ◽  
Relative Standard

Abstract A new method is proposed for the determination of phenylephrine hydrochloride by flow injection analysis with direct chemiluminescence detection. The method is based on the oxidation of the drug by potassium permanganate in sulfuric acid medium at 80°C. The calibration graph is linear over the range 0.03–8 ppm phenylephrine hydrochloride, with a relative standard deviation (n = 51, 0.5 ppm) of 1.1% and sample throughput of 134/h. The influence of 38 different foreign compounds was tested, and the method was applied to the determination of phenylephrine hydrochloride in 8 different pharmaceutical formulations.

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