scholarly journals Determinants and Seasonality of Major Structural Birth Defects Among Newborns Delivered at Primary and Referral Hospital of East and West Gojjam Zones, North West Ethiopia 2017- 2018: Case- Control Study

2019 ◽  
Author(s):  
Binalfew Tsehay ◽  
Desalegn Shitie ◽  
Akilog Lake ◽  
Erimiyas Abebaw ◽  
Amisalu Taye ◽  
...  

Abstract Objective: Although infant mortality because of birth defect has increased in both developed and developing countries, had not got attention like other health issues at national, regional, or local levels. Documenting the risk factors that influence the occurrence of birth defects and its seasonality will help to inform the community and to develop preventive strategies for the country. Results: Factors associated with higher likelihood of a major structural birth defects included maternal age; neonates born from women living in urban; and in Dega; history of fever during pregnancy; intake of herbal medicine; and drinking alcohol. Counselling for pregnancy preparation and folic acid supplementation was found protective for the likelihood of birth defect. Key words: Birth defect, maternal illness, maternal medication use, environmental exposure

2019 ◽  
Author(s):  
Binalfew Tsehay ◽  
Desalegn Shitie ◽  
Akilog Lake ◽  
Erimiyas Abebaw ◽  
Amisalu Taye ◽  
...  

Abstract Objective: Although infant mortality because of birth defect has increased in both developed and developing countries, had not got attention like other health issues at national, regional, or local levels. Documenting the risk factors that influence the occurrence of birth defects and its seasonality will help to inform the community and to develop preventive strategies for the country. Results: Factors associated with higher likelihood of a major structural birth defects included maternal age; neonates born from women living in urban; and in Dega; history of fever during pregnancy; intake of herbal medicine; and drinking alcohol. Counselling for pregnancy preparation and folic acid supplementation was found protective for the likelihood of birth defect. Key words: Birth defect, maternal illness, maternal medication use, environmental exposure


2019 ◽  
Author(s):  
Binalfew Tsehay ◽  
Desalegn Shitie ◽  
Akilog Lake ◽  
Erimiyas Abebaw ◽  
Amisalu Taye ◽  
...  

Abstract Objective: Although infant mortality because of birth defect has increased in both developed and developing countries, had not got attention like other health issues at national, regional, or local levels. Documenting the risk factors that influence the occurrence of birth defects and its seasonality will help to inform the community and to develop preventive strategies for the country. Results: Factors associated with higher likelihood of a major structural birth defects included maternal age; neonates born from women living in urban; and in Dega; history of fever during pregnancy; intake of herbal medicine; and drinking alcohol. Counselling for pregnancy preparation and folic acid supplementation was found protective for the likelihood of birth defect. Key words: Birth defect, maternal illness, maternal medication use, environmental exposure


2019 ◽  
Author(s):  
Binalfew Tsehay ◽  
Desalegn Shitie ◽  
Akilog Lake ◽  
Erimiyas Abebaw ◽  
Amisalu Taye ◽  
...  

Abstract Objective: Although infant mortality because of birth defect has increased in both developed and developing countries, had not got attention like other health issues at national, regional, or local levels. Documenting the risk factors that influence the occurrence of birth defects and its seasonality will help to inform the community and to develop preventive strategies for the country. Results: Factors associated with higher likelihood of a major structural birth defects included maternal age; neonates born from women living in urban; and in Dega; history of fever during pregnancy; intake of herbal medicine; and drinking alcohol. Counselling for pregnancy preparation and folic acid supplementation was found protective for the likelihood of birth defect. Key words: Birth defect, maternal illness, maternal medication use, environmental exposure


2007 ◽  
Vol 38 (10) ◽  
pp. 1495-1503 ◽  
Author(s):  
R. T. Webb ◽  
A. R. Pickles ◽  
S. A. King-Hele ◽  
L. Appleby ◽  
P. B. Mortensen ◽  
...  

BackgroundFew large studies describe links between maternal mental illness and risk of major birth defect in offspring. Evidence is sparser still for how effects vary between maternal diagnoses and no previous study has assessed risk with paternal illnesses.MethodA population-based birth cohort was created by linking Danish national registers. We identified all singleton live births during 1973–1998 (n=1.45 m), all parental psychiatric admissions from 1969 onwards, and all fatal birth defects until 1 January 1999. Linkage and case ascertainment were almost complete. Relative risks were estimated using Poisson regression.ResultsRisk of fatal birth defect was elevated in relation to history of any maternal admission and also with affective disorders specifically, although the strongest effect found was with maternal schizophrenia. The rate was more than doubled in this group compared to the general population [relative risk (RR) 2.34, 95% confidence interval (CI) 1.45–3.77], which also represented a significant excess risk compared with all other admitted maternal disorders (p=0.018). Risk of death from causes other than birth defect was no higher with schizophrenia than with other maternal conditions. There was no elevation in risk of fatal birth defect if the father was admitted with schizophrenia or any other psychiatric diagnosis.ConclusionsThere are many possible explanations for a higher risk of fatal birth defect with maternal schizophrenia and affective disorder. These include genetic effects directly linked with maternal illness, lifestyle factors (diet, smoking, alcohol and drugs), poor antenatal care, psychotropic medication toxicity, and gene–environment interactions. Further research is needed to elucidate the causal mechanisms.


2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
V A Postoev ◽  
L I Menshikova ◽  
A A Usynina ◽  
A M Grjibovski ◽  
J O Odland

Abstract Introduction Periconceptional use of folic acid supplementation is an evidence-based measure of birth defects prevention. The study was aimed to assess effect of periconceptual use of folic acid on birth defect prevalence in Arkhangelsk county and to investigate socio-demographic factors, which are associated with adherence to this preventive measure. Methods A registry-based study was conducted with data from the Arkhangelsk County Birth Registry for 2012-2015. The study population included 57084 pregnancies to calculate the proportion of women taking folic acid and 53340 pregnancy outcomes without missing data to analyze related socio-demographic characteristics. Results The proportion of women followed a folic acid supplementation before pregnancy was 1.3% (95% CI: 1.2-1.4), during pregnancy - 55.8% (95%CI: 54.6-56.4). Such women had less risk to deliver a newborn with any birth defects (OR = 0,84, 95%CI: 0,75 - 0,95). Considering birth defects prevalence of 38,6 per 1000 newborns in Arkhangelsk county, number needed to prevent one case of birth defect was 142,9. Based on multivariate analysis, nulliparous married women with higher education, aged 30 or more, had a higher chance to use folic acid before and during pregnancy. The history of spontaneous abortion in the mother's medical history and the first pregnancy were negatively associated with the probability of folic acid intake both before and during pregnancy. Conclusions The compliance to periconceptional intake of folic acid among women in the region was low. A level of compliance was associated with such socio-demographic factors as age, education, marital status, gravidity and parity. The findings have direct applications in improving prenatal care in Arkhangelsk county and establishing targets for prenatal counseling. Key messages A level of compliance to primary prevention of birth defects is associated with such socio-demographic factors as age, education, marital status, gravidity and parity. Prenatal counseling in terms of birth defects prevention should be based on socio-demographic characteristics of pregnant women.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Gashaw Mehiret Wubet ◽  
Abiyu Ayalew Assefa

Abstract Background Nearly 1.9% of global blindness is caused by glaucoma and this is sadly high in Africa which is around 15% and In Ethiopia, glaucoma is responsible for 5.2% of blindness. It is also the fifth cause of blindness in Ethiopia. Scarce information is available regarding glaucoma in Ethiopia; hence we determined the proportion of glaucoma and its associated factors in North West Ethiopia which will be utilized for future related researches and different stakeholders. Methods Institution based cross-sectional study was conducted from September 1/2020 to February 30/21 among 258 adults aged 40 and above years old. The participants were selected using the systematic random sampling technique. The data was collected using an interview-administered questionnaire. Binary and Multi-variable logistic regressions were fitted to identify independent predictors of glaucoma. P-value less than 0.05 were used as a cutoff point for declaring statistical significance. Results The prevalence of glaucoma was 66(26%) with a 95% CI of 17.7, 35.4%). Individuals with Positive family history of glaucoma (AOR: 3.72, 95% CI: 1.03–3.53), age (AOR: 3.21, 95% CI: 1.92–5.99) and elevated intraocular pressure (AOR: 3.09, 95% CI: 1.45–6.59) were statistically significant contributing factors for the development of glaucoma. Conclusion The study found a relatively high proportion of glaucoma in the study area, which is primarily a disease of the elderly. Age, elevated intraocular pressure, and positive family history of glaucoma was contributing factors for the emergence of glaucoma. Therefore, establishing public awareness programs about the identified risk factors for the prevention and early detection of cases is essential.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Misganaw Fikrie Melesse ◽  
Yibelu Bazezew Bitewa ◽  
Kumneger Nigussie Dessie ◽  
Demeke Binalf Wondim ◽  
Tefera Marie Bereka

Abstract Background Every day, at least 810 women die worldwide from the complications of pregnancy and childbirth, 86% of which occurring in Southern Asia and Sub-Saharan Africa. One of the contributing factors for these problems is cultural malpractices during pregnancy and childbirth. The actual incidence of cultural malpractices in developing countries accounts for about 5–15% of maternal deaths. Thus, understanding the link between cultural affairs and maternal health is critical to saving the lives of women and their babies. Therefore, this research was aimed to assess cultural malpractices during labor and delivery and associated factors among women who had at least one history of delivery in selected Zones of the Amhara region, North West Ethiopia. Method Community based cross-sectional study was conducted on women who had at least one delivery history in Awi, West, and East Gojjam Zones from January 1 to May 30, 2020. The multistage cluster sampling technique was used to select 845 study participants. Data was collected through a pre-tested and structured interview questionnaire, entered and cleaned using EPI info version 7.2, and exported to SPSS version 23 for analysis. Bivariable and multivariable logistic regression was employed to assess the association of the variables and a P-value less than 0.05 was declared as statistically significant. Result Out of 845 women 162(19.2%) practiced nutritional taboo, 77(9.1%) women practiced abdominal massage and 273(32.3%) delivered their babies at home. Educational status of the respondents being un able to read and write (AOR = 14.35,95% CI: 3.12,65.96), husband's educational status (AOR = 3.80,95% CI: 1.24,11.64), residence (AOR = 2.93,95% CI: 1.41: 6.06), ethnicity (AOR = 2.20,95% CI:1.32, 3.67), pregnancy complications (AOR = 1.61,95% CI:1.02, 2.53), gravidity (AOR = 3.54,95% CI:1.38,9.08) and antenatal care follow up (AOR = 2.24, 95% CI:1.18,4.25) had statistically significant association with cultural malpractices during labor and delivery. Conclusion This study showed that cultural malpractices during childbirth were high in Awi, West, and East Gojjam Zones relative to the country's maternal health service utilization plan. Working on antenatal care follow-up and women and husband education in a culturally acceptable manner may reduce cultural malpractices during labor and delivery.


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